Abstract: Techniques for adjusting radiotherapy treatment for a patient in real time are provided. The techniques include operations comprising: obtaining, during delivery of a radiotherapy treatment fraction to a patient, one or more images of the patient at a first rate; generating patient motion information at a second rate based on the one or more images obtained at the first rate; receiving, during delivery of the radiotherapy treatment fraction, radiotherapy treatment device settings at a third rate; computing, during delivery of the radiotherapy treatment fraction, dose delivered to the patient with a first level of accuracy based on the generated patient motion information and the radiotherapy treatment device settings; and determining, during delivery of the radiotherapy treatment fraction, a real-time measure of accumulated dose delivered to the patient with a second greater level of accuracy than the first level of accuracy using one or more prior dose computations.

Abstract: The present invention relates to An optical device (1), particularly for an ophthalmic device, comprising: a container (2) enclosing an internal space (3) of the container (2), wherein the internal space (3) is filled with a transparent liquid (L), and wherein the container (2) comprises a transparent bottom (21) and a transparent and elastically deformable membrane (22) opposing said bottom (21) such that the liquid (L) is arranged between the membrane (22) and the bottom (21), a deformable annular lens shaping element (4) connected to the membrane (22) so that a circumferential edge (41) of the lens shaping element (4) defines a central area (23) of the membrane (22) so that light can pass through the container (2) via the central area (23) and the bottom (21), wherein in a non-deformed state said edge (41) lies in a plane, and an adjustable spherical power and an adjustable cylindrical power, wherein for adapting the cylindrical power of the optical device (1), the lens shaping element (4) is configured to

Abstract: Techniques for adjusting radiotherapy treatment for a patient in real time are provided. The techniques include retrieving a reference plan that includes three-dimensional (3D) volume representation of information for the patient and a plurality of radiotherapy beam delivery segments; identifying a first portion of the 3D volume representation of information for a first beam delivery segment of the plurality of radiotherapy beam delivery segments that includes a volumetric portion of a target irradiated by the first beam delivery segment; accessing a deformation model representing patient deformation during a radiotherapy treatment fraction; deforming the first portion of the 3D volume representation of information based on the deformation model; and updating one or more parameters of a radiotherapy treatment device based on the deformed first portion of the 3D volume representation of information.

Abstract: The invention relates to a lens (1) having an adjustable focal length, comprising: a container (2) enclosing an internal space (3) of the container (2), wherein the internal space (3) is filled with a transparent liquid (L), and wherein the container (2) comprises a circumferential lateral wall (20) surrounding said internal space (3), wherein the lateral wall (20) is connected to a transparent cover element (21) and to a transparent and elastically deformable membrane (22) such that the liquid (L) is arranged between the membrane (22) and the cover element (21), an annular lens shaper (4) connected to the membrane (22) so that an inner circumferential edge (40) of the lens shaper (4) defines a central area (23) of the membrane (22) and light passing said area (23) is refracted depending on a curvature of said area (23), and an actuator configured to move the lens shaper (4) towards or away from the cover element (21) to adjust said curvature of said area (23) of the lens (1) and therewith the focal length of

Abstract: The invention relates to a method for manufacturing a customized optical element to adjust an optical property of an optical component, such as goggles, wherein the method comprises the steps of receiving customer data indicative of a visual defect a person and/or a desired visual correction of the optical component; determining, from the customer data, the shape of a first surface of an optical element to be manufactured, such that the optical component, when the optical element is applied to an optical surface of the optical component, compensates at least partially or entirely the visual defect of the person or exhibits the desired visual correction; manufacturing the optical element using a liquid material that when brought in shape, is solidified.

