Patents by Inventor David Dornan

David Dornan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR ASSESSING RESPONSIVENESS OF B-CELL LYMPHOMA TO TREATMENT WITH ANTI-CD40 ANTIBODIES
    Publication number: 20110104671
    Abstract: The invention provides methods and kits useful for predicting or assessing responsiveness of B-cell lymphoma to treatment with anti-CD40 antibodies.
    Type: Application
    Filed: November 7, 2008
    Publication date: May 5, 2011
    Inventors: David Dornan, Bart Burington
  • COPI MOLECULES AND USES THEREOF
    Publication number: 20110045474
    Abstract: The invention provides diagnostic, prognostic, and therapeutic uses for detecting COP1 overexpression in a variety of cancers. The methods and uses can further include detecting p53 expression. The invention also provides reagents and kits for use in screening for test compounds that interfere with COP1 and p53 binding.
    Type: Application
    Filed: June 29, 2010
    Publication date: February 24, 2011
    Inventors: David Dornan, Dorothy French, Vishva Dixit
  • COP1 molecules and uses thereof
    Patent number: 7785815
    Abstract: The invention provides diagnostic, prognostic, and therapeutic uses for detecting COP1 overexpression in a variety of cancers. The methods and uses can further include detecting p53 expression. The invention also provides reagents and kits for use in screening for test compounds that interfere with COP1 and p53 binding.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: August 31, 2010
    Assignee: Genentech, Inc.
    Inventors: David Dornan, Dorothy French, Vishva Dixit
  • ANTI-CD79B ANTIBODIES AND IMMUNOCONJUGATES AND METHODS OF USE
    Publication number: 20100215669
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: January 14, 2009
    Publication date: August 26, 2010
    Applicant: Genentech, Inc.
    Inventors: Yvonne CHEN, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson
  • Anti-CD79B Antibodies and Immunoconjugates and Methods of Use
    Publication number: 20090028856
    Abstract: The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: July 15, 2008
    Publication date: January 29, 2009
    Applicant: Genentech, Inc.
    Inventors: Yvonne Chen, Mark Dennis, David Dornan, Kristi Elkins, Jagath Reddy Junutula, Andrew Polson, Bing Zheng
  • Phosphorylated COP1 molecules and uses thereof
    Publication number: 20080027004
    Abstract: The invention provides COP1 molecules and modulators of COP1 activity and methods of using them, including diagnostic and therapeutic uses thereof. Such molecules can be useful for detecting DNA damage and modulating the response to DNA damage and p53 activity in subjects. The invention also provides reagents and kits for use in screening for test compounds that can modulate COP1 activity.
    Type: Application
    Filed: December 21, 2006
    Publication date: January 31, 2008
    Applicant: Genentech, Inc.
    Inventor: David Dornan
  • COP1 molecules and uses thereof
    Publication number: 20080009458
    Abstract: The invention provides diagnostic, prognostic, and therapeutic uses for detecting COP1 overexpression in a variety of cancers. The methods and uses can further include detecting p53 expression. The invention also provides reagents and kits for use in screening for test compounds that interfere with COP1 and p53 binding.
    Type: Application
    Filed: April 10, 2007
    Publication date: January 10, 2008
    Inventors: David Dornan, Dorothy French, Vishva Dixit
  • Screening methods and agents
    Publication number: 20040132108
    Abstract: The present invention relates to a method for screening for agents which modulate the binding of p53 to p300, and agents identified using such an assay. Such agents include peptide mimetics of regions of p53 and/or p300 which have been identified as contact region for the other protein. The agents of the present invention are candidates for use in the treatment of, for example cancer, or ischemia.
    Type: Application
    Filed: October 16, 2003
    Publication date: July 8, 2004
    Inventors: Theodore Robert Hupp, David Dornan