Abstract: System and method for processing a safety signal in an autonomous vehicle. Safety signals are typically generated in response to the detection of unsafe conditions or are sent by the vehicle operator. In either case, the safety signals are conveyed using redundant communication paths. The paths include a computer network and a current loop. The safety signals are processed, thereby causing actuators (e.g., linkages) to manipulate input devices (e.g., articulation controls and drive controls, such as a throttle, brake, tie rods, steering gear, throttle lever, accelerator, or transmission shifter). The manipulation ensures the vehicle responds appropriately to the safety signals, for example, by shutting down the vehicle.

Abstract: Systems and methods for interruptible autonomous control of a vehicle. Autonomous control is achieved by using actuators that interact with input devices in the vehicle. The actuators (e.g., linkages) manipulate the input devices (e.g., articulation controls and drive controls, such as a throttle, brake, tie rods, steering gear, throttle lever, or accelerator) to direct the operation of the vehicle. Although operating autonomously, manual operation of the vehicle is possible following the detection of events that suggest manual control is desired. Subsequent autonomous control may be permitted, permitted after a prescribed delay, or prevented.

Abstract: System and method for tracking obstacles by an autonomous vehicle. Localization sensors (i.e., sensors to measure pitch, roll, and yaw, and systems including an inertial navigation system, a compass, a global positioning system, or an odometer) detect the position of the vehicle. Perception sensors (e.g., LIDAR, stereo vision, infrared vision, radar, or sonar) assess the environment about the vehicle. Using these sensors, locations of terrain features relative to the vehicle are computed and kept up-to-date. The vehicle trajectory is adjusted to avoid terrain features that are obstacles in the path of the vehicle.

Abstract: System and method for multi-modal control of a vehicle. Actuators (e.g., linkages) manipulate input devices (e.g., articulation controls and drive controls, such as a throttle, brake, accelerator, throttle lever, steering gear, tie rods, or transmission shifter) to direct the operation of the vehicle. Behaviors that characterize the operational mode of the vehicle are associated with the actuators. After receipt of a mode select command that dictates the operational mode of the vehicle (e.g., manned operation, remote unmanned tele-operation, assisted remote tele-operation, and autonomous unmanned operation), the actuators manipulate the operator input devices, in accordance with the behaviors, to affect the desired operational mode.

Abstract: This invention relates to new polypeptide compound represented by the following general formula (I): wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on ?-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.

Abstract: Heterocycle substituted ketoamide derivatives of Formula (I), wherein the substitutes A, D, A and R are defined as in claim in, which are useful as cathepsin K inhibitors are described herein. The described invention also includes methods of making such heterocycle substituted ketoamide derivatives as well as method of using the same in the manufacture of medicaments for the treatment of disorders, including osteoporosis, associated with an imbalance between bone resorption and formation which can ultimately lead to fracture.

Abstract: This invention relates to new lipopeptide compound represented by the following general formula (I) wherein R1, R2, R3, R4 and R5 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on ?-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or thereapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal. In particular, R4 is an alkyl moiety which is substituted with an eventually protected and/or further substituted selected from amino, carboxy, guanidino, heterocyclic-carbonyl, alkyl-carbamoyl.

Abstract: This invention relates to new polypeptide compound represented by the general formula (I) wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on ?-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystic carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.

Abstract: This invention relates to new polypeptide compound represented by general formula (I), wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on ?-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.

Abstract: This invention relates to new lipopeptide compound represented by the following general formula (I): Wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on ?-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.

Abstract: This invention relates to new lipopeptide compound represented by the following general formula (I): wherein R1, R2, R3, R4 and R5 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on ?-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystis carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.

Abstract: A method, system, and recording medium for operating a yellow-pages type directory comprising providing a central relational database resident on a web server, the database comprising a set of primary contact records, each primary contact record including a primary key and, for each primary contact record, a set of related data records comprising the primary key of the related primary contact record, the database comprising a set of subscriber to contact record relationships. Upon receipt of related data from a subscriber, the system and method update the related record for the primary contact corresponding to the subscriber. Upon receipt of a search request from a user, preferably a primary contact record is returned to the user and either at the user's option or automatically, the related information is returned.

