Patents by Inventor Daniel Freeman

Daniel Freeman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230014027
    Abstract: A seal assembly includes a first wall extending from a compression side to a fastened side of the seal assembly, a stiffening member embedded within the first wall adjacent to the compression side of the seal assembly, and a second wall exterior of the first wall and extending from the compression side to the fastened side of the seal assembly. When the seal assembly is pressurized, the first wall and the second wall define an insulated pocket.
    Type: Application
    Filed: July 19, 2021
    Publication date: January 19, 2023
    Applicant: The Boeing Company
    Inventors: Jessica Marie-Meyer Ribble, Wesley L. Holman, Stephen R. Byrne, Amy Everson, Huilin Xie, Daniel Freeman, Genesis Marvin S. Pilarca
  • Publication number: 20220391706
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training neural networks using learned optimizers. One of method is for training a neural network layer comprising a plurality of network parameters having a plurality of dimensions each having a plurality of indices, the method comprising: maintaining a set of values corresponding to respective sets of indices of each dimension, each value representing a measure of central tendency of past gradients of the network parameters having an index in the dimension that is in the set of indices; performing a training step to obtain a new gradient for each network parameter; updating each set of values using the new gradients; and for each network parameter: generating an input from the updated sets of values; processing the input using an optimizer neural network to generate an output defining an update for the network parameter; and applying the update.
    Type: Application
    Filed: June 2, 2022
    Publication date: December 8, 2022
    Inventors: Luke Shekerjian Metz, Christian Daniel Freeman, Jascha Narain Sohl-Dickstein, Niruban Maheswaranathan, James Michael Harrison
  • Publication number: 20220381723
    Abstract: A prosthetic device includes a closed loop system for maintaining a predetermined concentration of a target ion in a region in proximity to a cell, such as a nerve cell. The device includes a controller and an ion-selective electrode assembly operatively connected to the controller, wherein the ion-selective electrode configuration is configured to sense the concentration of the target ion by potentiometric measurement and to convey the concentration to the controller. The controller is configured to modulate the current to the ion-selective electrode assembly based on the concentration of the target ion to control the concentration of the target ion so as to maintain the predetermined concentration of the target ion.
    Type: Application
    Filed: May 11, 2022
    Publication date: December 1, 2022
    Applicants: Massachusetts Institute of Technology, Charles Stark Draper Laboratory, Inc.
    Inventors: Jongyoon Han, Daniel Freeman, Matthew Flavin
  • Patent number: 11477973
    Abstract: A pest control and/or detection system generally includes an electrically conductive bait matrix including at least one carrier material that is at least one of palatable, a phagostimulant and/or consumable and/or displaceable by pests, and a plurality of electrically conductive particles. The electrically conductive particles are substantially randomly interspersed throughout the at least one carrier material. The at least one carrier material includes a thermoplastic material and/or a resin.
    Type: Grant
    Filed: April 18, 2019
    Date of Patent: October 25, 2022
    Assignee: BASF CORPORATION
    Inventors: James H. Cink, Greggory K. Storey, Kyle K. Jordan, James W. Austin, Charles E. Evanhoe, Bart Ivy, Daniel W. Engels, Daniel Freeman, Kenneth Lauffenburger, Thomas Dills, Kenneth S. Brown, Cheryl Leichter
  • Publication number: 20220324872
    Abstract: This invention relates to compounds of general Formula (I) and pharmaceutically acceptable salts thereof, in which R1, R2, R2A, R2B, R3, R4, R5A, R5B, R6, R7, R8, R9, p, q and r are as defined herein, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
    Type: Application
    Filed: June 15, 2022
    Publication date: October 13, 2022
    Applicant: Pfizer Inc.
    Inventors: Douglas Carl Behenna, Ping Chen, Kevin Daniel Freeman-Cook, Robert Louis Hoffman, Mehran Jalaie, Asako Nagata, Sajiv Krishnan Nair, Sacha Ninkovic, Martha Alicia Ornelas, Cynthia Louise Palmer, Eugene Yuanjin Rui
  • Publication number: 20220310247
    Abstract: A Virtual Reality (VR) therapeutic system for providing psychological therapy to a patient. The system includes at least a head-mounted display unit with a sound generation capability and a VR input device, and one or more computers. The system is configured to present a set of therapeutic scenarios to the patient in the virtual environment including an interaction task. A patient character interacts with a task character in the virtual environment; some of the time there is a coach character. The system determines a mental anxiety state parameter by measuring, in the virtual environment, one or more characteristics of the interaction of the patient character with the task character, monitors performance of the task, and in response to the mental anxiety state parameter and/or performance uses the coach character to provide VR feedback comprising one or both of a verbal prompt and a visual prompt in the virtual environment.
