Abstract: The invention provides compounds of Formula (I): as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.

Abstract: The invention provides compounds of Formula (I): as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.

Abstract: Described herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.

Abstract: This disclosure provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.

Abstract: The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

Abstract: The invention provides compounds of Formula (1): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

Abstract: This disclosure provides compounds of Formula (I) as described herein, along with pharmaceutically acceptable salts, pharmaceutical compositions containing such compounds, and methods to use these compounds, salts and compositions for treating viral infections.

Abstract: The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

Abstract: A protective case for a mobile electronic device having a touchscreen constructed from at least two separate frame components is disclosed herein. The frame components include a back frame and a front frame or cover. In some embodiments, when a mobile electronic device is held within the back frame, a stretchable cover is stretched over the back frame and device to securely hold the device within the back frame. The front frame or cover includes a touchscreen cover. The front frame or cover is removably coupled to the back frame with grasping protrusions or engagement members that engage with corresponding components of the back frame.

Abstract: Disclosed herein are pyrazole pyrimidine compounds that modulate and/or inhibit hematopoietic progenitor kinase 1, as well as methods of making such compounds and therapeutic methods of using same.

Abstract: The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

Abstract: The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

Abstract: The invention provides compounds of Formula (I): as further described herein, as well as pharmaceutical compositions comprising such compounds, and methods to use the compounds and pharmaceutical compositions for treatment of certain viral disorders, including influenza.

Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.

Abstract: Disclosed herein are pyrazole pyrimidine compounds that modulate and/or inhibit hematopoietic progenitor kinase 1, as well as methods of making such compounds and therapeutic methods of using same.

Abstract: A protective case for a mobile electronic device is disclosed herein. The protective case includes a front portion and a back portion that is configured to slide into a side of the front portion to effectuate the sealing and closure of the case. The front portion is configured to cover the front face and sides of the device and includes rails or protrusions on opposing sides of its internal surface. The back portion is configured to cover the back side of the device and includes channels on opposing sides that are configured to be slid along the rails on the opposing sides of the internal surface of the front component arid thereby open and close the case. The protective case is configured to be reversibly attached to a stand that facilitates multiple viewing/operating positions.

Abstract: A protective case for a mobile electronic device having a touchscreen constructed from at least two separate frame components is disclosed herein. The frame components include a back frame and a front frame or cover. In some embodiments, when a mobile electronic device is held within the back frame, a stretchable cover is stretched over the back frame and device to securely hold the device within the back frame. The front frame or cover includes a touchscreen cover. The front frame or cover is removably coupled to the back frame with grasping protrusions or engagement members that engage with corresponding components of the back frame.

Abstract: A protective case for a mobile device that includes a back frame and a front cover is disclosed herein. The back frame has a rigid plastic back frame with are elastomeric material bonded to portions of the plastic frame. An elastomeric insert is positioned around a portion of the interior perimeter of the back frame to provide impact resistance. Back frame engagement members are positioned on the perimeter of the rigid plastic back frame. The front cover mates with the back frame to enclose the elastomeric insert and the device. The front cover includes a touch screen cover and a rigid plastic front frame bonded to a perimeter of the touch screen cover. Front cover engagement members extend from the rigid plastic front frame that engage the back frame engagement members to bold the front cover on the back frame and enclose the device.

Abstract: A protective case for a portable device having a touchscreen constructed from a back frame, a front frame, and a stretchable cover is disclosed herein. The back frame receives the device through an open front and the stretchable cover is stretched over the back frame and the device. A portion of the cover stretches over the back frame and device such that the device is securely held in the back frame. A front frame with a transparent screen protector that allows the touch screen of the device to be used while the device is fully enclosed in the case is removably coupled to the back frame with grasping protrusions that connect to mounting portions on the back frame that extend through openings in the stretchable cover.

Abstract: The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.