Abstract: A notification center system receives a message from a message source, the message comprising a message body, the message body comprising parameter-value pairs. The notification center system processes the message body to obtain a contextual string from the parameter-value pairs, appends a source identifier to the message, the source identifier identifying the message source, and stores the message appended with the source identifier in a platform-neutral format in a message store. Utilizing the contextual string, the message is then grouped, with other message(s) or by itself, with a message thread. The message is provided to a delivery mechanism for presentation of the message under the message thread. Content-aware contextual visual indicators may be determined for the message thread and the message based on different orders of specificity. The message thread and the message can then be displayed with their corresponding content-aware contextual visual indicators to provide additional insights.

Abstract: The disclosure provides processes for preparing a compound of Formula (I):

Abstract: This invention relates to methods of treating or preventing viral infections caused by flaviviruses, such as dengue virus, yellow fever virus, West Nile virus or Japanese encephalitis virus or infections caused by Chikungunya virus (CHIKV). The methods involve the administration of retinoic acid analogues to subjects who have, are suspected of having a flavivirus infection or infection with CHIKV, or to those who are at risk of becoming infected with a flavivirus or becoming infected with CHIKV.

Abstract: An electronic trading system is configured to trade credit default swap (CDS) futures contracts on an open exchange. The CDS futures contract allows the buyer and seller isolate and trade the credit risk of a third party. The third pay may be a corporation, sovereign government, or any entity that issues bonds or notes. The CDS futures contract seller effectively pays the premium over time in increments determined by market rates and through the natural operation of the open market. The CDS futures contract buyer makes a contingency payment if the CDS futures contract goes in-the-money (ITM). Both sides of the contract are guaranteed by the exchange as a counterparty.

Abstract: This invention is directed to novel carbocyclic prolinamide derivatives of Formula (I), and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.

Abstract: An assembly for an electric vehicle charger. The assembly comprising an electric vehicle charger housing having a first side wall, a second side wall and a porous membrane providing gas communication between an interior and exterior of the housing. Arranged within the housing are one or more electronics modules, an output circuit, and a heat exchanger. The assembly also includes a first air channel located between the one or more electronics modules and the first side wall of the housing, the first air channel being in fluid communication with the output circuit and the heat exchanger, and a second air channel located between the one or more electronics modules and the second side wall of the housing, the second air channel being in fluid communication with the output circuit and the heat exchanger.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue at multiple regions of interest, concurrently or consecutively. The neuromodulation may result in tissue displacement, which may be observed through changes in one or more molecules of interest.

Abstract: Aspects of the disclosure relate to methods, apparatus, and systems for replacing a drive assembly of a turntable load station. A system includes a structural pier, a track formed on a top surface of the structural pier, a turntable, a bogie assembly detachably coupled to an underside of the turntable, the bogie assembly including a wheeled drive assembly, a swap rail mounted to a radial side surface of the structural pier, and a translating cartridge movably mounted to the swap rail in a serviceable orientation. The translating cartridge is configured to move along the radial side surface of the structural pier via the swap rail while in the serviceable orientation to an unloading position underneath the bogie assembly, pivot from the serviceable orientation to an upright functional orientation to couple with the wheeled drive assembly, and decouple the wheeled drive assembly from the bogie assembly.

Abstract: In one aspect, a cooling tower system is provided that includes an evaporative heat exchanger, a sensor configured to detect a parameter of evaporative liquid distributed onto the evaporative heat exchanger, and an evaporative liquid treatment system. The cooling tower system further includes a controller having a normal operating mode wherein the controller operates the evaporative liquid treatment system to treat the evaporative liquid upon a determination of inadequate evaporative liquid quality based at least in part on the parameter of the evaporative liquid. The controller has a failsafe operating mode wherein the controller changes operation of the cooling tower upon a determination that the operation of the evaporative liquid treatment system is unable to remedy the inadequate evaporative liquid quality.

Abstract: An electronic trading system is configured to trade credit default swap (CDS) futures contracts on an open exchange. The CDS futures contract allows the buyer and seller isolate and trade the credit risk of a third party. The third pay may be a corporation, sovereign government, or any entity that issues bonds or notes. The CDS futures contract seller effectively pays the premium over time in increments determined by market rates and through the natural operation of the open market. The CDS futures contract buyer makes a contingency payment if the CDS futures contract goes in-the-money (ITM). Both sides of the contract are guaranteed by the exchange as a counterparty.

