Abstract: Disclosed are methods, systems, devices, apparatus, media, design structures, and other implementations, including a method that includes receiving, at a local device from a remote device, query data representative of a question relating to source content of a source document of a repository of a plurality of source documents, with the source content being associated with transformed content accessible from the local device. The method further includes generating, in response to determination, at the local device, of a match between the query data and at least one portion of the transformed content, output data comprising one or more of a pointer to access, in the source document accessible from the remote device, at least one portion of the source document corresponding to the at least one portion of the transformed content, or a copy of the at least one portion of the source document.

Abstract: Embodiments are described for a stabilization system configured, in some embodiments, for stabilizing image capture from an aerial vehicle (e.g., a UAV). According to some embodiments, the stabilization systems employs both active and passive stabilization means. A passive stabilization assembly includes a counter-balanced suspension system that includes an elongated arm that extends into and is coupled to the body of a vehicle. The counter-balanced suspension system passively stabilizes a mounted device such as an image capture device to counter motion of the UAV while in use. In some embodiment the counter-balanced suspension system passively stabilizes a mounted image capture assembly that includes active stabilization means (e.g., a motorized gimbal and/or electronic image stabilization). In some embodiments, the active and passive stabilization means operate together to effectively stabilize a mounted image capture device to counter a wide range of motion characteristics.

Abstract: Disclosed adjustable retaining arm systems can include a multi-segmented, articulable arm that holds one or more interchangeable tools and can be made relaxed to set a desired position and made rigid to fix the desired position by adjusting tension in a cable running through the arm. The arm can quickly attach and detach from a support structure. The support structure include a cable tensioning system, sensors, control system, power system, etc. A user input device, such as a foot pedal or button on the arm, can be used by a surgeon to change the arm between relaxed and rigid states. The arm and attachable tools can be detachable, disposable and/or sterilizable, while other system components can remain mounted in a fixed location as the arm is removed and replaced. The arm can hold multiple tools in any desired orientation around subject work location.

Abstract: A drone and method for responding to a high-threat target. The drone may be used to strike a firearm or weapon in the possession of a high-threat target or the drone may comprise one or more firearm malfunction devices attached to the drone, wherein the drone deploys the device to disable or prevent the high-threat target from accessing the firearm or weapon and/or distract a high-threat target.

Abstract: Concepts presented herein relate to an interface module that can be electrically coupled to an electrical stimulation generator, a radio frequency generator and an instrument. A selection module is coupled to the interface module and operates in a first mode to deliver electrical stimulation signals from the electrical stimulation generator to the instrument and in a second mode to deliver radio frequency signals from the radio frequency generator to the instrument.

Abstract: The present disclosure relates to a composition that includes a first copolymer having a first repeat unit and a second repeat unit as defined by Structure (I) where is a covalent bond, U1 is a molar fraction of the first repeat unit, (1?U1) is a molar fraction of the second repeat unit, 0?n?20, 0?m?20, 0<U1?1.0, R is a linking group covalently linking the first copolymer to a second copolymer by the covalent bond, and R includes carbon, hydrogen, and sulfur.

Abstract: The invention provides siRNA compositions for inhibiting gene expression in targeted cells. A multi-targeting siR-NA-aptamer platform is provided that is efficiently delivered and is processed by cellular RNAi machinery to produce one, two or more siRNAs. Methods of using the multi-targeting siRNA-aptamer for selectively targeting cancer cells to downregulate the expression of multiple genes are also provided.

Abstract: The invention provides siRNA compositions for inhibiting gene expression in targeted cells.

Abstract: Method of processing a polycrystalline diamond element may include laser ablating at least a portion of a polycrystalline diamond element to form a laser-shaped surface and exposing at least a portion of the laser-shaped surface to a leaching solution to define a leached polycrystalline diamond volume and an unleached polycrystalline diamond volume.

Abstract: Functionality is disclosed herein for using an interactive content service to provide content. A user may interact with the interactive content service to access interactive content, such as interactive fiction, interactive text adventure games, and other interactive content. A user may also use the interactive content to receive auditory output from applications configured to provide text-based content. The interactive content service maintains state information that identifies the current state of the interactive content. For example, before starting a particular interactive adventure game, the state identifies a beginning location within the interactive content. As the user interacts with the game, the interactive content service updates the state of the user within the game.

