Abstract: A computer-implemented method for controlling a vehicle system of a host vehicle merging into a lane. The method includes determining an actual distance between the host vehicle and the one or more remote vehicles. The actual distance is a longitudinal distance between the host vehicle and the one or more remote vehicles. The method includes determining a safe distance for merging into the lane based on a relative position of the host vehicle to the one or more remote vehicles, a speed of the host vehicle, and a speed of the one or more remote vehicles. The safe distance is a second longitudinal distance between the host vehicle and the one or more remote vehicles. The method includes controlling the vehicle system of the host vehicle to assist a merge maneuver by the host vehicle according to the actual distance and the safe distance.

Abstract: The present invention relates to a process for preparing a decorative fired substrate such as ceramic, glass, brick, metal or metal enamel. The process includes a step of digitally applying a primer ink composition comprising a metal or metalloid ion component dissolved in a liquid matrix on selective locations of the substrate. The primer ink composition can be applied before or after the application of a color ink. By applying a primer ink composition, the color of the substrate is improved after the substrate is fired, and the manufacture cost is reduced compared with current industrial decorative ceramic tile processes.

Abstract: A streamlined method for purifying alpha-1-antitrypsin (AAT) from an AAT-containing protein mixture, such as Coh fraction IV precipitate, is provided. In the method of the invention, contaminating proteins are destabilized by cleavage of disulfide bonds with a reducing reagent, such as dithiol, which does not affect AAT. The destabilized proteins are then preferentially adsorbed on a solid protein-adsorbing material, without the addition of a salt as a precipitante. Spearation of the solid absorbent from the solution leaves a purified AAT solution that is directly suitabale for chromatographic purification, without the need for extensive desalting as in prior art processes. A process incorporating this method, which provides pharmaceutical grade AAT in high yield on a commercial scale, is also described.

Abstract: Techniques and apparatuses are described that enable radar attenuation mitigation. To improve radar performance, characteristics of an attenuator and/or properties of a radar signal are determined to reduce attenuation of the radar signal due to the attenuator and enable a radar system to detect a target located on an opposite side of the attenuator. These techniques are beneficial in situations in which the attenuator is unavoidably located between the radar system and a target, either due to integration within other electronic devices or due to an operating environment. These techniques save power and cost by reducing the attenuation without increasing transmit power or changing material properties of the attenuator.

Abstract: A computer-implemented method for controlling a vehicle system of a host vehicle merging with one or more remote vehicles, including receiving speed data transmitted from the one or more remote vehicles via a vehicular communication network and receiving position data of the one or more remote vehicles from the sensor system of the host vehicle that monitors an area around the host vehicle. Upon determining the one or more remote vehicles are in the area around the host vehicle based on the position data, determining a safe distance for merging into the lane based on a relative position of the host vehicle to the one or more remote vehicles. Further, controlling the vehicle system of the host vehicle according to an actual distance between the host vehicle and the one or more remote vehicles and the safe distance.

Abstract: A system for an electro magnetic oscillator tube with enhanced isotopes is disclosed herein having at least one magnetron layer. Each layer has a first magnet, a conduction block, and a second magnet of opposite polarity. The conduction block is disposed in a plane about an emitter of isotopic particles, where an opposite electrical polarity relative to the emitter forms between the emitter and the conduction block. The conduction block has an RF port, an interaction space in its inner periphery, and a polar array of resonant cavities forming along its outer periphery, and a diamond or similar material coating the conduction block surfaces. The system also has a connection between selected groups of resonant cavities at locations of like electrical polarity, wherein the connections have conductive strapping elements within the conduction block.

Abstract: The invention provides biodegradable implants sized for implantation in an ocular region and methods for treating medical conditions of the eye. The implants are formed from a mixture of hydrophilic end and hydrophobic end PLGA, and deliver active agents into an ocular region without a high burst release.

Abstract: The systems, devices, and methods presented herein use a blood pump to obtain measurements of cardiac function. The system can quantify the functioning of the native heart by measuring certain parameters/signals such as aortic pressure or motor current, then calculate and display one or more cardiac parameters and heart function parameters, such as left ventricular pressure, left ventricular end diastolic pressure, or cardiac power output. These parameters provide valuable information to a user regarding current cardiac function, as well as positioning and function of the blood pump. In some embodiments, the system can act as a diagnostic and therapeutic tool.

Abstract: Described herein are liquid formulations which deliver a variety of therapeutic agents, including but not limited to rapamycin, to a subject for an extended period of time; liquid formulations which form a non-dispersed mass when placed in an aqueous medium of a subject; liquid formulations comprising a therapeutic agent and a plurality of polymers; and methods for delivering therapeutic agents to a subject for an extended period of time using the liquid formulations. The liquid formulation may be placed in an aqueous medium of a subject, including but not limited to via intraocular or periocular administration. A method may be used to administer rapamycin to treat or prevent angiogenesis, choroidal neovascularization, or age-related macular degeneration in a subject.

Abstract: Particles emitted by radio-isotopic by-products of nuclear fission are used as a power source at the cathode of a magnetron system. Particles include high energy electrons having a large associated EMF. In the system a radial electrical vector E, between the cathode and anode, interacts with an axial magnetic vector B vector to produce an E×B force that rotates the particles about the system axis. These emissions are within a set range of velocities. The angular velocity and geometry of a rotating field, known as a space charge wheel (SCW), may be modulated by an external RF inputs to cavities of an anode block and the use of concentric biasing grids between the cathode and anode block. The SCW induces LC values into cavities of the anode, exciting them and producing electrons resonance which may be used to generate power.

