Abstract: A charged particle beam source for a surface processing apparatus is disclosed. The charged particle beam source comprises: a plasma chamber; a plasma generation unit adapted to convert an input gas within the plasma chamber into a plasma containing charged particles; and a grid assembly adjacent an opening of the plasma chamber. The grid assembly comprises one or more grids each having a plurality of apertures therethrough, the one or more grids being electrically biased in use so as to accelerate charged particles from the plasma through the grid(s) to thereby output a charged particle beam, the major axis of which is substantially perpendicular to the plane of the grid assembly.

Abstract: The present invention provides novel, stable, processable and pharmaceutically acceptable salt forms of 2R,6R-hydroxynorketamine or 2S,6S-hydroxynorketamine with high aqueous solubility.

Abstract: An assistive device for standing tasks allows for a reduction of effort on the part of a user while engaged in tasks or activities that are stationary or nearly stationary that lessens the strain on the bones, joints, and muscles normally used for standing while ensuring a proper alignment of the pelvis and spine.

Abstract: An assistive device for standing tasks allows for a reduction of effort on the part of a user while engaged in tasks or activities that are stationary or nearly stationary that lessens the strain on the bones, joints, and muscles normally used for standing while ensuring a proper alignment of the pelvis and spine.

Abstract: Customer-device application sites (e.g., content presented via a progressive web applications) that are accessible via merchant-managed identifiers (e.g., identification codes) are described. An identification of a physical location associated with a merchant can be associated with an identification code. The identification code can be received from a computing device of a customer and, based at least in part on receiving the identification code, merchant data associated with the merchant can be caused to be presented via a web browser of the computing device of the customer. In an example, the merchant data can be presented via the web browser by a progressive web application downloaded onto the computing device of the customer via the web browser. An indication of an input received via the progressive web application can be received by the computing device of the customer and an operation based at least in part on the input can be performed.

Abstract: Disclosed are systems and methods that enable robust, universal authentication and network access control capabilities for networks having a variety of computing device types and end users that access and operate on the network. The systems permit verification of end user identity, confirmation that computing devices have sufficient resources to reliably operate on the network, and configuration of computing devices with required software applications. The systems and methods further enable real-time, intelligent monitoring of the tasks and functions performed by system end users. The systems provide an immersive experience that allows end users to teleport into the environment of other end users, including viewing another end user's computer desktop, listening to ongoing telephone conversations, viewing and analyzing contemporaneous images or video of an end user and the end user's work environment, and interacting with the end user to provide precision coaching and assistance.

Abstract: A wearable orthotic appliance to which at least one corrective element for correcting neuromuscular imbalances may be removably attached is made of fabric assembly held in compressive tension when worn by a user, the fabric assembly including a cavity or chamber into which the corrective element may be placed and secured at any of a plurality of continuously-adjustable positions. Maintenance of the corrective element position during use of the appliance may be assisted by establishing a compression gradient over selected areas of the appliance during assembly. The wearable orthotic appliance may be a shirt, vest, body suit, or other garment or article of clothing, and the corrective elements may be weights, electrodes, or other discrete elements whose therapeutic effect depends on proper positioning relative to the wearer's torso or other body parts.

Abstract: This invention relates to high concentration solid oral dosage forms of a ketamine metabolite selected from 2R,6R-hydroxynorketamine, 2S,6S-hydroxynorketamine, R-5,6-dehydronorketamine and S-5,6-dehydronorketamine.

Abstract: A sliding tray assembly for rack mounted equipment is disclosed. The sliding tray includes a sliding bracket assembly, an arm support bracket, a tray, and an arm. The sliding bracket assembly is configured to mount to a rack. The arm support bracket is configured mount at a back of the rack The tray is configured to slidably mount to the sliding bracket assembly and includes one or more surfaces configured to support a chassis. The arm is configured to direct fiber from a back of the rack to the tray. The arm includes multiple links pivotally joined together. The multiple links including a first link configured to be pivotally joined to the arm support bracket and a second link configured to be pivotally joined to the tray.

