Abstract: Embolic coil implant systems and methods whereby coils are mechanically detachable are disclosed. The coils include a retention element that may be releasably retained within the distal end of an implant tool. The implant tool may include a fulcrum configured to engage a first filament and prevent the release of the coil when the first filament is engaged. Alternatively, an urging means and aperture may be disposed within the sidewall of the implant tool, and a first filament may, in conjunction with the aperture and sidewall, releasably retain the coil until the first filament is withdrawn. The implant tool may also include an alignment member for aligning the first filament.

Abstract: A system includes a shared data center having at least one data storage unit and at least one processing unit. The shared data center is configured to service one, two, or more industrial automation systems. For each of the one, two, or more industrial automation systems, the shared data center is configured to receive process-related data associated from at least one local device in at least one local system, analyze the process-related data from the local device, and provide instructions to at least one client device associated with the local system.

Abstract: Nodulisporic acids (NAs) comprise a group of indole diterpenes known for their potent insecticidal activities; however, biosynthesis of NAs by its natural producer, Hypoxylon pulicicidum (Nodulisporium sp.) is exceptionally difficult to achieve. The identification of genes responsible for NA production could enable biosynthetic pathway optimization to provide access to NAs for commercial applications. Obtaining useful quantities of NAs using published fermentations methods is challenging, making gene knockout studies an undesirable method to confirm gene function. Alternatively, heterologous gene expression of H. pulicicidum genes in a more robust host species like Penicillium paxilli provides a way to rapidly identify the function of genes that play a role in NA biosynthesis. In this work, we identified the function of four secondary-metabolic genes necessary for the biosynthesis of nodulisporic acid F (NAF) and reconstituted these genes in the genome of P.

Abstract: Provided are methods and system for assessing a human subject's neurological and/or psychological status. The methods entail displaying visual tests to a human subject, wherein each of the visual tests includes a visual target signal, optionally with visual cue signals, for eliciting visual and, optionally, body part, movements by the subject. Following the display, the movements are then detected. The latency and/or correctness of such movements can then be used to assess the subject's neurological and/or psychological status. Also provided are methods and systems for assessing performance validity.

Abstract: A bone implant includes a proximal end, a distal end, a first portion extending between the proximal and distal ends having a maximum and minimum portion height, and a second portion extending between the proximal and distal ends having a maximum and minimum portion height. The second portion is connected to the first portion at the proximal end and the distal end and at least one of the first portion and the second portion is moveable relative to the other of the first portion and the second portion so as to transition the bone implant between a relaxed state wherein the first and second portions are separated by a first distance and a contracted state wherein the first and second portions are separated by a second distance different from the first distance. At least one of the proximal end and the distal end have the minimum portion height.

Abstract: A track system for use with a towed vehicle has an attachment assembly and a multi-member frame assembly. The multi-member frame assembly includes a primary frame member connected to the attachment assembly, at least one wheel-bearing frame member pivotably connected to the primary frame member about a pivot located within a recess, and at least one resilient bushing assembly located within the recess and engaging the pivot. The at least one bushing assembly is resiliently deformable in a circumferential direction to permit pivoting of the pivot with respect to the recess, and is fixedly connected within the recess to resiliently bias the pivot towards a rest position with respect to the recess. The track system further includes leading and trailing idler wheel assemblies rotatably connected to the at least one wheel-bearing frame member, and an endless track.

Abstract: A bone implant includes a proximal end, a distal end, a first portion extending between the proximal and distal ends having a maximum and minimum portion height, and a second portion extending between the proximal and distal ends having a maximum and minimum portion height. The second portion is connected to the first portion at the proximal end and the distal end and at least one of the first portion and the second portion is moveable relative to the other of the first portion and the second portion so as to transition the bone implant between a relaxed state wherein the first and second portions are separated by a first distance and a contracted state wherein the first and second portions are separated by a second distance different from the first distance. At least one of the proximal end and the distal end have the minimum portion height.

Abstract: The invention provides isolated achromosomal dynamic active systems (ADAS), including highly active ADAS. These ADAS provided by the invention can be obtained by a variety of means. Various associated methods of making and using these ADAS are provided.

Abstract: An energy control system (ECS) for controlling an energy storage system (ESS's) that includes energy storage devices(s) or an energy storage combination (ESDC's) including ?1 of the energy storage devices and ?1 of the energy storage combinations. A power conversion system is coupled to an output of the ESDC, and a transformer is coupled to an output of the power conversion system. The ECS includes an ECS server and an ESS adapter configured for providing an interface between ECS server and the ESS. The ECS server is configured for reading status data from the ESS and submitting schedules including selected charging and discharging times to the ESS, monitoring or displaying a variance between an expected performance of the ESS based on the schedules and an actual ESS performance, and responsive to the variance being determined to be above a predetermined threshold, sending an update of the schedules to the ESS.

