Abstract: Disclosed are systems, including client devices and servers, and methods for creating a collaborative virtual session between client devices, wherein each of the client devices is associable with a coupler agent for interfacing with a communicating entity (such as a person). A client device includes a processor and memory operable to: generate a locally instantiated virtual room; instantiate a virtual representation of a first entity associated with the client device in the locally instantiated virtual room; transmit metadata representative of the first entity to a second client device; receive metadata representative of a second entity associated with the second client device; and, instantiate a virtual representation of the second entity as a function of the received metadata, from a perspective of the first entity, in the locally instantiated virtual room. A server can be utilized to join the client devices in the collaborative virtual session and exchange the metadata.

Abstract: Described are systems and methods for determining session intent of a user. Different users can use a network-based application in many different ways based on, for example, the user's purpose for using the application, the device on which the user is executing the application, the user themselves, date, time, location, etc. Through the collection of user activities during a user session, the intent of a user session can be determined. Once determined, content provided through the application can be further personalized to correspond to the determined session intent.

Abstract: The invention provides siRNA compositions for inhibiting gene expression in targeted cells. A multi-targeting siR-NA-aptamer platform is provided that is efficiently delivered and is processed by cellular RNAi machinery to produce one, two or more siRNAs. Methods of using the multi-targeting siRNA-aptamer for selectively targeting cancer cells to downregulate the expression of multiple genes are also provided.

Abstract: The invention provides siRNA compositions for inhibiting gene expression in targeted cells.

Abstract: There is provided a method of assessing a characteristic of a plant (2), comprising: obtaining a training dataset, wherein the training dataset comprises first data characterising a first electrical signal obtained from a first plant during a first time period when a stressor is present in the first plant or a growth environment of the first plant, second data characterising a second electrical signal obtained from the first plant during a second time period when a stressor is not present in the first plant or the growth environment of the first plant, and third data indicative of a characteristic of the first plant during the first time period and a characteristic of the first plant during the second time period; training a machine learning model based upon the training dataset; obtaining a third electrical signal from a second plant; and assessing, using the trained machine learning model, a characteristic of the second plant based upon the third electrical signal.

Abstract: Methods and systems disclosed herein describe generating virtual backgrounds for video communications. A virtual background generator may monitor a user's calendar and/or inbox for meetings. The virtual background generator may analyze the context of calendar invites and/or scheduled meetings to generate one or more virtual backgrounds for a video conference. A first background may be displayed for the video conference. Additionally, the virtual background generator may update the virtual background based on an analysis of one or more topics being discussed during the video conference. Based on the analysis of the one or more topics being discussed, the virtual background generator may generate a second virtual background to replace the first virtual background.

Abstract: Methods and systems disclosed herein describe generating virtual backgrounds for video communications. A virtual background generator may monitor a user's calendar and/or inbox for meetings. The virtual background generator may analyze the context of calendar invites and/or scheduled meetings to generate one or more virtual backgrounds for a video conference. A first background may be displayed for the video conference. Additionally, the virtual background generator may update the virtual background based on an analysis of one or more topics being discussed during the video conference. Based on the analysis of the one or more topics being discussed, the virtual background generator may generate a second virtual background to replace the first virtual background.

Abstract: Methods and systems disclosed herein describe generating virtual backgrounds for video communications. A virtual background generator may monitor a user's calendar and/or inbox for meetings. The virtual background generator may analyze the context of calendar invites and/or scheduled meetings to generate one or more virtual backgrounds for a video conference. A first background may be displayed for the video conference. Additionally, the virtual background generator may update the virtual background based on an analysis of one or more topics being discussed during the video conference. Based on the analysis of the one or more topics being discussed, the virtual background generator may generate a second virtual background to replace the first virtual background.

Abstract: A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge has a liquid input port for introducing an input liquid into an internal gap of the cartridge, the input liquid providing for at least one droplet, directly or via a liquid separation process within the internal gap, and the internal gap having at least one hydrophobic surface, at least one processing zone for processing samples located in the processing zone, and a delivery zone for delivering the at least one droplet from the liquid input port to the at least one processing zone. The delivery zone is configured to provide a repeating pattern of interacting electrowetting force for simultaneously transporting the at least one droplet within the delivery zone.

Abstract: Methods and systems disclosed herein describe generating virtual backgrounds for video communications. A virtual background generator may monitor a user's calendar and/or inbox for meetings. The virtual background generator may analyze the context of calendar invites and/or scheduled meetings to generate one or more virtual backgrounds for a video conference. A first background may be displayed for the video conference. Additionally, the virtual background generator may update the virtual background based on an analysis of one or more topics being discussed during the video conference. Based on the analysis of the one or more topics being discussed, the virtual background generator may generate a second virtual background to replace the first virtual background.

Abstract: Methods and systems disclosed herein describe generating virtual backgrounds for video communications. A virtual background generator may monitor a user's calendar and/or inbox for meetings. The virtual background generator may analyze the context of calendar invites and/or scheduled meetings to generate one or more virtual backgrounds for a video conference. A first background may be displayed for the video conference. Additionally, the virtual background generator may update the virtual background based on an analysis of one or more topics being discussed during the video conference. Based on the analysis of the one or more topics being discussed, the virtual background generator may generate a second virtual background to replace the first virtual background.

