Abstract: A head unit system for controlling motion of an object includes a secondary object sensor and a head unit device that includes a shear thickening fluid (STF) and a chamber configured to contain a portion of the STF. The chamber further includes an alternative reservoir and a piston compartment. The head unit system further includes a piston housed at least partially radially within the piston compartment. The piston includes a piston bypass to control flow of the STF between opposite sides of the piston. The chamber further includes a set of fluid flow sensors and a set of fluid manipulation emitters to control the flow of the STF to cause selection of one of a variety of shear rates for the STF within the chamber.

Abstract: A head unit system for controlling motion of an object includes a set of secondary object sensors and head unit devices that include shear thickening fluid (STF) and a chamber configured to contain a portion of the STF. The chamber further includes a front channel and a back channel. The head unit system further includes a piston housed at least partially radially within the piston compartment and separating the back channel and the front channel. The piston includes a first piston bypass and a second piston bypasses to control flow of the STF between opposite sides of the piston. The chamber further includes a set of fluid flow sensors and a set of fluid manipulation emitters to control the flow of the STF to cause selection of one of a variety of shear rates for the STF within the chamber.

Abstract: A method of manufacturing a flowable and dispersible powder includes solubilizing a lipophilic substance in a terpene to form a mixture and treating the mixture to form a nanoemulsion dispersed in an aqueous solution. The aqueous solution includes at least one functional excipient. The nanoemulsion is then spray dried, thereby evaporating first the aqueous portion and then the terpene to form a dry powder formed from solid particles comprising the lipophilic substance.

Abstract: The present disclosure relates to a cover for at least one antenna emitting or sensing electromagnetic radiation in at least one first frequency band, the cover includes at least one first surface facing the antenna and at least one second surface averted to the antenna, where the cover includes at least one substrate being transmissible for electromagnetic radiation and at least one first coating covering the substrate in at least one first area, the first coating being transmissible for electromagnetic radiation of at least the first frequency band, whereas the first coating is reflective for electromagnetic radiation falling onto the second surface and having a frequency within at least one second frequency band.

Abstract: A head unit system for controlling an object includes a head unit device that include shear thickening fluid (STF) and a chamber configured to contain the STF. The chamber further includes a set of gates between a front channel and a back channel. The set of gates includes a bypass opening set. The head unit device further includes a cupped piston housed at least partially radially within the chamber. The set of gates is configured to control flow of the STF between the front channel and the back channel to control rotational movement of the object.

Abstract: An intake air circuit is structured to transmit intake air from a turbocharger compressor to an intake manifold of an engine. A charge air cooler (“CAC”), a bypass line, and a bypass heater are each positioned along the intake air circuit in parallel with each other. A first control valve is structured to controllably divert the intake air around the CAC. A second control valve is structured to controllably divert the intake air around at least one of the bypass line and the bypass heater. A controller operatively coupled to each of the engine, and the first and second control valves is structured to control each of the first and second control valves to cause the intake air to flow along a determined desired flow path based on each of measured ambient temperature and measured engine load.

Abstract: A panel for attenuating noise is disclosed comprising a face skin having a first inner surface, a base skin having a second inner surface, a cellular core connected to and forming a plurality of cells between the face skin and the base skin, wherein the cellular core is defined by a cell structure having a plurality of cell walls extending between the face skin and the base skin defining each of the plurality of cells and a septum disposed within each of the plurality of cells, the septum defining an upper chamber proximate the face skin and a lower chamber proximate the base skin, wherein the face skin comprises a plurality of perforations fully through the face skin and in fluid communication with the upper chamber.

Abstract: A head unit system for controlling an object includes a head unit device that include shear thickening fluid (STF) and a chamber configured to contain the STF. The chamber further includes a set of gates between a front channel and a back channel. The set of gates includes a bypass opening set. The head unit device further includes a cupped piston housed at least partially radially within the chamber. The set of gates is configured to control flow of the STF between the front channel and the back channel to control movement of the object.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Disclosed herein is a data storage device. A data port transmits data between a host computer system and the data storage device. A non-volatile storage medium stores encrypted user content data and a cryptography engine uses a cryptographic key to decrypt the encrypted user content data stored on the storage medium in response to a request from the host computer system. An access controller receives a request from a manager device to initialize the data storage device. The controller generates the cryptographic key, generates a manager key configured to provide manager access for the manager device and provide access to the cryptographic key, and stores, on a data store, authorization data indicative of the manager key and accessible based on a private key stored on the manager device.

Abstract: Provided herein are D domain containing polypeptides that specifically bind targets of interest, as are nucleic acids encoding the D domain containing polypeptides, vectors containing the nucleic acids and host cells containing the nucleic acids and vectors. Also provided herein are methods of making and using the D domain containing polypeptides, nucleic acids, vectors and host cells, for example, but not limited to, in diagnostic and therapeutic applications. Also provided herein are multi-functional chimeric antigen receptor (CAR)-based compositions and Adapters and their use in methods of directing immune responses to target cells. In some embodiments, the methods include the use of a CAR expressing cell in combination with an Adapter. The Adapter confers the ability to modulate, alter, and/or direct CAR expressing cell-mediated immune response in vitro and in vivo.

