Abstract: An apparatus is provided which comprises one or more magnetoelectric spin orbit (MESO) minority gates with different peripheral complementary metal oxide semiconductor (CMOS) circuit techniques in the device layer including: (1) current mirroring, (2) complementary supply voltages, (3) asymmetrical transistor sizing, and (4) using transmission gates. These MESO minority gates use the multi-phase clock to prevent back propagation of current so that MESO gate can correctly process the input data.

Abstract: Drug infusion systems are disclosed including an infusion head configured to deliver a primary drug and a secondary drug to a patient's subcutaneous tissue. The secondary drug may be provided in a controlled-release material and/or a drug-containing reservoir. Methods for assembling and using such drug infusion systems are also disclosed. The secondary drug may extend the wear time of the drug infusion systems.

Abstract: An applicator assembly for use with a dmg infusion system having multiple wear configurations, including a tethered configuration and a patch configuration. The applicator assembly may be a multi-functional device configured to (1) selectively apply an infusion head and/or a holder to a patients skin and (2) insert an injection device of the infusion head into the patients skin. The drug infusion system may be worn interchangeably in the tethered configuration by placing a dmg delivery device in fluid communication with the infusion head via an intermediate tubing set, or in the patch configuration by coupling the drug delivery device to the holder and placing the dmg delivery device in fluid communication with the infusion head without the intermediate tubing set.

Abstract: Embodiments include a memory array and a method of forming the memory array. A memory array includes a first dielectric over first metal traces, where first metal traces extend along a first direction, second metal traces on the first dielectric, where second metal traces extend along a second direction perpendicular to the first direction, and third metal traces on the second dielectric, where third metal traces extend along the first direction. The memory array includes a ferroelectric capacitor positioned in a trench having sidewalls and bottom surface, where the trench has a depth defined from a top surface of first metal trace to the top surface of third metal trace. The memory array further includes an insulating sidewall, a first electrode, a ferroelectric, and a second electrode disposed in the trench, where the trench has a rectangular cylinder shape defined by the first, second, and third metal traces.

Abstract: Systems, methods, and apparatuses for improved retirement income plans are provided. A method includes determining that a user is a participant in a retirement income Collective Investment Trust (CIT); retrieving an age of the user; determining that the age of the user is less than a first predefined age, and investing a portion of the retirement income CIT in a Target-Date Fund (TDF); transferring a predetermined amount of the TDF into an asset preservation fund when the age of the user is greater than or equal to the first predefined age and less than a second predefined age; and, based on the user's age being greater than or equal to the second predefined age, (i) purchasing a Qualified Longevity Annuity Contract (QLAC) with funds from the asset preservation fund, and (ii) transferring a current balance of the TDF into a draw down fund.

Abstract: The present disclosure relates to drug-delivery apparatuses, and in particular, to a drug-delivery apparatus with a fluidic subsystem that can be used to deliver multiple injections to a patient from a drug container storing a drug fluid. The fluidic subsystem may include multiple injection-needle compartments and re-sealable septa to allow multiple accesses to the drug container, while also preserving the sterility of the drug fluid and of the fluid pathway through which the fluid is delivered to a patient. In some embodiments, the fluidic subsystem may be used to deliver drug fluids that do not contain any preservatives (e.g., non-preserved drugs).

Abstract: The present disclosure relates to a drug-delivery device that is attachable to an infusion set hub that has been pre-inserted into a patient's body. The pre-inserted infusion set hub may be configured to deliver a primary drug such as insulin or an insulin analog. The drug-delivery device may deliver a secondary drug such as a glucagon, an NS AID, or another type of insulin or insulin analog through a cannula of the infusion hub.

Abstract: An insulin infusion set (IIS) device with one or more features designed to achieve longevity in a patients continuous subcutaneous insulin infusion (CSII) site viability. One exemplary feature is an adsorbent material configured to adsorb phenolic excipients (e.g., m-cresol or other preservatives) from the insulin formulation. The adsorbent material may be positioned along a fluid pathway specifically designed to increase and/or extend exposure between the insulin formulation and the adsorbent material. Another exemplary feature is a medicament configured to reduce the patients inflammation or slow the progression of the patients inflammatory response. Yet another exemplary feature is a diffusive catheter configured to deliver the insulin formulation in a diffuse manner.

Abstract: Portable devices include environmental sensors that generate metrics about the environment (e.g., accelerometers detecting impulses and vibration, and GPS receivers detecting position and velocity). Such devices often use environmental metrics to extract user input directed at the device by the user, and status information about the device and the environment. Presented herein are techniques for using environmental metrics to infer physical activities performed by the user while attached to the device. For example, jogging may be inferred from regular, strong impulses and typical jogging speed; walking may be inferred from regular, weak impulses and typical walking speed; and riding in a vehicle may be inferred from low-level vibrations and high speed (optionally identifying the type of vehicle ridden by the user). Based on these inferences, the device may automatically present applications and/or or adjust user interfaces suitable for the user's physical activity, rather than responsive to user input.

Abstract: A roller device, including a first tube having a first diameter, and a through-bore having a second diameter smaller than the first diameter, the through-bore extending through and concentric with the first tube, a first rod having a third diameter smaller than the second diameter, a first end, and a second end, where the second end of the first rod is operatively arranged to telescopingly engage with the through-bore of the first tube, a second rod having a fourth diameter equal to the third diameter, a first end and a second end, where the first end of the second rod is operatively arranged to telescopingly engage with the through-bore of the first tube, at least one roller arranged to rotate about the first tube, and a first handle fixedly secured to the first end of the first rod.

