Patents by Inventor Danxi Li

Danxi Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES THAT BIND IL-4 AND/OR IL-13 AND THEIR USES
    Publication number: 20230235088
    Abstract: The present invention relates to novel humanized anti-IL-4 and IL-13 antibodies and fragments thereof and novel bispecific antibodies and fragments thereof that specifically bind to IL-4 and IL-13. The invention also includes uses of the antibodies to treat or prevent IL-4 and/or IL-13 mediated diseases or disorders, including allergic asthma and dermatitis.
    Type: Application
    Filed: August 10, 2022
    Publication date: July 27, 2023
    Inventors: Ercole RAO, Vincent Mikol, Danxi Li, Jochen Kruip, Matthew Davison
  • Antibodies that bind IL-4 and/or IL-13 and their uses
    Patent number: 11453727
    Abstract: The present invention relates to novel humanized anti-IL-4 and IL-13 antibodies and fragments thereof and novel bispecific antibodies and fragments thereof that specifically bind to IL-4 and IL-13. The invention also includes uses of the antibodies to treat or prevent IL-4 and/or IL-13 mediated diseases or disorders, including allergic asthma and dermatitis.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: September 27, 2022
    Assignee: SANOFI
    Inventors: Ercole Rao, Vincent Mikol, Danxi Li, Jochen Kruip, Matthew Davison
  • USES OF A DUAL V REGION ANTIBODY-LIKE PROTEIN
    Publication number: 20210221882
    Abstract: Uses of a dual V region antibody-like protein or a fragment of a dual V region antibody-like region.
    Type: Application
    Filed: April 7, 2021
    Publication date: July 22, 2021
    Inventors: Florent C. BENDER, Danxi LI, Anne MINNICH, Amirtha NAADIMUTHU, Ercole RAO, Brian N. SWANSON, Lei TANG, Haixin YU, Otmane BOUSSIF, Sophie CARAYON
  • Dual Variable Region Antibody-Like Binding Proteins Having Cross-Over Binding Region Orientation
    Publication number: 20210189011
    Abstract: The invention provides antibody-like binding proteins comprising four polypeptide chains that form four antigen binding sites, wherein each pair of polypeptides forming an antibody-like binding protein possesses dual variable domains having a cross-over orientation. The invention also provides methods for making such antigen-like binding proteins.
    Type: Application
    Filed: December 28, 2020
    Publication date: June 24, 2021
    Inventors: Nicolas Baurin, Christian Beil, Carsten Corvey, Christian Lange, Danxi Li, Vincent Mikol, Anke Steinmetz, Ercole Rao
  • Uses of a dual V region antibody-like protein
    Patent number: 11008389
    Abstract: Uses of a dual V region antibody-like protein or a fragment of a dual V region antibody-like region.
    Type: Grant
    Filed: July 8, 2016
    Date of Patent: May 18, 2021
    Assignee: SANOFI
    Inventors: Florent C. Bender, Danxi Li, Anne Minnich, Amirtha Naadimuthu, Ercole Rao, Brian N. Swanson, Lei Tang, Haixin Yu, Otmane Boussif, Sophie Carayon
  • ANTIBODIES THAT BIND IL-4 AND/OR IL-13 AND THEIR USES
    Publication number: 20210047437
    Abstract: The present invention relates to novel humanized anti-IL-4 and IL-13 antibodies and fragments thereof and novel bispecific antibodies and fragments thereof that specifically bind to IL-4 and IL-13. The invention also includes uses of the antibodies to treat or prevent IL-4 and/or IL-13 mediated diseases or disorders, including allergic asthma and dermatitis.
    Type: Application
    Filed: July 28, 2020
    Publication date: February 18, 2021
    Inventors: Ercole RAO, Vincent MIKOL, Danxi LI, Jochen KRUIP, Matthew DAVISON
  • Antibodies that bind IL-4 and/or IL-13 and their uses
    Patent number: 10759871
    Abstract: The present invention relates to novel humanized anti-IL-4 and IL-13 antibodies and fragments thereof and novel bispecific antibodies and fragments thereof that specifically bind to IL-4 and IL-13. The invention also includes uses of the antibodies to treat or prevent IL-4 and/or IL-13 mediated diseases or disorders, including allergic asthma and dermatitis.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: September 1, 2020
    Assignee: SANOFI
    Inventors: Ercole Rao, Vincent Mikol, Danxi Li, Jochen Kruip, Matthew Davison
  • Dual Variable Region Antibody-Like Binding Proteins Having Cross-Over Binding Region Orientation
    Publication number: 20180155450
    Abstract: The invention provides antibody-like binding proteins comprising four polypeptide chains that form four antigen binding sites, wherein each pair of polypeptides forming an antibody-like binding protein possesses dual variable domains having a cross-over orientation. The invention also provides methods for making such antigen-like binding proteins.
