Abstract: A composite drug delivery material may be injected into an eye of a human being or mammal to provide sustained delivery of the drug. A composite drug delivery material may include a plurality of microparticles dispersed in a media composition. The microparticles may contain a drug and a coating comprising a bioerodible material or a biodegradable material, and the media composition includes the drug dispersed in a depot-forming material. The media composition may gel or solidify upon injection into the eye.

Abstract: A composite drug delivery material may be injected into an eye of a human being or mammal to provide sustained delivery of the drug. A composite drug delivery material may include a plurality of microparticles dispersed in a media composition. The microparticles may contain a drug and a coating comprising a bioerodible material or a biodegradable material, and the media composition includes the drug dispersed in a depot-forming material. The media composition may gel or solidify upon injection into the eye.

Abstract: A composite drug delivery material may be injected into an eye of a human being or mammal to provide sustained delivery of the drug. A composite drug delivery material may include a plurality of microparticles dispersed in a media composition. The microparticles may contain a drug and a coating comprising a bioerodible material or a biodegradable material, and the media composition includes the drug dispersed in a depot-forming material. The media composition may gel or solidify upon injection into the eye.

Abstract: A composite drug delivery material may be injected into an eye of a human being or mammal to provide sustained delivery of the drug. A composite drug delivery material may include a plurality of microparticles dispersed in a media composition. The microparticles may contain a drug and a coating comprising a bioerodible material or a biodegradable material, and the media composition includes the drug dispersed in a depot-forming material. The media composition may gel or solidify upon injection into the eye.

Abstract: Disclosed herein are autoclavable formulations of cyclosporin A Form 2, methods of making such formulations, and methods of treating diseases of the eye with such formulations.

Abstract: Disclosed herein are autoclavable formulations of cyclosporin A Form 2, methods of making such formulations, and methods of treating diseases of the eye with such formulations.

Abstract: Disclosed herein are autoclavable formulations of cyclosporin A Form 2, methods of making such formulations, and methods of treating diseases of the eye with such formulations.

Abstract: Disclosed herein are autoclavable formulations of cyclosporin A Form 2, methods of making such formulations, and methods of treating diseases of the eye with such formulations.

Abstract: The present invention is directed to an ophthalmic peri-corneal drug delivery device. The device includes a core of matrix material and therapeutic agent and a coating over the core. One or more opening[s] extend through the coating to provide for release of the drug to the eye. Moreover, the device is designed to lay atop the external surface of the eye.

Abstract: A method of treating contact lenses comprising the use of an iodine-chromophore to indicate neutralization of oxidative disinfectants.

Abstract: A composition and method for cleaning and disinfecting of contact lenses that employ an electrical field applied to a lens that causes contaminating deposits to migrate therefrom is described. The composition of the invention includes a pair of component materials having different electrochemical potentials wherein the materials are substantially contained in a form wherein each material remains sufficiently physically separated when in contact with opposite sides of the lens such that the difference in electrochemical potential between the two materials is sufficient to cause charged contaminating deposits to migrate from the lens. The method of the invention requires placing a contaminated lens between a pair of component materials having different electrochemical potentials wherein physical separation is maintained, preferably, by including one of the components in a gel while the other component is in solution or another gel.

Abstract: Contact lenses are cleaned by contacting the lenses with a composition containing an effective amount of one or more cyclodextrins. The compositions can also be employed at elevated temperatures or may contain suitable antimicrobial agents in order to simultaneously clean and disinfect the lenses.

Abstract: This invention relates to ester derivatives of 4-hydroxy-4-androstene-3,17-dione (4-OH-4-A), including the acetate, heptanoate, dodecanoate, hemisuccinate and benzoate esters of 4-OH-4-A.This invention also relates to a method of using the esters in the inhibition of estrogen biosynthesis.