Patents by Inventor David Dornan

David Dornan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-CD79B Antibodies and Immunoconjugates and Methods of Use
    Publication number: 20190276550
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: August 22, 2013
    Publication date: September 12, 2019
    Applicant: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • Tank-binding kinase inhibitor compounds
    Patent number: 10316049
    Abstract: Compounds having the following formula (I) and methods of their use and preparation are disclosed:
    Type: Grant
    Filed: December 15, 2016
    Date of Patent: June 11, 2019
    Assignee: Gilead Sciences, Inc.
    Inventors: Zhimin Du, David Dornan, Juan A. Guerrero, Joshua A. Kaplan, John E. Knox, Devan Naduthambi, Barton W. Phillips, Susanna Y. Stinson, Chandrasekar Venkataramani, Peiyuan Wang, William J. Watkins
  • Anti-CD79B antibodies and immunoconjugates and methods of use
    Patent number: 9896506
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals, including immunoconjugates comprising anti-CD79b cysteine-engineered antibody huMA79b.v28, and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: June 9, 2015
    Date of Patent: February 20, 2018
    Assignee: GENENTECH, INC.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • METHODS OF TREATING HEPATITIS B VIRUS
    Publication number: 20180042905
    Abstract: The present invention relates to novel methods of treating Hepatitis B Virus by administering a KDM5 inhibitor.
    Type: Application
    Filed: August 29, 2017
    Publication date: February 15, 2018
    Inventors: Esmeralda Aguayo, Todd Appleby, Gabriel Birkus, Guofeng Cheng, David Dornan, Tetsuya Kobayashi, Christopher Charles Mello, Uli Schmitz, Madeleine Willkom, Mei Yu
  • TANK-BINDING KINASE INHIBITOR COMPOUNDS
    Publication number: 20170174713
    Abstract: Compounds having the following formula (I) and methods of their use and preparation are disclosed:
    Type: Application
    Filed: December 15, 2016
    Publication date: June 22, 2017
    Inventors: Zhimin Du, David Dornan, Juan A. Guerrero, Joshua A. Kaplan, John E. Knox, Devan Naduthambi, Barton W. Phillips, Susanna Y. Stinson, Chandrasekar Venkataramani, Peiyuan Wang, William J. Watkins
  • Methods for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies
    Patent number: 9617600
    Abstract: The invention provides methods and kits useful for predicting or assessing responsiveness of a patient having B-cell lymphoma to treatment with anti-CD40 antibodies.
    Type: Grant
    Filed: April 17, 2010
    Date of Patent: April 11, 2017
    Assignee: Genentech, Inc.
    Inventors: David Dornan, Bart Burington
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
    Publication number: 20170058032
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: November 11, 2016
    Publication date: March 2, 2017
    Applicant: Genentech, Inc.
    Inventors: Yvonne CHEN, Mark DENNIS, David DORNAN, Kristi ELKINS, Jagath Reddy JUNUTULA, Andrew POLSON, Bing ZHENG
  • METHODS OF TREATING HEPATITIS B VIRUS
    Publication number: 20160303095
    Abstract: The present invention relates to novel methods of treating Hepatitis B Virus by administering a KDM5 inhibitor.
    Type: Application
    Filed: April 13, 2016
    Publication date: October 20, 2016
    Inventors: Esmeralda Aguayo, Todd Appleby, Gabriel Birkus, Guofeng Cheng, David Dornan, Tetsuya Kobayashi, Christopher Charles Mello, Uli Schmitz, Madeleine Willkom, Mei Yu
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
    Publication number: 20150314016
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: June 9, 2015
    Publication date: November 5, 2015
    Applicant: GENENTECH, INC.
    Inventors: Yvonne CHEN, Mark DENNIS, David DORNAN, Kristi ELKINS, Jagath Reddy JUNUTULA, Andrew POLSON, Bing ZHENG
  • Methods and compositions for assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies
    Patent number: 9068230
    Abstract: The invention provides methods and kits useful for predicting or assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies.
    Type: Grant
    Filed: November 7, 2008
    Date of Patent: June 30, 2015
    Assignee: Genentech, Inc.
