Abstract: A drill rig having a longitudinal drilling axis, a front portion, and a rear portion can comprise a feedframe aligned with the longitudinal drilling axis, a first head assembly coupled to the feedframe and configured to rotate a drill string, and a rod holder proximate the front portion of the drill rig. A second head assembly can be movable on the feedframe along the longitudinal axis and can include a powered water swivel assembly comprising a spindle having an interior bore a drill rod connector at a first end of the spindle, a motor that is configured to rotate the spindle, a clutch configured to disengage the motor from the spindle, a gearbox that couples the motor to the spindle, and a water swivel that is configured to provide drilling fluid to the interior bore of the spindle.

Abstract: A method of operating an accessory drive system for a motor vehicle, wherein the accessory drive system includes one or more accessory components, a motor generator of the motor vehicle, and a flexible drive element configured to transmit a torque load between the one or more accessory components and the motor generator, includes determining a maximum permissible flexible drive element torque threshold, detecting an increase in torque demand on the flexible drive element, determining when the torque demand on the flexible drive element will exceed the flexible drive element torque threshold, and reducing the torque demand of one or more of the accessory components so that the flexible drive element torque threshold is not exceeded.

Abstract: An apparatus includes first and second pluralities of switches, a controller for controlling these switches, gate-drivers for driving switches from the first plurality of switches, and first and second terminals configured for coupling to corresponding first and second external circuits at corresponding first and second voltages. During operation, the controller causes the first plurality of switches to transition between states. These transitions result in the second voltage being maintained at a value that is a multiple of the first voltage. The controller also causes the second plurality of switches to transition between states. These transitions resulting in capacitors being coupled or decoupled from the second voltage. The gate drivers derive, from the capacitors, charge for causing a voltage that enables switches from the first plurality of switches to be driven.

Abstract: An application server predicts respiratory disease risk, rescue medication usage, exacerbation, and healthcare utilization using trained predictive models. The application server includes model modules and submodel modules, which communicate with a database server, data sources, and client devices. The submodel modules train submodels by determining submodel coefficients based on training data from the database server. The submodel modules further determine statistical analysis data and estimates for medication usage events, healthcare utilization, and other related events. The model modules combine submodels to predict respiratory disease risk, exacerbation, rescue medication usage, healthcare utilization, and other related information. Model outputs are provided to users, including patients, providers, healthcare companies, electronic health record systems, real estate companies and other interested parties.

Abstract: The present invention relates to processes and intermediates for preparing compounds of formula (IA), wherein R1, R4, R5, R6, and L1 are as defined herein. Compounds of formula (IA) have been found useful as EP4 receptor agonists useful in the treatment of glaucoma, osteoporosis, neuropathic pain, and related disorders.

Abstract: A method of selecting wavelengths of radiation for discriminating a first cell or tissue type from a different cell or tissue type is described. First and second sets of absorption spectra are obtained, each set comprising spectra obtained at a plurality of different spatial regions of the first cell or tissue type and of the different cell or tissue type, respectively. Sets of corresponding metrics are defined for the first and second sets of absorption spectra for each spatial region. Each metric comprises information corresponding to the absorption for at least two different wavelengths. The metrics in each set comprise different combinations of wavelengths. A characteristic value is generated for each metric. Distributions are generated for each metric using corresponding characteristic values for the first cell or tissue type and for the different cell or tissue type and compared to determine an extent of similarity.

Abstract: A bi-directional egress hatch for a passenger aircraft may allow passengers to rapidly and safely exit an overhead cabin of the aircraft onto the main deck, while allowing cabin crew to safely ascend into the overhead cabin if need be. Hatch panels may blend in with overhead bin doors and ceiling panels of the main cabin; the inner portions of the hatch panels (facing the overhead cabin) may include anti-skid portions and graspable handles for descending passengers. The hatch may be easily activated by a passenger with a single motion (or remotely activated, or autodeployed). Once activated, the hatch panels may swing open and a telescoping ladder may deploy from the inner portion to the main deck, remaining rigid once reaching the floor. Similarly, any barriers protecting the ladder from passengers in the overhead cabin may be released, granting access to the telescoping ladder.

Abstract: The present disclosure provides improved compositions and methods for T-cell-based immunotherapy employing a modified T cells obtained from the lymphatic system of normal and cancer patient donors. These cells can then be used to treat patients for a variety of different blood and solid tumor cancers.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for training a neural network having a plurality of network parameters and being configured to process an input data item to generate a feature representation comprising a values for each of a plurality of features of the input data item.

Abstract: A method of selecting wavelengths of radiation for discriminating a first cell or tissue type from a different cell or tissue type is described. First and second sets of absorption spectra are obtained, each set comprising spectra obtained at a plurality of different spatial regions of the first cell or tissue type and of the different cell or tissue type, respectively. Sets of corresponding metrics are defined for the first and second sets of absorption spectra for each spatial region. Each metric comprises information corresponding to the absorption for at least two different wavelengths. The metrics in each set comprise different combinations of wavelengths. A characteristic value is generated for each metric. Distributions are generated for each metric using corresponding characteristic values for the first cell or tissue type and for the different cell or tissue type and compared to determine an extent of similarity.

