Abstract: A method for generating device specific thumbnails may includes receiving one or more databases on a computing device from a mobile electronic device where the one or more databases include a key file and a data file. The data file may include picture data and the key file may include an index to the picture data. Also, the method may include generating a synchronization set on the computing device wherein the synchronization set includes one or more picture files to be stored on the mobile electronic device. The one or more databases may be transformed to one or more updated databases, wherein the transforming includes updating the key file to index pictures included in the synchronization set and updating the data file to include thumbnails of the pictures included in the synchronization set. The one or more updated databases may be transmitted to the mobile electronic device.

Abstract: A data storage device (DSD) including a first non-volatile memory (NVM) media type for storing data and a second NVM media type for storing data. Metadata is obtained related to operation of the second NVM media type. The metadata is evaluated and data stored in the first NVM media type is managed based on the evaluated metadata.

Abstract: A splined muff is provided for use with a ram air turbine (RAT). The splined muff includes a body formed of plastic material that acts as an insulator during a lightning strike. The body is formed to define an aperture and includes an interior facing spline for engagement with a complementary exterior facing spline; and an exterior facing spline for engagement with a complementary interior facing spline.

Abstract: In at least one embodiment, a method of analyzing and characterizing the thermal growth of a CNC machine is provided. The method may include mounting an artifact having a bore onto a CNC machine and performing a test cycle. The test cycle may include probing the bore of the artifact to determine its location relative to the CNC machine and performing a dry cycle including one or more CNC machining processes. The method may further include calculating a deviation of the bore location from a reference relative location between the bore and CNC machine. The method may be used to improve, troubleshoot, or assess the effectiveness of CNC machine thermal compensation mechanisms. The method may start at ambient temperature and include repeating test cycles until a steady state temperature is reached in the machine.

Abstract: A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.

Abstract: What is defined is a stow lock pin for use in preventing deployment of a ram air turbine of an aircraft, the aircraft having a first distance from the ram air turbine to an access window. The stow lock pin includes a tip configured to be received by a slot of the ram air turbine. The stow lock pin also includes a rod coupled to the tip and having an axial distance that is larger than the first distance.

Abstract: Compounds of Formula I and methods of treating diseases of metabolism by modulating cellular NAD+ levels through the inhibition of the CD38 enzyme, are disclosed.

Abstract: Haematopoietic stem cell mobilization is a process whereby haematopoietic stem cells are stimulated out of the bone marrow space. Before HSC can mobilize, they must be dislodged and released from the BM stem cell niche in which they reside and are retained by adhesive interactions. Accordingly, in an aspect of the present invention there is provided a method for enhancing dislodgement of HSC and their precursors and progenitors thereof from a BM stem cell binding ligand in vivo or ex vivo, said method comprising administering in vivo or ex vivo an effective amount of an antagonist of an a 9 integrin or an active portion thereof to the BM stem cell niche. Once mobilized to the peripheral blood (PB) the HSC may be collected for transplant. Methods which enhance mobilization of the HSC can also improve treatments of haematological disorders.

Abstract: Haematopoietic stem cell mobilization is a process whereby haematopoietic stem cells are stimulated out of the bone marrow space. Before HSC can mobilize, they must be dislodged and released from the BM stem cell niche in which they reside and are retained by adhesive interactions. Accordingly, in an aspect of the present invention there is provided a method for enhancing dislodgement of HSC and their precursors and progenitors thereof from a BM stem cell binding ligand in vivo or ex vivo, said method comprising administering in vivo or ex vivo an effective amount of an antagonist of an ?9 integrin or an active portion thereof and a CXCR4 antagonist or an active portion thereof to the BM stem cell niche. Once mobilized to the peripheral blood (PB) the HSC may be collected for transplant. Methods which enhance mobilization of the HSC can also improve treatments of haematological disorders.

Abstract: A method includes placing a treatment fluid including a crosslinked gel in a wellbore penetrating a subterranean formation, the crosslinked gel including a gelling agent and a borate crosslinking agent, de-crosslinking a portion of the crosslinked gel, the de-crosslinking induced by a sufficient change in operating pressure, the de-crosslinking providing a release of active sites on the borate crosslinking agent and reducing the viscosity of the treatment fluid, and providing a borate-affinity agent to capture the released active sites on the borate crosslinking agent. A fracturing fluid includes a gelling agent, a borate crosslinking agent, a latent borate-affinity agent, and a proppant.

