Patents by Inventor David Burkhart

David Burkhart has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11464854
    Abstract: The methods and compositions described herein relate to methods of immunization or stimulating an immune response, e.g., using agonists of TLR7 and/or TLR8 as antigens. The methods and compositions described herein have particular relevance to use in infants.
    Type: Grant
    Filed: March 23, 2018
    Date of Patent: October 11, 2022
    Assignees: Children's Medical Center Corporation, University of Montana
    Inventors: Ofer Levy, David Dowling, Helene Bazin-Lee, David Burkhart, Jay Evans, Alyson Jessica Smith
  • Patent number: 11469084
    Abstract: A thermal choke rod connecting a radio frequency source to a substrate support of a plasma processing system includes a tubular member having a first connector for connecting to an RF rod coupled to the substrate support and a second connector for connecting to an RF strap that couples to the RF source. A tubular segment extends between the first and second connectors. The first connector has a conically-shaped end region that tapers away from the inner surface thereof to an outer surface in a direction toward the tubular segment, and slits that extend for a prescribed distance from a terminal end of the first connector. The outer surface of the tubular segment has a threaded region for threaded engagement with an annular cap that fits over the first connector and reduces an inner diameter of the first connector upon contact with the conically-shaped end region of the first connector.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: October 11, 2022
    Assignee: Lam Research Corporation
    Inventors: Timothy S. Thomas, Vince Burkhart, Joel Hollingsworth, David French, Damien Slevin
  • Publication number: 20220241410
    Abstract: Lipidated oxoadenines of formula (I) are TLR7/8 receptor ligands useful for modulating immune responses. The compounds may have therapeutic application in the treatment of cancer, infectious diseases, allergy, or autoimmnune disorders.
    Type: Application
    Filed: May 22, 2020
    Publication date: August 4, 2022
    Inventors: Helene Bazin-Lee, David Burkhart, Jay Evans
  • Publication number: 20220144833
    Abstract: This invention relates inter alia to novel imidazoquinoline derivatives and their use in therapy, particularly as vaccine adjuvants.
    Type: Application
    Filed: January 24, 2022
    Publication date: May 12, 2022
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Helene G. BAZIN-LEE, Jay T. EVANS, David BURKHART, Michael COCHRAN, David A. JOHNSON
  • Publication number: 20220144865
    Abstract: This invention relates inter alia to novel imidazoquinoline derivatives and their use in therapy, particularly as vaccine adjuvants.
    Type: Application
    Filed: January 24, 2022
    Publication date: May 12, 2022
    Applicant: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: Helene G. BAZIN-LEE, Jay T. EVANS, David BURKHART, Michael COCHRAN, David A. JOHNSON
  • Patent number: 11274115
    Abstract: This invention relates inter alia to novel imidazoquinoline derivatives and their use in therapy, particularly as vaccine adjuvants.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: March 15, 2022
    Assignee: GLAXOSMITHKLINE BIOLOGICAL SA
    Inventors: Helene G. Bazin-Lee, Jay T. Evans, David Burkhart, Michael Cochran, David A. Johnson
  • Patent number: 11207404
    Abstract: The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: December 28, 2021
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: David Burkhart, Michael Cochran, Christopher W Cluff, Daniel Larocque, Helene G. Bazin-Lee, Julien St-Jean
  • Publication number: 20210277038
    Abstract: This invention relates inter alia to novel imidazoquinoline derivatives and their use in therapy, particularly as vaccine adjuvants.
    Type: Application
    Filed: September 5, 2016
    Publication date: September 9, 2021
    Applicant: GLAXOSMITHKLINE BIOLOGICALS, S.A.
    Inventors: Helene G. BAZIN-LEE, Jay T. EVANS, David BURKHART, Michael COCHRAN, David A. JOHNSON
  • Publication number: 20210139521
    Abstract: Disclosed herein are diaryl trehalose compounds and methods of use thereof, for example as vaccine adjuvants.
    Type: Application
    Filed: February 21, 2019
    Publication date: May 13, 2021
    Inventors: David Burkhart, George Ettenger, Jay Evans, Kendal T. Ryter, Alyson Smith
  • Publication number: 20200397911
    Abstract: The invention relates to isolated immunogenic peptides comprising a MHC class II T cell epitope, and immediately adjacent or separated from said epitope a H-X(0,2)-C-X(2)-[CST] or [CST]-X(2)-C-X(0,2)-H redox motif.
    Type: Application
    Filed: June 4, 2020
    Publication date: December 24, 2020
    Applicant: IMCYSE SA
    Inventors: Jean-Marie SAINT-REMY, Vincent Carlier, Luc Vander Elst, David Burkhart
  • Publication number: 20200369704
    Abstract: Disclosed herein are immunogenic trehalose compounds and methods of use thereof, for example as vaccine adjuvants.
