Patents by Inventor Daniel L. Cox

Daniel L. Cox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190358439
    Abstract: In another example, a bioresorbable implant for use in a nasal region includes one or more bioresorbable polymers, and a pharmaceutical composition coupled to the one or more bioresorbable polymers. A release rate of the pharmaceutical composition is related to a degradation rate of the one or more bioresorbable polymers.
    Type: Application
    Filed: May 16, 2019
    Publication date: November 28, 2019
    Inventors: Gene Michal, Daniel L. Cox, Piyush Arora, Michael S. Mirizzi, Scott Baron
  • Publication number: 20190314488
    Abstract: The subject invention pertains to isolated influenza virus that is capable of infecting canids and causing respiratory disease in the canid. The subject invention also pertains to compositions and methods for inducing an immune response against an influenza virus of the present invention. The subject invention also pertains to compositions and methods for identifying a virus of the invention and diagnosing infection of an animal with a virus of the invention.
    Type: Application
    Filed: April 12, 2019
    Publication date: October 17, 2019
    Inventors: PATTI CYNTHIA CRAWFORD, PAUL J. GIBBS, EDWARD J. DUBOVI, RUBEN OMAR DONIS, JACQUELINE KATZ, ALEXANDER I. KLIMOV, NALLAKANNU P. LAKSHMANAN, MELISSA ANNE LUM, DANIEL GHISLENA EMIEL GOOVAERTS, MARK WILLIAM MELLENCAMP, NANCY J. COX, WILLIAM L. CASTLEMAN
  • Patent number: 9636486
    Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: May 2, 2017
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Paul M. Consigny, William E. Webler, Gustavo D. Cipolla, Gordon S. Stewart, Benjamyn Serna, Daniel L. Cox
  • Patent number: 9339634
    Abstract: A catheter configured for delivering an agent to a patient's vessel wall is described. The catheter includes an inflatable balloon substantially covered by a expandable cage such that when the inflatable balloon is inflated the expandable cage substantially surrounds an outer surface of the inflated balloon. The inflatable balloon is configured to be deployed within a lumen against a lumen wall and separated from the lumen wall by the expandable cage in an expanded state, and is adapted to provide an agent delivery to a treatment site, and the expandable cage is further collapsible and is removable from said lumen.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: May 17, 2016
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Daniel L. Cox
  • Publication number: 20160074635
    Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.
    Type: Application
    Filed: November 25, 2015
    Publication date: March 17, 2016
    Inventors: Paul M. Consigny, William E. Webler, Gustavo D. Cipolla, Gordon S. Stewart, Benjamyn Serna, Daniel L. Cox
  • Patent number: 9216271
    Abstract: A catheter configured for delivering an agent to a patient's vessel wall is described. The catheter includes an inflatable balloon substantially covered by a expandable cage such that when the inflatable balloon is inflated the expandable cage substantially surrounds an outer surface of the inflated balloon. The inflatable balloon is configured to be deployed within a lumen against a lumen wall and separated from the lumen wall by the expandable cage in an expanded state, and is adapted to provide an agent delivery to a treatment site, and the expandable cage is further collapsible and is removable from said lumen.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: December 22, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Daniel L. Cox
  • Patent number: 9216027
    Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.
    Type: Grant
    Filed: October 14, 2013
    Date of Patent: December 22, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Paul M. Consigny, William E. Webler, Gustavo D. Cipolla, Gordon Stewart, Benny Serna, Daniel L. Cox
  • Publication number: 20150126973
    Abstract: Embodiments of a method and apparatus to prevent reperfusion injury. In one embodiment, blood flow proximal to a lesion is occluded. An infusion catheter is advanced to a region distal to the lesion and an anti-reperfusion injury drug is delivered. The lesion may then be treated with a dilating device to reintroduce blood flow to the region distal to the lesion.
    Type: Application
    Filed: January 5, 2015
    Publication date: May 7, 2015
    Inventors: Daniel L. Cox, Hongzhi Bai, Paul Consigny, Jessica G. Chiu
  • Patent number: 8956401
    Abstract: A stent for implantation in a body lumen for protecting from rupture a fibrous cap in order to treat vulnerable plaque. One embodiment of the stent achieves staged expansion through stronger and weaker circumferential regions, and includes optional anchors positioned at the circumferential transition between the stronger and weaker regions. During the first stage expansion, the weaker region expands moving the anchors laterally apart. The anchors straddle the fibrous cap and embed into the vessel wall. The second stage expansion of the stent exerts gentler stresses by the weaker region against the fibrous cap while the stronger region exerts greater stresses on the remainder of the vessel wall to open the vessel.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: February 17, 2015
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Daniel L. Cox, Christopher Feezor
  • Patent number: 8956323
    Abstract: Embodiments of a method and apparatus to prevent reperfusion injury. In one embodiment, blood flow proximal to a lesion is occluded. An infusion catheter is advanced to a region distal to the lesion and an anti-reperfusion injury drug is delivered. The lesion may then be treated with a dilating device to reintroduce blood flow to the region distal to the lesion.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: February 17, 2015
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Daniel L. Cox, Hongzhi Bai, Paul Consigny, Jessica G. Chiu
  • Publication number: 20140046253
    Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.
