Patents by Inventor David Coughlan

David Coughlan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190269639
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
    Type: Application
    Filed: February 19, 2019
    Publication date: September 5, 2019
    Inventors: Mehar Manku, John Climax, David Coughlan, James Dunne
  • Publication number: 20190224154
    Abstract: The present invention relates to the compositions comprising 15-HEPE and methods of treatment relating to same.
    Type: Application
    Filed: January 31, 2019
    Publication date: July 25, 2019
    Inventors: David Coughlan, John Climax
  • Publication number: 20190216761
    Abstract: The present disclosure relates to the compositions, formulations and methods of treating or preventing diseases mediated by peroxisome proliferator-activated receptors (PPARs) by administration of 15-HEPE.
    Type: Application
    Filed: January 11, 2019
    Publication date: July 18, 2019
    Inventors: John Climax, David Coughlan, Mehar Manku
  • Publication number: 20190175534
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and methods of using same to treat a variety of conditions and disorders.
    Type: Application
    Filed: October 11, 2018
    Publication date: June 13, 2019
    Inventors: Mehar Manku, John Climax, David Coughlan, James Dunne
  • Patent number: 10231945
    Abstract: The present invention relates to the compositions comprising 15-HEPE and methods of treatment relating to same.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: March 19, 2019
    Assignee: Afimmune Limited
    Inventors: David Coughlan, John Climax
  • Publication number: 20180333382
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and methods of using same to treat a variety of conditions and disorders.
    Type: Application
    Filed: May 17, 2018
    Publication date: November 22, 2018
    Inventors: John Climax, Mehar Manku, David Coughlan
  • Patent number: 10105333
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: October 23, 2018
    Assignee: DS BIOPHARMA LIMITED
    Inventors: Mehar Manku, John Climax, David Coughlan, James Dunne
  • Patent number: 10047033
    Abstract: The present disclosure provides 15-oxo-EPA and 15-oxo-DGLA, compositions comprising 15-oxo-EPA and/or 15-oxo-DGLA, and methods of treating and/or preventing fibrosis, skin disorders, inflammation, kidney disease or renal dysfunction in a subject in need thereof by administering 15-oxo-EPA and/or 15-oxo-DGLA.
    Type: Grant
    Filed: May 12, 2016
    Date of Patent: August 14, 2018
    Assignee: DS BIOPHARMA LIMITED
    Inventors: Mehar Manku, John Climax, David Coughlan
  • Publication number: 20180214408
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
    Type: Application
    Filed: March 26, 2018
    Publication date: August 2, 2018
    Inventors: Mehar Manku, John Climax, David Coughlan, James Dunne
  • Publication number: 20180201566
    Abstract: The present disclosure provides 15-oxo-EPA and 15-oxo-DGLA, compositions comprising 15-oxo-EPA and/or 15-oxo-DGLA, and methods of treating and/or preventing fibrosis, skin disorders, inflammation, kidney disease or renal dysfunction in a subject in need thereof by administering 15-oxo-EPA and/or 15-oxo-DGLA.
    Type: Application
    Filed: March 14, 2018
    Publication date: July 19, 2018
    Inventors: Mehar Manku, John Climax, David Coughlan
  • Patent number: 10017453
    Abstract: The present disclosure provides pharmaceutically acceptable stable salt forms of 15-lipoxygenase products, such as 15-HETrE lysine salt, compositions comprising same and methods of making and using same.
    Type: Grant
    Filed: November 17, 2014
    Date of Patent: July 10, 2018
    Assignee: DS BIOPHARMA LIMITED
    Inventors: Mehar Manku, David Coughlan, Bill Downes
  • Publication number: 20180147173
    Abstract: The present disclosure provides compositions comprising 15-HEPE and methods of using same for treating and/or preventing cancer and neurological diseases in a subject in need thereof.
    Type: Application
    Filed: January 25, 2018
    Publication date: May 31, 2018
    Inventors: John Climax, Mehar Manku, David Coughlan
  • Publication number: 20180118655
    Abstract: The present disclosure provides pharmaceutically acceptable stable salt forms of 15-lipoxygenase products, such as 15-HETrE lysine salt, compositions comprising same and methods of making and using same.
    Type: Application
    Filed: December 1, 2017
    Publication date: May 3, 2018
    Inventors: Mehar Manku, David Coughlan, Bill Downes
  • Publication number: 20180104208
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
    Type: Application
    Filed: December 14, 2017
    Publication date: April 19, 2018
    Inventors: Mehar Manku, John Climax, David Coughlan, James Dunne
  • Publication number: 20180104207
    Abstract: The present invention relates to the compositions comprising 15-HEPE and methods of treatment relating to same.
    Type: Application
    Filed: December 14, 2017
    Publication date: April 19, 2018
    Inventors: David Coughlan, John Climax
  • Publication number: 20180036272
    Abstract: The present disclosure provides orally deliverable pharmaceutical compositions comprising DGLA and to methods of using same to treat a variety of conditions and disorders.
    Type: Application
    Filed: July 27, 2017
    Publication date: February 8, 2018
    Inventors: Mehar Manku, John Climax, David Coughlan, James Dunne
  • Publication number: 20180008567
    Abstract: The present disclosure relates to the compositions, formulations and methods of treating or preventing diseases mediated by peroxisome proliferator-activated receptors (PPARs) by administration of 15-HEPE.
    Type: Application
    Filed: January 15, 2016
    Publication date: January 11, 2018
    Inventors: John Climax, David Coughlan, Mehar Manku
  • Patent number: 9855236
    Abstract: The present disclosure provides compositions comprising fatty acids, or derivatives thereof (e.g., C1-C4 esters) including, for example, DGLA, and/or 15-HETrE, used singly or in combination for the prevention and/or treatment of effects associated with UV radiation such as erythema.
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: January 2, 2018
    Assignee: DS BIOPHARMA LIMITED
    Inventors: Mehar Manku, John Climax, David Coughlan
  • Patent number: 9855238
    Abstract: The present invention relates to the compositions comprising 15-HEPE and methods of treatment relating to same.
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: January 2, 2018
    Assignee: AFIMMUNE LIMITED
    Inventors: David Coughlan, John Climax
  • Publication number: 20170232021
    Abstract: The present disclosure provides compositions and methods for the treatment of disease and/or disorders of this skin.
    Type: Application
    Filed: May 4, 2017
    Publication date: August 17, 2017
    Inventors: John Climax, Mehar Manku, David Coughlan