    Type: Application
    Filed: December 8, 2017
    Publication date: June 7, 2018
    Inventors: Nicolas Baurin, Christian Beil, Carsten Corvey, Christian Lange, Danxi Li, Vincent Mikol, Anke Steinmetz, Ercole Rao
  • ANTIBODIES THAT BIND IL-4 AND/OR IL-13 AND THEIR USES
    Publication number: 20180030156
    Abstract: The present invention relates to novel humanized anti-IL-4 and IL-13 antibodies and fragments thereof and novel bispecific antibodies and fragments thereof that specifically bind to IL-4 and IL-13. The invention also includes uses of the antibodies to treat or prevent IL-4 and/or IL-13 mediated diseases or disorders, including allergic asthma and dermatitis.
    Type: Application
    Filed: July 10, 2017
    Publication date: February 1, 2018
    Inventors: Ercole RAO, Vincent MIKOL, Danxi LI, Jochen KRUIP, Matthew DAVISON
  • Antibodies that bind IL-4 and/or IL-13 and their uses
    Patent number: 9738728
    Abstract: The present invention relates to novel humanized anti-IL-4 and IL-13 antibodies and fragments thereof and novel bispecific antibodies and fragments thereof that specifically bind to IL-4 and IL-13. The invention also includes uses of the antibodies to treat or prevent IL-4 and/or IL-13 mediated diseases or disorders, including allergic asthma and dermatitis.
    Type: Grant
    Filed: March 11, 2013
    Date of Patent: August 22, 2017
    Assignee: Sanofi
    Inventors: Ercole Rao, Vincent Mikol, Danxi Li, Jochen Kruip, Matthew Davison
  • Antibodies that bind IL-4 and/or IL-13 and their uses
    Patent number: 9732162
    Abstract: The present invention relates to novel humanized anti-IL-4 and IL-13 antibodies and fragments thereof and novel bispecific antibodies and fragments thereof that specifically bind to IL-4 and IL-13. The invention also includes uses of the antibodies to treat or prevent IL-4 and/or IL-13 mediated diseases or disorders, including allergic asthma and dermatitis.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: August 15, 2017
    Assignee: Sanofi
    Inventors: Ercole Rao, Vincent Mikol, Danxi Li, Jochen Kruip, Matthew Davison
  • USES OF A DUAL V REGION ANTIBODY-LIKE PROTEIN
    Publication number: 20170029498
    Abstract: Uses of a dual V region antibody-like protein or a fragment of a dual V region antibody-like region.
    Type: Application
    Filed: July 8, 2016
    Publication date: February 2, 2017
    Inventors: Florent BENDER, Danxi LI, Anne MINNICH, Amirtha NAADIMUTHU, Ercole RAO, Brian N. SWANSON, Lei TANG, Haixin YU
  • Dual Variable Region Antibody-Like Binding Proteins Having Cross-Over Binding Region Orientation
    Publication number: 20160200811
    Abstract: The invention provides antibody-like binding proteins comprising four polypeptide chains that form four antigen binding sites, wherein each pair of polypeptides forming an antibody-like binding protein possesses dual variable domains having a cross-over orientation. The invention also provides methods for making such antigen-like binding proteins.
