Patents by Inventor David A. B. Miller

David A. B. Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240158368
    Abstract: Pyrrolidine main protease inhibitors are described that are effective as antiviral compounds.
    Type: Application
    Filed: October 12, 2023
    Publication date: May 16, 2024
    Applicant: AbbVie Inc.
    Inventors: David A. Degoey, Michael R. Schrimpf, David J. Hardee, Jacob Ludwig, Eric R. Miller, Timothy R. Hodges, Alberto Munoz, Sarah J. Perlmutter, Huan-Qiu X. Li, Alvin Jang, Elizabeth L. Noey, Gregory A. Gfesser, Edgars Jecs, Robert G. Schmidt, Justin D. Dietrich, Xenia B. Searle, Boguslaw P. Nocek, Andrew Bogdan
  • Publication number: 20240147243
    Abstract: An embodiment includes a method to increase the efficiency of security checkpoint operations. A security checkpoint kiosk serves as a Relying Party System (RPS). The RPS establishes a secure local connection between the RPS and a User Mobile-Identification-Credential Device (UMD). The RPS sends a user information request to the UMD, via the secure local connection, seeking release of user information associated with a Mobile Identification Credential (MIC). The RPS obtains authentication of the user information received in response to the user information request. The RPS retrieves user travel information based on the user information. The RPS determines that the user travel information matches the user information. When the user travel information matches the user information, the RPS approves the user to proceed past the security checkpoint kiosk.
    Type: Application
    Filed: January 4, 2024
    Publication date: May 2, 2024
    Inventors: Haya Iris VILLANUEVA GAVIOLA, Gianpaolo FASOLI, Vinay GANESH, Irene M. GRAFF, Martijn Theo HARING, Ahmer A. KHAN, Franck Farian RAKOTOMALALA, Gordon Y. SCOTT, Ho Cheung CHUNG, Antonio ALLEN, Mayura Dhananjaya DESHPANDE, Thomas John MILLER, Christopher SHARP, David W. SILVER, Policarpo B. WOOD, Ka YANG
  • Publication number: 20240115701
    Abstract: Provided herein are methods of separating host cell lipases from a production protein in chromatographic processes and methods of improving polysorbate-80 stability in a production protein formulation by separating host cell lipases from the production protein using chromatographic processes. Also provided herein are compositions comprising antibodies or antigen binding fragments thereof that bind to cytotoxic T lymphocyte associated antigen 4 (CTLA4). In another aspect, such compositions further comprise a reduced level of host cell proteins and/or increased level of polysorbate-80 (PS-80) stability.
    Type: Application
    Filed: September 18, 2020
    Publication date: April 11, 2024
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Rebecca A. Chmielowski, Francis K. Insaidoo, Justin B. Miller, David J. Roush, Darshini Shah, John P. Welsh
  • Patent number: 11950101
    Abstract: An embodiment includes a method to increase the efficiency of security checkpoint operations. A security checkpoint kiosk serves as a Relying Party System (RPS). The RPS establishes a secure local connection between the RPS and a User Mobile-Identification-Credential Device (UMD). The RPS sends a user information request to the UMD, via the secure local connection, seeking release of user information associated with a Mobile Identification Credential (MIC). The RPS obtains authentication of the user information received in response to the user information request. The RPS retrieves user travel information based on the user information. The RPS determines that the user travel information matches the user information. When the user travel information matches the user information, the RPS approves the user to proceed past the security checkpoint kiosk.
    Type: Grant
    Filed: August 10, 2021
    Date of Patent: April 2, 2024
    Assignee: Apple Inc.
