Abstract: A device comprising a modified porous membrane is provided. The modified porous membrane comprises a polymer coating grafted to a porous membrane. The device is used for analyte detection from a biological sample using an immunoassay. The device comprises a sample application zone at one end of the device for applying a biological sample comprising a target analyte; and a detection zone present at another end of the device, downstream of the sample application zone for detecting the target analyte, wherein the detection zone comprises one or more first biomolecules immobilized on a modified porous membrane having a structure of Formula (I).

Abstract: A system and method for controlling an amount of outgassing caused by implanting ions into a photoresist disposed on a workpiece. The amount of outgassing is based on the species being implanted, the type of photoresist, the energy of the implant, and the amount of dose that has already been implanted, among other effects. By controlling the effective beam current, the amount of outgassing may be maintained below a predetermined threshold. By developing and utilizing the relationship between effective beam current, dose completed and rate of outgassing, the effective beam current may be controlled more precisely to implant the workpiece in the most efficient manner while remaining below the predetermined outgassing threshold.

Abstract: A water recovery system including a first fluid stream inlet providing for the flow of a first fluid stream, such as a humidified inlet gas, into the system and a second fluid stream inlet providing for the flow of a second fluid stream, such as a gas having a temperature greater than the humidified inlet gas, into the system. At least one contactor is in fluid communication with the first fluid stream inlet and the second fluid stream inlet.

Abstract: A device for rapid detection of a tuberculosis lipoarabinomannan (TB-LAM) is provided. The device includes a pre-concentrator unit for concentrating the TB-LAM comprising: an ion-exchange medium comprising one or more ligands configured to capture the TB-LAM from the source biological sample, wherein the captured-TB-LAM is eluted from the ion-exchange medium as an eluate comprising a concentrated form of TB-LAM; a cassette; a lateral flow assay unit disposed in the cassette; and an integration unit attached to the pre-concentrator unit and the cassette. The integration unit is configured to operatively couple and de-couple the pre-concentrator unit and the cassette. The pre-concentrator unit and the lateral flow assay unit disposed in the cassette are in a fluidic communication in a coupled form. The device for rapid detection of TB-LAM further comprises a dilutor unit.

Abstract: The disclosure describes methods of treating humans with Duchenne muscular dystrophy by providing doses of an AAV9 vector that expresses a mini-dystrophin protein in transduced muscle cells.

Abstract: A rapid detection method of a target biomolecule comprising an antigenic moiety is provided. The method includes providing a source biological sample comprising the target biomolecule; contacting the source biological sample to an ion-exchange medium; eluting the captured-target biomolecule from the ion-exchange medium as an eluate, and loading the eluate to a rapid diagnostic testing device comprising an antibody. The eluate comprises a concentrated form of the biomolecule in a solution having a salt concentration greater than 150 mM. A concentration of the target biomolecule in the eluate is in a range from about 2× to 25× compared to a concentration of the biomolecule in the source biological sample. The target biomolecule binds to the antibody under the salt concentration of greater than 150 mM. A device for rapid detection of target biomolecule is also provided.

Abstract: A system and method for controlling an amount of outgassing caused by implanting ions into a photoresist disposed on a workpiece. The amount of outgassing is based on the species being implanted, the type of photoresist, the energy of the implant, and the amount of dose that has already been implanted, among other effects. By controlling the effective beam current, the amount of outgassing may be maintained below a predetermined threshold. By developing and utilizing the relationship between effective beam current, dose completed and rate of outgassing, the effective beam current may be controlled more precisely to implant the workpiece in the most efficient manner while remaining below the predetermined outgassing threshold.

Abstract: A headborne attachment platform includes multiple rigid plates and straps of connecting material connecting the rigid plates in an assembly at independently selectable and pre-set distances apart from each other. The assembly of rigid plates is shaped and connected to sit adjacent to, and surround, the bone regions of a wearer's skull, and define an overall headgear shape and contour. The straps are more flexible than the rigid plates in directions perpendicular to the thickness of the straps, and the straps are inelastic in a direction of a length thereof. A tightening mechanism is configured to adjust a circumference of a headband region, and the rigid plates have mounting features configured to mount an outer helmet shell and/or a headborne device. The rigid plates are sufficiently rigid to support and maintain their three-dimensional shape when subjected to forces exerted upon them by the outer helmet shell or headborne device.

Abstract: The invention relates to a moisture-protected electrical connection between a flat conductor and an insulated cable with a different cross-section to this and a soldering point, wherein a stripped, exposed cable end is surrounded by a solder foot or a cable end sleeve at the soldering point and is in material contact with an end of the flat conductor, and also a protective body.

Abstract: The present invention relates to compounds as defined herein, which are activators of long form cyclic nucleotide phosphodiesterase-4 (PDE4) enzymes (isoforms) and to therapies using these activators. In particular, the invention relates to these activator compounds for use in a method for the treatment or prevention of disorders requiring a reduction of second messenger responses mediated by cyclic 3?,5?-adenosine monophosphate (cAMP).

