Patents by Inventor Danxi Li

Danxi Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RRP sequences and knockout mice and uses thereof
    Publication number: 20030165497
    Abstract: RRP genes are identified as modulators of the p53 or p21 pathway, and thus are therapeutic targets for disorders associated with defective p53 or p21 function. Methods for identifying modulators of p53 or p21, comprising screening for agents that modulate the activity of RRP are provided. Modulating agents identified using the methods of the invention can be used to specifically inhibit growth of tumor cells that overexpress an RRP protein. mRRP1 knockout mice are also provided.
    Type: Application
    Filed: January 23, 2002
    Publication date: September 4, 2003
    Inventors: Mario N. Lioubin, Lori Friedman, Marcia Belvin, Jeffrey S. Larson, Changyou Chen, Stephanie A. Robertson, Wen Shi, Jocelyn Chan, Danxi Li, Helen Francis-Lang, Gregory D. Plowman, Roel P. Funke, Michael Schoor, Branko Zevnik, Gunther Kauselmann, Hartmut Tintrup
  • LRRCAPs as modifiers of the p53 pathway and methods of use
    Publication number: 20030138431
    Abstract: Human LRRCAPS genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of LRRCAPS are provided.
    Type: Application
    Filed: October 21, 2002
    Publication date: July 24, 2003
    Inventors: Marcia Belvin, Lothar Schleithoff, Gregory D. Plowman, Roel P. Funke, Mario N. Lioubin, Danxi Li, Helen Francis-Lang
  • IGs as modifiers of the p53 pathway and methods of use
    Publication number: 20030087266
    Abstract: Human IG genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of IG are provided.
    Type: Application
    Filed: June 3, 2002
    Publication date: May 8, 2003
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke, Mario N. Lioubin
  • CADs as modifiers of the p53 pathway and methods of use
    Publication number: 20030036076
    Abstract: Human CAD genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of CAD are provided.
    Type: Application
    Filed: June 3, 2002
    Publication date: February 20, 2003
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke
  • P5CRs as modifiers of the p53 pathway and methods of use
    Publication number: 20030036078
    Abstract: Human P5CR genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of P5CR are provided.
    Type: Application
    Filed: June 3, 2002
    Publication date: February 20, 2003
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke, Stefan Engst
  • HPRP4s as modifiers of the p53 pathway and methods of use
    Publication number: 20030027230
    Abstract: Human hPRP4 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of hPRP4 are provided.
    Type: Application
    Filed: August 2, 2002
    Publication date: February 6, 2003
    Inventors: Lori Friedman, Gregory D. Plowman, Tak Hung, Helen Francis-Lang, Danxi Li, Roel P. Funke, Michael Costa
  • SLC7s as modifiers of the p53 pathway and methods of use
    Publication number: 20030027188
    Abstract: Human SLC7 genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of SLC7 are provided.
    Type: Application
    Filed: June 5, 2002
    Publication date: February 6, 2003
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke
  • ADSLs as modifiers of the p53 pathway and methods of use
    Publication number: 20030022209
    Abstract: Human ADSL genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of ADSL are provided.
    Type: Application
    Filed: June 3, 2002
    Publication date: January 30, 2003
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke, Stefan Engst
  • HADHs as modifiers of the p21 pathway and methods of use
    Publication number: 20030022222
    Abstract: Human HADH genes are identified as modulators of the p21 pathway, and thus are therapeutic targets for disorders associated with defective p21 function. Methods for identifying modulators of p21, comprising screening for agents that modulate the activity of HADH are provided.
    Type: Application
    Filed: July 10, 2002
    Publication date: January 30, 2003
    Inventors: Lori Friedman, Gregory D. Plowman, Roel P. Funke, Marcia Belvin, Danxi Li, Stephanie A. Robertson
  • PRMTs as modifiers of the p53 pathway and methods of use
    Publication number: 20030017489
    Abstract: Human PRMT genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of PRMT are provided.
    Type: Application
    Filed: June 5, 2002
    Publication date: January 23, 2003
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke
  • HS2STs as modifiers of the p53 pathway and methods of use
    Publication number: 20030013144
    Abstract: Human HS2ST genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of HS2ST are provided.
    Type: Application
    Filed: June 3, 2002
    Publication date: January 16, 2003
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke
  • PIBs as modifiers of the p53 pathway and methods of use
    Publication number: 20020192695
    Abstract: Human PIB genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of PIB are provided.
    Type: Application
    Filed: June 3, 2002
    Publication date: December 19, 2002
    Inventors: Lori Friedman, Gregory D. Plowman, Marcia Belvin, Helen Francis-Lang, Danxi Li, Roel P. Funke
  • Human RRP sequences and methods of use
    Publication number: 20020022029
    Abstract: Rhomboid Related Proteins (RRPs), involved in the EGFR signaling pathway, are provided. Transgenic, nonhuman mammals containing a transgene encoding an RRP polypeptide or a gene effecting the expression of an RRP polypeptide, along with methods of modulating the interaction of RRP proteins with their pathway members, and methods of screening for agents that modulate the interaction of an RRP polypeptide with an RRP binding target, such as RRP-specific antibodies and small molecules identified in high throughput screens, are also provided.
    Type: Application
    Filed: July 18, 2001
    Publication date: February 21, 2002
    Inventors: Mario N. Lioubin, Lori Friedman, Marcia Belvin, Jeffery S. Larson, Changyou Chen, Stephanie A. Roberston, Wen Shi, Jocelyn Chan, Danxi Li