Abstract: Passenger rest compartments may be incorporated into remote areas of an aircraft, either in the overhead crown region or in lower lobe cargo decks. Each passenger rest compartment includes two-way audio communication with the flight deck and non-intrusive non-visual monitoring of the compartments and surrounding environment to determine passenger presence, absence, and general well-being as well as environmental safety. Rest compartments may be integrated into rest cabins in the overhead or lower lobe areas, the rest cabins accessible from the main passenger cabin via an entry vestibule providing dedicated enclosed paths to the overhead and lower cabins. Additional deployable egress hatches may allow passengers to rapidly return to the main deck from the overhead and lower lobe cabins in the event of an emergency. Selected passenger seats (e.g., partitioned or other premium seats) may include private access to passenger rest compartments.

Abstract: An oral hygiene device is provided. The oral hygiene device includes a body having a base and first and second opposing sides extending from the base and defining a gap there between. The device may further include a plurality of corresponding notch pairs, wherein each corresponding notch pair has a first notch positioned in the first opposing side and a second notch positioned in the second opposing side. The location of the notch pairs may coincide with a user's mouth and in particular to the position of the user's teeth within the mouth. As such, a fibrous material, such as floss, may be coupled to the device such that the material spans the gap between at least one of the corresponding notch pairs so that the material may be inserted into the spaces between the user's teeth when the device is placed into the user's mouth.

Abstract: The field of the present invention relates, in general, to apparatus and methods of knitting a material into a tubular form, where the length of such tubular form is not dictated by conventional distances between the knitting areas and the catch basins of integrated machines. In short, this invention increases the distal relationship between the needle-equipped element, which performs the knitting function, and the basin that catches the resulting tubular form of the material. The basin rotates synchronized with the rotation of the resulting tubular form. The separation facilitates the continuous production of a length of the resulting tubular form of the material. The tubular form thus can be longer than such length where, as taught in the prior art, the catch basin is fixed—as part of integrated machines—in close proximity with the element that performs the knitting.

Abstract: Passenger rest compartments may be incorporated into remote areas of an aircraft, either in the overhead crown region or in lower lobe cargo decks. Each passenger rest compartment includes two-way audio communication with the flight deck and non-intrusive non-visual monitoring of the compartments and surrounding environment to determine passenger presence, absence, and general well-being as well as environmental safety. Rest compartments may be integrated into rest cabins in the overhead or lower lobe areas, the rest cabins accessible from the main passenger cabin via an entry vestibule providing dedicated enclosed paths to the overhead and lower cabins. Additional deployable egress hatches may allow passengers to rapidly return to the main deck from the overhead and lower lobe cabins in the event of an emergency. Selected passenger seats (e.g., partitioned or other premium seats) may include private access to passenger rest compartments.

Abstract: A bi-directional egress hatch for a passenger aircraft may allow passengers to rapidly and safely exit an overhead cabin of the aircraft onto the main deck, while allowing cabin crew to safely ascend into the overhead cabin if need be. Hatch panels may blend in with overhead bin doors and ceiling panels of the main cabin; the inner portions of the hatch panels (facing the overhead cabin) may include anti-skid portions and graspable handles for descending passengers. The hatch may be easily activated by a passenger with a single motion (or remotely activated, or autodeployed). Once activated, the hatch panels may swing open and a telescoping ladder may deploy from the inner portion to the main deck, remaining rigid once reaching the floor. Similarly, any barriers protecting the ladder from passengers in the overhead cabin may be released, granting access to the telescoping ladder.

Abstract: An oral hygiene device is provided. The oral hygiene device includes a body having a base and first and second opposing sides extending from the base and defining a gap therebetween. The device may further include a plurality of corresponding notch pairs, wherein each corresponding notch pair has a first notch positioned in the first opposing side and a second notch positioned in the second opposing side. The location of the notch pairs may coincide with a user's mouth and in particular to the position of the user's teeth within the mouth. As such, a fibrous material, such as floss, may be coupled to the device such that the material spans the gap between at least one of the corresponding notch pairs so that the material may be inserted into the spaces between the user's teeth when the device is placed into the user's mouth.

Abstract: A method of determining the P. aeruginosa or related species infection status of a subject comprising: (i) providing a sample of material obtained from the subject; (ii) determining the level of one or more alkyl quinolones or metabolites thereof produced by P.

Abstract: Disclosed herein is a system and method for managing financial information. According to an embodiment, electronic purchase data is received from an electronic payment source. The received electronic purchase data is generated into one or more visual representation formats using a transformation server. Once the visual representation has been generated, the visual representation format is rendered using a display device.

Abstract: Disclosed herein is a system and method for managing financial information. According to an embodiment, electronic purchase data is received from an electronic payment source. The received electronic purchase data is generated into one or more visual representation formats using a transformation server. Once the visual representation has been generated, the visual representation format is rendered using a display device.

Abstract: Compositions and methods for inhibiting, treating, and/or preventing a B-cell neoplasm are provided.