Abstract: The invention relates to a liquid lens (1) with an adjustable optical power comprising at least the following components: a lens volume (VL) with a first transparent liquid (L1) arranged between a first transparent membrane (21) and a second transparent membrane (22) opposite the first membrane (21), wherein the first membrane (21) has a first side (21-1) facing outwards the lens volume (VL) and a second side (21-2) facing in the opposite direction particularly toward the lens volume (VL), wherein the second membrane (22) has a first side (22-1) facing toward the lens volume (VL) and a second side (22-2) facing in the opposite direction particularly outward the lens volume (VL), a lens shaping element (3) arranged on the first membrane (21), the lens shaping element (3) having a circumferential aperture (3a) defining a lens area (21a) of the first membrane (21) having an adjustable curvature, a rigid transparent window element (5) connected to the second membrane (22) covering a window portion (22a) of the

Abstract: As part of managing delivery of a packet flow according to a reliable transport protocol that supports multi-path delivery, a sender splits data into multiple flow packets of a flow and sends at least some of the flow packets to a receiver on multiple paths of a network. The sender receives feedback metadata and updates an out-of-order (“OOO”) tracking window. The sender also determines a metric that quantifies degree of OOO delivery. In general, the metric measures the extent to which flow packets have been successfully delivered OOO after a “missing” flow packet. If a sufficient count or range of flow packets have been acknowledged as received OOO after the missing flow packet, the missing flow packet is likely to have been dropped—not merely delayed. Depending on the metric, the sender selectively resends to the receiver one or more unacknowledged flow packets.

Abstract: As part of managing delivery of a given packet flow according to a reliable transport protocol, a sender sends, to a receiver, a last flow packet among multiple flow packets of a flowlet. After sending the last flow packet but before satisfaction of a timeout condition for the last flow packet, the sender sends one or more end-of-flowlet (“EOF”) packets, which can be flush packets, query packets, or another type of packet. The sender receives, from the receiver, feedback metadata for the EOF packet(s) and updates a tracking window based at least in part on the feedback metadata. The sender selectively resends one or more unacknowledged flow packets according to the updated tracking window. In this way, the sender can quickly address any dropped packets or significantly delayed packets at the end of a flowlet, without waiting for the timeout condition to detect the dropped or delayed packets.

Abstract: The invention relates to a lens having an adjustable optical power comprising a container with a frame structure delimiting a lens volume and a reservoir volume, wherein the lens volume and the reservoir volume are fluidically connected and comprise a liquid, wherein both volumes have at least one opening that are laterally shifted to each other and wherein each opening is covered by two elastically deformable membrane portions, wherein in the space enclosed between the membrane portions for each opening another liquid enclosed in. The invention further teaches a piston structure that is arranged to adjust a pressure in the reservoir volume such as to control a focal strength of the lens volume.

Abstract: The invention relates to a lens having an adjustable optical power comprising a container with a frame structure delimiting a lens volume and a reservoir volume, wherein the lens volume and the reservoir volume are fluidically connected and comprise a liquid, wherein both volumes have at least one opening that are laterally shifted to each other and wherein each opening is covered by two elastically deformable membrane portions, wherein in the space enclosed between the membrane portions for each opening another liquid enclosed in. The invention further teaches a piston structure that is arranged to adjust a pressure in the reservoir volume such as to control a focal strength of the lens volume.

Abstract: The invention relates to an optical device (1) for enhancing the resolution of an image or for reducing speckle noise.

Abstract: The present invention relates to a liquid for an optical tuneable device, wherein the optical tuneable device comprises a volume and a membrane and wherein the volume is filled with a liquid comprising at least one compound of formula (I), at least one additive, particularly wherein the at least one additive is selected from the group of a protecting agent, a stabiliser, a tracer, a buffer and/or a surface tension adjustment agent.

Abstract: The invention relates to an optical device (1) for enhancing the resolution of an image or for reducing speckle noise.

Abstract: The invention relates to a tunable optical component (100) comprising a liquid chamber (101), a flexible membrane (1), a shaping element (3), and an actuator (2), wherein the liquid chamber (101) is filled with a liquid (102), the membrane (1) delimits the liquid chamber (101), the membrane (1) is attached to the shaping element (3), the shaping element (3) has a ring shape, wherein the shaping element (3) surrounds an optically active area (10) of the membrane (1), the actuator (2) comprises multiple piezo units (20), the piezo unit (20) is coupled to a counterpart (203) in a releasable force-fitting manner, the piezo unit (20) is arranged to move the counterpart (203), and wherein the relative movement of the counterpart (203) and the piezo unit (20) results in a movement of the liquid (102), which causes a change of an optical property of the optically active area (10).