Abstract: The present discussion relates to structures and devices to facilitate application of an ultrasound therapy beam to a target anatomic region in a replicable manner. In certain aspects, an alignment controller may be used to analyze images generated by an ultrasound transducer. The alignment controller may then send a communication to indicate the energy application device is positioned to provide therapy to the target region, or if the device needs to be repositioned. The alignment control of the energy application device provides guided repeatable targeting of the target anatomic region, even when in non-clinical settings.

Abstract: A haircare appliance has an air inlet, an air outlet, and an airflow generator for generating an airflow from the air inlet to the air outlet. The haircare appliance has a signal generator configured to generate a signal indicative of hair contacting the haircare appliance. The airflow generator includes a first operating mode in which the airflow generator generates airflow at a first flow rate, and a second operating mode in which the airflow generator generates airflow at a second flow rate greater than the first flow rate. The airflow generator is configured to operate in the first operating mode in the absence of the signal and in the second operating mode in the presence of the signal.

Abstract: The present invention relates to an improved ball tossing device that is portable and adjustable to accommodate a variety of different balls and lobbing preferences. This may be achieved through various features including some or all of the following: a ball feeding mechanism using a rotating disk with an offset feed channel to deliver balls to the ball tossing queue; a catapult arm that uses a motor/spring mechanism to toss balls in the queue out of the machine; an indexer feature for isolating the ball to be tossed from the other balls in the queue; and adjustable features that allow users to vary ball trajectory of the ball being tossed.

Abstract: An apparatus for use in assessing strength of at least one knee flexor muscle of a subject, the apparatus including a support, two securing members, each securing member securing a respective lower leg of the subject in a position that in use is substantially fixed relative to the support and at least one sensor, which in use senses a force indicative of the strength of the at least one knee flexor muscle in at least one leg of the subject while the subject performs an eccentric contraction of the at least one knee flexor muscle.

Abstract: A modular electronics assembly comprising: removable electronic modules comprising a module housing containing electronic circuitry and bearing a module electrical connector coupled to the electronic circuitry each removable electronic module having a first alignment formation; an enclosure having an interior dimensioned to contain the removable electronic modules therein, the enclosure including, one or more enclosure electrical connectors corresponding to one or more of the module electrical connectors for establishing a connection, guide members extending into the interior of the enclosure for guiding respective ones of the module housings toward the enclosure electrical connectors; second alignment formations each arranged to cooperate with a respective first alignment formation of the removable electronic modules for aligning module electrical connectors with enclosure electrical connectors to thereby establish connection; wherein the first alignment formations are positioned on the module housings to re

Abstract: An electric vehicle charging system comprising a Direct Current (DC) distributor, a site controller, one or more alternating current (AC)/DC rectifiers connected to the DC distributor and the site controller, and an electric vehicle charger having one or more DC/DC converters connected to the DC distributor and a charge controller in communication with the site controller and each of the one or more DC/DC converters. The one or more AC/DC rectifiers are decoupled from the one or more DC/DC converters.

Abstract: A tool, such as a tape measure, including a spring-based retraction system is shown. Various spring-based retraction system embodiments are configured to decrease the size occupied by the spring within the tape measure housing, which consequently reduces tape measure housing size providing a more compact tape measure. Various spring-based retraction system embodiments are configured to control retraction of the tape measure in a manner that reduces whip or otherwise controls tape blade retraction. Some retraction system embodiments utilize a reduction gear train, and others utilize a compression spring and a transmission system that converts rotational movement of the tape reel to axial movement, which compresses the spring.

Abstract: Techniques and devices are described for embedding data in an address stream on an interconnect, such as a memory bus. Addresses in an address stream indicate at least part of a location in memory (e.g., a memory page and offset), whereas data embedded in the address stream can indicate when metadata or other information is available to lend context to the addresses in the address stream. The indication of data in the address stream can be communicated using, for example, a mailbox, a preamble message in a messaging protocol, a checksum, repetitive transmission, or combinations thereof. The indication of data can be recorded from the address stream and may later be used to interpret memory traces recorded during a test or can be used to communicate with a memory device or other recipient of the data during testing or regular operations.

Abstract: A computer system may access data corresponding to a portfolio that comprises interest rate swaps and may calculate parameters for a compressed swap. The computer system may determine, based at least in part on the parameters for the compressed swap, a performance bond requirement attributable to the interest rate swaps. The computer system may compare the performance bond requirement to account data associated with a holder of the portfolio and may perform one or more additional actions based on the comparing.