Patents by Inventor Daniel Solomon
Daniel Solomon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240046860Abstract: A method can include determining that a first frame for display on an emissive display meets a low encoded intensity condition; based on the determination that the first frame meets the low encoded intensity condition, disabling refresh rate transitions when displaying multiple frames on the emissive display; while the refresh rate transitions are disabled, maintaining a refresh rate while changing a graphic intensity; determining that a second frame does not meet the low encoded intensity condition; based on the determination that the second frame does not meet the low encoded intensity condition, enabling refresh rate transitions when displaying multiple frames on the emissive display; and while the refresh rate transitions are enabled, changing the refresh rate for the emissive display based on the graphic intensity changing.Type: ApplicationFiled: May 10, 2021Publication date: February 8, 2024Inventors: Sangmoo CHOI, Daniel SOLOMON
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Patent number: 11854457Abstract: A method includes: (a) receiving initial image frame data to display an image frame on a display panel, a luminance of each pixel of the display corresponding to a gray level; (b) identifying dark pixels at or below a first threshold gray level; (c) identifying pixels to be modified as a subset of the dark pixels neighbored by at least one bright pixel exceeding a second threshold gray level; (d) increasing by an incremental amount the gray level of the pixels to be modified, providing modified image frame data composed of: (i) the dark pixels that are neighbored by at least one bright pixel having gray levels that have been increased by the incremental gray level amount, and (ii) other pixels that have gray levels from the initial image frame data; and (e) displaying the image frame using the modified image frame data.Type: GrantFiled: July 30, 2021Date of Patent: December 26, 2023Assignee: Google LLCInventors: Sangmoo Choi, Daniel Solomon
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Publication number: 20230398193Abstract: The disclosure provides, in various embodiments, polypeptides that upon administration to a mammalian subject, elicit a reduced immunogenicity in the subject, relative to a bacterial asparaginase. The disclosure also provides, in various embodiments, fusion proteins comprising one or more of the polypeptides, polynucleotides encoding the polypeptides, vectors and host cells suitable for expressing the polypeptides, methods for treating a disease (e.g., cancer) in mammalian subject (e.g., a human), and methods for reducing a level of asparagine or asparagine-containing product in a biological fluid from a mammalian subject.Type: ApplicationFiled: October 19, 2021Publication date: December 14, 2023Inventors: Meghan Whitney FRANKLIN, Gevorg GRIGORYAN, Daniel Solomon LEVENTHAL
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Publication number: 20230298505Abstract: A method includes: (a) receiving initial image frame data to display an image frame on a display panel, a luminance of each pixel of the display corresponding to a gray level; (b) identifying dark pixels at or below a first threshold gray level; (c) identifying pixels to be modified as a subset of the dark pixels neighbored by at least one bright pixel exceeding a second threshold gray level; (d) increasing by an incremental amount the gray level of the pixels to be modified, providing modified image frame data composed of: (i) the dark pixels that are neighbored by at least one bright pixel having gray levels that have been increased by the incremental gray level amount, and (ii) other pixels that have gray levels from the initial image frame data; and (e) displaying the image frame using the modified image frame data.Type: ApplicationFiled: July 30, 2021Publication date: September 21, 2023Inventors: Sangmoo Choi, Daniel Solomon
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Patent number: 11749145Abstract: This document describes techniques and apparatuses for performing color calibration of display modules using a reduced number of display characteristic measurements. In aspects, methods include generating a measured lookup table (50) for a source display module (32), using dynamic optimization to down-sample the measured lookup table and select a set of color patches, sending the color patches to a testing display module; measuring output values for the testing display module; generating a sparse lookup table (52) relating the color patches and the measured output values, up-sampling the sparse lookup table to a forward lookup table (54), and inverting the forward lookup table to generate a reverse lookup table (56). The reverse lookup table (56) can be utilized to determine correct output values (29) for driving a target display module to generate color lights within a display module color gamut.Type: GrantFiled: December 11, 2019Date of Patent: September 5, 2023Assignee: Google LLCInventors: Farnaz Agahian, Daniel Solomon
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Patent number: 11688367Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for enabling a variable refresh rate on a display. One of the methods includes receiving, from a content presentation device, a first signal set to a first value; completing generation of first visual content; and after completing the generation of the first visual content, determining that the first signal is set to the first value and a second threshold duration of time has not expired; sending, to the content presentation device, the first visual content, wherein sending the first visual content causes the content presentation device to change the first signal from the first value to the second value; and after sending the first visual content, receiving, from the content presentation device, the first signal set to the second value.Type: GrantFiled: July 19, 2021Date of Patent: June 27, 2023Assignee: Google LLCInventors: Wonjae Choi, Daniel Solomon, John Kaehler
