Abstract: A catheter body includes an exit port over which a pressure responsive sleeve is formed that allows material to exit a lumen of the catheter body at a given pressure. In one embodiment, a surface of the sleeve is approximately flush with a surface of the catheter body.

Abstract: The present invention provides pressure-sensitive adhesives having a refractive index of at least 1.48. The pressure-sensitive adhesives comprise at least one monomer containing a substituted or an unsubstituted aromatic moiety.

Abstract: Methods and compositions for detecting, typing or characterizing HPV DNA are disclosed. The methods can include isolation of DNA from a patient and amplifying any L1 region of HPV in the sample. The amplicon from the L1 region may be analyzed to determine at least one of the presence of HPV, the type of the HPV and the risk category of any HPV. The compositions can include one or more primer sets for amplification of the L1 region of HPV.

Abstract: A first preferred embodiment includes a flow cytometer with a fluidic system to draw a sample fluid into an interrogation zone, a light source to emit light toward the sample fluid in the interrogation zone, an optic system to collect and detect at least one of a scattered light and a fluorescent light from the interrogation zone, and a processor. The flow cytometer, if properly boxed and labeled, complies with the parcel post requirements of the United States Postal Service. A second preferred embodiment includes the method of supplying a flow cytometer by shipping the flow cytometer via the United States Postal Service. A third preferred embodiment includes the method of servicing a flow cytometer by receiving the flow cytometer from a user via the United States Postal Service and servicing the flow cytometer.

Abstract: A system, method and program product for determining parallelism of an ion beam using a refraction method, are disclosed. One embodiment includes determining a first test position of the ion beam while not exposing the ion beam to an acceleration/deceleration electrical field, determining a second test position of the ion beam while exposing the ion beam to an acceleration/deceleration electrical field, and determining the parallelism of the ion beam based on the first test position and the second test position. The acceleration/deceleration electrical field acts to refract the ion beam between the two positions when the beam is not parallel, hence magnifying any non-parallelism. The amount of refraction, or lateral shift, can be used to determine the amount of non-parallelism of the ion beam. An ion implanter system and adjustments of the ion implanter system based on the parallelism determination are also disclosed.

Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.

Abstract: Presently described are microstructured articles such as a brightness enhancing film or optical turning film. The microstructured articles comprise a brightness enhancing polymerized structure comprising the reaction product of a composition comprising an organic component having at least one oligomeric urethane (meth)acrylate and surface modified silica nanoparticles.

Abstract: A method of exploiting a medical technology comprising: providing at least two types of medical systems incorporating the medical technology. Each of the systems has first capabilities useful in performing a first type of medical procedure, and second capabilities useful in performing a second type of medical procedure. One of the medical systems is offered in exchange for payment allowing access to both the first and second capabilities, and the other of the medical system is offered will full access to the first capabilities in exchange for payment, while access to the second capabilities are restricted and separately sold to the purchaser on an episodic basis.

Abstract: External power source, charger, system and method for an implantable medical device having therapeutic componentry and a secondary coil operatively coupled to the therapeutic componentry. A primary charging coil is capable of transcutaneously inductively energizing the secondary coil when externally placed in proximity of the secondary coil. Drive circuitry is operatively coupled to the primary charging coil for exciting the primary charging coil. A rechargeable power source is operatively coupled to the drive circuitry. A secondary recharging coil is operatively coupled to the rechargeable power source. A primary recharging coil is adapted to be coupled to a source of AC power which when placed in proximity of the secondary recharging coil can inductively energize the secondary recharging coil in order to charge the rechargeable power source.

Abstract: Light-collimating films as well as other microstructured film articles are described that comprise a (e.g. UV) cured light transmissive film comprising the reaction product of a polymerizable resin composition. Polymerizable resin compositions are also described that comprise aliphatic urethane(meth)acrylate oligomer(s), bisphenol-A ethoxylated diacrylate(s), and a crosslinker having at least three (meth)acrylate groups.

Abstract: A new acoustic insulating sheet material comprises in laminar assembly a) a primary sound absorbing sheet, and b) a dense porous membrane that i) has an air-flow resistance of about 5000 rayls or less and ii) has an Acoustic Value Ratio as defined herein of at least 3000. Preferably, the membrane is about 200 micrometers or less in thickness, and more preferably is about 150 micrometers or less in thickness. Also, the Acoustic Value Ratio is preferably at least 7,000. The described membrane can also be used alone to acoustically insulate a space, e.g., by mounting it in planar array over an air gap and in position to attenuate noise from a noise source.