    Inventors: Haya Iris Villanueva Gaviola, Gianpaolo Fasoli, Vinay Ganesh, Irene M. Graff, Martijn Theo Haring, Ahmer A. Khan, Franck Farian Rakotomalala, Gordon Y. Scott, Ho Cheung Chung, Antonio Allen, Mayura Dhananjaya Deshpande, Thomas John Miller, Christopher Sharp, David W. Silver, Policarpo B. Wood, Ka Yang
  • Publication number: 20240089197
    Abstract: Methods and apparatus for interfaces to manage inter-regional connectivity for direct network peerings. A system may include a connectivity coordinator, a first resource collection in a first geographical zone and a second resource collection in a second geographical zone. The coordinator implements a programmatic interface defining connectivity operations. The coordinator receives a request via the interface to establish a logically isolated network path to the second resource collection on behalf of a client that has a dedicated physical link set up to connect to the first resource collection. In response to the request, the coordinator performs one or more configuration operations to enable traffic to flow from the client's network to the second resource collection over a logically isolated network path using the dedicated physical link.
    Type: Application
    Filed: September 12, 2023
    Publication date: March 14, 2024
    Applicant: Amazon Technologies, Inc.
    Inventors: Andrew J. Doane, Kevin Christopher Miller, David B. Lennon
  • Patent number: 11929466
    Abstract: Provided herein are energy storage devices. In some cases, the energy storage devices are capable of being transported on a vehicle and storing a large amount of energy. An energy storage device is provided comprising at least one liquid metal electrode, an energy storage capacity of at least about 1 MWh and a response time less than or equal to about 100 milliseconds (ms).
    Type: Grant
    Filed: May 11, 2023
    Date of Patent: March 12, 2024
    Assignee: Ambri Inc.
    Inventors: David J. Bradwell, David A. H. McCleary, Gregory A. Thompson, Allan Blanchard, Jeffrey B. Miller, Ronald Teel, William B. Langhauser, Alexander W. Elliott, Donald R. Sadoway, Michael J. McNeley, Ian Redfern
  • Publication number: 20240004417
    Abstract: An apparatus for combined digital and optical processing of a cryptocurrency data block includes a digital processor that computes a hash vector from the cryptocurrency data block; a laser and splitter that produces optical input signals; optical modulators that binary phase-shift key modulate the optical input signals based on the hash vector; a photonic matrix multiplier circuit that performs an optically perform a discrete matrix-vector product operation on the modulated optical input signals to produce optical output signals, where the discrete matrix-vector product operation is defined by matrix elements limited to K discrete values, where 2?K?17; and photodetectors and comparators that perform optoelectronic conversions of the optical output signals to produce corresponding digital electronic output signals. The digital processor performs a second hash computation on an XOR result between the digital electronic output signals and the hash vector to produce a proof of work result.
    Type: Application
    Filed: March 25, 2023
    Publication date: January 4, 2024
    Inventors: Sunil K. Pai, David A.B. Miller, Olav Solgaard, Shanhui Fan, Michael Dubrovsky, Bogdan Penkovsky, Maynard Marshall Ball, JR.
  • Patent number: 11828090
    Abstract: A hoop lock including a shackle and a crossbar, with the shackle having a pair of legs extending from a body portion, and each of the legs having a foot including a tip with a non-circular cross-section. The cross-bar includes a housing having a pair of foot-receiving openings and a pair of tip-receiving openings substantially aligned with foot-receiving openings. The tip-receiving openings are configured to matingly engage the tips such that the tips are rotationally coupled to the housing.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: November 28, 2023
    Assignee: Schlage Lock Company LLC
    Inventors: Daniel H. Kindstrand, Hassan Charan Kumar, Manjunatha Ramakrishna, David B. Miller
  • Patent number: 11745815
    Abstract: Lock mounting assemblies are disclosed for storing and mounting a locking apparatus to a transportation device. The mounting assemblies include one or more straps or connectors for securing the mounting assembly to the transportation device. The mounting assemblies having a structure to securely retain the locking apparatus on the transportation device and provide easy access to and release of the locking apparatus from the mounting assembly.
