Abstract: Systems for processing queries may first determine correspondence between the parameters of the query and a set of existing data entries, a set of previous queries that have been received, or both the existing data entries and the previous queries. If the query parameters do not correspond to the data entries or pervious queries, correspondence is determined between the query parameters and group data that associates at least a subset the query parameters with a particular group that may generate a response to the query. The same group or the generated response may be used when similar queries are received. If the group transmits the query to a different group or if negative user feedback is received, the group data may be modified to indicate the different group or to remove the association with the initial group that received the query.

Abstract: Characterization of the binding dynamics at the interface between any two proteins that specifically interact plays a role in myriad biomedical applications. The methods disclosed herein provide for the high-throughput characterization of the specific interaction at the interface between two protein binding partners and the identification of functionally significant mutations of one or both protein binding partners. For example, the methods disclosed herein may be useful for epitope and paratope mapping of an antibody-antigen pair, which is useful for the discovery and development of novel therapies, vaccines, diagnostics, among other biomedical applications.

Abstract: Characterization of the binding dynamics at the interface between any two proteins that specifically interact plays a role in myriad biomedical applications. The methods disclosed herein provide for the high-throughput characterization of the specific interaction at the interface between two protein binding partners and the identification of functionally significant mutations of one or both protein binding partners. For example, the methods disclosed herein may be useful for epitope and paratope mapping of an antibody-antigen pair, which is useful for the discovery and development of novel therapies, vaccines, diagnostics, among other biomedical applications.

Abstract: According to some embodiments, apparatus and methods are provided. A connector attachment includes a housing, wherein the connector attachment is selectively connectable to a mobile device; and a first token stored within the connector attachment, wherein the first token is operative to execute a transaction with a second token. Numerous other aspects are provided.

Abstract: Systems for processing queries may first determine correspondence between the parameters of the query and a set of existing data entries, a set of previous queries that have been received, or both the existing data entries and the previous queries. If the query parameters do not correspond to the data entries or pervious queries, correspondence is determined between the query parameters and group data that associates at least a subset the query parameters with a particular group that may generate a response to the query. The same group or the generated response may be used when similar queries are received. If the group transmits the query to a different group or if negative user feedback is received, the group data may be modified to indicate the different group or to remove the association with the initial group that received the query.

Abstract: Characterization of the binding dynamics at the interface between any two proteins that specifically interact plays a role in myriad biomedical applications. The methods disclosed herein provide for the high-throughput characterization of the specific interaction at the interface between two protein binding partners and the identification of functionally significant mutations of one or both protein binding partners. For example, the methods disclosed herein may be useful for epitope and paratope mapping of an antibody-antigen pair, which is useful for the discovery and development of novel therapies, vaccines, diagnostics, among other biomedical applications.

Abstract: Systems for processing queries may first determine correspondence between the parameters of the query and a set of existing data entries, a set of previous queries that have been received, or both the existing data entries and the previous queries. If the query parameters do not correspond to the data entries or pervious queries, correspondence is determined between the query parameters and group data that associates at least a subset the query parameters with a particular group that may generate a response to the query. The same group or the generated response may be used when similar queries are received. If the group transmits the query to a different group or if negative user feedback is received, the group data may be modified to indicate the different group or to remove the association with the initial group that received the query.

Abstract: Characterization of the binding dynamics at the interface between any two proteins that specifically interact plays a role in myriad biomedical applications. The methods disclosed herein provide for the high-throughput characterization of the specific interaction at the interface between two protein binding partners and the identification of functionally significant mutations of one or both protein binding partners. For example, the methods disclosed herein may be useful for epitope and paratope mapping of an antibody-antigen pair, which is useful for the discovery and development of novel therapies, vaccines, diagnostics, among other biomedical applications.

Abstract: Characterization of the binding dynamics at the interface between any two proteins that specifically interact plays a role in myriad biomedical applications. The methods disclosed herein provide for the high-throughput characterization of the specific interaction at the interface between two protein binding partners and the identification of functionally significant mutations of one or both protein binding partners. For example, the methods disclosed herein may be useful for epitope and paratope mapping of an antibody-antigen pair, which is useful for the discovery and development of novel therapies, vaccines, diagnostics, among other biomedical applications.

Abstract: An acoustic delay measurement apparatus measures an audio delay introduced by an audio system. A programmable delay buffer, which introduces a programmable delay into the audio stream, receives an audio stream from an audio source and outputs a reference signal representing the audio stream. An adaptive filter is responsive to the reference signal to generate an estimate signal to match on convergence of the adaptive filter an audio signal output by the audio system, which is the audio stream delayed by an amount representative of the audio delay introduced by the audio system. A processor including a coefficient analysis block reads coefficients in the adaptive filter after convergence, computes a delay introduced into said estimate signal by the adaptive filter, and adds the computed delay to the programmable delay buffer to provide a measurement of the audio delay.

