Abstract: A live help system provides an intuitive display of help information on a user's graphical user interface. A request is received from a client device for help, and a live help provider interface is initiated at a live help location. Data is acquired regarding a user's location, including data on external devices in the user's location. Indicators are provided to allow the live help provider to point to or otherwise indicate items on the user interface or outside of the user interface. Live help input is captured at the live help provider interface. Instructions are then transmitted to the display of the client device to display live help input, as though the agent were present and interacting with or indicating items on the screen or off the screen.

Abstract: A system for determining peripheral artery disease and method of use for determining the presence or absence of peripheral vascular disease and the severity of the disease in particular vascular segments. The System for determining peripheral artery disease and method of use includes a continuous wave Doppler transceiver which generates a digitized version of quadrature detected stereo audio and is coupleable to a waveform converter and processor. The waveform converter and processor provides filtering, time domain to frequency domain conversion, gain control, and statistical processing of the converted Doppler Stereo audio and is operationally coupled to a display for presenting results to a technician.

Abstract: Methods for analyzing raw electropherogram data are disclosed. Some methods includes extracting color data as a function of time or position from the raw electropherogram data, selecting from the electropherogram one or more peaks that contain color data for a first dye and substantially no color data from other dyes used in electrophoresis. The method also includes determining the color spectrum of the first dye, and using the color spectrum of the first dye to deconvolve the color data of the raw electropherogram data to separate the contributions of each of the dyes to the raw electropherogram data. Systems and apparatus for producing electropherograms are also disclosed.

Abstract: A system for performing capillary electrophoresis of multiple samples comprises a capillary containing a separation medium and having inlet and distal ends and an interrogation region; a power source configured to apply voltages between inlet and distal ends; and logic to cause execution of: applying a first substantially constant forward polarity electrophoresis voltage to the capillary; before all of the first DNA fragments have passed the interrogation region, applying a reverse polarity voltage pulse to the capillary, thereby transporting at least some of the first DNA fragments in the capillary toward the capillary inlet; introducing a second sample to the capillary inlet, the second sample comprising second DNA fragments having a plurality of different sizes; and applying a second substantially constant forward polarity electrophoresis voltage to the capillary to simultaneously perform electrophoresis on the second DNA fragments and the first DNA fragments.

Abstract: A method of making an article bonding a layer of deformable material to a surface of a cartridge body having at least one valve body thereon to seal the at least one valve body, the valve body comprising a valve floor and valve walls comprising upper parts, wherein the valve floor is recessed from the surface and the valve walls extend from the surface to the valve floor, and wherein the valve body comprises walls that are curved or sloped in a direction that is non-normal to the plane defined by the surface; and deforming the layer such that upon release of a force causing the deformation, the layer is in contact with the upper parts of the valve walls and is in spaced from the valve floor so as to bias the valve to an open state.

Abstract: A method of treating cancer or metastasis is provided involving administering at least one oncostatin M (OSM) antagonist to a subject, wherein the subject has been diagnosed with cancer. Administration of an OSM antagonist such as a small molecule pharmaceutical is provided as well as an anti-OSM antibody, an anti-OSM aptamer, and an OSM mRNA antagonist. The OSM antagonists were found to inhibit or prevent tumor cell detachment, progression, proliferation and metastasis in several cancer types.

Abstract: A system comprises an authentication sub-system configured to authenticate a user and a biochemical analysis sub-system configured to perform a biochemical analysis on a biological sample provided to the biochemical analysis sub-system. The system is configured to authenticate a user using the authentication sub-system, instruct an authenticated user to provide a biological sample to the biochemical analysis sub-system, execute a biochemical analysis on a provided biological sample.

Abstract: An apparatus comprises a processing device configured to identify a snapshot lineage comprising snapshots of a given storage volume, the snapshot lineage comprising (i) a local snapshot lineage stored on a storage system and (ii) a cloud snapshot lineage stored on cloud storage of at least one cloud external to the storage system, the cloud snapshot lineage comprising at least a subset of the snapshots of the given storage volume. The processing device is also configured to determine whether the local snapshot lineage is associated with any current local storage volume of the storage system corresponding to the given storage volume and, responsive to determining that the storage system is not associated with any current local storage volume corresponding to the given storage volume, to select a snapshot from the cloud snapshot lineage and recover the selected snapshot to a new local storage volume on the storage system.

Abstract: Disclosed are covering and strapping systems and methods for covering granular product such as grain. An example system includes a cover having a top side and a bottom side, multiple attachment implements directly connected to the top side of the cover, and a plurality of securing straps, each of the securing straps being connected to a respective attachment implement and thereby indirectly connected to the top side of the cover without running through a tunnel. The securing straps can extend beyond the edge of the cover for securing to a structure.

Abstract: One or more techniques and/or systems are disclosed for a transmission that provide power to a front axle, and fits in taller box to provide more room for the transmission. The transmission can comprise a front input shaft that receives rotational power from an engine. A front output shaft is coupled with a front axle to provide the rotational power, conditioned by the transmission, to the front axle. A rear riser gear set can be couple to the rear of the transmission to provide power from the bottom portion of the transmission to a bevel gear set that couples with, and provide rotational power to, a rear axle. In this way, the space between a rear axle centerline and front axle center line can be used by the transmission, allowing for a taller transmission to fit in the chassis.

