Abstract: The embodiments of present invention provide processes for the large-scale preparation of 2,4,6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl]benzamide hemisuccinate, and formulations and product forms, such as tablets, made by these processes. Additionally, embodiments of the present invention provide tablets including 25 mg, 50 mg, 100 mg, or 200 mg free base equivalent of 2,4,6-trifluoro-N-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide hemisuccinate.

Abstract: Disclosed in some examples, are methods, systems, and machine-readable mediums in which application state is saved using in-memory versioning in a shared memory pool of disaggregated memory. By utilizing a disaggregated memory pool, the processing resources may be on separate devices than the memory those resources are using. As a result of this architecture, a failure of hardware of processing resources or an application does not necessarily also cause the hardware resources of the memory devices to fail. This allows a standby application executing on standby processing resources to quickly resume execution when a primary application fails by utilizing the memory pool assigned to the primary application in the memory pool.

Abstract: A notification center system receives a message from a message source, the message comprising a message body, the message body comprising parameter-value pairs. The notification center system processes the message body to obtain a contextual string from the parameter-value pairs, appends a source identifier to the message, the source identifier identifying the message source, and stores the message appended with the source identifier in a platform-neutral format in a message store. Utilizing the contextual string, the message is then grouped, with other message(s) or by itself, with a message thread. The message is provided to a delivery mechanism for presentation of the message under the message thread. Content-aware contextual visual indicators may be determined for the message thread and the message based on different orders of specificity. The message thread and the message can then be displayed with their corresponding content-aware contextual visual indicators to provide additional insights.

Abstract: The present invention provides compounds of Formula XA-1, XA-2, XA-3, XA-4, XA-5, or XA-6, or metabolites of Compound 1 or metabolites of a compound of Formula I, PA-I, or PA-III, including compositions and salts thereof, which are useful in the prevention and/or treatment of a disease or disorder such as T2DM, obesity, or NASH, as well as analytical methods related to the administration of Compound 1 or a compound of Formula I, PA-1, or PA-III.

Abstract: A vision system for a mobile robot, the vision system including: a lens module; an illumination system including a plurality of light sources; and a lens module holder. The lens module holder is positioned around the lens module and includes a reflective surface for reflecting light emitted from the illumination system away from the lens module.

Abstract: A BBQ Grill comprising two side assemblies each with a lower side panel, an upper side panel, each of the upper side panels being slideably received in respective lower side panels. Cross braces space the panels apart and a grill plate is adapted to detachably engage apertures in the upper side panels. The grill has legs that extend and retract associated with the lower side panels and the upper side panels have a handle assembly with a push button to set pawls of a latch plate at selected apertures associated with the lower side panel. The grill preferably includes a rear wall, a drip tray and fuel support configured with the grill plate to be assembled between the two side assemblies in cooperation with the cross braces selectively connecting the two lower side panels. Various accessories are disclosed. The grill can use wood, charcoal briquettes or gas.

Abstract: A handpad for protecting the hand during repetitive gripping and/or impact activities, such as batting practice. The handpad may be made from a padded, absorbent and elastic material such as neoprene. The handpad may be secured to the hand by one or both of an index-finger insertion section and a little-finger insertion section. The finger insertion sections may be configured as holes in the handpad, or as loops created by folding and connecting respective corners of the handpad material to the handpad.

Abstract: An access counter associated with a segment of a memory device is maintained. An access notification for a first line of the segment is received. An access type associated with the access notification is identified. A first value of the access counter is changed by a second value based on the access type. Based on the first value of the access counter, a memory management scheme is implemented.

Abstract: The present invention relates, inter alia, to a method of producing a co-precipitate comprising nickel, manganese and/or cobalt, and to a co-precipitate produced by the method. The method may be a method of producing a co-precipitate comprising at least two metals selected from nickel, cobalt and manganese, and comprise: (i) providing an aqueous feed solution comprising said at least two metals and at least one impurity; and (ii) adjusting the pH of the feed solution to between about 6.2 and about 11, so as to provide: (a) a co-precipitate comprising said at least two metals; and (b) a supernatant comprising said at least one impurity.

Abstract: A method of synthesizing a perimorphic framework by chemical vapor deposition of a perimorph around an oxyanionic template, followed by dissolution of the oxyanionic template in water or in an aqueous weak acid comprising an oxyanion.

