Patents by Inventor David A. Walsh

David A. Walsh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS TO PREPARE TREPROSTINIL, THE ACTIVE INGREDIENT IN REMODULIN®
    Publication number: 20120283470
    Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
    Type: Application
    Filed: July 13, 2012
    Publication date: November 8, 2012
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Raju Penmasta, David A. Walsh
  • Process to prepare treprostinil, the active ingredient in remodulin
    Patent number: 8242305
    Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
    Type: Grant
    Filed: December 15, 2008
    Date of Patent: August 14, 2012
    Assignee: United Therapeutics Corporation
    Inventors: Hitesh Batra, Sudersan M. Tuladhar, Raju Penmasta, David A. Walsh
  • TREPROSTINIL PRODUCTION
    Publication number: 20120197041
    Abstract: The present invention is directed to a novel method for preparing a synthetic intermediates for treprostinil. Also described are methods of preparing treprostinil comprising utilizing novel intermediates described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil.
    Type: Application
    Filed: March 30, 2012
    Publication date: August 2, 2012
    Inventors: Hitesh BATRA, Raju PENMASTA, Vijay SHARMA, Sudersan M. TULADHAR, David A. WALSH
  • TREPROSTINIL PRODUCTION
    Publication number: 20120190888
    Abstract: The present invention is directed to a novel method for preparing a synthetic intermediates for treprostinil. Also described are methods of preparing treprostinil comprising utilizing novel intermediates described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil.
    Type: Application
    Filed: March 30, 2012
    Publication date: July 26, 2012
    Inventors: Hitesh Batra, Raju Penmasta, Vijay Sharma, Sudersan M. Tuladhar, David A. Walsh
  • AUTOMATED DOCUMENT GOVERNANCE
    Publication number: 20120110434
    Abstract: A method, system, and computer usable program product for automated document governance in a data processing environment are provided in the illustrative embodiments. A set of structured documents is received at an application executing in a computer in the data processing environment. A structure is recognized, parts of which structure are present in the documents in the set. A set of similarities in the documents in the set is summarized according to the recognized structure. A summarized information from the summarizing is presented such that a document governance action can be performed on a subset of the set of documents using the summarized information.
    Type: Application
    Filed: October 29, 2010
    Publication date: May 3, 2012
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Ramakrishna Janardhana Gorthi, Oriana Jeannette Love, David Walsh Palmieri, Jeffrey Tobias Robke
  • Locking mechanism with two-piece washer
    Patent number: 8157846
    Abstract: Locking mechanisms and methods of fixation, such as the fixation of a fixation device like a bone screw and of a rod to the spine. The locking mechanism includes a body, a rod seat and a set screw. The rod seat is configured to separate into two pieces when the rod exerts force on the top portion of the washer and the set screw limits movement of the washer toward the bottom of the locking mechanism.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: April 17, 2012
    Assignee: Ingenium S.A.
    Inventors: David S. Randol, David A. Walsh
  • TREPROSTINIL PRODUCTION
    Publication number: 20110319641
    Abstract: The present invention is directed to a novel method for preparing a synthetic intermediate for treprostinil via a stereoselective alkyne addition reaction. Also described are methods of preparing treprostinil comprising the alkyne addition reaction described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil.
    Type: Application
    Filed: June 2, 2011
    Publication date: December 29, 2011
    Inventors: Hitesh Batra, Raju Penmasta, Vijay Sharma, Sudersan M. Tuladhar, David A. Walsh
  • SPINAL FIXATION ASSEMBLY WITH INTERMEDIATE ELEMENT
    Publication number: 20110196430
    Abstract: A novel locking mechanism including a body and intermediate element and a method for locking the relative positions of a rod and a screw. The intermediate element is adapted to receive a rod and a head of a screw and is located between the rod and the head of the screw. The intermediate element has a non-circular shape such that at least one large non-contact area exists when the intermediate element is in contact with the head of the screw and the locking mechanism is fully engaged. The body is adapted to maintain the orientation of the non-circular intermediate element with respect to the body. The body also has at least one structure defining at least one distinct temporary stopping point for the intermediate element above the final locking position.
    Type: Application
    Filed: February 10, 2010
    Publication date: August 11, 2011
    Inventors: David A. Walsh, David S. Randol
  • Parametric generation using intersecting cavities
    Patent number: 7768695
    Abstract: A parametric device having a non-linear material (4) for generating an idler wave and a signal wave (16) in response to a pump wave (14), the pump, idler and signal waves being non-collinear, the device having a cavity (10, 11) resonant at the pump wavelength and means for varying the angle between the propagation directions of the pump and idler waves.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: August 3, 2010
    Assignee: The University Court of the University of St. Andrews
    Inventors: Malcolm H. Dunn, Cameron F. Rae, Tom J. Edwards, David J. M. Stothard, David Walsh
  • SPINAL FIXATION ASSEMBLY
    Publication number: 20100160980
    Abstract: A locking mechanism (100) and method of fixation, such as the fixation of a fixation device (104) like a bone screw and of a rod (106) to the spine. The locking mechanism (100) includes a body (102), an insert (108, 308), a rod seat (110, 310) and a set screw. The body (102) includes a bottom portion (114) configured to receive the fixation device (104) and the insert (108, 308) but prevents the insert (108, 308) and fixation device (104) from passing therethrough once the insert (108, 308) and fixation device (104) are engaged. The body (102) further includes a side portion (120) configured to receive the rod (106). Between the rod (106) and the insert (108, 308) is a rod seat (110, 310).
