Patents by Inventor Datong Tang

Datong Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VIRAL INHIBITORS, THE SYNTHESIS THEROF, AND INTERMEDIATES THERETO
    Publication number: 20260108495
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir.
    Type: Application
    Filed: November 21, 2025
    Publication date: April 23, 2026
    Inventors: Jeffrey Scott DEPUE, Suresh Kumar TIPPARAJU, Helge Alfred REISCH, Datong TANG, Kishore RAMACHANDRAN
  • VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20260097018
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir.
    Type: Application
    Filed: November 21, 2025
    Publication date: April 9, 2026
    Inventors: Jeffrey Scott DEPUE, Suresh Kumar TIPPARAJU, Helge Alfred REISCH, Datong TANG, Kishore RAMACHANDRAN
  • VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20260076946
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir.
    Type: Application
    Filed: November 21, 2025
    Publication date: March 19, 2026
    Inventors: Jeffrey Scott DEPUE, Suresh Kumar TIPPARAJU, Helge Alfred REISCH, Datong TANG, Kishore RAMACHANDRAN
  • VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20260076945
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir.
    Type: Application
    Filed: November 21, 2025
    Publication date: March 19, 2026
    Inventors: Jeffrey Scott DEPUE, Suresh Kumar TIPPARAJU, Helge Alfred REISCH, Datong TANG, Kishore RAMACHANDRAN
  • Viral inhibitors, the synthesis thereof, and intermediates thereto
    Patent number: 12527771
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir. Maribavir is a benzimidazole riboside and is useful as an antiviral.
    Type: Grant
    Filed: July 7, 2025
    Date of Patent: January 20, 2026
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Jeffrey Scott Depue, Suresh Kumar Tipparaju, Helge Alfred Reisch, Datong Tang, Kishore Ramachandran
  • VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20250332146
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir.
    Type: Application
    Filed: July 7, 2025
    Publication date: October 30, 2025
    Inventors: Jeffrey Scott DEPUE, Suresh Kumar TIPPARAJU, Helge Alfred REISCH, Datong TANG, Kishore RAMACHANDRAN
  • Viral inhibitors, the synthesis thereof, and intermediates thereto
    Patent number: 12377078
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir. Maribavir (((2S,3S,4R,5S)-2-(5,6-dichloro-2-(isopropylamino)-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol) is a benzimidazole riboside and is an orally available antiviral medication against cytomegalovirus (CMV).
    Type: Grant
    Filed: July 18, 2024
    Date of Patent: August 5, 2025
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Jeffrey Scott Depue, Suresh Kumar Tipparaju, Helge Alfred Reisch, Datong Tang, Kishore Ramachandran
  • Viral inhibitors, the synthesis thereof, and intermediates thereto
    Patent number: 12295941
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir. Maribavir (((2S,3S,4R,5S)-2-(5,6-dichloro-2-(isopropylamino)-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol) is a benzimidazole riboside and is an orally available antiviral medication against cytomegalovirus (CMV).
    Type: Grant
    Filed: July 18, 2024
    Date of Patent: May 13, 2025
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Jeffrey Scott Depue, Suresh Kumar Tipparaju, Helge Alfred Reisch, Datong Tang, Kishore Ramachandran
  • Viral inhibitors, the synthesis thereof, and intermediates thereto
    Patent number: 12295940
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir. Maribavir (((2S,3S,4R,5S)-2-(5,6-dichloro-2-(isopropylamino)-1H-benzo[d]imidazol-1-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol) is a benzimidazole riboside and is an orally available antiviral medication against cytomegalovirus (CMV).
    Type: Grant
    Filed: July 18, 2024
    Date of Patent: May 13, 2025
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Jeffrey Scott Depue, Suresh Kumar Tipparaju, Helge Alfred Reisch, Datong Tang, Kishore Ramachandran
  • VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20240366647
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir.
    Type: Application
    Filed: July 18, 2024
    Publication date: November 7, 2024
    Inventors: Jeffrey Scott DEPUE, Suresh Kumar TIPPARAJU, Helge Alfred REISCH, Datong TANG, Kishore RAMACHANDRAN
  • VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20240366645
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir.
    Type: Application
    Filed: July 18, 2024
    Publication date: November 7, 2024
    Inventors: Jeffrey Scott DEPUE, Suresh Kumar TIPPARAJU, Helge Alfred REISCH, Datong TANG, Kishore RAMACHANDRAN
  • VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20240366646
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir.