    Type: Grant
    Filed: September 7, 2021
    Date of Patent: September 5, 2023
    Assignee: Schlage Lock Company LLC
    Inventors: Robert D. Zuraski, Daniel H. Kindstrand, David B. Miller, Alison J. Donlan, Donald H. Warren, Michael Tintsman, John D. Fiegener, Caitlin A. Thompson, Gregory R. Meyer, Thomas A. Gernetzke, William J. Vespa, Matthew R. Gill, William Liteplo
  • Publication number: 20220327369
    Abstract: Improved training of optical neural networks is provided. In one example: 1) we choose input and target vectors, we program those into an input vector generator and a measurement unit, respectively, we turn on the optical input source power, and we monitor the electrical signal representing the cost function. 2) we can then modulate two or more controllable elements inside the optical network at different frequencies and look for the size and sign of the corresponding distinct AC variations in the measured cost function, simultaneously giving us the gradients with respect to each element.
    Type: Application
    Filed: September 9, 2020
    Publication date: October 13, 2022
    Inventors: Shanhui Fan, Tyler William Hughes, David A.B. Miller, Sunil K. Pai, Olav Solgaard, Ian A.D. Williamson
  • Publication number: 20220169327
    Abstract: Lock mounting assemblies are disclosed for storing and mounting a locking apparatus to a transportation device. The mounting assemblies include one or more straps or connectors for securing the mounting assembly to the transportation device. The mounting assemblies having a structure to securely retain the locking apparatus on the transportation device and provide easy access to and release of the locking apparatus from the mounting assembly.
    Type: Application
    Filed: September 7, 2021
    Publication date: June 2, 2022
    Inventors: Robert D. Zuraski, Daniel H. Kindstrand, David B. Miller, Alison J. Donlan, Donald H. Warren, Michael Tintsman, John D. Fiegener, Caitlin A. Thompson, Gregory R. Meyer, Thomas A. Gernetzke, William J. Vespa, Matthew R. Gill, William Liteplo
  • Patent number: 11144821
    Abstract: The disclosed embodiments relate to a system that implements a photonic neuron. This photonic neuron includes: an excitatory-input photo detector that converts an optical excitatory input signal into a corresponding electrical excitatory input signal; and an inhibitory-input photo detector that converts an optical inhibitory input signal into a corresponding electrical inhibitory input signal. It also includes an electrical neuron that receives the electrical excitatory and inhibitory input signals, and generates an electrical output signal, which includes periodic voltage spikes that are triggered by integration of the electrical excitatory and inhibitory input signals. Finally, the photonic neuron includes a light-emitting output device, which converts the electrical output signal into a corresponding optical output signal.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: October 12, 2021
    Assignee: The Regents of the University of California
    Inventors: Sung-Joo Ben Yoo, David A. B. Miller
  • Publication number: 20210277688
    Abstract: A hoop lock including a shackle and a crossbar, with the shackle having a pair of legs extending from a body portion, and each of the legs having a foot including a tip with a non-circular cross-section. The cross-bar includes a housing having a pair of foot-receiving openings and a pair of tip-receiving openings substantially aligned with foot-receiving openings. The tip-receiving openings are configured to matingly engage the tips such that the tips are rotationally coupled to the housing.
