Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: A contact originator is given a choice to enqueue the contact in multiple contact queues, to serve multiple needs or interests of the originator. If the contact reaches the head of the queue for the primary need while the contact is being serviced from a queue for a secondary need, the contact either remains at the head of the primary-need queue until the servicing at the secondary-need queue is completed, or a resource of the primary-need queue is conferenced in with the contact and the resource of the secondary-need queue so that the resources can serve both needs simultaneously.

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: The present invention is directed to a quantum dot nanoparticle-based universal neurotoxin biosensor having three components (a) a dendrimer-encapsulated quantum dot nanoparticle; (b) acetylcholinesterase; and (c) an acceptor fluorophore, wherein the quantum dot nanoparticle and the acceptor fluorophore linked to the acetylcholinesterase.

Abstract: The invention relates to a golf training glove with sensors for triggering a perceptible signal on an erroneous gripping technique of the golf club with glove fingers to accommodate the thumb, index finger, middle finger, ring finger and little finger. According to the invention, error signals with a correct gripping technique may be avoided, whereby the sensors are at least a on the glove fingers for accommodation of the index finger, middle finger and ring finger and the perceptible signal is triggered by an excessive gripping pressure. No sensor is arranged on the thumb of the golf training glove.

Abstract: A stamped crankshaft seal retainer plate is provided, including a molded encoder sensor support feature for mounting an encoder sensor of an engine speed sensing system. The use of a stamped crankshaft seal retainer plate reduces the cost of the retainer plate as well as the overall weight of the vehicle while precisely locating the encoder sensor for position and required air gap.

Abstract: A method of making an encoder for use in a speed sensor includes providing a metal tube. A material containing ferrite is then extruded over the metal tube to produce an encoder tube. The encoder tube is cut to a given length to form an encoder. The encoder is then magnetized within a magnetic field.

Abstract: The invention is directed to increasing the endurance of a tire by providing an oxidation shield strip located in the vicinity of a critical area of the tire. The oxidation shield strip acts as a local oxygen diffusion barrier.

Abstract: The present invention is directed to a quantum dot nanoparticle-based universal neurotoxin biosensor having three components (a) a dendrimer-encapsulated quantum dot nanoparticle; (b) acetylcholinesterase; and (c) an acceptor fluorophore, wherein the quantum dot nanoparticle and the acceptor fluorophore linked to the acetylcholinesterase.

Abstract: A process for preweakening the inside of an automotive trim piece cover layer of various constructions by use of a laser beam so as to enable formation of an air bag deployment opening in the trim piece formed at the time the air bag deploys. The laser beam impinges the inside surface of the cover to form a groove scoring or spaced perforations to form a preweakening pattern. A robot arm may be used to move a laser generator so as to form the preweakening pattern. The laser beam can be controlled in accordance with sensed conditions to achieve accurate preweakening, and may also be used to trim substrate panels and to perform other cutting operations.

Abstract: Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Abstract: A saw, such as a chop saw, a miter saw, a sliding saw, a compound miter saw, etc. In some constructions, the saw may include a miter adjustment assembly including a coarse adjustment assembly and a fine adjustment assembly. In some constructions, the saw may include a bevel adjustment assembly including a brake mechanism and a bevel detent assembly. In some constructions, the saw may include a dust collection assembly including a dust chute defining a dust both around the bevel arm. In some constructions, the saw may include a table having a top wall with a peripheral rim and a side wall depending from the top wall, and a base defining an opening in which the side wall is received and a ledge above which the rim is positioned. In some constructions, the saw may include elastomeric material covering a portion of the base, such as a bottom surface, a lateral surface, a grip surface, etc.

Abstract: An exemplary system for determining vehicle salvage value includes a valuation subsystem configured to communicate with one or more access devices over a data communication network. The valuation subsystem includes a bid module and a valuation module. The bid module is configured to solicit bids for a vehicle over the data communication network and to receive one or more bids for the vehicle. The valuation module is configured to set a salvage value of the vehicle based on at least one of the received bids. In some examples, the received bids include a high bid, and the valuation module is configured to set the salvage value approximately equal to the high bid. In some examples, the bid module is configured to solicit virtual bids in real time over the data communication network.

Abstract: A saw, such as a chop saw, a miter saw, a sliding saw, a compound miter saw, etc. In some constructions, the saw may include a miter adjustment assembly including a coarse adjustment assembly and a fine adjustment assembly. In some constructions, the saw may include a bevel adjustment assembly including a brake mechanism and a bevel detent assembly. In some constructions, the saw may include a dust collection assembly including a dust chute defining a dust both around the bevel arm. In some constructions, the saw may include a table having a top wall with a peripheral rim and a side wall depending from the top wall, and a base defining an opening in which the side wall is received and a ledge above which the rim is positioned. In some constructions, the saw may include elastomeric material covering a portion of the base, such as a bottom surface, a lateral surface, a grip surface, etc.

Abstract: A rotary hammer and a power tool. The rotary hammer is operable in an idle mode and a hammer mode and comprises a housing and a barrel positioned in the housing and having a forward portion. A ram is positioned within the barrel and is movable relative to the barrel between hammering positions and an idle position. In some aspects, a ram catcher assembly is positioned along the axis adjacent the forward portion of the barrel to releasably hold the ram in the idle position. The ram catcher assembly includes a friction member frictionally engageable with the ram and a damping member at least partially surrounding the friction member. As the ram moves to the idle position with a force, the damping member absorbs at least a portion of the force and the member applies friction to the ram.

Abstract: An arrangement for forming an opening in an auto interior trim panel or piece normally having no visible indication of the opening just prior to inflation of an inflatable air bag, allowing deployment of the air bag into the passenger compartment of vehicle, the arrangement including a linear element positioned below the skin of the trim panel or wheel cover in a pattern corresponding to the opening. In a first embodiment a heat generating element is employed as the linear element which when activated degrades the covering skin layer of the trim piece in pattern shape. In a second embodiment detonating cord enclosed in a metal tube is employed with a series of holes directing the energy of detonation to sever the panel skin material. In a third embodiment a split sleeve having explosive coating on the inside is used to create a flame front severing the panel skin in the appropriate pattern.

Abstract: A saw, such as a chop saw, a miter saw, a sliding saw, a compound miter saw, etc. In some constructions, the saw may include a miter adjustment assembly including a coarse adjustment assembly and a fine adjustment assembly. In some constructions, the saw may include a bevel adjustment assembly including a brake mechanism and a bevel detent assembly. In some constructions, the saw may include a dust collection assembly including a dust chute defining a dust both around the bevel arm. In some constructions, the saw may include a table having a top wall with a peripheral rim and a side wall depending from the top wall, and a base defining an opening in which the side wall is received and a ledge above which the rim is positioned. In some constructions, the saw may include elastomeric material covering a portion of the base, such as a bottom surface, a lateral surface, a grip surface, etc.