Abstract: Methods and systems disclosed herein describe generating virtual backgrounds for video communications. A virtual background generator may monitor a user's calendar and/or inbox for meetings. The virtual background generator may analyze the context of calendar invites and/or scheduled meetings to generate one or more virtual backgrounds for a video conference. A first background may be displayed for the video conference. Additionally, the virtual background generator may update the virtual background based on an analysis of one or more topics being discussed during the video conference. Based on the analysis of the one or more topics being discussed, the virtual background generator may generate a second virtual background to replace the first virtual background.

Abstract: The disclosed technology includes systems and methods for automatically generating a dynamic system context diagram based on machine-readable code. A method can include receiving, at a rules engine, machine-readable code describing interactions among a plurality of applications in software architecture, evaluating, with the rules engine in communication with a system of record (SoR), compliance of the interactions among the plurality of applications according to the SoR, identifying, with the rules engine, and based on compliance evaluation, one or more dependencies among the plurality of applications, generating, with an output engine, a system context diagram image comprising a graphical representation of the plurality of applications with associated interactions and dependencies, and outputting, for display, the system context diagram image.

Abstract: Systems and methods for mechanically rotating an aircraft about its center-of-gravity (CG) are disclosed. The system can enable the rear, or main, landing gear to squat, while the nose landing gear raises to generate a positive angle of attack for the aircraft for takeoff or landing. The system can also enable the nose gear and main gear to return to a relatively level fuselage attitude for ground operations. The system can include one or more hydraulically linked hydraulic cylinders to control the overall height of the nose gear and the main gear. Because the hydraulic cylinders are linked, a change on the length of the nose cylinder generates a proportional, and opposite, change in the length of the main cylinder, and vice-versa. A method and control system for monitoring and controlling the relative positions of the nose gear and main gear is also disclosed.

Abstract: The disclosed technology includes systems and methods for automatically generating a dynamic system context diagram based on machine-readable code. A method can include receiving, at a rules engine, machine-readable code describing interactions among a plurality of applications in software architecture, evaluating, with the rules engine in communication with a system of record (SoR), compliance of the interactions among the plurality of applications according to the SoR, identifying, with the rules engine, and based on compliance evaluation, one or more dependencies among the plurality of applications, generating, with an output engine, a system context diagram image comprising a graphical representation of the plurality of applications with associated interactions and dependencies, and outputting, for display, the system context diagram image.

Abstract: A coupled landing gear apparatus for an aircraft including at least a nose gear disposed forward of a neutral point of an aircraft by a first distance and at least a main gear disposed aft of the neutral point of the aircraft by a second distance. The at least a nose gear and the at least a main gear are in communication with one another.

Abstract: The disclosed technology includes systems and methods for automatically generating a dynamic system context diagram based on machine-readable code. A method can include receiving, at a rules engine, machine-readable code describing interactions among a plurality of applications in software architecture, evaluating, with the rules engine in communication with a system of record (SoR), compliance of the interactions among the plurality of applications according to the SoR, identifying, with the rules engine, and based on compliance evaluation, one or more dependencies among the plurality of applications, generating, with an output engine, a system context diagram image comprising a graphical representation of the plurality of applications with associated interactions and dependencies, and outputting, for display, the system context diagram image.

Abstract: A cartridge, in particular a disposable cartridge, for use in an electrowetting sample processing system. The cartridge has a liquid input port for introducing an input liquid into an internal gap of the cartridge, the input liquid providing for at least one droplet, directly or via a liquid separation process within the internal gap, and the internal gap having at least one hydrophobic surface, at least one processing zone for processing samples located in the processing zone, and a delivery zone for delivering the at least one droplet from the liquid input port to the at least one processing zone. The delivery zone is configured to provide a repeating pattern of interacting electrowetting force for simultaneously transporting the at least one droplet within the delivery zone.

Abstract: Digital microfluidics system with electrodes attached to a PCB has control unit for manipulating liquid droplets by electrowetting, cartridge accommodation site for taking up a disposable cartridge having a working gap in-between two hydrophobic surfaces, and magnetic conduit/backing combination. A barrier element on an individual electrode of the PCB for narrowing the working gap. A disposable cartridge is positioned at the cartridge accommodation site, its flexible working film touching there and of the barrier element an uppermost surface. In the working gap and above a path of selected electrodes a liquid portion or liquid droplet with magnetically responsive beads moves by electrowetting on the electrode path until a magnetic field of the magnetic conduit is reached. The backing magnet is activated before and during the moving to thereby attract and remove magnetically responsive beads therefrom.

Abstract: There is provided a method of assessing a characteristic of a plant (2), comprising: obtaining a training dataset, wherein the training dataset comprises first data characterising a first electrical signal obtained from a first plant during a first time period when a stressor is present in the first plant or a growth environment of the first plant, second data characterising a second electrical signal obtained from the first plant during a second time period when a stressor is not present in the first plant or the growth environment of the first plant, and third data indicative of a characteristic of the first plant during the first time period and a characteristic of the first plant during the second time period; training a machine learning model based upon the training dataset; obtaining a third electrical signal from a second plant; and assessing, using the trained machine learning model, a characteristic of the second plant based upon the third electrical signal.