Patents by Inventor Daniel L. Cox
Daniel L. Cox has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8486012Abstract: Embodiments of a method and apparatus to prevent reperfusion injury. In one embodiment, blood flow proximal to a lesion is occluded. An infusion catheter is advanced to a region distal to the lesion and an anti-reperfusion injury drug is delivered. The lesion may then be treated with a dilating device to reintroduce blood flow to the region distal to the lesion.Type: GrantFiled: August 9, 2012Date of Patent: July 16, 2013Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Daniel L. Cox, Hongzhi Bai, Paul Consigny, Jessica G. Chiu
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Patent number: 8475518Abstract: A stent for implantation in a body lumen for protecting from rupture a fibrous cap in order to treat vulnerable plaque. One embodiment of the stent achieves staged expansion through stronger and weaker circumferential regions, and includes optional anchors positioned at the circumferential transition between the stronger and weaker regions. During the first stage expansion, the weaker region expands moving the anchors laterally apart. The anchors straddle the fibrous cap and embed into the vessel wall. The second stage expansion of the stent exerts gentler stresses by the weaker region against the fibrous cap while the stronger region exerts greater stresses on the remainder of the vessel wall to open the vessel.Type: GrantFiled: July 11, 2007Date of Patent: July 2, 2013Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Daniel L. Cox, Christopher Feezor
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Patent number: 8388573Abstract: A catheter configured for delivering an agent to a patient's vessel wall is described. The catheter includes an inflatable balloon substantially covered by a expandable cage such that when the inflatable balloon is inflated the expandable cage substantially surrounds an outer surface of the inflated balloon. The inflatable balloon is configured to be deployed within a lumen against a lumen wall and separated from the lumen wall by the expandable cage in an expanded state, and is adapted to provide an agent delivery to a treatment site, and the expandable cage is further collapsible and is removable from said lumen.Type: GrantFiled: June 28, 2006Date of Patent: March 5, 2013Assignee: Abbott Cardiovascular Systems Inc.Inventor: Daniel L. Cox
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Publication number: 20120296313Abstract: Introducer sheath for use in inserting a balloon catheter into a patient's vasculature includes a tubular member having an inner diameter, an outer diameter, a proximal end, a distal end, and a length therebetween, the inner diameter being sized to receive a catheter shaft having an attached expandable member in a deflated condition. The inner diameter can be varied from a first inner diameter at the proximal end and a second inner diameter at the distal end, the first inner diameter being greater than the second inner diameter. A method of inserting a balloon catheter into the vasculature of a patient is also disclosed. Additionally, a balloon catheter kit including a catheter and an introducer sheath is disclosed.Type: ApplicationFiled: May 20, 2011Publication date: November 22, 2012Applicant: Abbott Cardiovascular Systems Inc.Inventors: Anthony S. Andreacchi, Daniel L. Cox
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Patent number: 8262612Abstract: Embodiments of a method and apparatus to prevent reperfusion injury. In one embodiment, blood flow proximal to a lesion is occluded. An infusion catheter is advanced to a region distal to the lesion and an anti-reperfusion injury drug is delivered. The lesion may then be treated with a dilating device to reintroduce blood flow to the region distal to the lesion.Type: GrantFiled: November 10, 2010Date of Patent: September 11, 2012Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Daniel L. Cox, Hongzhi Bai, Paul Consigny, Jessica G. Chiu
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Patent number: 8241348Abstract: An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen for rupturing a fibrous cap to controllably release vulnerable plaque. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by links. The stent includes struts and links of varying strengths about the circumference of the stent. The weaker struts and links require less force to open and, hence, may apply more stress to rupture the fibrous cap while the stronger struts and links protect the healthy portions of the body lumen. In another embodiment, the stent may include stress concentrators positioned on outer surfaces of the links. The stress concentrators are aligned with the fibrous cap prior to stent expansion so that upon stent expansion, the stress concentrators induce stress to rupture the fibrous cap, thereby releasing the vulnerable plaque.Type: GrantFiled: March 22, 2010Date of Patent: August 14, 2012Assignee: Abbott Cardiovascular Systems Inc.Inventor: Daniel L. Cox
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Patent number: 8187324Abstract: A medical device that can be used for treating a defective heart valve. One aspect of the invention pertains to a longitudinally adjustable medical device that comprises a distal portion, a proximal portion, and a cord member. The distal portion comprises a distal anchoring member, a distal telescope, and a distal backbone. The proximal portion comprises a proximal anchoring member, a proximal telescope, and a proximal backbone. The distal backbone and the proximal backbone are configured to provide a structural support to the device while providing flexibility to the device. The cord member is disposed within the device and used to facilitate longitudinal adjustment for the device.Type: GrantFiled: June 1, 2006Date of Patent: May 29, 2012Assignee: Advanced Cardiovascular Systems, Inc.Inventors: William E. Webler, Daniel L. Cox, Richard Newhauser