Abstract: Described herein are paddlecraft such as kayaks modified to include a motor to assist the paddling action of a user of the paddlecraft. The paddlecraft has a motor driven propeller located in an elongated channel within a paddlecraft base which drives water flow from an inlet side to an outlet side of the motor driven propeller via the elongated channel to drive movement of the paddlecraft. At least one movement sensor may be located on the paddlecraft and motor driven propeller actuation is driven by a user when the at least one movement sensor senses paddling movement by the user. A network comprising multiple paddlecraft and movement sensor communication is also described along with a method of assisting a paddlecraft user to generate motion.

Abstract: A container adapter includes a first chamber. The first chamber is adapted to attach to a container. The container further includes a second chamber. The second chamber includes a sealing surface and a resealable interface disposed between the first chamber and the second chamber. The second chamber is exposed to an ambient environment.

Abstract: In one aspect, a heat rejection apparatus is provided including an evaporative heat exchanger and a primary fan operable to direct first ambient air into an air inlet, cause the first ambient air to interact with the evaporative heat exchanger to produce heated air, and discharge the heated air from an air outlet. The heat rejection apparatus includes a plume abatement fan operable to direct second ambient air into contact with the heated air downstream of the evaporative heat exchanger and a controller operably coupled to the primary fan and the plume abatement fan. The controller has a plume abatement mode wherein the controller operates the plume abatement fan to cause the plume abatement fan to direct the second ambient air into contact with the heated air to cool the heated air and abate plume.

Abstract: Systems, apparatuses, and methods for memory management are described. For example, these may include a first memory level including memory pages in a memory array, a second memory level including a cache, a pre-fetch buffer, or both, and a memory controller that determines state information associated with a memory page in the memory array targeted by a memory access request. The state information may include a first parameter indicative of a current activation state of the memory page and a second parameter indicative of statistical likelihood (e.g., confidence) that a subsequent memory access request will target the memory page. The memory controller may disable storage of data associated with the memory page in the second memory level when the first parameter associated with the memory page indicates that the memory page is activated and the second parameter associated with the memory page is greater than or equal to a threshold.

Abstract: A display device support arm comprises: a securing component; a first support arm element pivotally attached to the securing component and coupling to an attachment means for receiving a coupling mechanism, incorporating a load indicator, at the lower end of a second support arm element. At the other end thereof is an attachment head and a display mounting head rotatably secured thereto. The mounting head includes a toothed arcuate surface to which there is pivotally mounted a trigger adapted to move one or more locking blocks out of biased engagement with the arcuate surface. Constant friction joints, a modified securing foot with tool holder, a tilt mechanism; a display rotation lock operably coupled to a display mounting interface; interchangeable rail assemblies; display mounting brackets for attachment to the rail assemblies; and methods of installing a support arm and setting a tilt mechanism are also defined.

Abstract: Embodiments of the present disclosure relate to techniques for accurate positioning of an energy application device for neuromodulation treatment protocols. In one embodiment, a neuromodulation positioning patch is applied to a patient's skin. The energy application device is configured to couple to a frame of the neuromodulation positioning patch to position a transducer of the energy application device within an opening at a treatment position within the opening. In one embodiment, the frame is also configured to couple to a removable dock for an imaging probe that, when coupled to the removable dock and, in turn, the frame of the neuromodulation positioning patch, is configured to acquire image data through the opening to identify or verify a treatment position.

Abstract: A prosthetic valve may be formed to direct flow out of the outflow orifice toward a posterior portion of a heart wall. The prosthetic valve includes an expandable frame which may be covered with a cover that is suturelessly attached to the frame. The prosthetic valve may also include an outflow orifice size which is controlled. Methods of using these devices are also disclosed.

Abstract: Various implementations include a switch assembly that includes a housing and at least two printed circuit boards (PCBs) that are disposed within the housing and are axially arranged relative to each other. One or more force sensors are disposed on one of the PCBs, and, in some implementations, the one or more force sensors receive force input received by a touch overlay plate. Signals from the force sensors are processed to determine a magnitude, acceleration, and/or location of the force input, and a haptic feedback response is received by the touch overlay plate. The haptic feedback response is based on the force magnitude, acceleration, and/or location of input, according to some implementations. Axially arranging the PCBs reduces the footprint of the switch assembly and allows for the inclusion of more electrical components in the switch assembly, according to some implementations.

Abstract: A fuel cell electrical power generation system is described herein. The system uses a combustor to increase the pressure and temperature of exhaust gases from a fuel cell stack of the system. The combustor uses hydrogen from a hydrogen supply to provide fuel to the combustor. The increased temperature/pressure of the exhaust gases post combustion are used to rotate a turbine, which in turn rotates a compressor of a turbocharger. The compressor compresses incoming air to increase the power output and/or the efficiency of the system. An ebooster can be used in low load conditions, such as during a startup or during at time in which the electrical loading on the fuel cells is relatively low.