Abstract: A steel strip having a hot dip zinc based coating, the steel strip having the following composition, in weight %: C: 0.17-0.24 Mn: 1.8-2.5 Si: 0.65-1.25 Al: ?0.3 optionally: Nb: ?0.1 and/or V: ?0.3 and/or Ti: ?0.15 and/or Cr: ?0.5 and/or Mo: ?0.3, the remainder being iron and unavoidable impurities; with a Si/Mn ratio ?0.5 and a Si/C ratio ?3.0, with an Mn equivalent ME of at most 3.5, wherein ME=Mn+Cr+2 Mo (in wt. %); having a microstructure with (in vol. %): ferrite: 0-40, bainite: 20-70, martensite: 7-30, retained austenite: 5-20, pearlite: ?2, cementite: ?1; having a tensile strength in the range of 960-1100 MPa, a yield strength of at least 500 MPa, and a uniform elongation of at least 12%.

Abstract: A radiation curable composition is disclosed that includes a curable cross-linker essentially free of urethane and urea functional groups, a curable diluent, and a non-radiation curable component comprising (thio)urethane and/or urea groups. Coated optical fibers having a primary coating formed from this radiation curable composition, as well as optical fiber ribbons that contain the coated optical fibers are disclosed. Methods of making the optical fibers and ribbons are also disclosed.

Abstract: A high strength hot dip galvanized steel strip including, in mass percent, of the following elements: 0.10-0.18% C, 1.90-2.50% Mn, 0.30-0.50% Si, 0.50-0.70% Al, 0.10-0.50% Cr, 0.001-0.10% P, 0.01-0.05% Nb, max 0.004% Ca, max 0.05% S, max 0.007% N, and optionally at least one of the following elements: 0.005-0.50% Ti, 0.005-0.50% V, 0.005-0.50% Mo, 0.005-0.50% Ni, 0.005-0.50% Cu, max 0.005% B, the balance Fe and inevitable impurities, wherein 0.80%<Al+Si<1.05% and Mn+Cr>2.10%. This steel offers improved formability at a high strength, has a good weldability and surface quality together with a good produce-ability and coat-ability.

Abstract: The present disclosure provides expression vectors containing a nucleic acid encoding an RNA polymerase III promoter, a ribozyme, a CRISPR-Cas9 single guide RNA, and an RNA polymerase III terminator, where the ribozyme is 5? to the CRISPR-Cas9 single guide RNA, as well as ribonucleic acids encoded thereby. Further provided are fungal cells containing an expression vector described herein, as well as methods of fungal genome engineering through use of an expression vector described herein.

Abstract: An improved process for synthesizing acrylic polymers, which is highly controllable to achieve high molecular weight, high conversion rate, and low polydispersity involves continuously introducing initiator(s), acrylic monomer(s), and optionally other monomers capable of polymerizing with the acrylic monomer(s), into a microchannel of a microreactor having an integral micromixer and an integral heat exchanger.

Abstract: A coating composition including a reinforcing agent. The coating composition may include one or more radiation-curable monofunctional monomers, one or more radiation-curable multifunctional monomers or oligomers, a photoinitiator, and a reinforcing agent. The monofunctional monomers, multifunctional monomers, and multifunctional oligomers may include acrylate groups. The reinforcing agent may be an acrylic co-polymer that includes two or more repeat units. At least one of the repeat units includes chemical groups that enable self-association of the acrylic co-polymer. Self-association of the acrylic co-polymer may improve the tensile strength of coatings formed from the coating compositions.

Abstract: A method of synthesizing urethane-free polyfunctional acrylate compounds. The method includes reaction of a polyol with acrylic acid in the presence of an inhibitor. A catalyst may also be present. The catalyst may be an acid and the inhibitor may be a substituted phenol compound. Excess acid may be removed by adding a salt and excess water may be removed by adding a drying agent. The reaction converts alcohol groups of the polyol to acrylate groups to provide a radiation-curable polyfunctional acrylate compound. The reaction is applicable to polyols generally and provides a scalable high yield process for forming urethane-free polyfunctional acrylates over a wide range of molecular weights. Coatings made from the acrylate products exhibit modulus and tensile strength characteristics favorable for primary fiber coatings.

Abstract: An optical fiber is disclosed that includes a primary coating formed from a radiation curable composition that includes a curable cross-linker essentially free of urethane and urea functional groups, a curable diluent, and a non-radiation curable component comprising (thio)urethane and/or (thio)urea groups. The primary coating features low Young's modulus, low Tg, and high tensile strength. The optical fiber exhibits low microbend losses in wire mesh drum and basketweave tests.

Abstract: A steel for hot forming. The steel for hot forming has the following composition in weight%: C: 0.10-0.25, Mn: 1.4-2.6, Si:<0.4, Cr:<1.0, Al:<1.5, P:<0.02, S:<0.005, N:<0.03, B:<0.0004, 0:<0.008 and optionally: Ti:<0.3, Mo:<0.5, Nb:<0.3, V:<0.5, Ca:<0.05, the remainder being iron and unavoidable impurities.