Abstract: Systems and methods for dynamic computer aided innovation via multidimensional complementary difference recommendation and exploration are disclosed including categorizing a first and second data element in a database with a first attribute and second attribute, respectively, of a first dimension, a dimension being an aspect of a situation, problem, or thing. The first and second data elements are categorized with a first attribute and a second attribute of a second dimension, the second dimension being different from the first dimension. Analyzing the first and second attribute of the first dimension and the first and second attribute of the second dimension to determine a ratio of similarity and dissimilarity; calculating a composite score of the ratio of the first dimension and the ratio of the second dimension; and generating and storing a link between the first and second data element when the composite score is within numerical limits.

Abstract: A support unit for use on an article of furniture includes an adjustable support structure displacably mountable to the article of furniture and a cushion member carried by the support structure. The support structure is configured to be arranged in a first orientation relative to the article of furniture for enabling the cushion member to adopt a first position relative to the article of furniture and in a second orientation (46) relative to the article of furniture for enabling the cushion member to adopt a second position relative to the article of furniture.

Abstract: Certain aspects of the present disclosure generally relate to an adaptive combination power supply circuit. The adaptive combination power supply circuit may be capable of switching between performing as a three-level buck converter and as a divide-by-two charge pump. One example power supply circuit generally includes a first transistor; a second transistor coupled to the first transistor via a first node; a third transistor coupled to the second transistor via a second node; a fourth transistor coupled to the third transistor via a third node; a capacitive element having a first terminal coupled to the first node and a second terminal coupled to the third node; an inductive element having a first terminal coupled to the second node; and a switch having a first terminal coupled to the first terminal of the inductive element, the switch having a second terminal coupled to a second terminal of the inductive element.

Abstract: Disclosed are methods for performing capillary electrophoresis on two or more nucleic acid samples. The methods employ a forward voltage to move a first sample forward from an inlet to an interrogation region in the capillary, then a backward voltage to move the first sample backward, and then a forward voltage again to move the first sample and a second sample forward. Systems and apparatuses for performing capillary electrophoresis are also provided.

Abstract: A hitch that connects to a chassis of the work vehicle and rotates with respect to the chassis includes a first bracket connected to a first portion of the chassis, a first stabilizer bar connected to the first bracket, and a first hitch arm connected to the first stabilizer bar. The first hitch arm has a free end that engages a work implement. A second bracket is connected to a second portion of the chassis. The second portion of the chassis is spaced from the first portion of the chassis, so that the second bracket is spaced apart from and independent of the first bracket. A second stabilizer bar is connected to the second bracket. A second hitch arm is connected to the first stabilizer bar. The second hitch has a free end configured to selectively engage the work implement.

Abstract: A method for facilitating a multiparty conversation is disclosed. An electronic device using the method may facilitate a multiparty conversation by identifying participants of a conversation, localizing relative positions of the participants, detecting speeches of the conversation, matching one of the participants to each of the detected speeches according to the relative positions of the participants, counting participations of the matched participant in the conversation, identifying a passive subject from all the participants according to the participations of all the participants in the conversation, finding a topic of the conversation between the participants, and engaging the passive subject by addressing the passive subject and speaking a sentence related to the topic.

Abstract: A computer-implemented schema-independent method of modeling data from diverse sources is described. A server transmits to a client computer a blueprint for visualizing and interacting with data, wherein the blueprint defines an application, for visualizing and interacting with data. The application may operate on the client computer within a web browser and may include program code or scripts that operate within the web browser and transmit data and commands to and from the server. In response to receiving a data fetch message from the application, the server receives data from a selected one of a plurality of domains. The server then transforms the received data into a semantic data format. The transformed data is then stored by the server as a first data set. The first data set can then be transmitted to the client computer for further processing and visualization by the application using the blueprint.

Abstract: A mattress 10 is disclosed. The mattress 10 comprises at least two laminated layers 12, 14. The at least two layers 12, 14 include a first layer 12 defining a support surface 16 configured to support a user, and a second layer 14. The first layer 12 is formed from a resiliently deformable, fluid-impervious material, and defines a plurality of perforations 18 arranged to communicate fluid through the layer 12. The second layer 14 is joined to the first layer 12 to cover an end of at least some of the perforations 18, and is formed from a fluid-pervious material. The second layer 14 is arranged to allow fluid to be communicated between at least some of the perforations 18 and a location external to the second layer 14.

Abstract: Systems and methods are provided for initiation, use, access, and control of functionality of a network. In one aspect, the systems and methods can be utilized to generate information defining signaling or control performance and operational characteristics associated with the functionality in a variety of network environments. In another aspect, based on such information, adaptive signaling can be utilized to monitor, analyze and detect specific signaling signatures associated with the functionality. Managing signaling or control messages in response to information collected by monitoring and analyzing the adaptive signaling permits originating or requesting the functionality without conventional operation of a network component.

Abstract: Provided are antibodies and antigen-binding fragments thereof that specifically bind to human neuropilin-2 (NRP2) polypeptides, including those that modulate binding interactions between human NRP2 and at least one NRP2 ligand, for example, human histidyl-tRNA synthetase (HRS), and which thereby modulate subsequent NRP2-mediated downstream signaling events, including related therapeutic compositions and methods for modulating NRP2 activity and treating diseases such as NRP2-associated diseases.