Abstract: Tools and techniques for asynchronous database updates between client applications and search utilities are provided. These tools may receive indications of updates occurring within a workspace in which two or more users are collaborating. Updates to the collaborative workspace may be committed to a collaboration database maintained internally by a collaboration application. The tools may generate request to commit these updates to a search utility, so that the updates are searchable. The search utility maintains a search database that is decoupled from and operates independently of the collaboration database. The tools may increment a notification counter associated with the collaborative workspace, with the notification counter tracking how many requests to commit updates are pending. Finally, the tools may send the request to commit the update to the search database asynchronously with respect to the collaboration database.

Abstract: Currency and consistency requirements are specified as part of a query against a database that may contain replicated data that is updated asynchronously and therefore may not be completely up to date. The database system constructs query execution plans that include an input selection operator that verifies the currency of a replica and selects a subplan using the replica for execution only when the replica meets the query's currency constraints. It checks possible query execution plans at construction time against the query's consistency constraints and any plans that may produce a result not meeting the consistency constraints are rejected. In this way, the query result is guaranteed to satisfy the query's currency and consistency requirements.

Abstract: A computer program product that provides a graphical user interface for configuring communication information for multiple network service providers on a computer system. The program product is operable to display a network communication scene that includes edit windows and selectable options for a user to view, enter, remove, and modify configuration information for at least one network service provider, and allows the user to enter information for establishing communication with the same network service provider using at least two different communication mediums, and from several different geographical locations.

Abstract: A query translation system and method for processing a streaming language query on existing or stored data. The streaming language query is applied against a data stream log by first translating the streaming language query into a database management system query (such as a SQL query) and then applying the translated streaming language query against the data stream log. Embodiments of the query translation system and method include a bitemporal converter that converts a bitemporal data stream log into a canonical history table format. Once in this format, embodiments of the query translation system and method translate a streaming language query into a SQL query. A categorization of each of the streaming operators that make up the streaming language query is performed to determine which translation technique to use. In general, one of three general translation techniques is used based on these categorizations of the streaming operators.

Abstract: An interactive, handheld apparatus is provided. The apparatus includes a housing, a display screen on the housing, an electronic position location system, a stylus for selecting images on the display screen, a directional control pad on the housing and a memory device. The electronic position location system includes a processor that is capable of determining a location of a selected region of the display screen. The memory device includes computer code for an educational game and is operatively coupled to the processor.

Abstract: An interactive, handheld apparatus is provided. The apparatus includes a housing, a display screen on the housing, an electronic position location system, a stylus for selecting images on the display screen, a directional control pad on the housing and a memory device. The electronic position location system includes a processor that is capable of determining a location of a selected region of the display screen. The memory device includes computer code for an educational game and is operatively coupled to the processor.

Abstract: An interactive, handheld apparatus is provided. The apparatus includes a housing, a display screen on the housing, an electronic position location system, a stylus for selecting images on the display screen, a directional control pad on the housing and a memory device. The electronic position location system includes a processor that is capable of determining a location of a selected region of the display screen. The memory device includes computer code for an educational game and is operatively coupled to the processor. A light is associated with the stylus. The light is illuminated to indicate that the stylus is available for use during operation of the educational game.

Abstract: A bead feeder for serially delivering beads to a downstream location comprises a bead supply wheel which rotates about a vertical axis. The bead supply wheel includes a bead supply bowl and a plurality of radially arranged channels below the bowl connected to rotate with the bowl. Discharge openings in the bowl are in alignment with the radially arranged channels to delivery beads to those channels, and a bead receiving pocket is positioned at the outer end of each channel. A transfer wheel picks up beads from the bead receiving pockets and transfers those beads to a delivery wheel by vacuum transfer and release. The delivery wheel serially delivers the beads to the downstream location.

Abstract: Compounds of the Formula: where X1, Ar1, R1, and R2 are as defined herein, and compositions comprising the same. Also provided are methods for using compounds of Formula I in treating p38 mediated disorders in a patient.

Abstract: Compounds of formula I modulate jnk and cdk: or a pharmaceutically acceptable salt thereof, where R, R1, R2, R3, and m are defined herein.

Abstract: Methods of inhibiting a tyrosine kinase wherein said tyrosine kinase is BTK or SYK comprising administering to a patient in need thereof a therapeutically effective amount of a compound according to formula I are disclosed. The compounds are useful for treating auto-immune and inflammatory diseases.

Abstract: Compounds effective as p38 MAP kinase inhibitors, methods of making the compounds, and methods of using the compounds for treatment of p38 MAP kinase-mediated diseases.

Abstract: The present invention provides compounds of the Formula I: wherein R1 is allyl, cycloalkyl, cycloalkylalkyl, or —CH2-alkenyl, X1 is O, NH, N(alkyl), S or —C(?O), Z is N or CH; and R2 and R3 are as defined herein, pharmaceutical compositions comprising same, and methods for their use.

Abstract: Compounds having the formula (I), are useful as p38 kinase inhibitors, wherein R4 and R5 are hydrogen, halogen, cyano, haloalkyl, or haloalkoxy, but are not both hydrogen; R6 and R7 are optional substituents, and Q is a non-aromatic moiety as defined in the specification.

Abstract: The present invention provides compounds of the Formula I and II: wherein R1, R3, W, Z, X1, X2, Ar1, R8 and R9 are as defined herein, and methods and intermediates for their preparation and uses thereof.

Abstract: Compounds having the formula (I) or (II), are useful as p38 kinase inhibitors, wherein R is an optionally substituted alkyl, cycloalkyl, or aryl; R6 is hydrogen or lower alkyl; R7 is hydrogen or a non-interfering substituent, and Q is a non-aromatic moiety as defined in the specification.

Abstract: A computer program product that provides a graphical user interface for configuring communication information for multiple network service providers on a computer system. The program product is operable to display a network communication scene that includes edit windows and selectable options for a user to view, enter, remove, and modify configuration information for at least one network service provider, and allows the user to enter information for establishing communication with the same network service provider using at least two different communcation mediums, and from several different geographical locations.

Abstract: The present invention provides compounds of the Formula I: wherein R1 is alkyl, cycloalkyl, cycloallkylalkyl, or —CH2-alkenyl, X1 is O, NH, N(alkyl), S or —C(?O), Z is N or CH; and R2 and R3 are as defined herein, pharmaceutical compositions comprising same, and methods for their use.

Abstract: A method for determining the dosage regime of a drug suitable for use in the treatment of a neurological condition in a subject, which method comprises typing the SCN1A gene of the subject. The method may be used to determine the dosage regime of an anti-epileptic drug (AED) in a subject. A subject may be treated in accordance with the dosage regime determined using such a method.

Abstract: The present invention discloses compounds corresponding to formula I: wherein A, Z, Z1, Y, R1 and R2 are as defined in the specification, as well as pharmaceutical formulations, methods of making and uses thereof.