Abstract: An oven comprising a multi-door operating apparatus is provided. In one example, the multi-door operating apparatus comprises a first panel comprising a first plurality of grooves that traverse a first inside surface of the first panel and a second panel comprising a second plurality of grooves that traverse a second inside surface of the second panel, wherein first inside surface faces the second inside surface, and wherein the first plurality of grooves and the second plurality of grooves extend in a first direction and then turn to extend in a second direction. The multi-door operating apparatus further comprises two or more oven doors configured to move in the first direction and turn to the second direction via projections that extend from the respective oven doors into the first plurality of groves and the second plurality of grooves.

Abstract: The present disclosure relates to a method of displaying two sets of characters, the method being implemented by a computing device, said method comprising: receiving, by the computing device, a first set of characters; receiving, by the computing device, a second set of characters; modifying, by the computing device, an appearance of one or more of the second set of characters to receive, without overlap, one or more of the first set of characters; and displaying, on a device screen, the one or more of the first set of characters and the modified second set of characters, wherein the one or more of the first set of characters are embedded in the modified second set of characters.

Abstract: The present disclosure relates, in general, to improved processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)-benzamide, particularly large-scale processes for manufacturing 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide and intermediates used in such processes.

Abstract: Disclosed are compositions comprising: a trans-splicing nucleic acid comprising (a) one or more replacement domains that encode a therapeutic sequence operably linked to; (b) one or more intronic domains that promote RNA splicing of the replacement domain comprising a trans-splicing enhancer sequence; and (c) one or more antisense domains that promote binding to a target RNA molecule, wherein an RNA trans-splicing reaction promotes highly efficient insertion of the replacement domain into a target RNA. Methods of making and methods of using compositions of the disclosure are also provided, including but not limited to compositions of the disclosure that may be used in the treatment of a disease or disorder in a patient or subject. Example disease or disorders of the disclosure include genetic and epigenetic diseases or disorders.

Abstract: Methods and systems for controlling an electric motor using a motor controller including a processor are provided. The method includes transmitting, by the processor, a no-spin signal commanding the electric motor not to spin, receiving temperature information associated with a temperature of the electric motor, comparing the temperature information to a predetermined threshold temperature to determine whether the temperature is at a sufficient level to prevent icing, and adjusting current applied to the electric motor when the temperature measurement is below the predetermined threshold.

Abstract: Electrochemical CO2 reduction is a promising technology to capture and convert CO2 to valuable chemicals. Disclosed herein is the effect of anolyte on the effective morphology (i.e. ionic accessibility) of a CO2 reduction cathode using electrochemical techniques and cell configurations that avoid the complexities related to co-electrolysis (oxygen evolution reaction at anode).

Abstract: Disclosed herein are systems and methods for measuring integrated circuit activity via spatial resolution of optically detected magnetic resonance (ODMR) of nitrogen-vacancies (NV) in diamond. A quantum diamond microscope (QDM) can be used to capture a series of images of the fluorescence of NV centers present in diamond as a function of an external microwave field. An IC device placed adjacent to the diamond of the QDM will impact the fluorescence of the NV center, and this magnetic field-dependent fluorescence can be measured and used to generate a map of the magnetic field of the IC device.

Abstract: Vehicles and related systems and methods are provided for controlling a vehicle in an autonomous operating mode. One method involves obtaining navigation information for a route for the vehicle from a navigation system, transforming the navigation information into data points defining an upcoming trajectory of the route, mapping the data points to a corresponding mapped set of lane segments encompassing one or more of the data points, assigning lane preference indicia to the mapped set of lane segments, and autonomously operating one or more actuators onboard the vehicle to laterally maneuver the vehicle into one or more lanes at respective longitudinal positions along the route corresponding to one or more lane segments of the mapped set of lane segments in a manner that is influenced by the lane preference indicia assigned to the lane segments.

Abstract: A device which illuminates internal tissue and organs of a patient is described. The illumination member includes an array of light-emitting diodes (“LEDs”). The arrangement of the array depends on the configuration of the device and the procedure for which the device is being used. In all cases, the illumination member is used to illuminate relevant organs or structures in the body in order to increase visibility during surgical procedures. The LED array reduces the potential for inadvertent injury to internal structures for procedures located throughout the body. These procedures include those involving the reproductive organs of males and females, gastric and bariatrics, and other structures in the abdomen.

Abstract: Methods and systems of displaying substring pairs where visual demarcations delineate adjacent substring pairs from each other. The method may comprise receiving a plurality of the primary substrings, a plurality of the secondary substrings, and a plurality of visual demarcations, displaying, on an electronic display, the primary substrings and the secondary substrings arranged into substring pairs, and one of the visual demarcations in each of the correspondence areas. Additional desired visual effects may be achieved through the use of specific demarcations, demarcation placements, and substring modifications.