Abstract: Disclosed are methods by which compounds/molecules capable of binding antigens, for example antibody type compounds/molecules, can be purified, extracted and/or selected. The methods may be used to purify, extract or select a specific type (or types) of binding agent from a mixed composition. The methods may be used to extract or purify specific binding agents from mixed compositions, which compositions comprise other agents capable of binding other antigens. The methods may find particular application as methods for the purification of blood group antigen antibodies.

Abstract: Authentication processing is provided which includes generating an authentication parameter as a function of a time-dependent input using a predetermined transformation having an inverse transformation. Multiple authentication modes are supported, with a bit-length of the time-dependent input of one authentication mode being different from a bit-length of the time-dependent input of another authentication mode. Generating the authentication parameter is dependent, in part, on whether the time-dependent input is of the one authentication mode or the other authentication mode. A time-dependent password including a character string is generated from the authentication parameter using another predetermined transformation having another inverse transformation. The time-dependent password is forwarded within the authentication system for authentication by an authenticator.

Abstract: Authentication processing is provided which includes generating an authentication parameter as a function of a time-dependent input using a predetermined transformation having an inverse transformation. Multiple authentication modes are supported, with a bit-length of the time-dependent input of one authentication mode being different from a bit-length of the time-dependent input of another authentication mode. Generating the authentication parameter is dependent, in part, on whether the time-dependent input is of the one authentication mode or the other authentication mode. A time-dependent password including a character string is generated from the authentication parameter using another predetermined transformation having another inverse transformation. The time-dependent password is forwarded within the authentication system for authentication by an authenticator.

Abstract: Implementations described and claimed herein provide systems and methods for an optical domain controller for managing and maintaining a record of network component configuration and interconnections. The optical domain controller detects changes in a configuration of optical network elements in response to a requested service from the network, coordinates additional changes in configurations to optical network elements that may be affected by the detected change, communicates with the optical network elements to incorporate the changes to the configurations of the network element, and stores the configurations and states of the network elements. The use of the optical domain controller may thus replace or supplement a database storing network configuration information by automatically managing changes to the network as new services are instantiated directly on the optical network elements.

Abstract: A technique for performing authentication to a hybrid-cloud service includes selectively applying varying authentication requirements based on whether a client device can be confirmed to be connected to a private intranet. The technique includes operating a set of local agents on one or more computing machines on the intranet. When a client device requests access to the hybrid-cloud service, the client device attempts to contact one or more of the local agents. If the client device succeeds in contacting a local agent, then the client device is confirmed to be connected to the private intranet and receives relatively trusting treatment during authentication. However, if the client device fails to contact at least one local agent, the client device is not confirmed to be connected to the private intranet and receives relatively less trusting treatment.

Abstract: Methods and systems for securing a data connection for communicating between two end-points are described herein. One of the end-points may be a server and the other of the end-points may be a client that wants to communicate with the server. The data connection may be secured based on a previously-established secure connection and/or a self-signed or self-issued certificate. In some variations, by using the previously-established secure connection and/or a self-signed or self-issued certificate, the secure communication between the server and the client may be conducted without using a third-party authentication service and without requiring a third-party CA to issue a certificate for the server.

Abstract: Implementations described and claimed herein provide systems and methods for a configurable optical peering fabric to dynamically create a connection between participant sites without any physical site limitations or necessity of specialized client and network provider equipment being located within such a facility. Client sites to a network may connect to a configurable switching element to be interconnected to other client sites in response to a request to connect the first client site with a second site, also connected to network, via the switching element. A request may trigger verification of the requested and, upon validation, transmission of an instruction to the switching element to enable the cross connect within the switching element. The first site and the second site may thus be interconnected via the switching element in response to the request, without the need to co-locate equipment or to manually install a jumper between client equipment.

Abstract: A method for mitigating intentional potential interruptions in data signal communication, the method comprising transmitting (S21) or receiving (S23) a data signal, determining when a portion of the data signal has been successfully transmitted (S22) or received (S24), when the portion of the data signal has been successfully transmitted or received, generating (S25) a transmission interruption signal, and in response to the transmission interruption signal, performing one or more maintenance operations, such as beamforming, that may potentially interrupt transmission or reception of the data signal.

Abstract: Pulling eyes are provided with integrated wiring systems suitable for installing conductors or cables. The pulling eyes may include body portions that define interior cavities that are sized to snugly engage outside portions of the conductors or cables. The body portions are sized to be deformably crimped onto the outside portions of the conductors or cables. The pulling eyes may also include head portions joined to the body portions, with the head portions defining apertures for receiving a strength member for installing the conductors or cables. These apertures place the interior cavities in communication with the exteriors of the pulling eyes.