    Inventors: David Dornan, Bart Burington
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
    Publication number: 20140335107
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: March 19, 2014
    Publication date: November 13, 2014
    Applicant: GENENTECH, INC.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson
  • Anti-CD79B antibodies and immunoconjugates and methods of use
    Patent number: 8722857
    Abstract: The present invention is directed to cysteine-engineered anti-CD79b antibody, huMA79b.v28, and compositions of matter thereof useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: January 14, 2009
    Date of Patent: May 13, 2014
    Assignee: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson
  • Anti-CD79B Antibodies and Immunoconjugates and Methods of Use
    Publication number: 20140099260
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: August 22, 2013
    Publication date: April 10, 2014
    Applicant: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • Anti-CD79B antibodies and immunoconjugates and methods of use
    Patent number: 8691531
    Abstract: The present invention is directed to compositions of matter comprising nucleic acids encoding a polypeptide comprising the amino acid sequence of SEQ ID NO: 207 or 208, encoding an anti-CD79b antibody comprising the heavy chain variable domain sequence of SEQ ID NO: 207 and the light chain variable domain sequence of SEQ ID NO: 208, or encoding an anti-CD79b antibody having : (i) a variable light chain comprising a HVR-L1 having the sequence of SEQ ID NO: 194, a HVR-L2 having the sequence of SEQ ID NO: 195, and a HVR-L3 having the sequence of SEQ ID NO: 196 and (ii) a variable light chain comprising a HVR-H1 having the sequence of SEQ ID NO: 202, a HVR-H2 having the sequence of SEQ ID NO: 203, and a HVR-H3 having the sequence of SEQ ID NO: 204, and vectors and host cells thereof.
    Type: Grant
    Filed: November 28, 2011
    Date of Patent: April 8, 2014
    Assignee: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • CHRONIC LYMPHOCYTIC LEUKEMIA (CLL) BIOMARKERS
    Publication number: 20140017230
    Abstract: The present application describes chronic lymphocytic leukemia (CLL) biomarkers. In particular, the invention concerns miRNA151 3p, miRNA409 3p, PTK2, and/or PI3K as biomarkers for patient selection in CLL, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, and methods of advertising related thereto.
    Type: Application
    Filed: February 1, 2013
    Publication date: January 16, 2014
    Applicants: HOFFMANN-LA ROCHE INC., GENENTECH, INC.
    Inventors: DAVID DORNAN, GUILLEMETTE DUCHATEAU-NGUYEN, TRI QUANG NGUYEN, GIUSEPPE PALERMO, MARTIN WEISSER, RU-FANG YEH
  • Anti-CD79B antibodies and immunoconjugates and methods of use
    Patent number: 8545850
    Abstract: The present invention is directed to compositions of matter comprising immunoconjugates comprising an anti-CD79b antibody comprising: (i) an HVR-L1 sequence of KASQSVDYEGDSFLN (SEQ ID NO: 194), (ii) an HVR-L2 sequence of AASNLES (SEQ ID NO: 195), (iii) an HVR-L3 sequence of QQSNEDPLT (SEQ ID NO: 196), (iv) an HVR-H1 sequence of GYTFSSYWIE (SEQ ID NO: 202), (v) an HVR-H2 sequence of GEILPGGGDTNYNEIFKG (SEQ ID NO: 203), and (vi) an HVR-H3 sequence of TRRVPIRLDY (SEQ ID NO: 204) and to methods of using those compositions of matter for the treatment of hematopoietic tumor in mammals.
    Type: Grant
    Filed: November 5, 2010
    Date of Patent: October 1, 2013
    Assignee: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • Anti-CD79B Antibodies and Immunoconjugates and Methods of Use
    Publication number: 20120148600
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: November 28, 2011
    Publication date: June 14, 2012
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • METHODS FOR ASSESSING RESPONSIVENESS OF B-CELL LYMPHOMA TO TREATMENT WITH ANTI-CD40 ANTIBODIES
    Publication number: 20120123695
    Abstract: The invention provides methods and kits useful for predicting or assessing responsiveness of a patient having B-cell lymphoma to treatment with anti-CD40 antibodies.
    Type: Application
    Filed: April 17, 2010
    Publication date: May 17, 2012
    Inventors: David Dornan, Bart Burington
  • Anti-CD79B antibodies and immunoconjugates and methods of use
    Patent number: 8088378
    Abstract: The present invention is directed to anti-CD79b antibody, huMA79b.v28, and compositions of matter thereof useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: July 15, 2008
    Date of Patent: January 3, 2012
    Assignee: Genetech Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
    Publication number: 20110135667
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: November 5, 2010
    Publication date: June 9, 2011
    Applicant: GENENTECH, INC.
    Inventors: YVONNE CHEN, MARK DENNIS, DAVID DORNAN, KRISTI ELKINS, JAGATH REDDY JUNUTULA, ANDREW POLSON, BING ZHENG