Patents by Inventor David E. Nichols

David E. Nichols has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING NEUROCOGNITIVE DISORDERS, CHRONIC PAIN AND REDUCING INFLAMMATION
    Publication number: 20220169668
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat neurocognitive disorders (e.g., Alzheimer's disease, Parkinson's disease), ADHD, Epilepsy, Autism, Sleep-wake disorders, Chronic pain, Inflammatory Disorders, IBD, Stroke, ALS, and/or Multiple Sclerosis.
    Type: Application
    Filed: April 17, 2020
    Publication date: June 2, 2022
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Megan CROAL, Hans Ake ERIKSSON, George GOLDSMITH, Molly Tabitha HICKEY, Shaun HURLEY, Ekaterina MALIEVSKAIA, Lindsey MARWOOD, Drummond E-Wen Joe MCCULLOCH, Laurie Emma MEDHURST, Nathan POULSEN, Aslihan SELIMBEYOGLU, Anais SOULA, Amanda Tan SHUXIANG, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE, Stephen WRIGHT
  • Pharmaceutically acceptable salts of psilocin and uses thereof
    Patent number: 11312684
    Abstract: The present invention composition features pharmaceutically acceptable salts of psilocin and compositions thereof. The pharmaceutically acceptable salts of psilocin may be used to treat a disease or condition, such as a neurological injury, an inflammatory condition, chronic pain, or a psychological condition, in a subject in need thereof.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: April 26, 2022
    Assignee: Eleusis Therapeutics US, Inc.
    Inventors: David E. Nichols, Graham Johnson, Hooshang S. Zavareh, Claire Wombwell, Daniel Rixson, Peter Haddow, Carrie Sheard, Alexander Schwarz
  • COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY DISORDERS
    Publication number: 20220119340
    Abstract: The invention features compounds and pharmaceutical compositions having anti-inflammatory properties. Also provided are methods of using the compounds or compositions of the invention for treating an inflammatory disorder in a subject in need thereof.
    Type: Application
    Filed: April 13, 2020
    Publication date: April 21, 2022
    Inventors: Charles D. Nichols, Gerald Billac, David E. Nichols
  • METHOD FOR TREATING ANXIETY DISORDERS, HEADACHE DISORDERS, AND EATING DISORDERS WITH PSILOCYBIN
    Publication number: 20220088041
    Abstract: The disclosure provides methods for treating a subject in need thereof comprising administering to the subject a therapeutically-effective dose of psilocybin. The methods described herein may be used to treat a variety of diseases, disorders, and conditions. For example, the methods may be used to treat anxiety disorders, eating disorders, and headache disorders.
    Type: Application
    Filed: December 2, 2021
    Publication date: March 24, 2022
    Applicant: COMPASS PATHFINDER LIMITED
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS, Megan CROAL, Hans Åke ERIKSSON, George GOLDSMITH, Molly Tabitha HICKEY, Shaun HURLEY, Ekaterina MALIEVSKAIA, Lindsey MARWOOD, Drummond E-Wen Joe MCCULLOCH, Laurie Emma MEDHURST, Nathan POULSEN, Aslihan SELIMBEYOGLU, Anaïs SOULA, Amanda Tan SHUXIANG, Manon Cecile Elisabeth VERAART, Tobias Patrick WHELAN, Lars Christian WILDE, Stephen WRIGHT
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20220073548
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. Move particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: November 19, 2021
    Publication date: March 10, 2022
    Applicant: COMPASS PATHFINDER LIMITED
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 11180517
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: April 13, 2021
    Date of Patent: November 23, 2021
    Assignee: COMPASS PATHFINDER LIMITED
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 11149044
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: October 19, 2021
    Assignee: COMPASS PATHFINDER LIMITED
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20210246152
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: April 13, 2021
    Publication date: August 12, 2021
    Applicant: COMPASS PATHFINDER LIMITED
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20210155642
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: February 10, 2021
    Publication date: May 27, 2021
    Applicant: COMPASS PATHFINDER LIMITED
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20210087212
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: December 9, 2020
    Publication date: March 25, 2021
    Applicant: COMPASS PATHFINDER LIMITED
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 10954259
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: March 23, 2021
    Assignee: COMPASS PATHFINDER LIMITED