    Type: Application
    Filed: October 14, 2013
    Publication date: February 13, 2014
    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
    Inventors: Paul M. Consigny, William E. Webler, Gustavo D. Cipolla, Gordon Stewart, Benny Serna, Daniel L. Cox
  • Publication number: 20130303496
    Abstract: The present invention relates to the treatment of vascular lesions using low doses of an mTOR inhibitor together with a low dose of a glucocorticoid on an implantable medical device, wherein the treatment is particularly beneficial when the patient is a diabetic or is suffering from an abnormally long or diffuse lesion.
    Type: Application
    Filed: May 8, 2012
    Publication date: November 14, 2013
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Daniel L. Cox, Stephen D. Pacetti
  • Publication number: 20130289708
    Abstract: A stent for implantation in a body lumen for protecting from rupture a fibrous cap in order to treat vulnerable plaque. One embodiment of the stent achieves staged expansion through stronger and weaker circumferential regions, and includes optional anchors positioned at the circumferential transition between the stronger and weaker regions. During the first stage expansion, the weaker region expands moving the anchors laterally apart. The anchors straddle the fibrous cap and embed into the vessel wall. The second stage expansion of the stent exerts gentler stresses by the weaker region against the fibrous cap while the stronger region exerts greater stresses on the remainder of the vessel wall to open the vessel.
    Type: Application
    Filed: June 28, 2013
    Publication date: October 31, 2013
    Inventors: Daniel L. Cox, Christopher Feezor
  • Patent number: 8556849
    Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.
    Type: Grant
    Filed: January 12, 2012
    Date of Patent: October 15, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Paul M. Consigny, William E. Webler, Gustavo D. Cipolla, Gordon Steward, Benny Serna, Daniel L. Cox
  • Publication number: 20130261723
    Abstract: Embodiments of the present invention include methods for the treatment, prevention, or amelioration of vascular disease and/or disorder in diabetic patients. The methods include implantation of a stent including a drug, and the use of a drug coated balloon. The DES may be a DES having a metal body and a coating including the drug, or a bioabsorbable stent with drug in the body of the stent, in a coating on the stent, or both in the body of the stent and in a coating on the stent.
    Type: Application
    Filed: March 30, 2012
    Publication date: October 3, 2013
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: John J. Stankus, Syed F.A. Hossainy, Daniel L. Cox, Paul M. Consigny
  • Publication number: 20130218131
    Abstract: A catheter configured for delivering an agent to a patient's vessel wall is described. The catheter includes an inflatable balloon substantially covered by a expandable cage such that when the inflatable balloon is inflated the expandable cage substantially surrounds an outer surface of the inflated balloon. The inflatable balloon is configured to be deployed within a lumen against a lumen wall and separated from the lumen wall by the expandable cage in an expanded state, and is adapted to provide an agent delivery to a treatment site, and the expandable cage is further collapsible and is removable from said lumen.
    Type: Application
    Filed: February 7, 2013
    Publication date: August 22, 2013
    Inventor: Daniel L. Cox
  • Publication number: 20130218077
    Abstract: A catheter configured for delivering an agent to a patient's vessel wall is described. The catheter includes an inflatable balloon substantially covered by a expandable cage such that when the inflatable balloon is inflated the expandable cage substantially surrounds an outer surface of the inflated balloon. The inflatable balloon is configured to be deployed within a lumen against a lumen wall and separated from the lumen wall by the expandable cage in an expanded state, and is adapted to provide an agent delivery to a treatment site, and the expandable cage is further collapsible and is removable from said lumen.
    Type: Application
    Filed: February 7, 2013
    Publication date: August 22, 2013
    Inventor: Daniel L. Cox
  • Patent number: 8486012
    Abstract: Embodiments of a method and apparatus to prevent reperfusion injury. In one embodiment, blood flow proximal to a lesion is occluded. An infusion catheter is advanced to a region distal to the lesion and an anti-reperfusion injury drug is delivered. The lesion may then be treated with a dilating device to reintroduce blood flow to the region distal to the lesion.
    Type: Grant
    Filed: August 9, 2012
    Date of Patent: July 16, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Daniel L. Cox, Hongzhi Bai, Paul Consigny, Jessica G. Chiu
  • Patent number: 8475518
    Abstract: A stent for implantation in a body lumen for protecting from rupture a fibrous cap in order to treat vulnerable plaque. One embodiment of the stent achieves staged expansion through stronger and weaker circumferential regions, and includes optional anchors positioned at the circumferential transition between the stronger and weaker regions. During the first stage expansion, the weaker region expands moving the anchors laterally apart. The anchors straddle the fibrous cap and embed into the vessel wall. The second stage expansion of the stent exerts gentler stresses by the weaker region against the fibrous cap while the stronger region exerts greater stresses on the remainder of the vessel wall to open the vessel.
    Type: Grant
    Filed: July 11, 2007
    Date of Patent: July 2, 2013
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Daniel L. Cox, Christopher Feezor
  • Patent number: 8388573
    Abstract: A catheter configured for delivering an agent to a patient's vessel wall is described. The catheter includes an inflatable balloon substantially covered by a expandable cage such that when the inflatable balloon is inflated the expandable cage substantially surrounds an outer surface of the inflated balloon. The inflatable balloon is configured to be deployed within a lumen against a lumen wall and separated from the lumen wall by the expandable cage in an expanded state, and is adapted to provide an agent delivery to a treatment site, and the expandable cage is further collapsible and is removable from said lumen.
    Type: Grant
    Filed: June 28, 2006
    Date of Patent: March 5, 2013
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Daniel L. Cox