Abstract: Systems and methods are disclosed for determining a topology of a network comprising a plurality of intermediary devices and intermediary paths. One method includes transmitting probes having a TTL value with a destination set to a destination device; receiving, for each probe transmitted, a response including an IP address of a responding device; determining whether more than one responding device has responded to the probes; determining whether more than one responding device has been found for two previous transmissions of probes when more than one responding device has responded to the probes; and transmitting, for each more than one responding device, probes having a decreased TTL value with a destination set to one of the IP addresses of the more than one responding devices, when more than one responding device has been found for two previous transmissions.

Abstract: Systems and methods are disclosed for determining a topology of a network comprising a plurality of intermediary devices and intermediary paths. One method includes transmitting probes having a TTL value with a destination set to a destination device; receiving, for each probe transmitted, a response including an IP address of a responding device; determining whether more than one responding device has responded to the probes; determining whether more than one responding device has been found for two previous transmissions of probes when more than one responding device has responded to the probes; and transmitting, for each more than one responding device, probes having a decreased TTL value with a destination set to one of the IP addresses of the more than one responding devices, when more than one responding device has been found for two previous transmissions.

Abstract: The present invention relates to an integrated method and apparatus for providing a synthesis gas to a cryogenic separation unit installed for separating synthesis gas into products selected from carbon monoxide, crude hydrogen, methane-rich fuel and syngas with a particular H2:CO ratio. More specifically, the invention relates to the purification of synthesis gas routed to a downstream cryogenic separation unit and minimizing temperature disturbances in the separation unit.

Abstract: The disclosure relates to nucleic acids that contain modifications at the 5?-end, 3?-end or 5?-end and 3?-ends, and compounds that can be used to make the modified nucleic acids are disclosed. The modified nucleic acids have improved expression, lower immunogenicity and improved stability compared to unmodified nucleic acids.

Abstract: The disclosure relates to nucleic acids that contain modifications at the 5?-end, 3?-end or 5?-end and 3?-ends, and compounds that can be used to make the modified nucleic acids are disclosed. The modified nucleic acids have improved expression, lower immunogenicity and improved stability compared to unmodified nucleic acids.

Abstract: This application discloses a computing system to receive a specification of prototype wiring corresponding to a signal in a logical design of a wire harness, locate a section of a vehicle to include a portion of the wire harness corresponding to the signal in the logical design, and insert the prototype wiring into a physical design of the wire harness corresponding to the located section of the vehicle. The specification of the prototype wiring can identify a particular vehicle configuration and insert the prototype wiring into a physical design of the wire harness for the particular vehicle configuration. The computing system can receive constraints configured to control synthesis of the logical design into the physical design of the wire harness, and generate portions of the physical design of the wire harness based on the constraints, while retaining the prototype wiring that was inserted into the physical design.

Abstract: Systems and methods are disclosed for determining a topology of a network comprising a plurality of intermediary devices and intermediary paths. One method includes transmitting probes having a TTL value with a destination set to a destination device; receiving, for each probe transmitted, a response including an IP address of a responding device; determining whether more than one responding device has responded to the probes; determining whether more than one responding device has been found for two previous transmissions of probes when more than one responding device has responded to the probes; and transmitting, for each more than one responding device, probes having a decreased TTL value with a destination set to one of the IP addresses of the more than one responding devices, when more than one responding device has been found for two previous transmissions.

Abstract: This application discloses a computing system to receive a specification of prototype wiring corresponding to a signal in a logical design of a wire harness, locate a section of a vehicle to include a portion of the wire harness corresponding to the signal in the logical design, and insert the prototype wiring into a physical design of the wire harness corresponding to the located section of the vehicle. The specification of the prototype wiring can identify a particular vehicle configuration and insert the prototype wiring into a physical design of the wire harness for the particular vehicle configuration. The computing system can receive constraints configured to control synthesis of the logical design into the physical design of the wire harness, and generate portions of the physical design of the wire harness based on the constraints, while retaining the prototype wiring that was inserted into the physical design.

Abstract: Systems and methods are disclosed for determining a topology of a network comprising a plurality of intermediary devices and intermediary paths. One method includes transmitting probes having a TTL value with a destination set to a destination device; receiving, for each probe transmitted, a response including an IP address of a responding device; determining whether more than one responding device has responded to the probes; determining whether more than one responding device has been found for two previous transmissions of probes when more than one responding device has responded to the probes; and transmitting, for each more than one responding device, probes having a decreased TTL value with a destination set to one of the IP addresses of the more than one responding devices, when more than one responding device has been found for two previous transmissions.

Abstract: The invention provides methods and compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and compositions for improving overall gastrointestinal health or for decreasing symptoms of lactose intolerance by administering to subject in need thereof a prebiotic composition, optionally in combination with effective amount of a probiotic microbe or microbes.

Abstract: Provided are novel methods and compositions for administration of pharmaceuticals to subjects with dysphagia. Pharmaceuticals are associated with beads and administered with food, beverage or cosmetic to provide ease of administration to subjects with dysphagia. Environmental indicators are associated with beads for Quality Assurance.

Abstract: The disclosure relates to nucleic acids that contain modifications at the 5?-end, 3?-end or 5?-end and 3?-ends, and compounds that can be used to make the modified nucleic acids arc disclosed. The modified nucleic acids have improved expression, lower immunogenicity and improved stability compared to unmodified nucleic acids.

Abstract: Provided are novel methods and compositions for administration of pharmaceuticals to subjects with dysphagia. Pharmaceuticals are associated with beads and administered with food, beverage or cosmetic to provide ease of administration to subjects with dysphagia. Environmental indicators are associated with beads for Quality Assurance.

Abstract: The invention provides methods and compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and compositions for improving overall gastrointestinal health or for decreasing symptoms of lactose intolerance by administering to subject in need thereof a prebiotic composition, optionally in combination with effective amount of a probiotic microbe or microbes.

Abstract: A heat exchanger comprises a stack of mutually spaced apart plates. The plates are separated by respective spacings therebetween. Alternate spacings respectively provide a flow path for a first fluid and a second fluid. The heat exchanger further comprises a first header for inflow of the first fluid and a second header for outflow of the first fluid. The first and second headers are connected to the plate stack by flexible tubular ducting means.

Abstract: The invention provides methods and compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and compositions for improving overall gastrointestinal health or for decreasing symptoms of lactose intolerance by administering to subject in need thereof a prebiotic composition, optionally in combination with effective amount of a probiotic microbe or microbes.

Abstract: A method, system and program product for optimizing of the provisioning of systems. The method, system, computer program product for provisioning a system comprises steps of intercepting a request to provision a named system; calculating a number of named systems needed to give an overall provisioning success rate higher than a threshold success rate; and requesting parallel provisioning of the calculated number of named systems.

Abstract: The invention provides methods and pharmaceutical compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and pharmaceutical compositions for improving overall gastrointestinal health or for decreasing symptoms of lactose intolerance by administering to subject in need thereof a pharmaceutical composition comprising a prebiotic, optionally in combination with effective amount of a probiotic microbe or microbes.

Abstract: The invention provides methods and compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and compositions for improving overall gastrointestinal health or for decreasing symptoms of lactose intolerance by administering to subject in need thereof a prebiotic composition, optionally in combination with effective amount of a probiotic microbe or microbes.

Abstract: The invention provides methods and compositions for treating symptoms associated with lactose intolerance and for overall improvement in gastrointestinal health. Described herein are methods and compositions for improving overall gastrointestinal health or for decreasing symptoms of lactose intolerance by administering to subject in need thereof a prebiotic composition, optionally in combination with effective amount of a probiotic microbe or microbes.