Abstract: The present disclosure relates to protein molecules that specifically bind to 5T4 and/or 4-1BB. The molecules may have at least one humanized 5T4-binding or 4-1BB-binding domain. Such molecules are useful for the treatment of cancer. The protein molecule binding to 5T4 or 4-1BB may have a second binding domain that binds to another target. The molecules may bind both 5T4-expressing cells and a cell-surface molecule expressed by an effector cell to enhance effector cell activation, proliferation, survival and/or effector-cell mediated cytotoxicity. The disclosure also provides pharmaceutical compositions comprising the 5T4-binding or 4-1BB-binding polypeptide or protein molecules, nucleic acid molecules encoding these polypeptides and methods of making and using these molecules.

Abstract: A single, thick, durable, flexible, transparent plastic sheet, cut to a pre-selected pattern that replaces a vehicle's missing or damaged side or rear glass windows and is for temporary use or pleasure. Also referred to as a plastic window or sheet or a cosmetic window covering, this plastic sheet fits snugly within the seal of the vehicle's door window or rear window frames. Each plastic window sheet may be secured within the window seal/molding using a sturdy, elongated flat rod (also referred to as the “securing device”) made of a hard, thick plastic and may be inserted into a fold located at the top of each plastic sheet (this step is optional). The plastic sheets may be available with UV protection and/or in an assortment of color options, prints, and tints for privacy, style, fun and fashion. This inventive plastic window may also be used on the opposite window of the same vehicle making it reusable, recyclable and eco-friendly product.

Abstract: A hydronic water heating system heats water for various types of heat emitters. A boiler assembly includes a user interface which receives user-defined water temperature set point corresponding to a minimum outdoor temperature, and an integrated controller generates a nonlinear outdoor reset curve between the user-defined set point and a second set point corresponding to maximum outdoor temperature for which heating is required, and regulates the boiler to heat water to a temperature corresponding to a set point along the nonlinear output reset curve and based on a detected outdoor temperature. The nonlinear outdoor reset curve may be generated based on aggregated heat output functions for various types of heat emitters. A linear outdoor reset curve may be generated between a maximum water temperature set point and the user-defined set point, having a slope equal to an instantaneous slope of the nonlinear outdoor reset curve at the user-defined set point.

Abstract: A method comprises displaying a window on a graphical user interface that is presented on a display screen, the window presenting a graphical tool therein; and in response to an input gesture on the graphical user interface, changing the fidelity of the graphical tool presented in the window.

Abstract: Introducing a solar energy based technology that introduces mobile and electronic devices to energy and power by way solar integration. Solar panels will be positioned on the backside of the device's outer shell where it will also be embedded within the outer casing. The solar energy to the mobile terminal's power management system will function in one or more of the following modes: 1) allow usage of mobile devices (also known as “cellular” devices) with battery as a back-up energy source; 2) provide the ability to recharge a low or dead battery by way of the trickle charge effect when device is not in use; and/or 3) the use of a switch-mode-power-supply (SMPS) which will allow mobile device to be manually switched between energy usage using either solar/light power or a battery.

Abstract: A multi-monitor computer system includes a plurality of display devices communicating with at least one computing device executing an application management procedure. The application management procedure enables an application window available on one display device to be moved entirely to another display device by selecting the other display device from a dialog box displayed in response to a pointer-dragging input gesture on the application window.

Abstract: In a distributed computer network where displayed information is shared between at least two computers, a method of enabling remote control of a host computer having a display region that is to be shared with at least one client computer. The method includes tracking time lapsed since a local user input event has occurred while the host computer is under local control and in the event that the time lapsed exceeds a threshold, enabling remote control of the host computer by a client computer.

Abstract: A latch mechanism is provided for securing a storage compartment door within a vehicle. The latch mechanism includes a mounting bracket, a handle, and an undivided, one piece latching member. The latching member includes a main body portion, a first pliable leg portion, a second pliable leg portion, a first post portion, and a second post portion. The latching member is in a relaxed position when the handle is in the latched position and a flexed position when the handle is in the unlatched position. The handle includes at least one abutment member for displacing the main body portion of the latching member as the handle is pivoted from the latched position to the unlatched position. Displacement of the main body portion causes the first and second pliable leg portions to resiliently retract which retracts the first post member and the second post member from extended post positions to retracted post positions.

Abstract: A multi-monitor computer system includes a plurality of display devices communicating with at least one computing device executing an application management procedure. The application management procedure enables an application window available on one display device to be moved entirely to another display device by selecting the other display device from a dialog box displayed in response to a pointer-dragging input gesture on the application window.

Abstract: A latch mechanism is provided for securing a storage compartment door within a vehicle. The latch mechanism includes a mounting bracket, a handle, and an undivided, one piece latching member. The latching member includes a main body portion, a first pliable leg portion, a second pliable leg portion, a first post portion, and a second post portion. The latching member is in a relaxed position when the handle is in the latched position and a flexed position when the handle is in the unlatched position. The handle includes at least one abutment member for displacing the main body portion of the latching member as the handle is pivoted from the latched position to the unlatched position. Displacement of the main body portion causes the first and second pliable leg portions to resiliently retract which retracts the first post member and the second post member from extended post positions to retracted post positions.

Abstract: The disclosure is directed to a test media reader module including a housing, a membrane, and an optical imager. The housing is configured to receive a test media adapter and has a barrier wall configured to separate the test media adapter from an interior of the housing. The barrier wall includes a window having an interior side and an exterior side. The membrane is transparent to a wavelength useful for imaging test media in the test media adapter. The membrane has a reactive region and overlies at least a portion of the exterior side of the window. The optical imager is located interior to the housing and is configured to image the test media located on the exterior side of the window along an optical path extending through the window and the membrane.

Abstract: A light source includes a first set of first beam sources having parallel output beams lying in a first-beam-source plane and a second set of second beam sources having parallel output beams lying in a second-beam-source plane. The first-beam-source output beams are parallel to the second-beam-source output beams, but are spatially offset in a direction perpendicular to the first-beam-source output beams. A spatial optical interleaver disposed receives the first-beam-source output beams and the second-beam-source output beams. The first-beam-source output beams pass unimpeded through a set of first-beam openings in the spatial optical interleaver, and the second-beam-source output beams are reflected parallel to the first-beam-source output beams and in the first-beam-source plane.

Abstract: In a distributed computer network where displayed information is shared between at least two computers, a method of enabling remote control of a host computer having a display region that is to be shared with at least one client computer. The method includes tracking time lapsed since a local user input event has occurred while the host computer is under local control and in the event that the time lapsed exceeds a threshold, enabling remote control of the host computer by a client computer.

Abstract: A desktop sharing system and method are provided. A desktop sharing application permits a selected display region on a first computer's desktop to be shared with other computers. The desktop sharing application permits another computer to assume control and share a selected display region of the other computer's desktop during a conference.

Abstract: A desktop sharing system and method are provided. A desktop sharing application permits a selected display region on a first computer's desktop to be shared with other computers. The desktop sharing application permits another computer to assume control and share a selected display region of the other computer's desktop during a conference.

Abstract: The disclosure is directed to a test media reader module including a housing, a membrane, and an optical imager. The housing is configured to receive a test media adapter and has a barrier wall configured to separate the test media adapter from an interior of the housing. The barrier wall includes a window having an interior side and an exterior side. The membrane is transparent to a wavelength useful for imaging test media in the test media adapter. The membrane has a reactive region and overlies at least a portion of the exterior side of the window. The optical imager is located interior to the housing and is configured to image the test media located on the exterior side of the window along an optical path extending through the window and the membrane.