Abstract: Articles utilizing polymeric dielectric materials for gate dielectrics and insulator materials are provided along with methods for making the articles. The articles are useful in electronics-based devices that utilize organic thin film transistors.

Abstract: A non-radiation curable reinforcing agent for optical fiber coatings and coating compositions. The reinforcing agent includes structurally flexible soft block segments and structurally rigid hard block segments. The soft block segments and hard block segments include urethane or urea linkages and act as strengthening additives in optical fiber coatings. Strength reinforcement occurs through interactions of the reinforcing agent with the polymeric network formed from curable components of the coating composition. Interactions include physical entanglements and hydrogen bonding. Soft block segments include block units that may include high molecular weight polyol linkages and soft block segments include block units that may include low molecular weight alkylene linkages. Coatings that include the reinforcing agents exhibit low Young's modulus, high tensile strength, and low glass transition temperatures and are suitable for use as primary coatings in optical fibers.

Abstract: An optical fiber coating composition is provided. The optical fiber coating composition includes a radiation-curable component, a photoinitiator, and an acrylic polymer having at least one benzophenone group.

Abstract: Coating compositions that include acrylic polymers as reinforcing agents. The coating compositions are radiation-curable and include a multifunctional acrylate component, an acrylic monomer diluent, an acrylic polymer, and a photoinitiator. The acrylic polymer is not radiation-curable and lacks hydrogen-donor groups, urea groups, and urethane groups. The acrylic polymer is non-reactive and does not chemically bond to the crosslinked network formed by curing the acrylate components. Instead, the acrylic polymer reinforces the cured network through physical interactions. Representative acrylic polymers include (meth)acrylates that lack substituents with hydrogen-donor, urea, and urethane groups.

Abstract: This disclosure relates to novel xylose isomerases and their uses, particularly in fermentation processes that employ xylose-containing media.

Abstract: The present invention relates to the use of VPS28 and/or VPS13A as biomarkers for diagnosing prostate cancer, prostate intraepithelial neoplasia (PIN) or atypical small acinar proliferation (ASAP) and to the use of VPS13A, VPS28 and/or NAALADL2 as biomarkers for predicting the prognosis of prostate cancer. The invention also relates to the use of VPS13A, VPS28 and/or NAALADL2 as biomarkers for determining the grade or pathological stage of prostate cancer and monitoring progression of prostate cancer. In addition, the invention relates to the use of NAALADL2 as a biomarker for diagnosing colon, pancreatic or breast cancer. Assays, systems and storage media based on the use of these biomarkers are also provided.

Abstract: An improved process for synthesizing acrylic polymers, which is highly controllable to achieve high molecular weight, high conversion rate, and low polydispersity involves continuously introducing initiator(s), acrylic monomer(s), and optionally other monomers capable of polymerizing with the acrylic monomer(s), into a microchannel of a microreactor having an integral micromixer and an integral heat exchanger.

Abstract: An optical fiber coating composition that includes an acrylic copolymer. The acrylic copolymer is a block copolymer that includes two or more acrylic blocks. The two or more acrylic blocks differ in glass transition temperature (Tg). The acrylic copolymer may include an acrylic block with a Tg above 50° C. and an acrylic block with a Tg below 0° C. Representative monomers from which the repeat units of the acrylic blocks are derived include alkyl(meth)acrylates. In one embodiment, the acrylic copolymer includes an acrylic block with repeat units derived from methylmethacrylate and an acrylic block derived from butylacrylate. The acrylic copolymer lacks urethane groups, lacks urea groups, lacks radiation-curable groups, and is otherwise unreactive with other components in the coating composition. The acrylic copolymer features high solubility in common acrylate-based radiation-curable coating compositions and can be provided at high concentrations in acrylate-based coating compositions.

Abstract: Aircraft and airframes include a skin operatively coupled to a structural reinforcement member. The structural reinforcement member and the skin collectively define a run-out region that encompasses a terminal edge of the structural reinforcement member. Within the run-out region, the skin is more flexible than in adjacent portions of the skin. Methods include defining a region of increased flexibility of a skin relative to adjacent portions of the skin, and operatively coupling the skin to a structural reinforcement member.

Abstract: An optical fiber is disclosed that includes a primary coating formed from a radiation curable composition that includes a curable cross-linker essentially free of urethane and urea functional groups, a curable diluent, and a non-radiation curable component comprising (thio)urethane and/or (thio)urea groups. The primary coating features low Young's modulus, low Tg, and high tensile strength. The optical fiber exhibits low microbend losses in wire mesh drum and basketweave tests.

Abstract: A low cost composition that cures rapidly and which is suitable for coating an optical fiber comprises at least one ethylenically unsaturated monomer; at least one photoinitiator; and at least one non-radiation-curable polar polymer having pendent groups that facilitate low energy chemical bonding, hydrogen bonding, dipolar interactions or other interactions with radical compounds formed during polymerization of the monomer. The non-radiation-curable polar polymer(s) are inexpensive and reduce and/or eliminate the need for expensive urethane acrylate oligomers, without sacrificing properties, and while achieving rapid cure speeds.