Abstract: A system for bi-directional power distribution line communication. The system is configured for data communication with an endpoint transceiver located at a customer premise. The system comprises a time server in electrical communication with the transceiver, the time server configured to retrieve the time. A substation controller is in electrical communication with a power distribution line. The substation controller includes a transceiver and a programmable circuit. The programmable circuit includes a substation clock. The programmable circuit is programmed to periodically retrieve the time from the time server to calibrate the substation clock to the retrieved time, and to control the transceiver to transmit the time to the endpoint transceiver.

Abstract: An apparatus and a computer-implemented method for processing data in a bus system component. The bus system component is configured to operate in one of an endpoint mode and a root complex mode. Responsive to configuring the bus system component to operate in endpoint mode, the data is processed through the bus system component according to an endpoint process. Responsive to configuring the bus system component to operate in root complex mode, the data is transferred through the bus system component according to a root complex mode. In an illustrative example, the bus system component is a peripheral control interconnect express component.

Abstract: Presently described are (e.g. brightness enhancing film) optical articles comprising the reaction product of a polymerizable resin and surface modified inorganic nanoparticles, methods of surface modifying inorganic nanoparticles, and surface modified inorganic nanoparticles. The surface treatment comprises at least one monocarboxylic acid having a refractive index of at least 1.50 and/or at least one monocarboxylic acid having a Mn of at least 200 g/mole and an ethylenically unsaturated group and/or at least one dicarboxylic acid.

Abstract: A progressing cavity pump (PCP) system that may be deployed in an existing well configuration without the need for a workover rig. A stator and tubing stop are first set in a conduit, such as production tubing, at a desired depth. In subsequent wireline runs, a pack-off and upper tubing stop are installed above the stator, which results in the stator assembly being set by tubing stops on top and bottom and results in the conduit above the PCP being isolated from the wellbore below. Installation of the system is completed by installing the rotor and by installing top-side drive equipment in the usual way. The PCP system allows the deployment of lift systems within existing well configurations without any element being deployed on tubing and provides the ability to retrofit a well with an insertable pump within existing tubing.

Abstract: A door has a core that includes a porous layer having a thickness and two opposing major surfaces. In one construction, the core also includes three fire-retardant layers, and two of the fire-retardant layers are separated by the porous layer. The porous layer and the fire-retardant layers are coupled together. Other constructions include one or more fire-retardant layers in balanced or unbalanced placement around the porous layer.

Abstract: A vacuum adhesion-gripping surface is provided by an array of miniature suction cups. The surface is provided on a glove or other object for which an improved grip is desired. The miniature suction cups are of very small sizes and high densities. The vacuum adhesion micro suction cups are formed with a tooling structure having a pair of plates. A first plate includes a plurality of holes and a second plate includes a plurality of pins. When the plates are placed together, small cavities are created between the holes and pins for forming an array of vacuum adhesion micro suction cups using a molding or similar process. Alternatively a glove, such as a medical glove, utilizing the micro suction cup gripping design can be made using a dipping process.

Abstract: Apparatus and methods for practicing telemedicine in the form of software systems acting over a network and kits containing laboratory supplies and equipment to organize the laboratory operations and interpret the results of molecular diagnostic testing are disclosed. At least two computers in communication over the Internet or other network are used, a remote computer located at a remote site and a central server located at a central site. The remote site may be geographically distant from the central site. A specimen is procured from a patient proximate to the remote site. Laboratory operations are conducted on the specimen at the remote site. The laboratory data resulting from the laboratory operations is interpreted by an expert reviewer who may be located at the central site, and a report is then transmitted back to the remote site.

Abstract: Conductimetric assay devices that have both low end and high end sensitivity are described. The geometric shape and/or arrangement of the capture zones make it possible for the assay devices to have both low end and high end sensitivity. Also described is a conductimetric assay device having a pre-capture zone to capture unbound analyte. The assay device overcomes the problem of flooding by the analyte.

Abstract: In general, the invention is directed to a patient programmer for an implantable medical device. The patient programmer may include one or more of a variety of features that may enhance performance, support mobility and compactness, or promote patient convenience.