Abstract: Systems and methods for determining whether a data entry has deprecated may receive a query from a user device and provide a data entry responsive to the query. If user feedback associated with the response indicates that the response resolved the query, confirmation data that associates the data entry with the query parameters is generated. If the user feedback indicates that the response did not resolve the query, existing confirmation data is accessed to determine whether a previous association between the data entry and the parameters of the query was generated. If correspondence between the confirmation data and the query and response is determined, a notification indicating the deprecation of the data entry is generated and the data entry may be suppressed from future output.

Abstract: According to some embodiments, apparatus and methods are provided comprising a connector attachment including a housing, wherein the connector attachment is selectively connectable to a mobile device; and a first token stored within the connector attachment, wherein the first token is operative to execute a transaction with a second token. Numerous other aspects are provided.

Abstract: According to some embodiments, apparatus and methods are provided comprising a connector attachment including a housing, wherein the connector attachment is selectively connectable to a mobile device; and a first token stored within the connector attachment, wherein the first token is operative to execute a transaction with a second token. Numerous other aspects are provided.

Abstract: A system for processing queries from a user device may first generate an augmented query by determining weight values and synonyms for at least a portion of the parameters in the query, and adding or removing one or more query parameters. Correspondence between the augmented query and an existing set of data entries may be used to determine a subset of data entries that may be responsive to the query. Correspondence may then be determined between the augmented query and previous queries that were addressed by the subset of data entries, to determine a particular previous query having the greatest correspondence with the augmented query. The data entry associated with the particular previous query may be used to generate a response to the query received from the user device.

Abstract: Methods and systems for self-service checkout. In an embodiment, a mobile device processor of a consumer's mobile device recognizes that the consumer mobile device has been transported to a merchant store location, initializes a self-service checkout application which includes at least one merchant rule preventing the consumer from purchasing certain items, receives input data, displays information concerning at least one item, and receives an indication that shopping is completed. The method includes transmitting checkout data to a self-service checkout computer for transmission to a merchant server, receiving, from the merchant server via the self-service checkout computer, a transaction authorization message and merchant instructions, and displaying the transaction authorization message and the merchant instructions including instructions directing the consumer to proceed to a designated exit.

Abstract: An acoustic delay measurement apparatus measures an audio delay introduced by an audio system. A programmable delay buffer, which introduces a programmable delay into the audio stream, receives an audio stream from an audio source and outputs a reference signal representing the audio stream. An adaptive filter is responsive to the reference signal to generate an estimate signal to match on convergence of the adaptive filter an audio signal output by the audio system, which is the audio stream delayed by an amount representative of the audio delay introduced by the audio system. A processor including a coefficient analysis block reads coefficients in the adaptive filter after convergence, computes a delay introduced into said estimate signal by the adaptive filter, and adds the computed delay to the programmable delay buffer to provide a measurement of the audio delay.

Abstract: Methods and systems for self-service checkout. In an embodiment, a mobile device processor of a consumer's mobile device recognizes that the consumer mobile device has been transported to a merchant store location, initializes a self-service checkout application which includes at least one merchant rule preventing the consumer from purchasing certain items, receives input data, displays information concerning at least one item, and receives an indication that shopping is completed. The method includes transmitting checkout data to a self-service checkout computer for transmission to a merchant server, receiving, from the merchant server via the self-service checkout computer, a transaction authorization message and merchant instructions, and displaying the transaction authorization message and the merchant instructions including instructions directing the consumer to proceed to a designated exit.

Abstract: The present invention is directed to a method of sealing the free end of a hollow fiber membrane for use in a single header filtration module by dipping the end of the membrane into a low-viscosity light-curable adhesive and curing the adhesive. The invention further encompasses the resulting sealed hollow fiber membrane with a diameter that is only slightly larger than the diameter of the unsealed membrane.

Abstract: Embodiments of the disclosure enable a card issuer to deliver and deliver payment cards in an organized and secure manner. In one aspect, a computer-implemented method and system for delivering a payment card is provided. The method and system include identifying a location of a client device associated with a request for the payment card. A first zone about the client device is scanned for one or more objects in the first zone. A determination is made as to whether at least one predetermined object of the one or more objects is associated with the payment card. On condition that the at least one predetermined object is associated with the payment card, the payment card is delivered. Aspects of the disclosure enable a card issuer to activate and deliver payment cards in an organized and secure manner.

Abstract: A method for submitting preselected, customized data exchanged between a mobile device and a point of sale includes: establishing, by a communication module of a point of sale device, a communication connection between the point of sale device and a mobile computing device in geographic proximity to the point of sale device; receiving, by a receiving device of the point of sale device, a data signal electronically transmitted by the mobile computing device via the communication connection, wherein the data signal is superimposed with at least one custom item identifier; identifying, by a data identification module of the point of sale device, one or more preselected, customized menu options based on at least the at least one custom item identifier; and submitting, to an order processing module of the point of sale device, the identified one or more preselected, customized menu options.