    Type: Application
    Filed: March 1, 2019
    Publication date: November 26, 2020
    Inventors: David Burkhart, Jay Evans, Craig Johnson, Kendal T. Ryter, Alyson Smith, Walid Abdelwahab Marzouky Abdelwahab
  • Publication number: 20200345841
    Abstract: The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
    Type: Application
    Filed: April 15, 2020
    Publication date: November 5, 2020
    Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA
    Inventors: David BURKHART, Michael COCHRAN, Christopher W. CLUFF, Daniel LAROCQUE, Helene G BAZIN-LEE, Julien ST JEAN
  • Patent number: 10646566
    Abstract: The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
    Type: Grant
    Filed: March 9, 2016
    Date of Patent: May 12, 2020
    Assignee: GLAXOSMITHKLINE BIOLOGICALS S.A.
    Inventors: David Burkhart, Michael Cochran, Christopher W Cluff, Daniel Larocque, Helene G Bazin-Lee, Julien St Jean
  • Publication number: 20200108139
    Abstract: The methods and compositions described herein relate to methods of immunization or stimulating an immune response, e.g., using agonists of TLR7 and/or TLR8 as antigens. The methods and compositions described herein have particular relevance to use in infants.
    Type: Application
    Filed: March 23, 2018
    Publication date: April 9, 2020
    Applicants: THE CHILDREN'S MEDICAL CENTER CORPORATION, UNIVERSITY OF MONTANA
    Inventors: Ofer LEVY, David DOWLING, Helene BAZIN-LEE, David BURKHART, Jay EVANS, Alyson Jessica SMITH
  • Publication number: 20180318415
    Abstract: The invention relates to a composition comprising solid lipid nanoparticles (SLNs), wherein the SLNs comprise an aminoalkyl glucosaminide phosphate (AGP).
    Type: Application
    Filed: December 6, 2016
    Publication date: November 8, 2018
    Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA
    Inventors: David BURKHART, Jay T. Evans, Hardeep OBEROI, Yvonne M. YORGENSEN
  • Publication number: 20180228912
    Abstract: The invention relates to isolated immunogenic peptides comprising a MHC class II T cell epitope, and immediately adjacent or separated from said epitope a H-X(0,2)-C-X(2)-[CST] or [CST]-X(2)-C-X(0,2)-H redox motif.
    Type: Application
    Filed: October 16, 2015
    Publication date: August 16, 2018
    Applicant: IMCYSE SA
    Inventors: Jean-Marie Saint-Remy, Vincent Carlier, Luc Vander Elst, David Burkhart
  • Publication number: 20180036403
    Abstract: The present invention relates to immunogenic compositions and methods for producing them, and in particular, immunogenic compositions comprising a protein antigen cross linked to an oxoadenine adjuvant.
    Type: Application
    Filed: March 9, 2016
    Publication date: February 8, 2018
    Applicant: GLAXOSMITHKLINE BIOLOGICALS, SA
    Inventors: David BURKHART, Michael COCHRAN, Christopher W CLUFF, Daniel LAROCQUE, Helene G BAZIN-LEE, Julien ST JEAN
  • Patent number: 9827260
    Abstract: There is provided a composition comprising an aminoalkyl glucosaminide phosphate compound or a pharmaceutically salt thereof and a buffer for use as an immunomodulator.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: November 28, 2017
    Assignee: GLAXOSMITHKLINE BIOLOGICALS SA
    Inventors: David Johnson, David Burkhart, Nupur Dutta
  • Publication number: 20170333771
    Abstract: A disc tossing game for a plurality of players: This game consists of players tossing discs onto a base target component that is physically connected by hinging/casing components to a backstop component to form a game system. The backstop can be locked into a relatively perpendicular relationship to the base target. The base target and backstop planar surface pieces can be folded flat to each other for transport and storage. A carrying handle is built-in. Participating players, in turn, each toss a disc at the base target of the game system. The player whose disc ends up on the base target closest to the backstop for that turn of play wins all other discs tossed by other participants. This is a competitive game that is safe and can be played either indoors or outdoors by young or old.
    Type: Application
    Filed: May 19, 2016
    Publication date: November 23, 2017
    Inventor: David A. Burkhart
  • Publication number: 20170071967
    Abstract: A liposomal composition comprising a liposome and an aminoalkansulfonic buffer is described and claimed.
    Type: Application
    Filed: March 12, 2015
    Publication date: March 16, 2017
    Inventors: Nupur DUTTA, Hardeep OBEROI, David BURKHART, Jay T EVANS