Abstract: An automatic coupling system (10) for a locomotive (11). The automatic coupling system includes a means for detecting a coupling contact and for controlling locomotive systems such as throttle and brakes in response to such contact. The means for detecting contact may be a speed sensor (24), an accelerometer (26), a distance detector (28), and/or a wheel slip detector (30). The automatic coupling system may be integrated with a locomotive remote control system (22) to facilitate the coupling of a locomotive to a railcar (40) when the operator is not located in the locomotive cab.

Abstract: The present invention is directed to optical devices. More specifically, the disclosed devices include a film defining a periodic array of surface elements so as to give rise to surface plasmon polaritons. The film also includes at least a single aperture having a diameter less than the wavelength of light. In one embodiment, the surface elements can be an array of anisotropic apertures and the films can act as a polarizer. The disclosed devices can also include a material having a variable refractive index substantially adjacent to the metal film. For example, the refractive index of the adjacent material can vary according to some characteristic of the light incident to the device, for instance, the intensity or the angle of incidence of the light. In this embodiment, resonant coupling of incident light with the SPP, and hence transmittivity of the device, can depend upon the nature of incident light.

Abstract: A system and method to allow valid profiles in autonomic computing discover is presented. A client accesses a network and sends a profile information request to a central computing device, such as a server. The server identifies client properties, such as the client's location and a user functionality description which corresponds to the client's user. The server uses the identified client properties to select an appropriate master profile from a master profile look-up table. The server sends master profile information, such as the master profile's pathname and revision time, to the client. In turn, the client determines whether it already has a valid profile or whether it should download an up-to-date version. If the client requires an up-to-date profile version, the client downloads the master profile from the server and uses the downloaded profile for various computing tasks.

Abstract: The invention encompasses compounds having formula I-V and the compositions and methods using these compounds in the treatment of conditions in which modulation of the JAK pathway or inhibition of JAK kinases, particularly JAK3, may be therapeutically useful.

Abstract: A method and system for verifying binding of an initial trusted device to a secured processing system binds an initial device or replacement when no binding information is available from another device in the system. A platform credential is issued only when a valid binding is verified, by sending a proof of binding to a credential provider, such as the manufacturer. The method secures against security breaches that can occur when a device is removed from the system during the binding process. The binding information is generated in the device upon installation and includes system identification information so that at each initialization, upon return of binding information from the system to the device, the device can ensure that it is installed in the proper system and abort operation if the system does not match.

Abstract: The present invention provides methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds, as well as methods of treating, preventing or ameliorating symptoms associated with such diseases. Specific examples of autoimmune diseases that can be treated or prevented with the compounds include rheumatoid arthritis and/or its associated symptoms, systemic lups erythematosis and/or its associated symptoms and multiple sclerosis and/or its associated symptoms.

Abstract: Sterilization methods and apparatus are effective to achieve a 6-log reduction in CFUs of industry standard bacteria and bacterial spores, i.e., B. stearothermophilus and B. subtilis spores, by subjecting sterilizable materials to a chemical additive-containing carbon dioxide sterilant fluid at or near its supercritical pressure and temperature conditions. Most preferably, the chemical additive-containing supercritical carbon dioxide sterilant fluid is agitated during sterilization, e.g., via mechanical agitation or via pressure cycling.

Abstract: A method and system for backup and restore of a context encryption key (CEK) for a trusted device within a secured processing system maintains security of virtualized trusted device contexts, providing for replacement of a trusted device in the field. The CEK is encrypted along with a system identifier by a random number to yield a first result. The first result is again encrypted with a manufacturer public key. The resulting blob is stored along with the random number. To restore, the system sends the blob and the device ID to a server. The server obtains the first result by decrypting with the manufacturer private key, re-encrypts with the device public key and sends the new result back. The system sends the new result to the device along with the associated random number. The device decrypts the new result using its private key and decrypts the CEK using the random number.

Abstract: A method and system for storing to a server a private key that was created on a TCPA-enabled client computer by the user. The user's private key is wrapped in a server non-migratable public key and sent to the server. When the user wants to migrate the user private key to a TCPA-enabled client computer, the user sends a request to the server for the user's private key along with the user's personal migration data for user identification. The server wraps the user's private key in the TCPA-enabled client computer's non-migratable public key, and transmits this “blob” to the client computer, which unwraps the blob to reveal the user's private key.

