Abstract: A power tool includes a motor having an output shaft that defines an axis, a drive train connected to the output shaft and operable to drive a tool output and a housing at least partially surrounding the motor and the drive train. The power tool further includes a reference disk fixed to the housing, a collar including internal teeth that engage at least a portion of the drive train and a torque transducer having a hub, a web and a rim. The torque transducer is positioned between the collar and the reference disk such that the rim is connected to the collar and the hub is connected to the reference disk. The web defines a first thickness measured parallel to the axis and the rim defines a second thickness measured in a radial direction with respect to the axis, such that the second thickness is greater than the first thickness.

Abstract: A cuffed silicone tracheostomy tube has two tapered recesses (17) and (18) on its outer surface in which opposite ends (7) and (8) of a resilient cuff 6 are bonded using an adhesive or solvent. Two shallow ribs (22) and (23) extend around the tube on the inner edge of each recess (17) and (18), projecting outwardly to prevent the adhesive or solvent spreading onto the inflatable portion (10) of the cuff (6). The cuff (6) has several shallow ribs (9) extending around the cuff and spaced along its inflatable portion (10) to promote even inflation.

Abstract: A tracheal tube is made by the attachment proximate to its patient end an inverted cuff, so that the flash lines that result from the molding of the cuff is hidden from view, and any loose material from the flash lines of the cuff is trapped within the cuff, instead of falling into the patient. The smooth surface of the inverted cuff also prevents potential secretion buildup on the cuff and facilitates the cleaning of the tracheal tube.

Abstract: Methods and mechanisms for shaking containers are disclosed. The shaking motion can be made to vary in a dynamic fashion so that the different components within the container are not made to separate, as if subjected to the processing of a centrifuge. Such dynamic motion can appear to be random. A cantilevered base plate or other type of based place can be coupled to a base. A motor can be coupled to the base plate and configured to rotate a generally vertical shaft. A cam or other type of wheel can be coupled to the shaft and configured to eccentrically rotate about the shaft, wherein the wheel is configured to rotate within a bearing. A container base is coupled to the bearing such that the container base is configured to translate or otherwise move is general accordance with the eccentric rotation of the cam. The container base can be configured to tilt based at least in part on the translation of the container base.

Abstract: An apparatus and method for controlling radial runout between stacked disk portions (14, 18) and providing a cylindrical pin (20) having at least two diameters (22, 24). The pin is dimensioned and configured to permit the disk portions, which have different center hole dimensions, to be indexed such that a center hole of each disk portion is received by a separate diameter of the pin. The disk portions are maintained in spatial relationship as provided by the pin by spot curing a portion of the adhesive.

Abstract: A system and method for defining and enforcing a security policy. Security mechanism application specific information for each security mechanism is encapsulated as a key and exported to a semantic layer. Keys are combined to form key chains within the semantic layer. The key chains are in turn encapsulated as keys and passed to another semantic layer. A security policy is defined by forming key chains from keys and associating users with the key chains. The security policy is translated and exported to the security mechanisms. The security policy is then enforced via the security mechanisms.

Abstract: A capless retractable sealed marking instrument has a sealed chamber incorporated in a marker casing. The sealed chamber includes a chamber, a wiper ring, and an annular rim and a seal portion with a cross-slit aperture defining surfaces or flaps which are moved out of contact by a linearly-advanced marker nib to open the seal for extension of the marker nib. The configuration of the disk provides positive sealing force between the lateral sealing surfaces of the seal flaps. Retraction of the marker nib draws the flaps back into the sealed chamber configuration to protect the marker nib and cartridge from atmospheric degradation.

Abstract: The present invention relates to the identification, the isolation and the use of molecules interfering with the function(s) mediated by the poliovirus receptor (PVR) on cells. The molecules can be used for the treatment of cells having a metastatic potential, metastasis and cancer. Further methods are provided that are useful for identifying and isolating molecules which have the capacity to modulate PVR mediated adhesion or invasion potential of cells.

Abstract: The present invention relates to molecules interfering with the function of neuropilin-1 in the context of angiogenesis and the treatment of cancer. Molecules, polypeptides, antibodies, compositions and methods are provided that are useful for reducing, inhibiting or treating angiogenesis, the invasion of blood vessels into tumors, and/or the invasion or the metastatic potential of specific tumor cells. Additionally, a method is provided that allows identifying molecules, which interfere with the functionality of neuropilin-1. Furthermore, a method is provided that allows determining whether a naturally occuring tumor cell depends on functional neuropilin-1 for its invasiveness and/or metastatic potential.

Abstract: The present invention describes inhibitors of extracellular Hsp90. The inhibition of extracellular Hsp90 leads to a reduction of the invasiveness of the tumor cells. Furthermore, the invention relates to the use of molecules inhibiting extracellular Hsp90 function for the manufacture of a medicament for the treatment or prevention of invasion and/or metastatic potential of cancer cells.

Abstract: The present invention relates to a family of neuronal nicotinic acetylcholine receptors comprised of neuronal agonist and non-agonist binding subunits, and DNA sequences encoding such subunits. These novel neuronal nicotinic acetylcholine receptor subunits include the agonist binding subunits alpha2, alpha3, alpha4, and alpha5, plus non-agonist binding subunits beta2, beta3 and beta4. Representative cDNA clones that contain the DNA sequences of the invention have been deposited with the American Type Culture Collection for patent purposes.

Abstract: Operations relating to objects in a window [301] are automatically included in the window based on the capabilities of the window and based on the resources required to implement the operations. The operations are stored in an operations repository [303]. An operations manager component [302] interfaces the windows [301] and the operations repository [303]. The operations may be operations related to elements of a telecommunications network and may be made available to the end-user by automatically adding buttons to menus in the window that invoke the operations.

Abstract: Nearly-random electron motion in the primary wire of a transformer is amplified by that transformer, and the varying peaks of voltage drive some current pulses through a rectifying diode. These pulses charge a capacitor, and that charge can provide electrical energy through output wires, to do useful work elsewhere.

Abstract: A display device is provided which permits viewing of both hardcopy and digital images. An embodiment of an image viewing station comprises a housing having an internal light source and a light transmissive display panel coupled to the housing such that light from the internal light source passes therethrough. Hardcopy images affixed to an outer surface of the display panel may be transilluminated by the light passing through the display panel. Digital images may also be displayed on the display panel, by projecting the digital images onto either the inner or outer surface of the display panel. Alternatively, the panel could include a light emitting or light transmissive display panel, such as a liquid crystal display or an electroluminescent panel. Light emitted by the display panel may be sufficient to transilluminate a hardcopy image disposed on an outer surface of the display panel.

Abstract: A system for displaying an Interchangeable Holiday Theme Address Sign. The system includes a waterproof display enclosure capable of holding a variety of holiday, sports or personal message displays/logos with or without a personal street address. The waterproof enclosure has an opening for changing the holiday or personal message display. The displays can be easily changed simply by opening the enclosure and replacing it with another display.

Abstract: The present invention relates to a family of neuronal nicotinic acetylcholine receptors comprised of neuronal agonist and non-agonist binding subunits, and DNA sequences encoding such subunits. These novel neuronal nicotinic acetylcholine receptor subunits include the agonist binding subunits alpha2, alpha3, alpha4, and alpha5, plus non-agonist binding subunits beta2, beta3 and beta4. Representative cDNA clones that contain the DNA sequences of the invention have been deposited with the American Type Culture Collection for patent purposes.