Abstract: Doxorubicin is extracted from blood using anionic material, such as a resin comprising sulfonated polystyrene divinylbenzene beads, and polyethersulfone membrane, or both. After exposing the resin and/or membrane to blood in order to remove doxorubicin therefrom, the doxorubicin maybe extracted from the resin and/or membrane by exposing the material to an extraction solution, sonicating the extraction solution to enhance release of the doxorubicin, and repeating the exposure and sonication in order to remove substantially all of doxorubicin from the resin.

Abstract: The disclosure includes devices for assisting in performing an ankle arthroplasty on a non-resected bone surface of a tibia and/or a talus. The devices may include patient-specific mating surfaces configured to engage the non-resected bone surface in a single relative position relative to the non-resected bone surface. The patient specific nature of the mating surface portion may be generated in the devices prior to the devices being brought into contact with the bone. The devices may include various cutting guides and holes for receiving fasteners to fasten the devices to the bone. The devices may include various features to enhance the stability and/or surface area contact between the devices and the bones.

Abstract: Doxorubicin is extracted from blood using anionic material, such as a resin comprising sulfonated polystyrene divinylbenzene beads, and polyethersulfone membrane, or both. After exposing the resin and/or membrane to blood in order to remove doxorubicin therefrom, the doxorubicin maybe extracted from the resin and/or membrane by exposing the material to an extraction solution, sonicating the extraction solution to enhance release of the doxorubicin, and repeating the exposure and sonication in order to remove substantially all of doxorubicin from the resin.

Abstract: A distribution system that provides for multicast transmission of the most important data that is of highest interest and value to client applications including HMI stations, historians, trend views, alarm management functions, advanced process controls, peer-peer communications and supervisory control. A blast list containing the types of data that are to be collected is formulated and stored in a system server and sent to embedded controllers which then multicasts that data to the system server and all console stations in the system.

Abstract: A thromboembolic removal system for treating ischemic stroke, including a guide and occlusion catheter, a delivery and aspiration catheter, an aspiration pump, a thromboembolic receiver, and a thromboembolic separator.

Abstract: An integrated circuit design method includes receiving an integrated circuit design, and determining a floor plan for the integrated circuit design. The floor plan includes an arrangement of a plurality of functional cells and a plurality of tap cells. Potential latchup locations in the floor plan are determined, and the arrangement of at least one of the functional cells or the tap cells is modified based on the determined potential latchup locations.

Abstract: A method includes receiving information associated with one or more first alarms in a first control system and generating a graphical user interface containing information associated with a second control system. The method also includes presenting, in the graphical user interface, at least a portion of the information associated with the one or more first alarms. The method further includes receiving, from a user via the graphical user interface, an invocation of an alarm management function. In addition, the method includes performing the invoked alarm management function using at least one of the one or more first alarms. The alarm management function could include acknowledging, shelving, and/or filtering the at least one of the one or more first alarms. The first control system may not support acknowledging, shelving, and filtering of alarms, while the second control system may support acknowledging, shelving, and filtering of alarms.

Abstract: An integrated circuit design method includes receiving an integrated circuit design, and determining a floor plan for the integrated circuit design. The floor plan includes an arrangement of a plurality of functional cells and a plurality of tap cells. Potential latchup locations in the floor plan are determined, and the arrangement of at least one of the functional cells or the tap cells is modified based on the determined potential latchup locations.

Abstract: A method includes creating, in a secure platform, multiple securely-partitioned system sandboxes under control of at least one user associated with an industrial process control and automation system. Different system sandboxes are associated with different third parties who are not owners or operators of the industrial process control and automation system. The method also includes receiving content from the third parties in the system sandboxes. The method further includes receiving from the at least one user a selective activation of at least some of the content in the system sandboxes in order to place the at least some of the content into use by the industrial process control and automation system. The content could include equipment configurations for equipment associated with the industrial process control and automation system, and the equipment configurations could include control strategies and visualizations for the equipment.

Abstract: A system includes a shared data center having at least one data storage unit and at least one processing unit. The shared data center is configured to service one, two, or more industrial automation systems. For each of the one, two, or more industrial automation systems, the shared data center is configured to receive process-related data associated from at least one local device in at least one local system, analyze the process-related data from the local device, and provide instructions to at least one client device associated with the local system.

Abstract: A distribution system that provides for multicast transmission of the most important data that is of highest interest and value to client applications including HMI stations, historians, trend views, alarm management functions, advanced process controls, peer-peer communications and supervisory control. A blast list containing the types of data that are to be collected is formulated and stored in a system server and sent to embedded controllers which then multicasts that data to the system server and all console stations in the system.