Patents by Inventor Daniel Hunziker

Daniel Hunziker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic compounds as ATX inhibitors
    Patent number: 10882857
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, A, X, m and n are as defined herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: January 5, 2021
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jérôme Hert, Daniel Hunziker, Patrizio Mattei, Markus Rudolph, Petra Schmitz, Patrick Di Giorgio
  • Octahydro-cyclobuta[1,2-c;3,4-c?]dipyrrol-2-yl
    Patent number: 10849881
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, Y and R2 are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: June 4, 2018
    Date of Patent: December 1, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Patrizio Mattei, Daniel Hunziker, Patrick Di Giorgio, Jerome Hert, Markus Rudolph, Lisha Wang
  • BICYCLIC DERIVATIVES
    Publication number: 20200339570
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, Y, A, W, R2, m, n, p and q are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: March 13, 2020
    Publication date: October 29, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jerome HERT, Daniel HUNZIKER, Patrizio MATTEI, Harald MAUSER, Guozhi TANG, Lisha WANG
  • PHENOXYMETHYL DERIVATIVES
    Publication number: 20200339522
    Abstract: The invention provides novel compounds having the general formula (I) wherein RA, RB, RC, RC1 and W are as defined herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: March 6, 2020
    Publication date: October 29, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jerome HERT, Daniel HUNZIKER, Holger KUEHNE, Thomas LUEBBERS, Rainer E. MARTIN, Patrizio MATTEI, Werner NEIDHART, Hans RICHTER, Markus RUDOLPH, Emmanuel PINARD
  • Bicyclic compounds as ATX inhibitors
    Patent number: 10800786
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: April 10, 2019
    Date of Patent: October 13, 2020
    Assignee: Hoffman-La Roche Inc.
    Inventors: Patrizio Mattei, Jerome Hert, Daniel Hunziker, Markus Rudolph, Petra Schmitz, Patrick Di Giorgio
  • BICYCLIC QUINAZOLINONE DERIVATIVES
    Publication number: 20200317624
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R12, R13, R14, A1, A2, A3, n and m are as described herein.
    Type: Application
    Filed: February 18, 2020
    Publication date: October 8, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jerome HERT, Daniel HUNZIKER, Christoph KURATLI, Rainer E. MARTIN, Patrizio MATTEI, Alexander Lee SATZ
  • Bicyclic compounds as ATX inhibitors
    Patent number: 10787459
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R9, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: April 10, 2019
    Date of Patent: September 29, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Patrick Di Giorgio, Jerome Hert, Daniel Hunziker, Patrizio Mattei, Markus Rudolph, Petra Schmitz
  • BICYCLIC COMPOUNDS AS DUAL ATX/CA INHIBITORS
    Publication number: 20200291038
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R9, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: June 1, 2020
    Publication date: September 17, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Jerome HERT, Daniel HUNZIKER, Patrizio MATTEI, Markus RUDOLPH, Petra Schmitz, Christoph ULLMER
  • Bicyclic compounds as dual ATX/CA inhibitors
    Patent number: 10738053
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R9, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: August 11, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jerome Hert, Daniel Hunziker, Patrizio Mattei, Markus Rudolph, Petra Schmitz, Christoph Ullmer
  • BICYCLIC COMPOUNDS AS DUAL ATX/CA INHIBITORS
    Publication number: 20200223854
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
    Type: Application
    Filed: March 27, 2020
    Publication date: July 16, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Patrick DI GIORGIO, Jerome HERT, Daniel HUNZIKER, Patrizio MATTEI, Markus RUDOLPH, Petra SCHMITZ, Christoph ULLMER
  • BICYCLIC COMPOUNDS AS AUTOTAXIN (ATX) AND LYSOPHOSPHATIDIC ACID (LPA) PRODUCTION INHIBITORS
    Publication number: 20200216457
    Abstract: Compounds of formula (I) wherein R1, R2, A, W, m, n, p and q are as described herein, compositions including the compounds and methods of using the compounds as autotaxin inhibitors.