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Publication number: 20120108959Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.Type: ApplicationFiled: January 12, 2012Publication date: May 3, 2012Applicant: Abbott Cardiovascular Systems Inc.Inventors: Paul M. Consigny, William E. Webler, Gustavo D. Cipolla, Gordon Stewart, Benny Serna, Daniel L. Cox
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Patent number: 8100855Abstract: Systems, devices and methods for eluting an agent at a treatment site are disclosed. The devices include an expandable frame and at least one membrane. The membrane may carry an agent to elute at the treatment site. The membrane may allow blood flow at the treatment site during agent delivery.Type: GrantFiled: September 17, 2007Date of Patent: January 24, 2012Assignee: Abbott Cardiovascular Systems, Inc.Inventors: Paul M. Consigny, William E. Webler, Gustavo D. Cipolla, Gordon Stewart, Benny Serna, Daniel L. Cox
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Patent number: 8057529Abstract: A stent delivery system for implantation of a stent in a vessel includes an outer tubular member having a restraining sheath and an inner tubular member having a distal end which has a compressed stent mounted thereto. The proximal end of the inner tubular member is connected to a housing assembly which prevents the inner tubular member from moving when the outer tubular member is retracted to deploy the stent. The proximal end of the outer tubular member is attached to a pull-back handle which is slidably mounted on the base of the housing assembly. When the pull-back handle is retracted, the restraining sheath is retracted to deploy the sheath, while the inner tubular member remains stationary.Type: GrantFiled: September 25, 2008Date of Patent: November 15, 2011Assignee: Abbott Cardiovascular Systems Inc.Inventors: Daniel L. Cox, Mathew J. Fitz, William J. Harrison, Michael D. Schultz, Josepher A. Ventura
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Patent number: 8052701Abstract: Methods and apparatuses for treating a vulnerable plaque are described herein. In one aspect of the invention, the exemplary apparatus includes a medical device to treat a vulnerable plaque within a body lumen, where the medical device is adapted to position a rupturing device to rupture a fibrous cap of a vulnerable plaque. In one particular embodiment, the medical device includes a rupturing wire having a predetermined pattern to enable the rupturing device to rupture the fibrous cap of the vulnerable plaque. Other methods and apparatuses are also described.Type: GrantFiled: June 2, 2003Date of Patent: November 8, 2011Assignee: Abbott Cardiovascular Systems Inc.Inventors: Daniel L. Cox, Jeffrey Ellis, Timothy A. Limon
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Patent number: 8029558Abstract: An improved stent design and stent delivery catheter assembly for repairing a main vessel and a side branch vessel forming a bifurcation. The stent includes rings aligned along a common longitudinal axis and connected by links, where the stent has one or more portals for aligning with and partially expanding into the opening to the side branch vessel. The stent is implanted at a bifurcation so that the main stent section is in the main vessel, and the portal section covers at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel. Radiopaque markers on the stent and on the tip of the delivery catheter assist in aligning the portal section with the opening to the side branch vessel.Type: GrantFiled: July 7, 2006Date of Patent: October 4, 2011Assignee: Abbott Cardiovascular Systems, Inc.Inventors: Diem Uyen Ta, Caroline Wu, Brenna K. Hearn, Daniel L. Cox, Leonard D. Barbod, Jessie Delgado, Stephen Dirk Pacetti, Thomas Ray Hatten, David K. Wrolstad, Kenneth Kay Armstrong, Darrin J. Kent
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Publication number: 20110208286Abstract: An improved stent design and stent delivery catheter assembly for repairing a main vessel and a side branch vessel forming a bifurcation. The stent includes rings aligned along a common longitudinal axis and connected by links, where the stent has one or more portals for aligning with and partially expanding into the opening to the side branch vessel. The stent is implanted at a bifurcation so that the main stent section is in the main vessel, and the portal section covers at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel. Radiopaque markers on the stent and on the tip of the delivery catheter assist in aligning the portal section with the opening to the side branch vessel.Type: ApplicationFiled: May 2, 2011Publication date: August 25, 2011Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.Inventors: Diem Uyen Ta, Caroline Wu, Brenna K. Hearn, Daniel L. Cox, Leonardo D. Barbod, Jessie Delgado, Stephen Dirk Pacetti, Thomas Ray Hatten, David K. Wrolstad, Kenneth Kay Armstrong, Darrin J. Kent
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Patent number: 7959667Abstract: An improved stent design and stent delivery catheter assembly for repairing a main vessel and a side branch vessel forming a bifurcation. The stent includes rings aligned along a common longitudinal axis and connected by links, where the stent has one or more portals for aligning with and partially expanding into the opening to the side branch vessel. The stent is implanted at a bifurcation so that the main stent section is in the main vessel, and the portal section covers at least a portion of the opening to the side branch vessel. A second stent can be implanted in the side branch vessel and abut the expanded central section to provide full coverage of the bifurcated area in the main vessel and the side branch vessel. Radiopaque markers on the stent and on the tip of the delivery catheter assist in aligning the portal section with the opening to the side branch vessel.Type: GrantFiled: December 21, 2006Date of Patent: June 14, 2011Assignee: Abbott Cardiovascular Systems Inc.Inventors: Diem Uyen Ta, Caroline Wu, Brenna K. Hearn, Daniel L. Cox, Leonard D. Barbod, Jessie Delgado, Stephen Dirk Pacetti, Thomas Ray Hatten, David K. Wrolstad, Kenneth Kay Armstrong, Darrin J. Kent
