Patents by Inventor Daniel F. Voytas

Daniel F. Voytas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6720479
    Abstract: The present invention provides plant retroelements useful as molecular tools. In one embodiment, the present invention provides nucleic acids encoding gag, pol and/or env genes of plant retroelements. The elements can be used, among other uses, as building blocks of other constructs, tools to find other nucleic acid sequences and tools to transfer nucleic acid into cells.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: April 13, 2004
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: David A. Wright, Daniel F. Voytas
  • Publication number: 20040019928
    Abstract: The present invention provides nucleic acids, as well as vectors, cells, and plants (including plant parts, seeds, and embryos) containing the nucleic acids. In particular, molecular tools are provided in the form of nucleic acids that encode reverse transcriptases. The invention also features methods for manipulating such nucleic acids. In addition, the invention features methods to introduce nucleic acids containing retroelements or retroelement sequences into cells.
    Type: Application
    Filed: March 24, 2003
    Publication date: January 29, 2004
    Inventors: David A. Wright, Daniel F. Voytas
  • Publication number: 20040016018
    Abstract: The present invention provides plant retroelements useful as molecular tools. In one embodiment, the present invention provides nucleic acids encoding gag, pol and/or env genes of plant retroelements. The elements can be used, among other uses, as building blocks of other constructs, tools to find other nucleic acid sequences and tools to transfer nucleic acid into cells.
    Type: Application
    Filed: July 8, 2003
    Publication date: January 22, 2004
    Applicant: Iowa State University Research Foundation, Inc., an Iowa corporation
    Inventors: David A. Wright, Daniel F. Voytas
  • Publication number: 20030166190
    Abstract: The invention provides a family of plant retroelements as well as nucleic acids, vectors, and polypeptides relating to those retroelements.
    Type: Application
    Filed: December 10, 2002
    Publication date: September 4, 2003
    Inventors: David A. Wright, Daniel F. Voytas
  • Publication number: 20020112259
    Abstract: The present invention provides plant retroelements useful as molecular tools. In one embodiment, the present invention provides nucleic acids encoding gag, pol and/or env genes of plant retroelements. The elements can be used, among other uses, as building blocks of other constructs, tools to find other nucleic acid sequences and tools to transfer nucleic acid into cells.
    Type: Application
    Filed: September 27, 2001
    Publication date: August 15, 2002
    Applicant: Iowa State University Research Foundation, Inc.
    Inventors: David A. Wright, Daniel F. Voytas
  • Patent number: 6331662
    Abstract: The present invention provides plant retroelements useful as molecular tools. In one embodiment, the present invention provides nucleic acids encoding gag, pol and/or env genes of plant retroelements. The elements can be used, among other uses, as building blocks of other constructs, tools to find other nucleic acid sequences and tools to transfer nucleic acid into cells.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: December 18, 2001
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: David A. Wright, Daniel F. Voytas
  • Patent number: 6228647
    Abstract: The present invention provides methods for altering the integration site specificity of retrotransposons and retroviruses by modifying the integrase protein (especially via engineering its coding sequence) to include a peptide portion which interacts specifically with a protein associated with a chromosome, e.g., a transcription factor, or which interacts with a particular nucleic acid sequence. Further disclosed is a peptide portion of the integrase of Ty5 which peptide portion directs integration of Ty5 or any other retrotransposon or retrovirus into whose integrase it is included into silent chromosome regions and mutant Ty5 integrase proteins for which the insertional specificity is destroyed.
    Type: Grant
    Filed: January 15, 1999
    Date of Patent: May 8, 2001
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Daniel F. Voytas, Xiaowu Gai
  • Patent number: 5976795
    Abstract: The present disclosure provides retrotransposons and retrotransposon derivatives and methods for their uses. Specifically, the present invention provides Ty5-6p and derivatives. Ty5-6p and its derivatives integrate preferentially in the genome of eukaryotes in silent chromatin and in regions like silent chromatin. Ty5-6p insertions can be used to regulate the life span of cells, to genetically mark cells, to deliver gene therapy and to identify genes involved in development and in senescence.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: November 2, 1999
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Daniel F. Voytas, Sige Zou