Abstract: A process for producing a photochromic eyewear lens. In one embodiment at least a layer of modified photochromic poly(urea-urethane) is formed by combining photochromic material and the reaction product of a polyurethane pre-polymer and a mixture of diethyltoluene diamine and one or more polyols, plus catalyst. The mixture comprises both NH2 and OH reactive groups, with at least 0.04 equivalent weights of OH reactive species available for reaction with each 1.0 equivalent weight of excess NCO reactive species available in the pre-polymer. The lens comprising the modified photochromic poly(urea-urethane) can exhibit faster fade-back rates and better photochromic performance than lenses with non-modified poly(urea-urethane).

Abstract: The present invention relates to a method of capturing and stabilising volatile thiol malodour generated on the human skin, comprising steps of: i) contacting the human skin with a substrate, ii) absorbing said thiol into the substrate, and iii) reacting said thiol with a thiol-capture agent. The invention also relates to a method of quantifying said thiol, a method of assessing the deodorizing performance of a cosmetic composition on the human skin.

Abstract: A system and method for installing replacement plungers in plunger pumps used in the hydrocarbon industry. The system includes an elongated, cylindrical plunger body with an elongated circular tube disposed around the cylindrical plunger body. An end wall having an aperture formed therein encloses one end of the tube with an axially movable plate disposed within the tube adjacent the end wall between the end wall and the first plunger end of the plunger body. A removable cap is mounted to the opposite end of the tube to enclose and secure the plunger body within the tube. The outer diameter of the tube is sized to fit in the plunger bore of a pump. To install the replacement plunger, the cap is removed from the end of the tube and the tube is inserted into the plunger bore until the tube abuts packing within the tube. Once positioned, an axial force is applied to the movable plate in order to urge the plunger body from the tube and into engagement with the packing.

Abstract: Indazole compounds for treating various diseases and pathologies are provided. More particularly, the use of an indazole compound or analogs thereof, in the treatment of inflammatory diseases or disorders is provided.

Abstract: Systems and methods for managing transactions of physical objects are disclosed. The system is connectable to a first distributed ledger adapted to record object transactions associated with transactions of one or more physical objects between parties. The system includes a second distributed ledger adapted to record data indicative of object handling operations carried out with respect to the one or more physical objects; and an object handling management module adapted to authenticate handling operations carried out with respect to the one or more physical objects. The object handling management module is configured and operable for obtaining parameters of execution of the handling operations, authenticating the parameters of execution of the handling operations, and recording the authenticated handling operations in the second distributed ledger.

Abstract: A method for mapping sweat production from the human skin, said method comprising the application of a polydiacetylene (PDA) prepared from a derivative of a conjugated diynoic acid having at least 18 carbon atoms, wherein the PDA changes colour when exposed to sweat, but does not change colour when exposed to pure water.

Abstract: This application provides a computer-implemented method for providing notifications. The method includes a) creating a geofenced area associated with a mobile device and a healthcare facility, wherein the patient is associated with the mobile device, b) storing the geofenced area in a data store, c) determining when the mobile device has crossed or entered the geofenced area during an unscheduled visit to the healthcare facility by the patient, d) sending a notification to or retrieving the notification from the mobile device, wherein the notification includes the medical history of the patient, the type of healthcare facility associated with the geofenced area, the insurance network of the patient, the medical providers practicing at the healthcare facility, wait times at the healthcare facility, and the proximity to other healthcare facilities, and e) outputting the notification to the mobile device when mobile device is within the geofenced area.

Abstract: A vehicle includes a pump having a swash plate tiltable about a swashplate tilt axis, wherein rotation of the swashplate changes the title angle and effects a change in volumetric displacement of the pump. A controller is operatively coupled to the swashplate to effect rotation of the swashplate, the controller including a processor and memory, and logic stored in the memory and executable by the processor, the logic configured to automatically control at least one vehicle characteristic independent of a user input command.

Abstract: Provided are compositions and methods for treating osteoarthritis including intra-articular administration of a compound of Formula (I) including amorphous and polymorph forms thereof.

Abstract: According to some embodiments, a method performed by a first software defined wide area network (SD-WAN) edge router communicably coupled to a public network comprises: receiving a transport location (TLOC)-extension configuration for a known interface of the first edge router; detecting a second edge router attempting to connect to the known interface of the first edge router; and transmitting, to the second edge router, configuration information for the second edge router so that the second edge router is able to communicate with the public network through a TLOC-extension with the first edge router. In some embodiments, the second edge router receives device configuration information (e.g., PnP, ZTP, etc.) from the public network via the TLOC-extension.

Abstract: A method for operating a magnetic resonance imaging (MRI) system that includes: accessing data indicating a first region for imaging a portion of a subject, the portion being placed in a main magnet of the MRI system and the main magnet generating a magnetic field; selecting, from a group of available shimming coils, a first subset of shimming coils arranged and configured such that, when the shimming coils in the first subset are driven, a homogeneity of the magnetic field at the first region is increased; and driving the shimming coils in the selected first subset of shimming coils without driving other shimming coils in the group of available shimming coils such that the homogeneity of the magnetic field at the first region increases relative to the homogeneity of the magnetic field at the first region when the shimming coils of the selected first subset are not driven.

