Abstract: The present invention relates to novel methods for the isolation and the selective ex vivo expansion of V?2? TCR??+T cells and to their clinical application.

Abstract: A method of compositing a zooming user interface (ZUI) scene and a physical scene on a screen display is provided including: displaying on a display screen, ZUI motion picture images that show panning and zooming transitions within a ZUI presentation between a sequence of pauses at a sequence of target display elements within the ZUI presentation; displaying on the display screen physical scene motion picture images; prioritizing display of ZUI display elements at a location within an offset region; and prioritizing physical scene images at a location within a priority region.

Abstract: A method of compositing a zooming user interface (ZUI) scene and a physical scene on a screen display is provided including: displaying on a display screen, ZUI motion picture images that show panning and zooming transitions within a ZUI presentation between a sequence of pauses at a sequence of target display elements within the ZUI presentation; displaying on the display screen physical scene motion picture images; prioritizing display of ZUI display elements at a location within an offset region; and prioritizing physical scene images at a location within a priority region.

Abstract: A method for thermoforming synthetic paper is provided, more concretely for thermoforming holding strips of synthetic paper, the strips being used to produce sheet-holding devices of a specific configuration. The devices can be used in the assembly of sheet holders such as calendars, white sheet dispensers or information cards.

Abstract: The present invention relates to novel methods for the isolation and the selective ex vivo expansion of V?2? TCR??+T cells and to their clinical application.

Abstract: The present invention relates to a cell line of lymphocytes comprising ?? T cells, composition and production method thereof, and medical use namely for the use in medicine, namely in cancer immunotherapy. The cell line comprise a sample of human peripheral blood V?1+ ?? T cells expressing functional natural cytotoxicity receptors (NCRs). These V?1+ NCR+ T lymphocytes can directly mediate killing of leukemia cell lines and chronic lymphocytic leukemia patient neoplastic cells. The present invention shows that human V?1+ NCR+ T cells can be differentiated and expanded from total ?? peripheral blood lymphocytes (PBLs), upon regular in vitro or ex vivo stimulation with ??TCR agonists and ?c-family cytokines. This subset surprisingly expresses NKp30, NKp44 and NKp46, and high levels of Granzyme B that associate with highly enhanced cytotoxicity against lymphoid leukemias.

Abstract: The invention relates to a method for thermoforming synthetic paper, more concretely for thermoforming holding strips consisting of synthetic paper, the strips being used to produce sheet-holding devices of a specific configuration. Said devices can be used in the assembly of sheet holders such as calendars, white sheet dispensers or information cards.

Abstract: An ice buildup inhibitor is disclosed useful for preventing ice damming, in particular in conjunction with the use of a closed gutter. Heat escape through a roof made warm snow pack, causing it to melt and flow down toward the gutter. After moving away from the heated roof, the water may re-freeze and form an ice dam. In the ice buildup inhibitor may be configured to warm in the closed gutter, thereby preventing the formation of an ice dam. They ice buildup inhibitor may be configured to be easily installed onto an existing closed gutter, enabling responsive installation on only those homes experiencing ice damming.

Abstract: The present invention relates to a cell line of lymphocytes comprising ?? T cells, composition and production method thereof, and medical use namely for the use in medicine, namely in cancer immunotherapy. The cell line comprise a sample of human peripheral blood V?1+ ?? T cells expressing functional natural cytotoxicity receptors (NCRs). These V?1+ NCR+ T lymphocytes can directly mediate killing of leukemia cell lines and chronic lymphocytic leukemia patient neoplastic cells. The present invention shows that human V?1+ NCR+ T cells can be differentiated and expanded from total ?? peripheral blood lymphocytes (PBLs), upon regular in vitro or ex vivo stimulation with ??TCR agonists and ?c-family cytokines. This subset surprisingly expresses NKp30, NKp44 and NKp46, and high levels of Granzyme B that associate with highly enhanced cytotoxicity against lymphoid leukemias.

Abstract: A demonstration service receives content from various content providers, and maintains the received content. A retailer can access the demonstration service and select various content to include in demonstration experiences for various groups of demonstration devices in a retailer environment. Demonstration experience descriptions identifying the content that is to be presented by a device as a demonstration experience is obtained by the device from the demonstration service. For content that the device does not have, the device attempts to obtain the content from another device in the same retailer environment. If no other device in the same retailer environment has the content, then the device obtains the content from the demonstration service.

Abstract: A demonstration service receives content from various content providers, and maintains the received content. The content can be provided to the demonstration service at various times, and changed as desired by the content providers. A retailer can access the demonstration service and select various content to include in demonstration experiences for various groups of demonstration devices in a retailer environment. The demonstration experiences can be changed at various times as desired by the retailer. Demonstration experience descriptions and/or changes to demonstration experience descriptions are provided to the demonstration devices, allowing each demonstration device to present a demonstration experience as defined by the retailer.

Abstract: An ice buildup inhibitor is disclosed useful for preventing ice damming, in particular in conjunction with the use of a closed gutter. Heat escape through a roof made warm snow pack, causing it to melt and flow down toward the gutter. After moving away from the heated roof, the water may re-freeze and form an ice dam. In the ice buildup inhibitor may be configured to warm in the closed gutter, thereby preventing the formation of an ice dam. They ice buildup inhibitor may be configured to be easily installed onto an existing closed gutter, enabling responsive installation on only those homes experiencing ice damming.

Abstract: It provides a fastener to hold small cards and paper sheets, includes a base of cardboard, plastic or some other material with condition that provides the desired portability. It also provides a method for inserting paper sheets and cards to the clip.

Abstract: An ice buildup inhibitor is disclosed useful for preventing ice damming, in particular in conjunction with the use of a closed gutter. Heat escape through a roof made warm snow pack, causing it to melt and flow down toward the gutter. After moving away from the heated roof, the water may re-freeze and form an ice dam. In the ice buildup inhibitor may be configured to warm in the closed gutter, thereby preventing the formation of an ice dam. They ice buildup inhibitor may be configured to be easily installed onto an existing closed gutter, enabling responsive installation on only those homes experiencing ice damming.

Abstract: One aspect of the invention provides a method of processing an PPM encoded input signal transmission of data pulses to a data processing apparatus by processing the pulses by lengthening or shortening the pulses to a length within the predetermined acceptance pulse duration range of the data processing apparatus comprising: detecting when the input pulses of the input signal fall below the duration required and lengthening the pulses by a sufficient amount to bring them within the predetermined duration; detecting when the input pulses of the input signal exceed the duration required and reducing the duration of the pulses by a sufficient amount to bring them within the predetermined duration.