Abstract: This disclosure describes techniques for identifying an application (e.g., accessing application) that is attempting to access a resource. In some examples, access may be managed by an authentication service. When an access request is received at the authentication service from an application on a client device, the authentication service may ask the application to communicate with an identification agent on the client device. The identification agent may perform one or more tests to discover the identity of the application. In some cases, the identification agent may send the identity of the application to the authentication service. The authentication service may then allow or deny access by the accessing application to the resource based at least in part on the discovered identity.

Abstract: An antibacterial polypeptide and methods of use are described.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue to cause altered activity at a synapse between a neuron and a non-neuronal cell.

Abstract: This disclosure describes techniques for identifying an application (e.g., accessing application) that is attempting to access a resource. In some examples, access may be managed by an authentication service. When an access request is received at the authentication service from an application on a client device, the authentication service may ask the application to communicate with an identification agent on the client device. The identification agent may perform one or more tests to discover the identity of the application. In some cases, the identification agent may send the identity of the application to the authentication service. The authentication service may then allow or deny access by the accessing application to the resource based at least in part on the discovered identity.

Abstract: A high-frequency dynamic pressure transducer calibration system and method is provided. The method directs a source onto a diaphragm of a dynamic pressure transducer. An oscillating voltage at a target frequency (or range of frequencies) is generated. The oscillating voltage is coupled to an electrical connector of the dynamic pressure transducer. A deflection pattern of the diaphragm is recorded. The dynamic pressure transducer is calibrated by correlating magnitude of the deflection pattern with the oscillating voltage as a function of the target frequency (or range of frequencies).

Abstract: Methods and compositions for use of human milk oligosaccharides for prevention and treatment of airway viral infections are provided.

Abstract: Provided herein are deglycosylating enzymes that remove a broad range of N-glycans from N-glycosylated proteins. Further provided are methods of recombinantly producing and expressing the deglycosylating enzymes. The presently described deglycosylating enzymes can be used to produce free glycans for characterization, and for prebiotic and immunostimulatory uses. In addition, the presently described deglycosylating enzymes can be used to produce deglycosylated proteins for characterization, to improve digestion, and to reduce immunogenicity.

Abstract: A packer for anchoring and sealing to a tubular in a well, the packer including a packer element, an anchoring arrangement, a setting mechanism and a release mechanism. The release mechanism holds a thin-walled section of tubing in the packer in tension using a biasing mechanism. On severing the tubing, the bias releases an engagement mechanism which allows the anchor arrangement and the packing element to move relative to the body and thereby unset the packer. An embodiment of a dual bore packer is described. A method of well isolation is described, with an assembly including the dual bore packer. The primary bore forms the short string and a secondary bore forms the long string. By severing the short string the integrity of the long string is maintained to pull lower devices on the long string and the short string does not require tension below the packer to release.

Abstract: An antibody or antigen binding fragment thereof that binds to a Fn14, wherein the antibody or antigen binding fragment thereof is an antagonist and non-agonist of Fn14.

Abstract: This disclosure describes techniques for identifying an application (e.g., accessing application) that is attempting to access a resource. In some examples, access may be managed by an authentication service. When an access request is received at the authentication service from an application on a client device, the authentication service may ask the application to communicate with an identification agent on the client device. The identification agent may perform one or more tests to discover the identity of the application. In some cases, the identification agent may send the identity of the application to the authentication service. The authentication service may then allow or deny access by the accessing application to the resource based at least in part on the discovered identity.

Abstract: The combination of specific immunoglobulins plus activated Bifidobacteria strains or other beneficial bacteria is described with the designed efficacy to colonize unstable microbiome communities in humans or other animals, restoring the keystone Bifidobacteria strains or other beneficial bacteria to compositional and functional importance in the intestine and improve overall health and reduce pathogenic infections in the host. Secretory immunoglobulin A (SIgA), when bound via specific glycans to select commensal bacteria grown on human milk oligosaccharides (HMOs), enhances the colonization potential of commensals through protection from intestinal digestion, enhancing attachment, and dampening host immune response.

Abstract: A storage system comprising: a pair of rails, comprising a first rail and a second rail; rail mounts for mounting the first and second rails in an at least generally parallel orientation in position on or to a supporting surface; a storage frame defining a storage space for storing items therein; a first connector for connecting the storage frame to the first rail; and a second connector for connecting the storage frame to the second rail; wherein the first connector includes a first connector rail part and a first connector frame part, with the first connector rail part provided on the first rail; and the first connector frame part provided on the storage frame, with one of the first connector rail part and the first connector frame part slidably receivable in the other of the first connector rail part and the first connector frame part.

Abstract: A storage system, comprising: a frame, the frame comprising two opposing frame side walls, a frame rear wall, a frame top wall and a frame base, which collectively define a drawer receiving space; the frame having a front opening; a drawer receivable in the drawer receiving space through the front opening; the drawer comprising first and second opposing drawer side walls, a drawer base, a drawer front wall and a drawer rear wall, which collectively define a drawer storage space, the drawer having a top opening for receiving contents into the drawer storage space; a drawer position retainer for releasably retaining the drawer in any one of at least two drawer positions relative to the frame, the at least two drawer positions comprising: a closed position, wherein the drawer is at least substantially received within the frame; and a partially open position, wherein the drawer is partially received within the frame; and an actuator mounted to or adjacent the drawer front wall for manually actuating the drawer po

Abstract: Synthetic oligosaccharides and mixtures thereof which resemble polysaccharides produced by plants, yeast and other fungi, bacteria, and algae are described. The oligosaccharides and compositions provided herein are useful as synbiotics, prebiotics, immune modulators, digestion aids, and food additives.

Abstract: A packer for anchoring and sealing to a tubular in a well, the packer including a packer element, an anchoring arrangement, a setting mechanism and a release mechanism. The release mechanism holds a thin-walled section of tubing in the packer in tension using a biasing mechanism. On severing the tubing, the bias releases an engagement mechanism which allows the anchor arrangement and the packing element to move relative to the body and thereby unset the packer. An embodiment of a dual bore packer is described. A method of well isolation is described, with an assembly including the dual bore packer. The primary bore forms the short string and a secondary bore forms the long string. By severing the short string the integrity of the long string is maintained to pull lower devices on the long string and the short string does not require tension below the packer to release.

Abstract: The present invention relates to the use of contrast-enhanced ultrasound using microbubble-based ultrasound contrast agents to accomplish noninvasive subharmonic aided pressure estimation (SHAPE) in a region of interest (ROI) of a subject. The method of the invention provides a non-invasive, direct, and accurate method for pressure estimation.

Abstract: A cleaning system and method use an ultrasound probe, a coupling mechanism, and a controller to clean equipment of a vehicle system. The ultrasound probe enters into an engine. The ultrasound probe emits ultrasound pulses and the coupling mechanism provides an ultrasound coupling medium between the ultrasound probe and one or more components of the engine. The controller drives the ultrasound probe to deliver the ultrasound pulse through the coupling medium to a surface of the one or more components of the engine. The ultrasound probe delivers the ultrasound pulse to remove deposits from the one or more components of the engine.

Abstract: Methods of reducing milk glycans, and thus enteric pathogens that use such glycans as carbon sources, in the gut of nursing mammals.

Abstract: Embodiments of the invention disclosed herein include devices for sterilizing items, particularly hand-held writing implements, using ultraviolet radiation. Other useful features of the sterilizer embodiments include a no touch proximity sensor for opening the lid to access sterilization ports and any items within the ports, automatic descent of the items into the sterilizer and closure of the lid for a preselected sterilization cycle without the lid binding on the items in the ports.