Abstract: Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.

Abstract: The present invention provides compounds of formula I useful as inhibitors of Tyrosine Kinase 2 (Tyk2) solid forms and compositions thereof, methods of producing the same, and methods of using the same in the treatment of Tyk2-mediated diseases.

Abstract: A sliding tray assembly for rack mounted equipment is disclosed. The sliding tray includes a sliding bracket assembly, an arm support bracket, a tray, and an arm. The sliding bracket assembly is configured to mount to a rack. The arm support bracket is configured mount at a back of the rack The tray is configured to slidably mount to the sliding bracket assembly and includes one or more surfaces configured to support a chassis. The arm is configured to direct fiber from a back of the rack to the tray. The arm includes multiple links pivotally joined together. The multiple links including a first link configured to be pivotally joined to the arm support bracket and a second link configured to be pivotally joined to the tray.

Abstract: The present disclosure relates to synthesis and characterization of novel polymorphic forms of Cyclo (-His-Pro) (“CHP”).

Abstract: Sulfasalazine salt compositions are provided. In some cases, the sulfasalazine salts have a crystalline form. The subject crystalline sulfasalazine salts can provide a water soluble form of the active compound that finds use in pharmaceutical compositions and therapeutic applications. The subject crystalline sulfasalazine salts can provide increased solubility as compared to the zwitterionic or free acid form of sulfasalazine. Also provided are pharmaceutical compositions including the subject sulfasalazine salt compositions. Methods of treating a neurological related disease such as refractory epilepsy using the subject crystalline sulfasalazine salts and pharmaceutical compositions are also provided.

Abstract: A photochromic multilayer laminate with excellent darkening and fade-back speed and an eyewear lens incorporating the laminate are described. The laminate comprises at least three layers of polyvinyl alcohol, in which the third layer, comprising polyvinyl alcohol and one or more photochromic materials, is positioned between the surfaces of the two other polyvinyl alcohol layers. In one embodiment, the laminate is free of polarizer components and polarizing coatings. In other embodiments, the photochromic materials in the third layer have a form selected from the group including nanodroplets, photochromic nanoparticles and encapsulated forms with a capsule size between about 20 and 500 nm. The laminate and the eyewear lens may have additional layers, elements and additives.

Abstract: A moveable joint including a first member and a second member moveably connected to the first member, a shape-memory-alloy member coupled to the first member and engageable with the second member, and a biasing member configured to bias the second member from a first position relative to the first member towards a second position relative to the first member. Movement of the second member between the first position and the second position is limited by the shape-memory-alloy member such that the position of the second member relative to the first member is determined by the shape of the shape-memory-alloy member.

Abstract: An assistive device for standing tasks allows for a reduction of effort on the part of a user while engaged in tasks or activities that are stationary or nearly stationary that lessens the strain on the bones, joints, and muscles normally used for standing while ensuring a proper alignment of the pelvis and spine.

Abstract: Disclosed are systems and methods that enable both the real-time monitoring and historical tracking of events and actions performed by disparate systems and software applications associated with a computing device that also permit insight into the relationships between such events and actions. The inventive systems and methods synchronously and asynchronously capture event data from various event sources associated with a computing device. The event data can be enriched before correlating associated event data into transactions resulting in telemetry information to provide a more accurate and complete picture of what activities the computing device is performing and how the computing device is utilized to accomplish particular tasks. This telemetry information enables the system to perform descriptive and predictive analytical processes as well as artificial intelligence that provide valuable insights to improve end user and system performance.

Abstract: Disclosed are systems and methods that enable secure authentication to a network and virtual environment setup. An end point computing device combines data input by a user with stored data to determine an IP address where login credentials can be transmitted for authentication. The end point device transmits system information to a provider front end computing device for authentication. In this manner, a user identity and the end point device can be authenticated without the need to store identifying information to the end point device or communicate with a provider's secure back end network. The provider devices determine permissions data that define the user's ability to interact with the provider's network. The provider front end device transmits settings data to the end point device that is used to connect to the provider's network and establish a virtual working environment.