Abstract: A system and method of providing increased security of a personal computer through the use of its operating system and initialization. The invention provides a security profile which indicates the level of authorization which the user has and the security exposure which a user will be permitted, which combines with a stored log of attempts to access the personal computer through the use of the password and the results of each attempt to provide a system where unsuccessful attempts will turn off the system. The system also includes a plurality of access levels so that some functions in the computer may be denied to a user but permitted to a system administrator. The access log also may include a record of physical security attacks or attempt, such as removing the covers of a personal computer.

Abstract: An apparatus, system, and method are disclosed for securing I/O communications between a blade and peripheral interface device. The apparatus includes a determination module, a source security module, and a source communication module. The determination module identifies I/O data configured for transmission to a destination module configured to receive secure I/O data. The source security module encrypts the I/O data to generate secured I/O data such that subsequent decryption of the secured I/O data is restricted to a destination module. The source communication module transmits the secured I/O data over a vulnerable communication link to the destination module. The vulnerable communication link comprises a message intercept vulnerability. The destination module is configured to unencrypt the secure I/O data for a destination device such as a display device.

Abstract: The present invention is directed to substituted pyridines, methods for their preparation and methods for their use in the treatment and/or prevention of mast cell related conditions.

Abstract: A computer system, method of operation, and program product which gives a clear indication to a user when a computer system has transitioned to a trusted state.

Abstract: A machinable austempered cast iron article has improved strength, machinability, fatigue performance, and resistance to environmental cracking. A method of making the machinable austempered cast iron article includes austenitizing an iron composition having a substantially pearlitic microstructure in an intercritical temperature range of between 1380° F. and 1500° F. This produces a ferritic plus austenitic microstructure. The ferritic plus austenitic microstructure is quenched into an austempering temperature range of between 575° F. and 750° F. within 3 minutes to prevent formation of pearlite. The ferritic plus austenitic microstructure is then austempered in the austempering temperature range of between 575° F. and 750° F. to produce a microstructure of a continuous matrix of equiaxed ferrite with islands of austenite. Finally, the microstructure of the continuous matrix of equiaxed ferrite with islands of austenite is cooled to ambient temperature to produce the machinable austempered cast iron article.

Abstract: In one embodiment of the present invention an oxygen iodine laser includes a gas mixing section. Ground state oxygen and a carrier gas are introduced into the first gas mixing section, sometimes separately. The laser includes a discharge region to generate at least said excited oxygen from the flow of the first gas mixing section. A sensitizer gas having a lower ionization threshold than ground state oxygen is also introduced into the first gas mixing section, such that electrons are more easily produced in the electrical generator. The laser system includes introducing a source of iodine into the excited singlet delta oxygen flow to generate a laser-active gas. In another embodiment a conditioner is placed into the gas mixing section to help mix the flow and/or introduce one or more of the aforementioned gases.

Abstract: A computer system contains selectively available boot block codes. A first boot block is of the conventional type and is stored in storage media such as flash ROM on a system planar with the processor of the computer system. A second boot block is located on a feature card and contains an immutable security code in compliance with the Trusted Computing Platform Alliance (TCPA) specification. The boot block on the feature card is enabled if the first boot block detects the presence of the feature card. The computer system can be readily modified as the computer system is reconfigured, while maintaining compliance with the TCPA specification. A switching mechanism controls which of the boot blocks is to be activated. The feature card is disabled in the event of a computer system reset to prevent access to the TCPA compliant code and function.

Abstract: In a network of workstations implementing a grid for sharing workstation resources while maintaining local workstation workloads, grid workloads are assigned to workstations depending on how busy they are with the local workload. CPU utilization is monitored at each workstation and grid workload is only accepted if it can be handled without impacting the interactive performance of the workstation and in alignment with the workstation user's preferences. Also, grid workloads may be categorized by the extent to which they tie up workstation resources and this categorization used as further input to the grid workload assignment process.

Abstract: The present disclosure provides 4-pyrimidineamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferative diseases such as tumorigenic cancers.

Abstract: The present disclosure provides 2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferate diseases such as tumorigenic cancers.