    Type: Application
    Filed: July 26, 2007
    Publication date: June 24, 2010
    Inventors: David A. Walsh, Karl Arthur Knobloch, Daniel R. Baker
  • SPINAL FIXATION ASSEMBLY
    Publication number: 20100152787
    Abstract: A locking mechanism (100) and method of fixation, such as the fixation of a fixation device (104) like a bone screw and of a rod (106) to the spine. The locking mechanism (100) includes a body (102), an insert (108, 308), a rod seat (110, 310) and a set screw. The body (102) includes a bottom portion (114) configured to receive the fixation device (104) and the insert (108, 308) but prevents the insert (108, 308) and fixation device (104) from passing therethrough once the insert (108, 308) and fixation device (104) are engaged. The body (102) further includes a side portion (120) configured to receive the rod (106). Between the rod (106) and the insert (108, 308) is a rod seat (110, 310).
    Type: Application
    Filed: July 26, 2007
    Publication date: June 17, 2010
    Applicant: Biotechni America Spine Group, Inc.
    Inventors: David A. Walsh, Carl Arthur Knobloch, Daniel R. Baker
  • LOCKING MECHANISM WITH TWO-PIECE WASHER
    Publication number: 20100023061
    Abstract: Locking mechanisms and methods of fixation, such as the fixation of a fixation device like a bone screw and of a rod to the spine. The locking mechanism includes a body, a rod seat and a set screw. The rod seat is configured to separate into two pieces when the rod exerts force on the top portion of the washer and the set screw limits movement of the washer toward the bottom of the locking mechanism.
    Type: Application
    Filed: July 24, 2008
    Publication date: January 28, 2010
    Inventors: David S. Randol, David A. Walsh
  • Coating for optimising output coupling of em radiation
    Patent number: 7626756
    Abstract: A coating between a nonlinear crystal and a silicon prism coupler, prevents transmission of radiation scattered within the crystal by filtering out frequencies outside the silicon bandgap to avoid free carrier absorption, but transmits THz frequencies that correspond to the bandgap.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: December 1, 2009
    Assignee: The University Court of the University of St. Andrews
    Inventors: Malcolm Dunn, Cameron F. Rae, Tom J. Edwards, David J. M. Stothard, David Walsh
  • TREPROSTINIL FORMULATION
    Publication number: 20090281189
    Abstract: There is provided a stable monohydrate form of treprostinil and pharmaceutical formulation comprising the same, method of making and using the same.
    Type: Application
    Filed: May 7, 2009
    Publication date: November 12, 2009
    Inventor: David A. Walsh
  • STABILIZATION RODS
    Publication number: 20090240284
    Abstract: A rod, such as that used for spinal stabilization, made of both metal material and elastomeric material. The rod may have a metal infrastructure, which may be non-cylindrical, to provide a desired stiffness for bending in at least one direction and may also have metal exterior surfaces for engaging metal components of spinal fixation locking mechanisms. In addition, the elastomeric material may only partially circumferentially encapsulate the metal material so that the metal material forms part of the surface of the rod.
    Type: Application
    Filed: March 24, 2008
    Publication date: September 24, 2009
    Inventors: David Scott Randol, David A. Walsh, Carl Arthur Knobloch
  • PROCESS TO PREPARE TREPROSTINIL, THE ACTIVE INGREDIENT IN REMODULIN
    Publication number: 20090163738
    Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
    Type: Application
    Filed: December 15, 2008
    Publication date: June 25, 2009
    Inventors: Hitesh BATRA, Sudersan M. TULADHAR, Raju PENMASTA, David A. WALSH
  • PARAMETRIC GENERATION USING INTERSECTING CAVITIES
    Publication number: 20090021825
    Abstract: A parametric device having a non-linear material (4) for generating an idler wave and a signal wave (16) in response to a pump wave (14), the pump, idler and signal waves being non-collinear, the device having a cavity (10, 11) resonant at the pump wavelength and means for varying the angle between the propagation directions of the pump and idler waves.
    Type: Application
    Filed: January 26, 2007
    Publication date: January 22, 2009
    Inventors: Malcolm H. Dunn, Cameron F. Rae, Tom J. Edwards, David J.M. Stothard, David Walsh
  • Coating for Optimising Output Coupling of Em Radiation
    Publication number: 20080298757
    Abstract: A coating (10) between a nonlinear crystal (5) and a silicon prism coupler (9), prevents transmission of radiation scattered within the crystal (5) by filtering out frequencies outside the silicon bandgap to avoid free carrier absorption, but transmits THz frequencies that correspond to the bandgap.
    Type: Application
    Filed: January 26, 2007
    Publication date: December 4, 2008
    Inventors: Malcolm Dunn, Cameron F. Rae, Tom J. Edwards, David J.M. Stothard, David Walsh
  • Strap securing device
    Patent number: D562728
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: February 26, 2008
    Assignee: Illinois Tool Works, Inc
    Inventors: Mark Downing, David A. Walsh, Dana Wright Gleason, Jr.
  • Vacuum cleaner
    Patent number: D620210
    Type: Grant
    Filed: July 9, 2009
    Date of Patent: July 20, 2010
    Assignee: Goodway Technologies Corporation
    Inventors: Joseph J Franzino, David Walsh