    Type: Application
    Filed: July 18, 2024
    Publication date: November 7, 2024
    Inventors: Jeffrey Scott DEPUE, Suresh Kumar TIPPARAJU, Helge Alfred REISCH, Datong TANG, Kishore RAMACHANDRAN
  • VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20240277748
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir.
    Type: Application
    Filed: October 11, 2023
    Publication date: August 22, 2024
    Inventors: Jeffrey Scott DePue, Suresh Kumar Tipparaju, Helge Alfred Reisch, Datong Tang, Kishore Ramachandran
  • VIRAL INHIBITORS, THE SYNTHESIS THEREOF, AND INTERMEDIATES THERETO
    Publication number: 20240189286
    Abstract: The present disclosure discloses compositions comprising maribavir, methods of providing the same, and compositions providing intermediates useful in providing maribavir.
    Type: Application
    Filed: December 29, 2023
    Publication date: June 13, 2024
    Inventors: Jeffrey Scott DePue, Suresh Kumar Tipparaju, Helge Alfred Reisch, Datong Tang, Kishore Ramachandran
  • Processes for the preparation of 2-fluoro 6-11 bicyclic erythromycin derivatives
    Patent number: 9242974
    Abstract: The present invention relates to processes and intermediates for the preparation of 2-fluoro 6-11 bicyclic erythromycin derivatives.
    Type: Grant
    Filed: September 6, 2013
    Date of Patent: January 26, 2016
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Guoyou Xu, Datong Tang, In Jong Kim, Ly Tam Phan, Yat Sun Or, Zhe Wang
  • Quinoxalinyl derivatives
    Patent number: 8962551
    Abstract: The present invention relates to compounds of Formula I or II, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising a compound of the present invention.
    Type: Grant
    Filed: December 3, 2008
    Date of Patent: February 24, 2015
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Deqiang Niu, Dong Liu, Joel D. Moore, Guoyou Xu, Ying Sun, Yonghua Gai, Datong Tang, Yat Sun Or, Zhe Wang
  • Processes for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives
    Patent number: 8927739
    Abstract: The present invention relates generally to an improved process for the preparation of 5-azaspiro[2.4]heptane-6-carboxylic acid and its derivatives which are useful intermediates in the synthesis of biologically active molecules, especially in the synthesis of hepatits C virus NS5A inhibitors.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: January 6, 2015
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Yao-Ling Qiu, Xiaowen Peng, In Jong Kim, Hui Cao, Datong Tang, Yat Sun Or, Guoqiang Wang, Guoyou Xu
  • Processes for the preparation of novel benzimidazole derivatives
    Patent number: 8921573
    Abstract: The present invention relates to processes and intermediates for the preparation of novel benzimidazole derivatives, especially in the synthesis of hepatitis C virus NS5A inhibitors.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: December 30, 2014
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Datong Tang, Guoyou Xu, Xiaowen Peng, Lu Ying, Ce Wang, Hui Cao, Jiang Long, In Jong Kim, Guoqiang Wang, Yao-Ling Qiu, Yat Sun Or
  • PROCESSES FOR THE PREPARATION OF NOVEL BENZIMIDAZOLE DERIVATIVES
    Publication number: 20140316143
    Abstract: The present invention relates to processes and intermediates for the preparation of novel benzimidazole derivatives, especially in the synthesis of hepatitis C virus NS5A inhibitors.
    Type: Application
    Filed: April 16, 2014
    Publication date: October 23, 2014
    Applicant: ENANTA PHARMACEUTICALS, INC.
    Inventors: Datong Tang, Guoyou Xu, Xiaowen Peng, Lu Ying, Ce Wang, Hui Cao, Jiang Long, In Jong Kim, Guoqiang Wang, Yao-Ling Qiu, Yat Sun Or
  • Quinoxalinyl macrocyclic hepatitis C virus serine protease inhibitors
    Patent number: 8809264
    Abstract: The present invention relates to compounds, including compounds of Formula I, or a pharmaceutically acceptable salt, ester, or prodrug, thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Grant
    Filed: June 26, 2007
    Date of Patent: August 19, 2014
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Deqiang Niu, Dong Liu, Joel D. Moore, Guoyou Xu, Ying Sun, Yonghua Gai, Datong Tang, Yat Sun Or, Zhe Wang