    Type: Application
    Filed: March 23, 2020
    Publication date: July 9, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Patrick DI GIORGIO, Jerome HERT, Daniel HUNZIKER, Holger KUEHNE, Patrizio MATTEI, Markus RUDOLPH
  • DIAZASPIROCYCLOALKANE AND AZASPIROCYCLOALKANE
    Publication number: 20200207769
    Abstract: Compounds having the general formula (I) wherein R1, R2, Y and W are as described herein, compositions including the compounds and methods of using the compounds as autotaxin inhibitors.
    Type: Application
    Filed: March 12, 2020
    Publication date: July 2, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Daniel HUNZIKER, Patrizio MATTEI, Harald MAUSER, Marco PRUNOTTO, Christoph ULLMER
  • CONDENSED [1,4] DIAZEPINE COMPOUNDS AS AUTOTAXIN (ATX) AND LYSOPHOSPHATIDIC ACID (LPA) PRODUCTION INHIBITORS
    Publication number: 20200199155
    Abstract: Compounds of formula (I) wherein R1, R2, A1 and A2 are as described herein, compositions including the compounds and methods of using the compounds as autotaxin inhibitors.
    Type: Application
    Filed: March 2, 2020
    Publication date: June 25, 2020
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Daniel HUNZIKER, Jerome HERT, Holger KUEHNE, Patrizio MATTEI, Markus RUDOLPH
  • Bicyclic quinazolinone derivatives
    Patent number: 10676446
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R12, R13, R14, A1, A2, A3, n and m are as described herein.
    Type: Grant
    Filed: October 10, 2017
    Date of Patent: June 9, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jerome Hert, Daniel Hunziker, Christoph Kuratli, Rainer E. Martin, Patrizio Mattei, Alexander Lee Satz
  • Bicyclic derivatives
    Patent number: 10669268
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, Y, A, W, R2, m, n, p and q are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: May 1, 2017
    Date of Patent: June 2, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Jerome Hert, Daniel Hunziker, Patrizio Mattei, Harald Mauser, Guozhi Tang, Lisha Wang
  • Condensed [1,4] diazepine compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors
    Patent number: 10669285
    Abstract: Compounds of formula (I) wherein R1, R2, A1 and A2 are as described herein, compositions including the compounds and methods of using the compounds as autotaxin inhibitors.
    Type: Grant
    Filed: September 21, 2016
    Date of Patent: June 2, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Daniel Hunziker, Jerome Hert, Holger Kuehne, Patrizio Mattei, Markus Rudolph
  • Bicyclic compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitors
    Patent number: 10654857
    Abstract: Compounds of formula (I) wherein R1, R2, A, W, m, n, p and q are as described herein, compositions including the compounds and methods of using the compounds as autotaxin inhibitors.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: May 19, 2020
    Assignee: Hoffman-La Roche Inc.
    Inventors: Patrick Di Giorgio, Jerome Hert, Daniel Hunziker, Holger Kuehne, Patrizio Mattei, Markus Rudolph
  • Bicyclic compounds as dual ATX/CA inhibitors
    Patent number: 10647719
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, Y, W, m, n, p and q are as defined herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: May 12, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Patrick Di Giorgio, Jerome Hert, Daniel Hunziker, Patrizio Mattei, Markus Rudolph, Petra Schmitz, Christoph Ullmer
  • Phenoxymethyl derivatives
    Patent number: 10640472
    Abstract: The invention provides novel compounds having the general formula (I) wherein RA, RB, RC, RC1 and W are as defined herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: May 5, 2020
    Assignee: Hoffman-La Roche Inc.
    Inventors: Jerome Hert, Daniel Hunziker, Holger Kuehne, Thomas Luebbers, Rainer E. Martin, Patrizio Mattei, Werner Neidhart, Hans Richter, Markus Rudolph, Emmanuel Pinard
  • Diazaspirocycloalkane and azaspirocycloalkane
    Patent number: 10633384
    Abstract: Compounds having the general formula (I) wherein R1, R2, Y and W are as described herein, compositions including the compounds and methods of using the compounds as autotaxin inhibitors.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: April 28, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Daniel Hunziker, Patrizio Mattei, Harald Mauser, Marco Prunotto, Christoph Ullmer