Abstract: The present invention relates to a method for producing at least one optical component (1), comprising the steps of: a) Providing at least one cavity (2), wherein the at least one cavity (2) is delimited on a first side by a surface (3a) of a first membrane portion (3), wherein a shape of the first membrane portion (3) is adjustable; b) Filling a material (4) into the at least one cavity (2) for forming at least one optical component (1), such that the material (4) contacts a surface (3a) of the first membrane portion (3); c) Adjusting the shape of the first membrane portion (3); d) Curing the material (4) filled into the at least one cavity (2) so that the material (4) forms a first interface (e.g. a first optical surface) (1a) of the at least one optical component (1), which first interface (1a) comprises a shape defined by a shape of the surface (3a) of the first membrane portion (3).

Abstract: Protection of a first software application to be executed on an execution platform by adding at least one check module to the software application, wherein the check module, when being executed, checks at least a part of the code of the protected software application loaded in the memory and carries out a predefined tamper response in case the check module detects that the checked code was changed or ensures that the protected software application continues to function correctly in case the check module detects that the checked code was not changed; selecting a first code region of the first software application, said first code region provides a first functionality when being executed; amending the selected first code region of the first software application such that an amended first code region is generated to provide the protected software application; wherein the amended first code region, when being executed, still provides the first functionality but carries out an access to at least a part of the code

Abstract: A new, stable trimeric TNF? structure is disclosed with distorted symmetry which can bind to the TNFR1 receptor to attenuate signalling therefrom, which can be used in the treatment and/or prevention of diseases associated with the soluble TNF?/TNFR1 interaction. Membrane-bound TNF? is not affected in its ability to signal through TNFR2, and thus the new structure of TNF? may be used in therapies which do not significantly raise the risk of infection or malignancy.

Abstract: The invention relates to a liquid lens (1) with an adjustable optical power comprising at least the following components: a lens volume (VL) with a first transparent liquid (L1) arranged between a first transparent membrane (21) and a second transparent membrane (22) opposite the first membrane (21), wherein the first membrane (21) has a first side (21-1) facing outwards the lens volume (VL) and a second side (21-2) facing in the opposite direction particularly toward the lens volume (VL), wherein the second membrane (22) has a first side (22-1) facing toward the lens volume (VL) and a second side (22-2) facing in the opposite direction particularly outward the lens volume (VL), a lens shaping element (3) arranged on the first membrane (21), the lens shaping element (3) having a circumferential aperture (3a) defining a lens area (21a) of the first membrane (21) having an adjustable curvature, a rigid transparent window element (5) connected to the second membrane (22) covering a window portion (22a) of the

Abstract: Optical element (1) comprising a sealed volume (15), a first window (11), a second window (12) and a membrane (13), wherein the membrane (13) encloses the sealed volume (15) in lateral directions and the membrane (13) encloses the sealed volume (15) in directions perpendicular to lateral directions, or the first window (11) and the second window (12) enclose the sealed volume (15) in directions perpendicular to lateral directions, wherein the sealed volume (15) is deformable by tilting the first window (11) with respect to the second window (12), wherein the first window (11) and the second window (12) being spaced apart by a solid structure (14), and the solid structure (14) is arranged to guide a motion of the first window (11) with respect to the second window (12), so that a pressure in the sealed volume (15) is constant.

Abstract: Tunable optical device comprising an actuator, a transmission element, a mount and an optical component, wherein the optical component comprises a window member and a ring member, wherein an optical property of the optical component is adjustable by altering the position of the ring member with respect to the window member. The actuator is arranged to generate an actuation force along an axial direction, the transmission element is arranged to transmit the actuation force from the actuator to the optical component, the transmitted actuation force alters the position of the ring member with respect to the window member. The transmission element comprises a bridge portion and a meander portion, wherein the bridge portion couples the ring member to the actuator and the window member is attached to the mount, or the bridge portion couples the window member to the actuator and the ring member is attached to the mount.