Abstract: An external defibrillator system for assisting manual delivery of chest compressions and ventilations to a patient by a rescuer as cardiopulmonary resuscitation (CPR) includes a speaker, and a processor, memory, and associated circuitry coupled to the speaker. The processor is configured to initiate prompting for the chest compressions and the ventilations manually delivered to the patient by the rescuer as CPR, control the speaker to generate first auditory cues for the chest compressions, and control the speaker to generate second auditory cues for the ventilations with a different sound than the first auditory cues for the chest compressions. The first auditory cues and the second auditory cues assist the rescuer in timing the delivery of the chest compressions and the ventilations.

Abstract: An object processing system is disclosed that includes a mobile system for moving from a proximal base toward a plurality of objects to be processed, and a programmable motion device supported on the mobile unit at a proximal end of the programmable motion device, the programmable motion device including an end-effector at a distal end thereof, the end-effector including a first stationary portion that remains stationary with respect to the distal end of the programmable motion device, and a second movable portion that moves with respect to the first stationary portion, the second movable portion for contacting at least one object of the plurality of objects for urging the at least one object from the plurality of objects toward the mobile system.

Abstract: A seal assembly includes a first wall extending from a compression side to a fastened side of the seal assembly, a second wall interior of the first wall and extending from the compression side to the fastened side of the seal assembly, and a stiffening member embedded within the second wall adjacent to the compression side of the seal assembly. When the seal assembly is pressurized, the first wall and the second wall define an insulated pocket.

Abstract: This invention relates to compounds of Formula (I) and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

Abstract: A build system for compiling and building software projects includes an integrity verification system that serves as a gate for whether to add code to a repository. When the build system receives a software package, the integrity verification system determines an integrity level for the received software package, which may be based on the intended use of the software and how other pieces of software depend on the software package. The integrity verification system determines whether the software package meets the requirements of the determined integrity level, e.g., in terms of code review, code testing, adherence to best practices, etc.

Abstract: Methods and systems in which a portable electronic device can be voice activated are disclosed. The portable electronic device can be a multi-function electronic device. The voice activation can be robust and context sensitive. The voice activation can also be utilized without any preparatory user action with respect to the portable electronic device. The portable electronic device can also interact with a media system.

Abstract: An inhalation device for inhaling a vaporized substance that includes metering capabilities to inform a user when a particular amount of substance has been consumed. The inhalation device can include a sensor that senses the vaporized substance and a processor that utilizes data from the sensor to meter the amount consumed. The inhalation device can also define a session, which is a time in which a user can consume a particular amount. During the session, a user can start and stop inhaling and resume inhaling. When the user stops inhaling the inhalation device will halt vapor production and will resume production when the user resumes inhaling.

Abstract: Methods and systems in which a portable electronic device can be voice activated are disclosed. The portable electronic device can be a multi-function electronic device. The voice activation can be robust and context sensitive. The voice activation can also be utilized without any preparatory user action with respect to the portable electronic device. The portable electronic device can also interact with a media system.

Abstract: The invention relates to 4-((6-(2,2-Difluoroethyl)-8-(2-hydroxy-2-methylcyclopentyl)-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)piperidine-1-sulfonamide or pharmaceutically acceptable salts thereof, to compositions containing them, to processes for their preparation, to intermediates used in such processes, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer. The disclosure also relates to its crystalline form 1, to pharmaceutical compositions comprising form 1, and to the use of form 1 for the treatment of cancers.

Abstract: The present invention relates to a compound of the formula I wherein R1 to R6, A, B, n and m are as defined herein. Such novel sulfonyl amide derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. This invention also relates to a method of using such compounds in the treatment of abnormal cell growth in mammals, especially humans, and to pharmaceutical compositions containing such compounds.

Abstract: A key-duplicating system comprises a network that includes a multiplicity of kiosks at a multiplicity of different locations, each of the kiosks having a customer interface and a processor coupled to the customer interface. A remote central server coupled to the kiosks is adapted to receive, from the kiosks, information identifying master keys to be duplicated. A key analysis module uses the information identifying master keys to be duplicated to derive information required to produce duplicates of the identified master keys, and a key duplicating module uses that information to produce duplicates of said identified master keys.

Abstract: An inhalation device for e.g., nicotine products which receives a user input regulating the amount of nicotine the user wants to receive. Once the selected amount has been delivered to the user, the device shuts off its atomizer to conclude operation.

Abstract: This invention relates to compounds of Formula (I) and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

Abstract: Methods and systems in which a portable electronic device can be voice activated are disclosed. The portable electronic device can be a multi-function electronic device. The voice activation can be robust and context sensitive. The voice activation can also be utilized without any preparatory user action with respect to the portable electronic device. The portable electronic device can also interact with a media system.

Abstract: This invention relates to compounds of Formula (I) and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.

Abstract: Electrospray devices and methods of fabricating electrospray devices are described.

Abstract: Methods and systems in which a portable electronic device can be voice activated are disclosed. The portable electronic device can be a multi-function electronic device. The voice activation can be robust and context sensitive. The voice activation can also be utilized without any preparatory user action with respect to the portable electronic device. The portable electronic device can also interact with a media system.

Abstract: The present disclosure provides a computer-implemented method for determining an optimized list of sets of hyperparameter values for application to an additional machine learning task. The method includes obtaining data describing a plurality of different machine learning tasks. The method includes obtaining a plurality of candidate sets of hyperparameter values. The method includes determining an ordered list of sets of hyperparameters selected from the plurality of candidate sets of hyperparameter values, wherein the ordered list of sets of hyperparameters minimizes an aggregate loss over the plurality of different machine learning tasks. The method includes storing the ordered list of sets of hyperparameters for use in training an additional machine learning model to perform an additional machine learning task.

Abstract: A seal assembly includes a first wall extending from a compression side to a fastened side of the seal assembly, a stiffening member embedded within the first wall adjacent to the compression side of the seal assembly, and a second wall exterior of the first wall and extending from the compression side to the fastened side of the seal assembly. When the seal assembly is pressurized, the first wall and the second wall define an insulated pocket.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training neural networks using learned optimizers. One of method is for training a neural network layer comprising a plurality of network parameters having a plurality of dimensions each having a plurality of indices, the method comprising: maintaining a set of values corresponding to respective sets of indices of each dimension, each value representing a measure of central tendency of past gradients of the network parameters having an index in the dimension that is in the set of indices; performing a training step to obtain a new gradient for each network parameter; updating each set of values using the new gradients; and for each network parameter: generating an input from the updated sets of values; processing the input using an optimizer neural network to generate an output defining an update for the network parameter; and applying the update.