    Type: Application
    Filed: October 20, 2020
    Publication date: September 9, 2021
    Inventors: Daniel H. Kindstrand, Hassan Charan Kumar, Manjunatha Ramakrishna, David B. Miller
  • Patent number: 11110980
    Abstract: Lock mounting assemblies are disclosed for storing and mounting a locking apparatus to a transportation device. The mounting assemblies include one or more straps or connectors for securing the mounting assembly to the transportation device. The mounting assemblies having a structure to securely retain the locking apparatus on the transportation device and provide easy access to and release of the locking apparatus from the mounting assembly.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: September 7, 2021
    Assignee: Schlage Lock Company LLC
    Inventors: Robert D. Zuraski, Daniel H. Kindstrand, David B. Miller, Alison J. Donlan, Donald H. Warren, Michael Tintsman, John D. Fiegener, Caitlin A. Thompson, Gregory R. Meyer, Thomas A. Gernetzke, William J. Vespa, Matthew R. Gill, William Liteplo
  • Patent number: 10877287
    Abstract: Universal linear components are provided. In general, a P input and Q output wave combiner is connected to a Q input and R output wave mode synthesizer via Q amplitude and/or phase modulators. The wave combiner and wave mode synthesizer are both linear, reciprocal and lossless. The wave combiner and wave mode synthesizer can be implemented using waveguide technology. This device can provide any desired linear transformation of spatial modes between its inputs and its outputs. This capability can be generalized to any linear transformation by using representation converters to convert other quantities to spatial mode patterns. The wave combiner and wave mode synthesizer are also useful separately, and can enable applications including self-adjusting mode coupling, optimal multi-mode communication, and add-drop capability in a multi-mode system. Control of the wave combiner and wave mode synthesizer can be implemented with single-variable optimizations.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: December 29, 2020
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventor: David A. B. Miller
  • Patent number: 10808428
    Abstract: A hoop lock including a shackle and a crossbar, with the shackle having a pair of legs extending from a body portion, and each of the legs having a foot including a tip with a non-circular cross-section. The cross-bar includes a housing having a pair of foot-receiving openings and a pair of tip-receiving openings substantially aligned with foot-receiving openings. The tip-receiving openings are configured to matingly engage the tips such that the tips are rotationally coupled to the housing.
    Type: Grant
    Filed: March 21, 2019
    Date of Patent: October 20, 2020
    Assignee: Schlage Lock Company LLC
    Inventors: Daniel H. Kindstrand, Hassan Charan Kumar, Manjunatha Ramakrishna, David B. Miller
  • Patent number: 10711491
    Abstract: Portable lock mounting assemblies including straps or connectors for securing each assembly to a bicycle or the like. Each mounting assembly having a structure defining a retaining assembly to securely retain a lock and easily release the lock from the mounting assembly.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: July 14, 2020
    Assignee: Schlage Lock Company LLC
    Inventors: Robert D. Zuraski, Daniel H. Kindstrand, Donald H. Warren, John D. Fiegener, David B. Miller
  • Patent number: 10706247
    Abstract: A camera box for capturing and processing bar code images on the bottom ends of laboratory tubes in a laboratory tube rack of standard size with laboratory tube compartments each having a bottom aperture utilizing a smart phone camera, the camera box including a housing with a top deck and sides with one side having a lower side opening, the top deck of the housing having an opening sized to view the underside of a rack when the tube rack is seated on the top deck over the opening and including a camera tray that supports a smart phone camera, wherein the side opening of the camera box housing is sized to receive the camera tray and a supported smart phone camera into the housing under the housing opening and a rack with at least one laboratory tube seated on the top deck, wherein on activation of the smart phone camera, an image of the underside of the rack and the barcode of any laboratory tube in the rack is captured and processed.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: July 7, 2020
    Inventor: David B. Miller
  • Publication number: 20200180716
    Abstract: Lock mounting assemblies are disclosed for storing and mounting a locking apparatus to a transportation device. The mounting assemblies include one or more straps or connectors for securing the mounting assembly to the transportation device. The mounting assemblies having a structure to securely retain the locking apparatus on the transportation device and provide easy access to and release of the locking apparatus from the mounting assembly.
    Type: Application
    Filed: December 10, 2019
    Publication date: June 11, 2020
    Inventors: Robert D. Zuraski, Daniel H. Kindstrand, David B. Miller, Alison J. Donlan, Donald H. Warren, Michael Tintsman, John D. Fiegener, Caitlin A. Thompson, Gregory R. Meyer, Thomas A. Gernetzke, William J. Vespa, Matthew R. Gill, William Liteplo
  • Patent number: 10533004
    Abstract: A method of preparing a compound of Formula (I) or a pharmaceutically acceptable salt thereof: comprises: (a) reacting Compound (1): or a pharmaceutically acceptable salt thereof with Compound (2): in the presence of water, an organic solvent, a base, and a transition metal catalyst to generate a compound of Formula (I) or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 9, 2017
    Date of Patent: January 14, 2020
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Luc J. Farmer, Michael John Boyd, David B. Miller, Jr., Valerie Ann Cwynar