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Patent number: 11536707Abstract: Systems, methods, and devices for analyzing small volumes of fluidic samples, as a non-limiting example, less than twenty microliters are provided. The devices are configured to make a first sample reading, for example, measure an energy property of the fluid sample, for example, osmolality, make a second sample reading, for example, detecting the presence or concentration of one or more analytes in the fluid sample, or make both the first sample reading and the second sample reading, for example, measuring the energy property of the fluid sample as well as detecting the presence or concentration of one or more analytes in the fluid sample.Type: GrantFiled: September 23, 2015Date of Patent: December 27, 2022Assignee: TEARLAB RESEARCH, INC.Inventors: Benjamin Sullivan, Steve Zmina, Melissa Lee, Brandon Westerberg, Matthew Daniel Solomon, Christian Potzner, Sebastiaan Garst, Matthew Springer, Jason Hayes, Peter Munster, Erol Craig Harvey, Michael Wilkinson, Joanna Slowinska, Derek Lee, Peter Van Ruijven
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Publication number: 20220223076Abstract: This document describes techniques and apparatuses for performing color calibration of display modules using a reduced number of display characteristic measurements. In aspects, methods include generating a measured lookup table (50) for a source display module (32), using dynamic optimization to down-sample the measured lookup table and select a set of color patches, sending the color patches to a testing display module; measuring output values for the testing display module; generating a sparse lookup table (52) relating the color patches and the measured output values, up-sampling the sparse lookup table to a forward lookup table (54), and inverting the forward lookup table to generate a reverse lookup table (56). The reverse lookup table (56) can be utilized to determine correct output values (29) for driving a target display module to generate color lights within a display module color gamut.Type: ApplicationFiled: December 11, 2019Publication date: July 14, 2022Applicant: Google LLCInventors: Farnaz Agahian, Daniel Solomon
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Publication number: 20220127326Abstract: The present invention relates in general to therapeutic fusion proteins useful to treat lysosomal storage diseases and methods for treating such diseases. Exemplary therapeutic fusion proteins comprise a lysosomal enzyme, a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide. Also provided are compositions and methods for treating Mucopolysaccharidosis Type IIIB (Sanfilippo B Syndrome), comprising a targeted therapeutic fusion protein comprising alpha-N-acetylglucosaminidase (Naglu), a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide.Type: ApplicationFiled: January 10, 2022Publication date: April 28, 2022Inventors: Mika Aoyagi-Scharber, Teresa Margaret Christianson, Melita Dvorak-Ewell, Daniel J. Wendt, Shinong Long, Jonathan LeBowitz, Daniel Solomon Gold
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Publication number: 20220064627Abstract: The present disclosure relates to a microfluidic device for the separation of metaphase chromosomes such that individual metaphase chromosomes may be dispensed discretely from the device. The microfluidic device comprises a flow channel including a series of expanded regions and constrictions. The present disclosure also relates to methods of separating metaphase chromosomes.Type: ApplicationFiled: January 23, 2020Publication date: March 3, 2022Inventors: Matthew Daniel Solomon, Richard Walter Doumani
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Patent number: 11254725Abstract: The present invention relates in general to therapeutic fusion proteins useful to treat lysosomal storage diseases and methods for treating such diseases. Exemplary therapeutic fusion proteins comprise a lysosomal enzyme, a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide. Also provided are compositions and methods for treating Mucopolysaccharidosis Type IIIB (Sanfilippo B Syndrome), comprising a targeted therapeutic fusion protein comprising alpha-N-acetylglucosaminidase (Naglu), a lysosomal targeting moiety, e.g., an IGF-II peptide, and a spacer peptide.Type: GrantFiled: April 8, 2019Date of Patent: February 22, 2022Assignee: BIOMARIN PHARMACEUTICAL INC.Inventors: Mika Aoyagi-Scharber, Teresa Margaret Christianson, Melita Dvorak-Ewell, Daniel J. Wendt, Shinong Long, Jonathan LeBowitz, Daniel Solomon Gold
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Publication number: 20210350771Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for enabling a variable refresh rate on a display. One of the methods includes receiving, from a content presentation device, a first signal set to a first value; completing generation of first visual content; and after completing the generation of the first visual content, determining that the first signal is set to the first value and a second threshold duration of time has not expired; sending, to the content presentation device, the first visual content, wherein sending the first visual content causes the content presentation device to change the first signal from the first value to the second value; and after sending the first visual content, receiving, from the content presentation device, the first signal set to the second value.Type: ApplicationFiled: July 19, 2021Publication date: November 11, 2021Inventors: Wonjae Choi, Daniel Solomon, John Kaehler
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Patent number: 11094296Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for enabling a variable refresh rate on a display. One of the methods includes receiving, from a content presentation device, a first signal set to a first value; completing generation of first visual content; and after completing the generation of the first visual content, determining that the first signal is set to the first value and a second threshold duration of time has not expired; sending, to the content presentation device, the first visual content, wherein sending the first visual content causes the content presentation device to change the first signal from the first value to the second value; and after sending the first visual content, receiving, from the content presentation device, the first signal set to the second value.Type: GrantFiled: August 20, 2019Date of Patent: August 17, 2021Assignee: Google LLCInventors: Wonjae Choi, Daniel Solomon, John Kaehler