Abstract: The calibration of an imaging system having a camera (20) for capturing colour data for a target object (carcass 10) includes a primary calibration to obtain a primary transform for RGB data to enable compensation for variations in the camera operation or characteristics, and a secondary calibration obtain a secondary transform to enable compensation for local lighting conditions during capture and processing of colour data for captured images to be analysed. The calculated primary transform relates the actual measured colour data to known standard colour data for the particular standard colour specimens (31). The standard colour specimens (31) are presented in an enclosure or hood (30) to the camera under controlled illumination and with extrancous or external light being excluded from illuminating the specimens. A preliminary calibration includes calibrating the primary calibration standard colour specimens and associated controlled light source against centralised laboratory standard colours.

Abstract: A dehydrated intraocular lens implant is first folded and then inserted into the eye through an incision in the eye. The folded dehydrated intraocular lens implant is then allowed to unfold, hydrate in the eye and expand to its desired dimensions. The intraocular lens implant is comprised of a polymer, wherein the polymer is flexible and elastic when dehydrated so as to facilitate the intraocular lens implant to be folded and inserted into the incision in the eye. The polymer also expansile when hydrated, such that after insertion into the eye, the intraocular lens implant hydrates and expands.

Abstract: This invention relates to new polypeptide compound represented by the general formula (I) wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial activities (especially, antifungal activities), inhibitory activity on &bgr;-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of infectious diseases including Pneumocystic carinii infection (e.g. Pneumocystis carinii pneumonia) in a human being or an animal.

Abstract: An aspiration flow modulation device (10, 20, 50) having an irrigation line component (14, 24, 52) and an aspiration line component (12, 22, 54). A fluid communication lumen (12, 28, 75) extends between the components so as to provide a flow of fluid to reduce pressure variations in the event that the aspiration line becomes occluded in use.

Abstract: An intraoocular lens implant (10) including an optic (12) and a haptic (20). The haptic (20) includes a first portion (22) extending outwardly in a first direction from the optic (12), a second portion (26) which has an outermost end (32), extending outwardly in a second opposing direction to the first portion (22), and a bend member (24) intermediate and interconnecting the first portion (22) and the second portion (26). An end of the first portion (22) remote from the bend member (24) is connected to the optic (12) at a haptic optic junction (29) and the outermost end (32) of the second portion (26) is located on a side of the haptic optic junction (29) opposite to the side on which the bend member (24) is located.

Abstract: The method and apparatus of the present invention may be utilized to interconnect multiple local area networks to a data processing network including both multiple network nodes having routing and functional capability within the data processing network and multiple endpoint nodes having only local address capability, while minimizing the amount of routing information which must be maintained within the data processing network. A concentrator node is established for interconnection between each of the multiple local area networks and the data processing network. The concentrator node includes a network node interface having routing and functional capability for an associated local area network and an endpoint node interface having local address capability.

Abstract: An intraocular irrigation/aspiration device (10) including a hollow shaft (12) with a distal tip portion (20) and a proximal portion (24). The shaft (12) includes a lumen (18) extending through the shaft (12) wherein the lumen (18) is of reduced cross-sectional area in the proximal portion (24) so as to regulate aspiration of fluid and reduce post occlusion surge phenomena. Preferably, the device (10) includes an outer sleeve (26) which is flexible so as to enable a small incision in the eye to engage closely with the shaft (12).

Abstract: An intraocular irrigation/aspiration device (10) including a hollow shaft (12) with a distal tip portion (20) and a proximal portion (24). The shaft (12) includes a lumen (18) extending through the shaft (12) wherein the lumen (18) is of reduced cross-sectional area in the proximal portion (24) so as to regulate aspiration of fluid and reduce post occlusion surge phenomena. Preferably, the device (10) includes an outer sleeve (26) which is flexible so as to enable a small incision in the eye to engage closely with the shaft (12).