Abstract: Various embodiments provide a sterilisation apparatus for sterilising a channel of a surgical scoping device. The apparatus includes: a gas supply having a conduit to deliver an ionisable gas to the channel of the surgical scoping device; and, a sterilisation instrument, separate from the gas supply and the conduit, configured to be inserted through the channel of a surgical scoping device. The sterilisation instrument includes an elongate probe. The elongate probe includes: a transmission line for conveying radiofrequency (RF) electromagnetic (EM) energy and/or microwave EM energy; and, a probe tip connected at the distal end of the transmission line for receiving the RF and/or microwave EM energy, the probe tip comprising an electrode assembly configured to produce an electric field from the received RF and/or microwave frequency EM energy to generate a plasma of the ionisable gas delivered to the channel from the gas supply.

Abstract: The present invention provides binding molecule or molecules that are able to multimerise CD45 to induce cell death of a cell expressing CD45 without also inducing significant cytokine release. For example, the invention provides antibodies against CD45, wherein the antibodies comprise at least two different paratopes each specific for a different epitope of CD45. The antibodies may be used to cross-link CD45 on the surface of cells. The antibodies may be used in a variety of therapeutic ways including to deplete cells, for example prior to cell transplantation.

Abstract: The present invention relates to a method of treating cognitive impairment in a patient in need thereof by administering Compound (I), a stimulator of soluble guanylate cyclase (sGC) at certain dosages either alone or in combination therapy.

Abstract: In embodiments, a wearable cardiac defibrillation (WCD) system includes one or more flexible ECG electrodes. The WCD system may have a support structure that is dimensioned to be worn so as to press the electrodes towards the body of the patient. The electrodes may be made from appropriate material so as to flex in order to match a contour of the body of the patient. An advantage over the prior art is that the flexible electrode may make better electrical contact with the patient's skin, and therefore provide a better ECG signal for the WCD system to perform its diagnosis.

Abstract: The present teachings generally relate to a frame assembly comprising a connector device and a method for fabricating the same. The frame assembly comprises a member (12) and one or more connector devices (14A, 14B) coupled to and supporting opposing ends the member. Each of the one or more connector devices comprise a base member; a first projection extending from a first side of the base member, the projection defining a cavity; an end channel situated within the cavity and extending around a perimeter of the projection proximate the base member; a port extending from the end channel on the first side of the base member to a second side of the base member, the second side being in opposing relationship to the first side; and an adhesive, introduced via the port, situated within the end channel. Opposing ends of the member are situated within each of the cavities of two connector devices, respectively, and in contacting relationship with the adhesive.

Abstract: Aspects described herein may allow for authenticating a user by generating a customized set of authentication questions based on spending patterns that are automatically detected and extracted from user data. The user data may include transaction data collected over a period of time that may indicate the types of merchants that a user frequently transacts with. By automatically detecting user patterns that correspond to user behavior over a period of time, an authentication system may be able to generate authentication questions about those spending patterns that are easily answerable to an authentic user but difficult to guess or circumvent for any other user.

Abstract: A system for interfacing predetermined services to a user at a fixed location includes a processing platform running an operating system. The system further includes a data store for storing configuration information for enabling the operating system to interface with available physical system resources through the physical system resource interface associated therewith. A communication resource for interfacing with the operating system allows communication of the operating system with a central office for downloading configuration information to selectively enable ones of the available physical system resources to interface with the operating system through associated ones of the physical system resource interfaces in accordance with the configuration information and the predetermined service selected by a user. A plurality of configurations is stored in the data store, and each is associated with a predetermined service and one or more of the available physical system resources.

Abstract: Direct-bonded native interconnects and active base dies are provided. In a microelectronic architecture, active dies or chiplets connect to an active base die via their core-level conductors. These native interconnects provide short data paths, which forgo the overhead of standard interfaces. The system saves redistribution routing as the native interconnects couple in place. The base die may contain custom logic, allowing the attached dies to provide stock functions. The architecture can connect diverse interconnect types and chiplets from various process nodes, operating at different voltages. The base die may have state elements for drive. Functional blocks aboard the base die receive native signals from diverse chiplets, and communicate with all attached chiplets. The chiplets may share processing and memory resources of the base die. Routing blockages are minimal, improving signal quality and timing. The system can operate at dual or quad data rates.

Abstract: A network interface device having a hardware module comprising a plurality of processing units. Each of the plurality of processing units is associated with its own at least one predefined operation. At a compile time, the hardware module is configured by arranging at least some of the plurality of processing units to perform their respective at least one operation with respect to a data packet in a certain order so as to perform a function with respect to that data packet. A compiler is provide to assign different processing stages to each processing unit. A controller is provided to switch between different processing circuitry on the fly so that one processing circuitry may be used whilst another is being compiled.