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Patent number: 7918011Abstract: A radiopaque nitinol medical device such as a stent for use with or implantation in a body lumen is disclosed. The stent is made from a superelastic alloy such as nickel-titanium or nitinol, and includes a ternary element selected from the group of chemical elements consisting of iridium, platinum, gold, rhenium, tungsten, palladium, rhodium, tantalum, silver, ruthenium, or hafnium. The added ternary element improves the radiopacity of the nitinol stent comparable to that of a stainless steel stent of the same and strut pattern coated with a thin layer of gold. The nitinol stent has improved radioplacity yet retains its superelastic and shape memory behavior and further maintains a thin strut/wall thickness for high flexibility.Type: GrantFiled: October 10, 2007Date of Patent: April 5, 2011Assignee: Abbott Cardiovascular Systems, Inc.Inventors: John F. Boylan, Daniel L. Cox
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Patent number: 7914577Abstract: A medical device for treating a defective heart valve. The medical device comprises a delivery sheath and an implantable device moveably disposed within the delivery sheath. The implantable device further comprises a distal expandable basket, a proximal expandable basket, and a connecting member coupling at a first end to the distal expandable basket and at a second end to the proximal expandable basket. Each of the distal expandable basket and proximal expandable basket is in a collapsed state during delivery and an expanded state after deployment. An actuator is releasably coupled to the implantable device. When coupled to the implantable device, the actuator can move the implantable device in a way to allow for positioning of the distal and proximal expandable baskets.Type: GrantFiled: January 26, 2007Date of Patent: March 29, 2011Assignee: Advanced Cardiovascular Systems, Inc.Inventor: Daniel L. Cox
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Patent number: 7837650Abstract: Embodiments of a method and apparatus to prevent reperfusion injury. In one embodiment, blood flow proximal to a lesion is occluded. An infusion catheter is advanced to a region distal to the lesion and an anti-reperfusion injury drug is delivered. The lesion may then be treated with a dilating device to reintroduce blood flow to the region distal to the lesion.Type: GrantFiled: December 30, 2004Date of Patent: November 23, 2010Assignee: Advanced Cardiovascular Systems, Inc.Inventors: Daniel L. Cox, Hongzhi Bai, Paul Consigny, Jessica G. Chiu
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Publication number: 20100174303Abstract: An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen for rupturing a fibrous cap to controllably release vulnerable plaque. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by links. The stent includes struts and links of varying strengths about the circumference of the stent. The weaker struts and links require less force to open and, hence, may apply more stress to rupture the fibrous cap while the stronger struts and links protect the healthy portions of the body lumen. In another embodiment, the stent may include stress concentrators positioned on outer surfaces of the links. The stress concentrators are aligned with the fibrous cap prior to stent expansion so that upon stent expansion, the stress concentrators induce stress to rupture the fibrous cap, thereby releasing the vulnerable plaque.Type: ApplicationFiled: March 22, 2010Publication date: July 8, 2010Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.Inventor: Daniel L. Cox
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Patent number: 7731744Abstract: An expandable stent is implanted in a body lumen, such as a coronary artery, peripheral artery, or other body lumen for rupturing a fibrous cap to controllably release vulnerable plaque. The invention provides for a an intravascular stent having a plurality of cylindrical rings connected by links. The stent includes struts and links of varying strengths about the circumference of the stent. The weaker struts and links require less force to open and, hence, may apply more stress to rupture the fibrous cap while the stronger struts and links protect the healthy portions of the body lumen. In another embodiment, the stent may include stress concentrators positioned on outer surfaces of the links. The stress concentrators are aligned with the fibrous cap prior to stent expansion so that upon stent expansion, the stress concentrators induce stress to rupture the fibrous cap, thereby releasing the vulnerable plaque.Type: GrantFiled: October 25, 2002Date of Patent: June 8, 2010Assignee: Advanced Cariovascular Systems, Inc.Inventor: Daniel L. Cox
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Publication number: 20090098013Abstract: A radiopaque nitinol medical device such as a stent for use with or implantation in a body lumen is disclosed. The stent is made from a superelastic alloy such as nickel-titanium or nitinol, and includes a ternary element selected from the group of chemical elements consisting of iridium, platinum, gold, rhenium, tungsten, palladium, rhodium, tantalum, silver, ruthenium, or hafnium. The added ternary element improves the radiopacity of the nitinol stent comparable to that of a stainless steel stent of the same size and strut pattern coated with a thin layer of gold. The nitinol stent has improved radiopacity yet retains its superelastic and shape memory behavior and further maintains a thin strut/wall thickness for high flexibility.Type: ApplicationFiled: December 17, 2008Publication date: April 16, 2009Inventors: John F. Boylan, Daniel L. Cox