Abstract: An electrospinning approach is disclosed for generating a dissolvable formulation of a reagent of interest in a nanoscale fiber medium. In one embodiment, the nanoscale fibers can incorporate and stabilize biological agents of interest, such as for storage at room temperature for extended periods. In one implementation, the fibers can be produced in a continuous manner and dissolve rapidly.

Abstract: The invention provides an anti-glare coating of wide bandgap nanostructured oxide material so as to reduce the dazzling reflections of sunlight and avoid light pollution generated by spacecraft. The coating provides selective electrodeposition of a nanostructured wide bandgap oxide material on the metal contact grid on the surface of a solar panel of a spacecraft or a satellite in which the metal contact grid constitutes the cathode, and the resulting nanostructures have a width and spacing less than the wavelength ‘?’ of the incident light or equal to ‘?/n’ with ? located between 180 nm and 8?m, and ‘n’ being the refractive index of the nanostructured material so that for angles of incidence between 0.01 and 90 degrees less than 0.5% of light is reflected.

Abstract: A sideboard loading attachment for a utility vehicle includes a pair of lift arms coupled to box sides of the vehicle, a crossbar extending between distal ends of the projection arms, and a pair of lift actuators for raising and lowering the lift arms, whose distal ends can extend rearwardly from the vehicle when fully extended. A cable hoist is coupled to the utility vehicle and has a cable reeved over a pulley at the crossbar. The cable hoist raises and lowers the cable at the crossbar, and the lift actuators actuate the lift arms to raise a load up forwardly over the box of the utility vehicle.

Abstract: The invention relates to a method for producing a pre-tinning arrangement on a conductive surface, wherein, for a temporally and/or spatially subsequent soldering process, a soldering tin preform or a soldering tin round blank having a predefined three-dimensional shape is connected to the conductive surface in a captive and transportation-stable manner. For this purpose, the soldering tin preform or soldering tin round blank is fixed onto the conductive surface by means of a tacking solder, wherein the melting temperature of the tacking solder is below the melting temperature of the soldering tin preform or soldering tin round blank.

Abstract: A water recovery system including a first fluid stream inlet providing for the flow of a first fluid stream, such as a humidified inlet gas, into the system and a second fluid stream inlet providing for the flow of a second fluid stream, such as a gas having a temperature greater than the humidified inlet gas, into the system. At least one contactor is in fluid communication with the first fluid stream inlet and the second fluid stream inlet.

Abstract: A carbon dioxide (CO2) capture system and method for removing CO2 from an inlet gas including a first fluid stream inlet providing for the flow of a first fluid stream, such as an inlet gas containing CO2, and a second fluid stream inlet providing for the flow of a second fluid stream, such as steam, an outlet providing for the flow of a CO2 depleted stream from the CO2 capture system, an outlet providing for the flow of a CO2 stream from the CO2 capture system and a concentrator in fluid communication with the first fluid stream. The system further including a first contactor and a second contactor. Each of the first contactor and the second contactor defining therein a first fluidically-isolated, sorbent-integrated, fluid domain for flow of the first fluid stream and CO2 adsorption and a second fluidically-isolated fluid domain for flow of the second fluid stream to assist in desorption.

Abstract: Systems, methods, and software are disclosed herein for enhancing the content capture experience on computing devices. In an implementation, a combined user input comprises a voice signal and a touch gesture sustained at least partially coincident with the voice signal. An occurrence of the combined user input triggers the identification of an associated content object which may then be associated with a captured version of the voice signal. Such an advance provides users with a new framework for interacting with their devices, applications, and surroundings.

Abstract: A system and method for capturing and automated processing aerial images of structures to assess structural damage is disclosed. The system comprises a computing system used to obtain images of selected locations associated with known structures at different points in time before and after a natural disaster. The images are used to automatically create three-dimensional models that are used to detect the specific portions of a structure that may be damaged as well as the spatial extent of that damage. In addition, the imagery can be fed into a damage classifier that automatically classifies the degree of damage and generates accurate estimates of repair costs. The system and method may be deployed to quickly assess damage of structures in a disaster area and provide reports of the damage to homeowners and/or insurers.

Abstract: The inventive method provides for a method of p-type doping of Ga2O3 without adding impurity elements. Embodiments allow for significant simplification relative to extrinsic impurity element doping, and thus offers a reduced fabrication cost while being more temperature resistant since the defect dopants require higher temperatures to alter their impact. Certain methods disclosed provide for p-type gallium oxide formation via intrinsic defect doping, without requiring the addition of impurity elements which provide significant simplification relative to the existing state of the art approaches providing more temperature and radiation resistance, while offering a reduced fabrication cost.