Abstract: The present disclosure relates to a connector hub adapted for use with an infusion set. The connector hub has a first connector and a second connector. The first connector communicates with a first fluid channel and has a first interface. The second connector communicates with a second fluid channel and has a second interface. Attaching the first and second connectors engages the first and second interfaces and provides fluid communication between the first and second fluid channels. Fluid flows between the medication reservoir and a cannula through the first and second fluid channels. At least one of the connectors may include a repositionable pivot member defining an interface.

Abstract: A roller device, including a first tube having a first diameter, and a through-bore having a second diameter smaller than the first diameter, the through-bore extending through and concentric with the first tube, a first rod having a third diameter smaller than the second diameter, a first end, and a second end, where the second end of the first rod is operatively arranged to telescopingly engage with the through-bore of the first tube, a second rod having a fourth diameter equal to the third diameter, a first end and a second end, where the first end of the second rod is operatively arranged to telescopingly engage with the through-bore of the first tube, at least one roller arranged to rotate about the first tube, and a first handle fixedly secured to the first end of the first rod.

Abstract: A first data window of a pulse waveform signal comprising a first number of samples is analyzed to determine a level of confidence that a pulse sensing device is placed correctly. If an initial level of confidence is met, the user is given positive feedback, and a second data window of a pulse waveform signal comprising a second, larger number of samples is analyzed. If an increased level of confidence is met, the user is given increased positive feedback. If a level of confidence is not met, the user is given negative feedback. If a final level of confidence is met, the user is given feedback that the pulse sensing device is placed correctly.

Abstract: Tube management devices are disclosed for use with an infusion set having a flexible tube. An exemplary device includes a central spindle defining an axis, a base member, and an upper member. The base member and upper member may project radially outwardly from the central spindle and may be axially spaced apart. The device may include a plurality of retainer members disposed on at least one of the base member and the upper member. The central spindle, the base member, the upper member, and the plurality of retainer members define a toroidal space sized to receive a variable length of the flexible tube.

Abstract: Some embodiments include apparatuses having a first magnet, a first stack of layers coupled to a first portion of the first magnet, a first layer coupled to a second portion of the first magnet, a second magnet, a second stack of layers coupled to a first portion of the second magnet, a second layer coupled to a second portion of the second magnet, a conductor coupled to the first stack of layers and to the second layer, and a conductive path coupled to the first portion of the first magnet and to the first portion of the second magnet, each of the first and second layers including a magnetoelectric material, each of the first and second stacks of layers providing an inverse spin orbit coupling effect.

Abstract: A transparent tubing is provided comprising a longitudinal axis having a center; an inner circumferential surface defining a fluid pathway therethrough for delivering a first medium having a first index of refraction m; an outer circumferential surface; at least one visual marker; and, at least one integrated lens disposed opposite from the at least one visual marker, the at least one integrated lens configured to direct light from the at least one visual marker for detecting a presence or an absence in the fluid pathway of a second medium having a second index of refraction n2, where n2 is different from the first index of refraction n1. A method of making transparent tubing having at least one integrated lens is also provided.

Abstract: According to one aspect of the present disclosure, a method for estimating blood pressure is provided, comprising training a machine learning model on a cohort data set. The cohort data set may include subject-specific contextual data, time-varying features, and blood pressure measurements for a plurality of subjects. The method may include receiving contextual data for a specific subject, wherein the contextual data includes medical history data of the subject. The method may further include personalizing the machine learning model to the subject based on the contextual data. The method may include calibrating the machine learning model to the subject based on a set of time-varying features and blood pressure measurements of the subject. In addition, the method may include using the machine learning model and the time-varying features for the subject to generate a blood pressure estimate.

Abstract: A wrist-worn device heart-monitoring device is presented. The wrist-worn heart-monitoring device includes a radial tonometer configured to output a pressure signal indicating a pulse pressure wave at a user's wrist, two or more electrodes configured to output an electrical signal indicating a user's heart has been commanded to contract, and a microphone configured to output an audio signal indicating a closing of a user's aortic valve. The wrist-worn heart-monitoring device further includes a pulse transit time monitor configured to calculate a pre-ejection period of the user's heart based on at least the pressure, electrical, and audio signals, and calculate a pulse transit time based on at least the pre-ejection period, the pressure signal, and the electrical signal.

Abstract: Some embodiments include apparatuses having a first magnet, a first stack of layers coupled to a first portion of the first magnet, a first layer coupled to a second portion of the first magnet, a second magnet, a second stack of layers coupled to a first portion of the second magnet, a second layer coupled to a second portion of the second magnet, a conductor coupled to the first stack of layers and to the second layer, and a conductive path coupled to the first portion of the first magnet and to the first portion of the second magnet, each of the first and second layers including a magnetoelectric material, each of the first and second stacks of layers providing an inverse spin orbit coupling effect.

Abstract: An apparatus is provided which comprises a full adder including magnetoelectric material and spin orbit material. In some embodiments, the adder includes: a 3-bit carry generation structure and a multi-bit sum generation structure coupled to the 3-bit carry generation structure. In some embodiments, the 3-bit carry generation structure includes at least three cells comprising magnetoelectric material and spin orbit material, wherein the 3-bit carry generation structure is to perform a minority logic operation on first, second, and third inputs to generate a carry output. In some embodiments, the multi-bit sum generation structure includes at least four cells comprising magnetoelectric material and spin orbit material, wherein the multi-bit sum generation structure is to perform a minority logic operation on the first, second, and third inputs and the carry output to generate a sum output.