Abstract: The ultrasonic inspectability of a supplied part out of which a final component is to be machined is determined by following a set of inspection rules for ultrasonic inspection of the supplied part. The rules determine which parts of the polygon cannot be inspected by a scan at a given ultrasound beam angle (typical beam angles are 0°, +20° and ?20° relative to the perpendicular direction to the edge) along a given edge of the polygon.

Abstract: A system and method for subscriber aware network monitoring is provided. The method includes: determining subscriber and session data, wherein the subscriber has a non-unique IP (Internet Protocol) address; retrieving identifying data from a packet; and comparing the identifying data with the determined subscriber and session data to determine the subscriber associated with the packet. The system includes: at least one network probe configured to determine subscriber and session data, wherein the subscriber has a non-unique Internet Protocol (IP) address; at least one traffic probe configured to retrieve identifying data from a packet; and a processing module configured to compare the identifying data with the stored subscriber and session data to determine the subscriber associated with the packet.

Abstract: The present invention relates to the provision of novel immunogens comprising an antigenic IgE peptide preferably linked to an immunogenic carrier for the prevention, treatment or alleviation of IgE-mediated disorders. The invention further relates to methods for production of these medicaments, immunogenic compositions and pharmaceutical compositing thereof and their use in medicine.

Abstract: The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.

Abstract: An apparatus for aligning non-synchronous input data streams received in the apparatus, the apparatus comprising an analog to digital converter arrangement for digitizing the data streams into a plurality of sequences of samples; and a synchronization processing arrangement for generating alignment pulses for each sequence of the plurality of sequences of samples, for arranging each sequence of samples with respect to the alignment pulses for the sequence and for synchronization the delivery of said plurality of sequences of samples to a common processor with respect to the respective alignment pulses. The synchronization processing arrangement may comprise a processing chain for each antenna feed of said plurality of antenna feeds and each processing chain may comprise an alignment pulse generator for generating an alignment pulse for the sequence of samples corresponding to the processing chain. The input data streams may be received by a plurality of antenna feeds.

Abstract: There is provided a system and method for diverting established communication sessions, which includes: receiving at least one packet from a communication session; determining the state of the communication session; if the state of the communication session is diverted, bridging the at least one packet to a service chain; if the state of the communication session has been prohibited from being diverted, forwarding the at least one packet to an endpoint; and otherwise, if the state of the communication session is a state prior to the divert decision, saving the at least one packet and determining whether the communication session is a candidate to be diverted to the service chain.

Abstract: The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.

Abstract: The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.

Abstract: A method of manufacturing an article by hot pressing and ultrasonically inspecting the article comprises forming and filling a canister with powder material and evacuating and sealing the canister. Heat and pressure are applied to the canister to consolidate the powder material to form the article. The article within the canister is ultrasonically inspected by moving a transducer over the whole of the canister. The position of an interface between the article and the canister, and the thickness of the canister, at each position on the surface of the canister and if there are defects within the article are determined. The canister is then removed from the article by machining the canister using a machining tool, the movement of the tool is controlled such that at each position of the canister the tool removes the determined thickness of the canister for the corresponding position on the surface of the canister.

Abstract: The present invention relates in part to nicotine-derived hapten-carrier conjugates of the formula (III): wherein m, n, W, -(spacer)-, X* and Y are as defined in the description. In certain embodiments, said nicotine-derived hapten-carrier conjugates can be used to prepare vaccines for the treatment and/or prevention of nicotine addiction.

Abstract: A computer-implemented system and method for the processing and presentation of flight tracking data from a number of sources, with at least one source include a user access restriction, is disclosed. Substantially real-time flight tracking data is received over a digital network from a number of different sources and is stored in at least a database. Various determined flight paths are stores for a single flight based upon the number of flight data sources contributing data regarding that flight. Upon receiving a query from a user, the user's access with respect to the available data providers in retrieved and the best flight for the selected flight which is determined only from data that the requested user is authorized to access is presented. In one form, the results may be presented to the user in the form of digital map having an aircraft image and historical flight path shown.