Abstract: A pump fluid end comprising: a reciprocating element disposed at least partially within a reciprocating element bore of the pump fluid end; a discharge valve assembly; a suction valve assembly coupled with a front end of the reciprocating element; and a suction valve stop, wherein the suction valve stop is positioned within the reciprocating element bore such that the suction valve stop contacts and applies a closing force to the suction valve assembly when the suction valve assembly is stuck open at the end of a discharge stroke of the reciprocating element.

Abstract: A pump fluid end comprising: a reciprocating element disposed within a reciprocating element bore and having an outer surface; a reciprocating element packing positioned within the reciprocating element bore; and optionally a sleeve positioned within the reciprocating element bore and having an inner surface proximate the outer surface of the reciprocating element, wherein at least a portion of the outer surface of the reciprocating element and/or the inner surface of the sleeve is coated with a multi-layer surface coating comprising a plurality of layers including: a first layer in contact with the at least a portion of the outer surface of the reciprocating element and/or the inner surface of the sleeve; and a second layer disposed over at least a portion of the first layer; and wherein at least one of the plurality of layers has a different visual appearance and/or material composition than another of the plurality of layers.

Abstract: A pump fluid end includes a body that defines a plunger bore and a working fluid bore that intersects the plunger bore to form a cross bore. A packing bore is defined in the plunger bore and includes a packing sleeve bore, a taper relief bore, and a transition bore. The packing sleeve bore transitions to the taper relief bore at a radial shoulder and the taper relief bore transitions to the plunger bore across the transition bore. The transition bore extends between an external corner contiguous with the plunger bore and an internal corner contiguous with the taper relief bore and at least one of the external and internal corners is rounded and exhibits a radius. The packing bore is treated with a surface pre-stressing treatment.

Abstract: A modular porting manifold for a hydrostatic transmission that serves as an end cover for the hydraulic motor, and which may be modularly interfaced with multiple different pump configurations having the same or similar pump interface across the different pump configurations. A pump interfacing section of the porting manifold may have a mating surface that interfaces with a corresponding mating surface of an outwardly addressable manifold of the pump. The pump interfacing section of the porting manifold may have at least two ports for communication of hydraulic fluid with the pump, in which the at least two ports are laterally spaced apart in the same horizontal plane to align with at least two corresponding ports on the pump manifold that are also in the same horizontal plane, which may provide less complex and easier to manufacture flow passages for the porting manifold and/or pump end block.

Abstract: Cleaning systems and devices are provided for cleaning body-inserted tubes (e.g., endotracheal tubes, chest cleaning tubes). In one embodiment, a closed suction system includes a suction catheter having at least one deployable (e.g., inflatable) cleaning member at a distal portion of the suction catheter and at least one suction opening distal to the cleaning member. The closed suction system module may include a control unit at its proximal end adapted to facilitate operation in one of the following three operational states: i) a first operational state in which only the cleaning member is functional, ii) a second operational state in which only suction is functional, or iii) a third operational state in which neither suction nor the cleaning member is functional.

Abstract: This document relates to methods and materials for generating oilseed (e.g., pennycress) plants that have oil with reduced levels of polyunsaturated fatty acids (PUFAs) and/or increased levels of oleic acid. For example, oilseed plants having reduced expression levels of one or more polypeptides involved in fatty acid biosynthesis (e.g., fatty acid desaturase 2 (FAD2) and reduced oleate desaturation 1 (ROD1)), as well as methods and materials for making and using such oilseed plants are provided.

Abstract: A walking aid in the form of a walking stick 10 with a handle part 12 and a foldable support part 14. A rechargeable battery is provided in the handle part 12 to selectively illuminate a lighting element in the form of a plurality of LED's 28 in a lowermost section 16A of the support part 14.

Abstract: A hose for a reciprocating pump, the hose comprising: a first end and a second end separated by a length (L) along a centerline of the hose, wherein the first end reciprocates with a reciprocating element of the reciprocating pump during operation of the reciprocating pump; an inner surface and an outer surface separated by a thickness; and a variable bend radius wherein a bend radius of a first section of the hose is different from a bend radius of at least one second section of the hose, such that, during operation of the reciprocating pump, a stress on the first end of the hose, the second end of the hose, or both the first end of the hose and the second end of the hose is reduced relative to that of a hose that does not contain the variable bend radius.

Abstract: A photochromic multilayer laminate with excellent darkening and fade-back speed and an eyewear lens incorporating the laminate are described. The laminate comprises at least three layers of polyvinyl alcohol, in which the third layer, comprising polyvinyl alcohol and one or more photochromic materials, is positioned between the surfaces of the two other polyvinyl alcohol layers. In one embodiment, the laminate is free of polarizer components and polarizing coatings. In other embodiments, the photochromic materials in the third layer have a form selected from the group including nanodroplets, photochromic nanoparticles and encapsulated forms with a capsule size between about 20 and 500 nm. The laminate and the eyewear lens may have additional layers, elements and additives.