    Type: Application
    Filed: June 5, 2020
    Publication date: September 29, 2022
    Inventors: Daniel Freeman, Riana Patel, Jason Freeman, Christophe Faucherand, Mary Cordeiro, Aitor Rovira, Chung Yen Looi
  • Publication number: 20220309519
    Abstract: An inhalation device for inhaling a vaporized substance that includes metering capabilities to inform a user when a particular amount of substance has been consumed. The inhalation device can include a sensor that senses the vaporized substance and a processor that utilizes data from the sensor to meter the amount consumed. The inhalation device can also define a session, which is a time in which a user can consume a particular amount. During the session, a user can start and stop inhaling and resume inhaling. When the user stops inhaling the inhalation device will halt vapor production and will resume production when the user resumes inhaling.
    Type: Application
    Filed: June 13, 2022
    Publication date: September 29, 2022
    Applicant: INDOSE INC
    Inventors: Daniel FREEMAN, Ari FREEMAN, Jacqueline FREEMAN
  • Publication number: 20220251066
    Abstract: The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.
    Type: Application
    Filed: August 27, 2021
    Publication date: August 11, 2022
    Inventors: Michael Joseph Luzzio, Kevin Daniel Freeman-Cook, Samit Kumar Bhattacharya, Matthew Merrill Hayward, Catherine Angela Hulford, Christopher Lowell Autry, Xumiao Zhao, Jun Xiao, Kendra Louise Nelson
  • Patent number: 11396512
    Abstract: This invention relates to compounds of general Formula (I) and pharmaceutically acceptable salts thereof, in which R1, R2, R2A, R2B, R3, R4, R5A, R5B, R6, R7, R8, R9, p, q and r are as defined herein, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: July 26, 2022
    Assignee: Pfizer Inc.
    Inventors: Douglas Carl Behenna, Ping Chen, Kevin Daniel Freeman-Cook, Robert Louis Hoffman, Mehran Jalaie, Asako Nagata, Sajiv Krishnan Nair, Sacha Ninkovic, Martha Alicia Ornelas, Cynthia Louise Palmer, Eugene Yuanjin Rui
  • Publication number: 20220203351
    Abstract: A modular reaction vessel cartridge for a photometric reagent analyzer includes a hollow cuvette defining a filling chamber defining an upper orifice through which a first reagent is communicated, a dispensing opening below the upper orifice and through which a second reagent is communicated into the filling chamber, a read chamber below the dispensing opening and fluidically communicating with the filling chamber, and a dispensing control chamber above the read chamber having an exit fluidically communicating with the dispensing opening, defining a receiving opening through which the second reagent is communicated into the control chamber, and a plunger slidably and fluid-tightly disposed in the control chamber and defining therebetween a volume shaped to hold the second reagent such that, responsive to the plunger being moved into the filling chamber, fluid in the control chamber is dispensed into at least the filling chamber without fluid in the cuvette being transferred out from the cuvette.
    Type: Application
    Filed: December 31, 2020
    Publication date: June 30, 2022
    Applicant: AWARENESS TECHNOLOGY, INC.
    Inventors: Joshua E. Orlandi, Daniel P. Mammolito, Mary Freeman
  • Publication number: 20220095695
    Abstract: An inhalation device for e.g., nicotine products which receives a user input regulating the amount of nicotine the user wants to receive. Once the selected amount has been delivered to the user, the device shuts off its atomizer to conclude operation.
    Type: Application
    Filed: December 8, 2021
    Publication date: March 31, 2022
    Applicant: INDOSE INC
    Inventors: Ari FREEMAN, Daniel FREEMAN, Jacqueline FREEMAN, Benzi RONEN, John DALE, George BERNOTA, Mike DAUGHTERY, Kelly MCQUINN
  • Publication number: 20220092429
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training a neural network. One of the methods includes performing, using a plurality of training examples, a training step to obtain respective gradients of a loss function with respect to each of the parameters in the parameter tensors; obtaining a validation loss for a plurality of validation examples that are different from the plurality of training examples generating an optimizer input from at least the respective gradients and the validation loss; processing the optimizer input using an optimizer neural network to generate an output defining a respective update for each of the parameters in the parameter tensors of the neural network; and for each of the parameters in the parameter tensors, applying the respective update to a current value of the parameter to generate an updated value for the parameter.