    Type: Application
    Filed: November 20, 2015
    Publication date: July 14, 2016
    Inventors: Nicolas Baurin, Christian Beil, Carsten Corvey, Christian Lange, Danxi Li, Vincent Mikol, Anke Steinmetz, Ercole Rao
  • Dual variable region antibody-like binding proteins having cross-over binding region orientation
    Patent number: 9221917
    Abstract: The invention provides antibody-like binding proteins comprising four polypeptide chains that form four antigen binding sites, wherein each pair of polypeptides forming an antibody-like binding protein possesses dual variable domains having a cross-over orientation. The invention also provides methods for making such antigen-like binding proteins.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 29, 2015
    Assignee: SANOFI
    Inventors: Nicolas Baurin, Chirstian Biel, Carsten Corvey, Christian Lange, Danxi Li, Vincent Mikol, Anke Steinmetz, Ercole Rao
  • Dual variable region antibody-like binding proteins having cross-over binding region orientation
    Patent number: 9181349
    Abstract: The invention provides antibody-like binding proteins comprising four polypeptide chains that form four antigen binding sites, wherein each pair of polypeptides forming an antibody-like binding protein possesses dual variable domains having a cross-over orientation. The invention also provides methods for making such antigen-like binding proteins.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: November 10, 2015
    Assignee: SANOFI
    Inventors: Nicolas Baurin, Chirstian Biel, Carsten Corvey, Christian Lange, Danxi Li, Vincent Mikol, Anke Steinmetz, Ercole Rao
  • Dual Variable Region Antibody-Like Binding Proteins Having Cross-Over Binding Region Orientation
    Publication number: 20140056895
    Abstract: The invention provides antibody-like binding proteins comprising four polypeptide chains that form four antigen binding sites, wherein each pair of polypeptides forming an antibody-like binding protein possesses dual variable domains having a cross-over orientation. The invention also provides methods for making such antigen-like binding proteins.
    Type: Application
    Filed: March 14, 2013
    Publication date: February 27, 2014
    Applicant: SANOFI
    Inventors: Nicolas Baurin, Chirstian Biel, Carsten Corvey, Christian Lange, Danxi Li, Vincent Mikol, Anke Steinmetz, Ercole Rao
  • ANTIBODIES THAT BIND IL-4 AND/OR IL-13 AND THEIR USES
    Publication number: 20140023649
    Abstract: The present invention relates to novel humanized anti-IL-4 and IL-13 antibodies and fragments thereof and novel bispecific antibodies and fragments thereof that specifically bind to IL-4 and IL-13. The invention also includes uses of the antibodies to treat or prevent IL-4 and/or IL-13 mediated diseases or disorders, including allergic asthma and dermatitis.
    Type: Application
    Filed: March 15, 2013
    Publication date: January 23, 2014
    Applicant: SANOFI
    Inventors: Ercole RAO, Vincent MIKOL, Danxi LI, Jochen KRUIP, Matthew DAVISON
  • Dual Variable Region Antibody-Like Binding Proteins Having Cross-Over Binding Region Orientation
    Publication number: 20140011238
    Abstract: The invention provides antibody-like binding proteins comprising four polypeptide chains that form four antigen binding sites, wherein each pair of polypeptides forming an antibody-like binding protein possesses dual variable domains having a cross-over orientation. The invention also provides methods for making such antigen-like binding proteins.
    Type: Application
    Filed: March 14, 2013
    Publication date: January 9, 2014
    Applicant: SANOFI
    Inventors: Nicolas Baurin, Chirstian Biel, Carsten Corvey, Christian Lange, Danxi Li, Vincent Mikol, Anke Steinmetz, Ercole Rao
  • USES OF A DUAL V REGION ANTIBODY-LIKE PROTEIN
    Publication number: 20130344074
    Abstract: Uses of a dual V region antibody-like protein or a fragment of a dual V region antibody-like region.
    Type: Application
    Filed: March 15, 2012
    Publication date: December 26, 2013
    Applicant: SANOFI
    Inventors: Florent Bender, Danxi Li, Anne Minnich, Amirtha Naadimuthu, Ercole Rao, Brian N. Swanson, Lei Tang, Haixin Yu
  • Dual Variable Region Antibody-Like Binding Proteins Having Cross-Over Binding Region Orientation
    Publication number: 20130345404
    Abstract: The invention provides antibody-like binding proteins comprising four polypeptide chains that form four antigen binding sites, wherein each pair of polypeptides forming an antibody-like binding protein possesses dual variable domains having a cross-over orientation. The invention also provides methods for making such antigen-like binding proteins.
    Type: Application
    Filed: March 14, 2013
    Publication date: December 26, 2013
    Applicant: SANOFI
    Inventors: Nicolas Baurin, Chirstian Biel, Carsten Corvey, Christian Lange, Danxi Li, Vincent Mikol, Anke Steinmetz, Ercole Rao