Abstract: An extendable augmented reality (AR) system for recognizing objects. The AR system may incorporate plugins to improve the AR system's ability to recognize objects, such as by adding external matchable data or using external recognition algorithms. The plugins may be installed/activated dynamically by a user to expand the system's AR capabilities. The AR system may also incorporate plugins to improve the AR system's post-recognition features such as supplying a user with supplemental content or follow-up functionality. The AR system may filter communications with the plugins to centralize identification processes, to shield plugins, and to ensure plugins are only activated at appropriate times.

Abstract: An object of the present invention is to provide immunogenic compositions for protection against S. pneumoniae, in particular against S. pneumoniae serogroup 9, while limiting the number of conjugates. The present invention therefore relates to new immunogenic compositions for use in pneumococcal vaccines and to vaccination of human subjects, in particular infants and elderly, against pneumoccocal infections using said immunogenic compositions.

Abstract: Pulling eyes are provided with integrated wiring systems suitable for installing conductors or cables. The pulling eyes may include body portions that define interior cavities that are sized to snugly engage outside portions of the conductors or cables. The body portions are sized to be deformably crimped onto the outside portions of the conductors or cables. The pulling eyes may also include head portions joined to the body portions, with the head portions defining apertures for receiving a strength member for installing the conductors or cables. These apertures place the interior cavities in communication with the exteriors of the pulling eyes.

Abstract: Aspects of the present disclosure involve systems for providing multiple egress routes from a telecommunications network for a client of the network. In general, the system provides for a client of the network to receive intended packets of information through multiple connections to the network such that load balancing and failover services for traffic to the customer are provided. The process and system allows for telecommunications network to utilize a common next-hop value of announced border gateway protocol (BGP) routes to advertise multiple routes to reach a destination customer network or address. By utilizing a common next-hop value in the announced BGP information, the devices of the network may load balance communication packets to the destination customer or address among the multiple egress locations from the network, as well as providing fast failover to alternate routes when a failure at the network or customer occurs.

Abstract: Implementations described and claimed herein provide systems and methods for a configurable optical peering fabric to dynamically create a connection between participant sites without any physical site limitations or necessity of specialized client and network provider equipment being located within such a facility. Client sites to a network may connect to a configurable switching element to be interconnected to other client sites in response to a request to connect the first client site with a second site, also connected to network, via the switching element. A request may trigger verification of the requested and, upon validation, transmission of an instruction to the switching element to enable the cross connect within the switching element. The first site and the second site may thus be interconnected via the switching element in response to the request, without the need to co-locate equipment or to manually install a jumper between client equipment.

Abstract: The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumoccocal infections using said novel immunogenic compositions.

Abstract: Implementations described and claimed herein provide systems and methods for a configurable optical peering fabric to dynamically create a connection between participant sites without any physical site limitations or necessity of specialized client and network provider equipment being located within such a facility. Client sites to a network may connect to a configurable switching element to be interconnected to other client sites in response to a request to connect the first client site with a second site, also connected to network, via the switching element. A request may trigger verification of the requested and, upon validation, transmission of an instruction to the switching element to enable the cross connect within the switching element. The first site and the second site may thus be interconnected via the switching element in response to the request, without the need to co-locate equipment or to manually install a jumper between client equipment.

Abstract: An object of the present invention is to provide immunogenic compositions for protection against S. pneumoniae, in particular against S. pneumoniae serogroup 9, while limiting the number of conjugates. The present invention therefore relates to new immunogenic compositions for use in pneumococcal vaccines and to vaccination of human subjects, in particular infants and elderly, against pneumococcal infections using said immunogenic compositions.

Abstract: The present invention relates to new immunogenic compositions comprising conjughated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates) and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumococcal infections using said novel immunogenic compositions.

Abstract: Implementations described and claimed herein provide systems and methods for an optical domain controller for managing and maintaining a record of network component configuration and interconnections. The optical domain controller detects changes in a configuration of optical network elements in response to a requested service from the network, coordinates additional changes in configurations to optical network elements that may be affected by the detected change, communicates with the optical network elements to incorporate the changes to the configurations of the network element, and stores the configurations and states of the network elements. The use of the optical domain controller may thus replace or supplement a database storing network configuration information by automatically managing changes to the network as new services are instantiated directly on the optical network elements.

Abstract: Aspects of the present disclosure involve systems for providing multiple egress routes from a telecommunications network for a client of the network. In general, the system provides for a client of the network to receive intended packets of information through multiple connections to the network such that load balancing and failover services for traffic to the customer are provided. The process and system allows for telecommunications network to utilize a common next-hop value of announced border gateway protocol (BGP) routes to advertise multiple routes to reach a destination customer network or address. By utilizing a common next-hop value in the announced BGP information, the devices of the network may load balance communication packets to the destination customer or address among the multiple egress locations from the network, as well as providing fast failover to alternate routes when a failure at the network or customer occurs.