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 10947257
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: March 16, 2021
    Assignee: COMPASS PATHFINDER LIMITED
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20200331939
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: July 2, 2020
    Publication date: October 22, 2020
    Applicant: COMPASS Pathways Limited
    Inventors: Derek John LONDESBROUGH, Christopher BROWN, Julian Scott NORTHEN, Gillian MOORE, Hemant Kashinath PATIL, David E. NICHOLS
  • PREPARATION OF PSILOCYBIN, DIFFERENT POLYMORPHIC FORMS, INTERMEDIATES, FORMULATIONS AND THEIR USE
    Publication number: 20200199161
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Application
    Filed: November 8, 2019
    Publication date: June 25, 2020
    Applicant: COMPASS Pathways Limited
    Inventors: Derek John LONDESBROUGH, CHRISTOPHER BROWN, JULIAN SCOTT NORTHEN, GILLIAN MOORE, HEMANT KASHINATH PATIL, DAVID E. NICHOLS
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 10519175
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: December 31, 2019
    Assignee: COMPASS Pathways Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols
  • Octahydrobenzoisoquinoline modulators of dopamine receptors and uses therefor
    Patent number: 9359303
    Abstract: Octahydrobenzoisoquinoline modulators of dopamine receptors are described herein. Methods for using octahydrobenzoisoquinoline modulators of dopamine receptors in the treatment of dopamine dysfunction are also described herein.
    Type: Grant
    Filed: April 21, 2010
    Date of Patent: June 7, 2016
    Assignee: Purdue Research Foundation
    Inventors: David E. Nichols, Val J. Watts
  • Generating an angle domain common image gather
    Patent number: 8760967
    Abstract: A technique includes processing first data indicative of a first image of a subsurface region of interest on a machine to generate second data indicative of a second image. The first image is derived from measurements of seismic waves, which propagate in a plurality of directions, and the second image is generated by partitioning the first image based on the directions. The technique includes processing the second data to determine a dip decomposition for each of the directions; and based on the dip decompositions and the directions, generating an angle domain common image gather.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: June 24, 2014
    Assignee: WesternGeco L.L.C.
    Inventors: David E. Nichols, Madhav Vyas, Everett C. Mobley
  • Fast residual migration of seismic data through parsimonious image decomposition
    Patent number: 8213260
    Abstract: A technique for performing a fast residual migration of seismic data through parsimonious image decomposition is presented. In one aspect, the technique includes a software-implemented method for processing a set of seismic data includes through parsimonious image decomposition. Other aspects of the technique include a program storage medium encoded with instructions that, when executed by a processor, perform such a method or a computing apparatus programmed to perform such a method.
    Type: Grant
    Filed: April 7, 2009
    Date of Patent: July 3, 2012
    Assignee: WesternGeco L.L.C.
    Inventor: David E. Nichols
  • Generating an Angle Domain Common Image Gather
    Publication number: 20120092962
    Abstract: A technique includes processing first data indicative of a first image of a subsurface region of interest on a machine to generate second data indicative of a second image. The first image is derived from measurements of seismic waves, which propagate in a plurality of directions, and the second image is generated by partitioning the first image based on the directions. The technique includes processing the second data to determine a dip decomposition for each of the directions; and based on the dip decompositions and the directions, generating an angle domain common image gather.
    Type: Application
    Filed: April 6, 2011
    Publication date: April 19, 2012
    Inventors: David E. Nichols, Madhav Vyas, Everett C. Mobley
  • OCTAHYDROBENZOISOQUINOLINE MODULATORS OF DOPAMINE RECEPTORS AND USES THEREFOR
    Publication number: 20120041018
    Abstract: Octahydrobenzoisoquinoline modulators of dopamine receptors are described herein. Methods for using octahydrobenzoisoquinoline modulators of dopamine receptors in the treatment of dopamine dysfunction are also described herein.
    Type: Application
    Filed: April 21, 2010
    Publication date: February 16, 2012
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: David E. Nichols, Val J. Watts