Abstract: A marine vessel comprising: at least one buoyant tubular foil; and at least one baffle plate positioned about the perimeter of the at least one buoyant tubular foil so as to protrude into the flow of water passing by the perimeter of the at least one buoyant tubular foil, whereby to create a high-pressure zone fore of the at least one baffle plate and a low-pressure zone immediately aft of the at least one baffle plate, whereby to create a dense stream of supercavitated water immediately aft of the at least one baffle plate.

Abstract: Compounds of Formula I and methods of treating diseases of metabolism by modulating cellular NAD+ levels through the inhibition of the CD38 enzyme, are disclosed.

Abstract: Some embodiments disclosed herein are directed to a pump assembly comprising a voice coil, a magnet and a diaphragm, wherein the voice coil is configured to move the diaphragm to pump a fluid through the pump assembly in response to a drive signal applied to the voice coil. Some embodiments disclosed herein are directed to an apparatus for applying negative pressure to a wound comprising a source of negative pressure configured to be coupled to a dressing, the source of negative comprising a voice coil actuator and a diaphragm, and a controller configured to produce a drive signal for the voice coil actuator.

Abstract: Methods and systems for facilitating group payment are disclosed. In one embodiment, a group payment system is configured to execute instructions to perform operations that include receiving, from a first computing device, a request to create a group payment event and, in response, providing to the first computing device a first interface associated with the group payment event. The operations further include receiving, from a second computing device, a request to join the group payment event and, in response, providing a second interface to the second computing device. The operations further include receiving, from the first and/or second computing devices, messages associated with the group payment event and modifying the first and second interfaces to display the messages. The operations further include receiving, from the first and/or second computing devices, financial contributions for the group payment event and modifying the first and second interfaces to display the financial contributions.

Abstract: In one embodiment there is provided an aquatic toy configured for movement under water. The aquatic toy employs sensors to automatically turn on when placed in water and further employs a timing circuit to automatically turn the toy off after a predetermined amount of time. The aquatic toy further includes a shock sensor to monitor movement of the toy when in water and after the timer expires. Movement such as tapping on the tank, splashing the water, or physical movement of the toy will turn on the toy and re-activate the timer. However, the sensors can further detect when the toy is dry to ensure the shock sensor is only active when the sensor is wet.

Abstract: A splined muff is provided for use with a ram air turbine (RAT). The splined muff includes a body formed of plastic material that acts as an insulator during a lightning strike. The body is formed to define an aperture and includes an interior facing spline for engagement with a complementary exterior facing spline; and an exterior facing spline for engagement with a complementary interior facing spline.

Abstract: A marine vessel comprising: at least one buoyant tubular foil; and at least one baffle plate positioned about the perimeter of the at least one buoyant tubular foil so as to protrude into the flow of water passing by the perimeter of the at least one buoyant tubular foil, whereby to create a high-pressure zone fore of the at least one baffle plate and a low-pressure zone immediately aft of the at least one baffle plate, whereby to create a dense stream of supercavitated water immediately aft of the at least one baffle plate.

Abstract: Some embodiments disclosed herein are directed to a pump assembly comprising a voice coil, a magnet and a diaphragm, wherein the voice coil is configured to move the diaphragm to pump a fluid through the pump assembly in response to a drive signal applied to the voice coil. Some embodiments disclosed herein are directed to an apparatus for applying negative pressure to a wound comprising a source of negative pressure configured to be coupled to a dressing, the source of negative comprising a voice coil actuator and a diaphragm, and a controller configured to produce a drive signal for the voice coil actuator.

Abstract: Some embodiments disclosed herein are directed to a pump assembly comprising a voice coil, a magnet and a diaphragm, wherein the voice coil is configured to move the diaphragm to pump a fluid through the pump assembly in response to a drive signal applied to the voice coil. Some embodiments disclosed herein are directed to an apparatus for applying negative pressure to a wound comprising a source of negative pressure configured to be coupled to a dressing, the source of negative comprising a voice coil actuator and a diaphragm, and a controller configured to produce a drive signal for the voice coil actuator.

Abstract: The present invention discloses thioflavine S and primuline derivatives which inhibit hepatitis C virus helicase and protease activity. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are useful as antiviral agents. The present invention further relates to pharmaceutical compositions containing the aforementioned compounds and methods of treating an HCV infection.