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Patent number: 11060127Abstract: An assembly for preparing a specimen is provided that may be configured to determine the presence of at least one microorganism specie in the specimen. The assembly may include a pipette configured to acquire a specimen from a sample and an imaging cartridge configured to be in fluid communication with the pipette. The imaging cartridge and the pipette may be configured to be irreversibly coupled such that the specimen is bio-contained within the imaging cartridge and the pipette when the imaging cartridge and pipette are coupled together. Associated methods of use are also provided.Type: GrantFiled: March 7, 2019Date of Patent: July 13, 2021Assignee: BECTON, DICKINSON AND COMPANYInventors: Alexander George Lastovich, Anita Quinn, Pauline Elizabeth Bell, James Lee Schram, Rex Young Nielson, Jason Paul Hayes, Matthew James Springer, Lincoln Belcourt, Matthew Daniel Solomon
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Patent number: 10988722Abstract: The invention relates to a perfusion manifold assembly that allows for perfusion of a microfluidic device, such as an organ on a chip microfluidic device comprising cells that mimic cells in an organ in the body, that is detachably linked with an assembly so that fluid enters ports of the microfluidic device from a fluid reservoir, optionally without tubing, at a controllable flow rate.Type: GrantFiled: December 19, 2018Date of Patent: April 27, 2021Assignee: EMULATE, Inc.Inventors: Daniel Levner, Josiah Daniel Sliz, Christopher David Hinojosa, Guy Robert Thompson, II, Petrus Wilhelmus Martinus van Ruijven, Matthew Daniel Solomon, Christian Alexander Potzner, Patrick Sean Tuohy, Joshua Gomes, Norman Wen, Jacob Freake, Doug Sabin
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Publication number: 20210016281Abstract: A fluid device includes a base material including a flow path through which a solution flows and a first facing surface, a treatment substrate including a second facing surface which faces the first facing surface and in which a treatment unit which comes in contact with the solution and treats the solution is provided, and a sealing portion sandwiched between the first facing surface and the second facing surface, in which a treatment space surrounding the treatment unit with the sealing portion when viewed from a plate thickness direction and connected to the flow path is provided between the treatment substrate and the base material.Type: ApplicationFiled: March 19, 2019Publication date: January 21, 2021Inventors: Naoya ISHIZAWA, Ryo KOBAYASHI, Taro UENO, Tetsuomi TAKASAKI, Ronald Adam SEGER, Matthew Daniel SOLOMON, Alexei KOIFMAN
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Patent number: 10689608Abstract: Drop-to-drop connection schemes are described for putting a microfluidic device in fluidic communication with a fluid source or another microfluidic device, including but not limited to, putting a microfluidic device in fluidic communication with the perfusion manifold assembly.Type: GrantFiled: August 22, 2018Date of Patent: June 23, 2020Assignee: EMULATE, INC.Inventors: Daniel Levner, Josiah Daniel Sliz, Christopher David Hinojosa, Guy Robert Thompson, II, Petrus Wilhelmus Martinus van Ruijven, Matthew Daniel Solomon, Christian Alexander Potzner, Patrick Sean Tuohy
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Publication number: 20200184934Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for enabling a variable refresh rate on a display. One of the methods includes receiving, from a content presentation device, a first signal set to a first value; completing generation of first visual content; and after completing the generation of the first visual content, determining that the first signal is set to the first value and a second threshold duration of time has not expired; sending, to the content presentation device, the first visual content, wherein sending the first visual content causes the content presentation device to change the first signal from the first value to the second value; and after sending the first visual content, receiving, from the content presentation device, the first signal set to the second value.Type: ApplicationFiled: August 20, 2019Publication date: June 11, 2020Inventors: Wonjae Choi, Daniel Solomon, John Kaehler
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Publication number: 20190292759Abstract: The present invention provides an improved apparatus and method for removing clogs from a drain pipe. The apparatus includes a drain snake with a handle and barbs for snagging any material that is clogging the drain pipe. It also includes a protective cowl, constructed like a bellow, that includes a thumb ring, to completely cover the drain snake. The drain snake and the protective cowl are both made of a biodegradable material that will be innocuously being broken down over a period of time. Once the clogging material along with any residual material is removed, including any dirty liquids, along with the drain snake and the protective cowl are placed in a trash bin to biodegrade.Type: ApplicationFiled: March 26, 2018Publication date: September 26, 2019Inventors: ELIZABETH DANIELS SOLOMON PARKER, JOHN CHARLES BESS
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Publication number: 20190271023Abstract: An assembly for preparing a specimen is provided that may be configured to determine the presence of at least one microorganism specie in the specimen. The assembly may include a pipette configured to acquire a specimen from a sample and an imaging cartridge configured to be in fluid communication with the pipette. The imaging cartridge and the pipette may be configured to be irreversibly coupled such that the specimen is bio-contained within the imaging cartridge and the pipette when the imaging cartridge and pipette are coupled together. Associated methods of use are also provided.Type: ApplicationFiled: March 7, 2019Publication date: September 5, 2019Inventors: Alexander George Lastovich, Anita Quinn, Pauline Elizabeth Bell, James Lee Schram, Rex Young Nielson, Jason Paul Hayes, Matthew James Springer, Lincoln Belcourt, Matthew Daniel Solomon