    Type: Application
    Filed: September 21, 2021
    Publication date: March 24, 2022
    Inventors: Luke Shekerjian Metz, Niruban Maheswaranathan, Christian Daniel Freeman, Benjamin Poole, Jascha Narain Sohl-Dickstein
  • Publication number: 20220068623
    Abstract: Electrospray devices and methods of fabricating electrospray devices are described
    Type: Application
    Filed: August 31, 2020
    Publication date: March 3, 2022
    Applicant: Massachusetts Institute of Technology
    Inventors: Melissa Alyson Smith, Donna-Ruth Yost, Daniel Freeman, Noah Siegel, Paulo C. Lozano
  • Publication number: 20220005008
    Abstract: A key-duplicating system comprises a network that includes a multiplicity of kiosks at a multiplicity of different locations, each of the kiosks having a customer interface and a processor coupled to the customer interface. A remote central server coupled to the kiosks is adapted to receive, from the kiosks, information identifying master keys to be duplicated.
    Type: Application
    Filed: September 17, 2021
    Publication date: January 6, 2022
    Applicant: THE HILLMAN GROUP, INC.
    Inventor: Daniel FREEMAN
  • Patent number: 11213687
    Abstract: This disclosure provides systems and methods for delivering a neural stimulation pulse. A neural implant device can include an energy harvesting circuit configured to receive an input signal and generate an electrical signal based on the received input signal. A diode rectifier in series with the energy harvesting circuit can rectify the electrical signal. The energy harvesting circuit and the diode rectifier can be encapsulated within a biocompatible electrically insulating material. A neural electrode can be exposed through the biocompatible electrically insulating material. The neural electrode can be configured to deliver a neural stimulation pulse. The neural implant device can have a volume that is less than about 1.0 cubic millimeter.
    Type: Grant
    Filed: March 23, 2016
    Date of Patent: January 4, 2022
    Assignee: THE CHARLES STARK DRAPER LABORATORY, INC.
    Inventors: Jonathan Bernstein, Daniel Freeman, Reed Irion, Brett Ingersoll, Amy Duwel, Andrew Czarnecki, Brian Daniels, Anilkumar Harapanahalli Achyuta, Bryan McLaughlin
  • Patent number: 11203594
    Abstract: This invention relates to compounds of general Formula I in which A, R1, R2, R3 and R4 are as defined herein, and the pharmaceutically acceptable salts thereof; to pharmaceutical compositions comprising such compounds and salts; to methods of using such compounds, salts and compositions for treating pulmonary hypertension and related diseases, like pulmonary arterial hypertension; to methods of using such compounds, salts and compositions for treating abnormal cell growth, such as cancer; and to processes to make such compounds, salts and compositions.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: December 21, 2021
    Assignee: Pfizer Inc.
    Inventors: Samit Kumar Bhattacharya, Douglas Carl Behenna, Kimberly O. Cameron, Ping Chen, John M. Curto, Kevin Daniel Freeman-Cook, Mehran Jalaie, Robert Steven Kania, Yajing Lian, Sajiv Krishnan Nair, Cynthia Louise Palmer, Martin Youngjin Pettersson, Eugene Yuanjin Rui, Matthew Sammons, Qingyi Yang, Liying Zhang
  • Patent number: 11170356
    Abstract: A key-duplicating system comprises a network that includes a multiplicity of kiosks at a multiplicity of different locations, each of the kiosks having a customer interface and a processor coupled to the customer interface. A remote central server coupled to the kiosks is adapted to receive, from the kiosks, information identifying master keys to be duplicated. A key analysis module uses the information identifying master keys to be duplicated to derive information required to produce duplicates of the identified master keys, and a key duplicating module uses that information to produce duplicates of said identified master keys.
    Type: Grant
    Filed: February 19, 2020
    Date of Patent: November 9, 2021
    Assignee: The Hillman Group, Inc.
    Inventor: Daniel Freeman
  • Publication number: 20210269425
    Abstract: This invention relates to compounds of Formula (I) and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.
    Type: Application
    Filed: April 20, 2021
    Publication date: September 2, 2021
    Applicant: Pfizer Inc.
    Inventors: Douglas Carl Behenna, Kevin Daniel Freeman-Cook, Robert Louis Hoffman, Asako Nagata, Sacha Ninkovic, Scott Channing Sutton
  • Publication number: 20210261530
    Abstract: This invention relates to compounds of Formula (I) and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.
    Type: Application
    Filed: April 20, 2021
    Publication date: August 26, 2021
    Applicant: Pfizer Inc.
    Inventors: Douglas Carl Behenna, Kevin Daniel Freeman-Cook, Robert Louis Hoffman, Asako Nagata, Sacha Ninkovic, Scott Channing Sutton
  • Publication number: 20210258881
    Abstract: Methods and systems in which a portable electronic device can be voice activated are disclosed. The portable electronic device can be a multi-function electronic device. The voice activation can be robust and context sensitive. The voice activation can also be utilized without any preparatory user action with respect to the portable electronic device. The portable electronic device can also interact with a media system.
    Type: Application
    Filed: April 19, 2021
    Publication date: August 19, 2021
    Inventors: Daniel FREEMAN, Derek B. BARRENTINE