Patents by Inventor Daniel Yohannes

Daniel Yohannes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 7-hetero-bicyclo[2.2.1]-heptanes
    Publication number: 20030236405
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: February 27, 2003
    Publication date: December 25, 2003
    Inventors: Daniel Yohannes, Mark W. Bundesmann
  • Heterocyclic compounds as ligands of the GABAA receptor
    Patent number: 6653471
    Abstract: Disclosed are heterocyclic compounds of the formula and the pharmaceutically acceptable salts thereof wherein the variables A, V, Y, J, E, X, T, G, Q, W, Z, b, n and m are defined herein. These compounds are highly selective agonists, antagonists or inverse agonists for GABAA brain receptors or prodrugs of agonists, antagonists or inverse agonists for GABAA brain receptor.
    Type: Grant
    Filed: August 6, 2001
    Date of Patent: November 25, 2003
    Assignee: Neurogen Corporation
    Inventors: Daniel Yohannes, George Maynard, Jun Yuan, Linghong Xie, Kyungae Lee, Manuka Ghosh, George Luke, Xiaojun Liu, Arthur Nagal, Lawrence Vincent, Kevin Currie, Zhe-Quing Wang
  • Novel muscarinic receptor agonists
    Publication number: 20030171349
    Abstract: This invention relates to a novel class of partial or full muscarinic receptor agonists intermediates for their preparation, and pharmaceutical compositions and methods of use for the treatment or prevention of diseases the treatment or prevention of which is mediated by muscarinic receptor agonism.
    Type: Application
    Filed: February 28, 2003
    Publication date: September 11, 2003
    Inventors: Anabella Villalobos, Daniel Yohannes, Jolanta Nowakowski, Dane R. Liston
  • Heterocyclic compounds as ligands of the GABAA receptor
    Publication number: 20030105081
    Abstract: Disclosed are heterocyclic compounds of the formula 1
    Type: Application
    Filed: August 6, 2001
    Publication date: June 5, 2003
    Inventors: Daniel Yohannes, George Maynard, Jun Yuan, Linghong Xie, Kyungae Lee, Manuka Ghosh, George Luke, Xiaojun Liu, Arthur Nagel, Lawrence Vincent, Kevin Currie, Zhe-Quing Wang
  • Cycloalkylpyrrole-3-carboxylic acid derivatives and heterocycloalkylpyrrole-3-carboxylic acid derivatives
    Publication number: 20030069416
    Abstract: This invention relates to cycloalkylpyrrole-3-carboxylic acid derivatives and heterocycloalkylpyrrole-3-carboxylic acid derivatives that bind with high selectively and/or high affinity to the benzodiazepine site of GABAA receptors. This invention also relates to pharmaceutical compositions comprising such compounds and to the use of such compounds in the treatment of central nervous system (CNS) diseases. This invention also relates to the use of these cycloalkylpyrrole-3-carboxylic acid derivatives and heterocycloalkylpyrrole-3-carboxylic acid derivatives in combination with one or more other CNS agents to potentiate the effects of the other CNS agents. Additionally this invention relates to the use such compounds as probes for the detection of GABAA receptors in tissue samples.
    Type: Application
    Filed: April 24, 2002
    Publication date: April 10, 2003
    Applicant: Pfizer Inc.
    Inventors: Daniel Yohannes, George Maynard, Xiaojun Liu
  • Novel muscarinic receptor agonists
    Publication number: 20020103194
    Abstract: This invention relates to a novel class of partial or full muscarinic receptor agonists intermediates for their preparation, and pharmaceutical compositions and methods of use for the treatment or prevention of diseases the treatment or prevention of which is mediated by muscarinic receptor agonism
    Type: Application
    Filed: February 15, 2000
    Publication date: August 1, 2002
    Inventors: Anabella Villalobos, Daniel Yohannes, Jolanta Nowakowski, Dane Liston
  • 7-Hetero-bicyclo[2.2.1]-heptanes
    Publication number: 20020038028
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: November 21, 2001
    Publication date: March 28, 2002
    Inventors: Daniel Yohannes, Mark W. Bundesmann
  • 7-hetero-bicyclo[2.2.1]-heptanes
    Publication number: 20020035262
    Abstract: Compounds of the formula 1
    Type: Application
    Filed: November 21, 2001
    Publication date: March 21, 2002
    Inventors: Daniel Yohannes, Mark W. Bundesmann
  • Muscarinic receptor agonists
    Patent number: 6093733
    Abstract: This invention relates to a novel class of partial or full muscarinic receptor agonists intermediates for their preparation, and pharmaceutical compositions and methods of use for the treatment or prevention of diseases the treatment or prevention of which is mediated by muscarinic receptor agonism.
    Type: Grant
    Filed: April 30, 1997
    Date of Patent: July 25, 2000
    Inventors: Anabella Villalobos, Daniel Yohannes, Jolanta Nowakowski, Dane R. Liston