Abstract: The invention provides biodegradable implants sized for implantation in an ocular region and methods for treating medical conditions of the eye. The implants are formed from a mixture of hydrophilic end and hydrophobic end PLGA, and deliver active agents into an ocular region without a high burst release.

Abstract: A cooling assembly includes a cooling chamber disposed inside of a turbine assembly. The cooling chamber directs cooling air inside an airfoil of the turbine assembly. The cooling assembly includes a metered channel fluidly coupled with the cooling chamber. The metered channel directs at least some of the cooling air out of the cooling chamber outside of a rail surface of the airfoil. The metered channel is elongated along and encompasses an axis. The metered channel has an interior surface with a distance between opposing first portions of the interior surface. The distance between the opposing first portions decreases at increasing distances along the axis from the cooling chamber toward the rail surface.

Abstract: A streamlined method for purifying alpha-1-antitrypsin (AAT) from an AAT-containing protein mixture, such as Coh fraction IV precipitate, is provided. In the method of the invention, contaminating proteins are destabilized by cleavage of disulfide bonds with a reducing reagent, such as dithiol, which does not affect AAT. The destabilized proteins are then preferentially adsorbed on a solid protein-adsorbing material, without the addition of a salt as a precipitante. Spearation of the solid absorbent from the solution leaves a purified AAT solution that is directly suitabale for chromatographic purification, without the need for extensive desalting as in prior art processes. A process incorporating this method, which provides pharmaceutical grade AAT in high yield on a commercial scale, is also described.

Abstract: A streamlined method for purifying alpha-1-antitrypsin (AAT) from an AAT-containing protein mixture, such as Coh fraction IV precipitate, is provided. In the method of the invention, contaminating proteins are destabilized by cleavage of disulfide bonds with a reducing reagent, such as dithiol, which does not affect AAT. The destabilized proteins are then preferentially adsorbed on a solid protein-adsorbing material, without the addition of a salt as a precipitante. Spearation of the solid absorbent from the solution leaves a purified AAT solution that is directly suitable for chromatographic purification, without the need for extensive desalting as in prior art processes. A process incorporating this method, which provides pharmaceutical grade AAT in high yield on a commercial scale, is also described.

Abstract: Disclosed are compositions, such as inkjet inks, for jetting onto a ceramic substrate, and associated methods and systems. The compositions comprise a pigment compound that is configured to be jetted on a ceramic substrate during a ceramic inkjet process to impart a color effect to the ceramic substrate, and a reduction agent which, when exposed to a firing temperature, reacts with the pigment compound to cause a reduction reaction. In some embodiments, the pigment compound comprises jettable copper particles, which can cause the fired composition to take on a red or oxblood color, which can be used for decoration.

Abstract: A computer-implemented method for controlling a vehicle system of a host vehicle merging with one or more remote vehicles, including receiving speed data transmitted from the one or more remote vehicles via a vehicular communication network and receiving position data of the one or more remote vehicles from the sensor system of the host vehicle that monitors an area around the host vehicle. Upon determining the one or more remote vehicles are in the area around the host vehicle based on the position data, determining a safe distance for merging into the lane based on a relative position of the host vehicle to the one or more remote vehicles. Further, controlling the vehicle system of the host vehicle according to an actual distance between the host vehicle and the one or more remote vehicles and the safe distance.

Abstract: Disclosed are compositions, such as inkjet inks, for jetting onto a ceramic substrate, and associated methods and systems. The compositions comprise a pigment compound that is configured to be jetted on a ceramic substrate during a ceramic inkjet process to impart a color effect to the ceramic substrate, and a reduction agent which, when exposed to a firing temperature, reacts with the pigment compound to cause a reduction reaction. In some embodiments, the pigment compound comprises jettable copper particles, which can cause the fired composition to take on a red or oxblood color, which can be used for decoration.

Abstract: Described herein are liquid rapamycin formulations. Described herein are methods of treating or preventing diseases or conditions, such as choroidal neovascularization, wet AMD and dry AMD, and preventing transition of dry AMD to wet AMD, using the liquid rapamycin formulations described herein.

Abstract: A 3D relief effect is created on a ceramic tile with an inkjet printer and an inkjet print head by printing a relief pattern with an effect ink having a low surface tension on the ceramic tile. The inkjet printer and inkjet print head apply an aqueous glaze slurry having a high surface tension on top of the effect ink. An image is printed on the glaze and the tile is fired. A difference in surface tensions causes the aqueous glaze to move away from the printed effect ink, resulting in a relief pattern in the image at locations of the printed relief pattern.

Abstract: Diseases and conditions associated with tissues of the body, including but not limited to tissues in the eye, can be effectively treated, prevented, inhibited, onset delayed, or regression caused by administering therapeutic agents to those tissues. Described herein are ophthalmic formulations that deliver a variety of therapeutic agents, including but not limited to rapamycin (sirolimus), analogs thereof (rapalogs) or other mTOR inhibitors, to a subject for an extended period of time. The ophthalmic formulations may be placed in an aqueous medium of a subject, including but not limited to intraocular or periocular administration, or placement proximate to a site of a disease or condition to be treated in a subject. A method may be used to administer a therapeutic agent to treat or prevent age-related macular degeneration, macular edema, diabetic retinopathy, uveitis, dry eye, or a hyperpermeability disease in a subject.