Abstract: A computer-implemented system and method for the collection, filtering, and transmission of aviation information is disclosed. A plurality of flight information is received over a digital network at various remote locations, and the data is filtered prior to transmission to a central database for presentation and use. The database includes aviation information. The method of filtration is dynamically updated as to information concerning a specific flight based on one characteristic of the flight. As to aircraft being tracked, a determination is made as to which receiver should relay collected data, and that determination is periodically revised, such as to minimize transmission costs and maximize signal quality as aircraft positions change. Once the information is located in the central database, it is suitable for use in responding to user requests for flight tracking information is association with at least one identified flight.

Abstract: The present invention relates to imidazopyridazine derivatives. More particularly, it relates to 4-(biphenyl-3-yl)-7H-imidazo[4,5-c]pyridazine derivatives of formula (I): and pharmaceutically acceptable salts thereof, wherein R1, R2, R3, R4 and R5 are as defined in the description. The imidazopyridazine derivatives of the present invention modulate the activity of the GABAA receptor. They are useful in the treatment of a number of conditions, including pain.

Abstract: The present disclosure provides a system and a method for managing network traffic. The traffic management system has a quality of experience (QoE) measurement module configured to monitor a QoE metric in real-time. A control module is configured to periodically receive the QoE metric and determine a traffic management action based on the QoE metric. A traffic management module is configured to apply the traffic management action to the network traffic.

Abstract: The present invention relates to novel 2,3,4-substituted 5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridine compounds and pharmaceutically acceptable salts thereof, to compositions containing such compounds and to the use of such compounds as inhibitors of HIV replication.

Abstract: A system and method for automatically configuring a network so that each switch in the network is aware of the Multiple Spanning Tree Instances (MSTI) of each other switch and the Virtual Local Area Network (VLAN) that each switch uses. This is achieved through the use of controllers connected to each switch. A master switch is elected and the master switch monitors messages to determine if a switch should be using an alternative MISTI. If so, the master switch instructs a switch to use an alternative MSTI. Either a switch or a node connected to the switch may determine which VLAN to use in sending messages, subject to configuration from the controller of the master switch. Messages are periodically sent by each controller to educate other controllers to aid in learning which node is part of a group connected to a switch, the switch in turn connected to a controller.

Abstract: A system and method for subscriber aware network monitoring is provided. The method includes: determining subscriber and session data, wherein the subscriber has a non-unique IP (Internet Protocol) address; retrieving identifying data from a packet; and comparing the identifying data with the determined subscriber and session data to determine the subscriber associated with the packet. The system includes: at least one network probe configured to determine subscriber and session data, wherein the subscriber has a non-unique Internet Protocol (IP) address; at least one traffic probe configured to retrieve identifying data from a packet; and a processing module configured to compare the identifying data with the stored subscriber and session data to determine the subscriber associated with the packet.

Abstract: Techniques are disclosed to transmit arbitrarily large data units for transaction processing in a networked environment. A request is received to store a data unit of a size exceeding an allocated memory address space of a transaction gateway component of the networked environment. A predefined store function, provided by a repository interface component, is invoked to store the data unit to a data repository component of the networked environment and without segmenting the data unit. A repository handle of the stored data unit is identified. A predefined load function, provided by the repository interface component, is invoked to load a portion of the stored data unit, based on the identified repository handle, where the portion is smaller than the stored data unit.

Abstract: According to one aspect of the present disclosure, a method and technique for link optimization for callout request messages is disclosed. The method includes: monitoring a plurality of different time-based parameters for each of a plurality of links between a communication pipe of a host system and one or more service systems, the links used to send and receive callout request messages between one or more applications running on the host system and the services systems that process the callout request messages, the time-based parameters associated with different stages of callout request message processing by the communication pipe and the service systems; assessing a performance level of each of the plurality of links based on the time-based parameters; and dynamically distributing the callout request messages to select links of the plurality of links based on the performance assessment.

Abstract: The present invention relates to novel 2,3,4-substituted 5,6,7,8-tetrahydro[1]benzothieno[2,3-b]pyridine compounds and pharmaceutically acceptable salts thereof, to compositions containing such compounds and to the use of such compounds as inhibitors of HIV replication.