Patents by Inventor David Estell

David Estell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11091750
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: August 17, 2021
    Assignee: DANISCO US INC
    Inventors: Andrew Shaw, David A Estell, Eugene S Sadlowski, Hiroshi Oh, Louise Wallace, Ronaldus Wilhelmus Joannes Hommes, Sang-Kyu Lee
  • Publication number: 20210214703
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: May 24, 2019
    Publication date: July 15, 2021
    Inventors: Viktor Yuryevich ALEKSEYEV, Lilia Maria BABE, Billur H. ENGIN, David A. ESTELL, Frits GOEDEGEBUUR, Thijs KAPER, Harm MULDER, Sina PRICELIUS, Sander Van Stigt THANS
  • Patent number: 11053488
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, where the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising the cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding the cellulase variants, or active fragments thereof; and methods for making and/or using the cellulase variants, or active fragments thereof and/or compositions containing same; where the cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Grant
    Filed: December 14, 2017
    Date of Patent: July 6, 2021
    Assignee: DANISCO US INC
    Inventors: Richard Bott, David A. Estell, Neeraj Pandey, Sina Pricelius, Jian Yao
  • Publication number: 20210071113
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Application
    Filed: November 18, 2020
    Publication date: March 11, 2021
    Inventors: Philip Frank SOUTER, Glenn Steven WARD, Viktor Yuryevich ALEKSEYEV, Joshua Roy BASLER, Luis Gustavo CASCAO-PEREIRA, David A ESTELL, Ayrookaran J Poulose, James T KELLIS, Jr., Alexander PISARCHIK, Daniel TORRES-PAZMINO
  • Patent number: 10920204
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Grant
    Filed: June 13, 2018
    Date of Patent: February 16, 2021
    Assignee: DANISCO US INC
    Inventors: Ayrookaran J. Poulose, Thomas P. Graycar, Sina Pricelius, David A. Estell
  • Patent number: 10900000
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: January 26, 2021
    Assignee: The Procter & Gamble Company
    Inventors: Philip Frank Souter, Glenn Steven Ward, Viktor Yuryevich Alekseyev, Joshua Roy Basler, Luis Gustavo Cascao-Pereira, David A Estell, Ayrookaran J Poulose, James T Kellis, Jr., Alexander Pisarchik, Daniel Torres-Pazmino
  • Patent number: 10870839
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having two, three, or more modifications as compared to a parent lipolytic enzyme and having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Grant
    Filed: April 11, 2019
    Date of Patent: December 22, 2020
    Assignee: DANISCO US INC
    Inventors: Thomas P. Graycar, Ayrookaran J. Poulose, David A. Estell
  • Publication number: 20200392477
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: December 19, 2017
    Publication date: December 17, 2020
    Inventors: Lilia Maria Babe, Lydia Dankmeyer, David A. Estell, Frits Goedegebuur, Thijs Kaper, Harm Mulder, Sina Pricelius
  • Patent number: 10865398
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: December 15, 2020
    Assignee: DANISCO US INC
    Inventors: Thomas P. Graycar, David A. Estell, Ayrookaran J. Poulose, Sina Pricelius
  • Publication number: 20200354705
    Abstract: Aspects of the present disclosure include glucoamylase (GA) variants having at least one improved property over a parent GA, compositions containing the GA variants, nucleic acids encoding the GA variants, and methods for producing and using the same. In some aspects, the GA variant is a variant of a parent GA from Humicola grisea.
    Type: Application
    Filed: March 9, 2020
    Publication date: November 12, 2020
    Inventors: DANIEL ESTEBAN TORRES PAZMINO, VIKTOR YURYEVICH ALEKSEYEV, CASPER WILLEM VROEMEN, DAVID A. ESTELL
  • Publication number: 20200354708
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability compared to one or more reference subtilisin.
    Type: Application
    Filed: November 28, 2018
    Publication date: November 12, 2020
    Inventors: Lilia Maria Babe, Viktor Yuryevich Alekseyev, Joshua Roy Basler, H. Billur Engin, David A. Estell, Roopa Santosh Ghirnikar, Frits Goedegebuur, Thijs Kaper, Mulder Harm, Sina Pricelius, Thans Sander Van Stigt
  • Publication number: 20200332229
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: May 31, 2017
    Publication date: October 22, 2020
    Applicant: Danisco US Inc.
    Inventors: David MARQUEZ, Michael STONER, James T. KELLIS, JR., Adam GARSKE, Joshua Roy BASLER, Katherine AUGUSTYN, Priyanka CHANDRASEKARAN, Miles Christopher SCOTCHER, Lilia Maria BABE, Richard R. BOTT, David A. ESTELL, Gudrun VOGTENTANZ, Sina PRICELIUS, Jian YAO
  • Publication number: 20200299618
    Abstract: The present invention provides consumer products comprising a serine protease variant, more specifically subtilisin variants produced there from. Specifically, the present invention provides consumer products comprising a serine protease variant, more specifically a subtilisin variant having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides methods of making such compositions and methods of treating surfaces, particularly fabric surfaces comprising contacting a surface with an aqueous liquor comprising a serine protease variant, more specifically subtilisin variants and an adjunct material.
    Type: Application
    Filed: June 4, 2020
    Publication date: September 24, 2020
    Inventors: Philip Frank SOUTER, Euan John MAGENNIS, Glenn Steven WARD, Neelam S. AMIN, Katherine AUGUSTYN, Joshua R. BASLER, Luis Gustavo CASCAO-PEREIRA, Katherine D. COLLIER, Edward M. CONCAR, David A. ESTELL, James T. KELLIS, Alexander PISARCHIK, Ayrookaran Joseph POULOSE, Jian YAO
  • Publication number: 20200123522
    Abstract: The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.
    Type: Application
    Filed: December 19, 2019
    Publication date: April 23, 2020
    Inventors: David A Estell, Frits Goedegebuur, Marc Anton Bernhard Kolkman, Rie Mejldal, Katherine Augustyn, Lilia Maria Babe, Richard R Bott, Jian Yao, Roopa Santosh Ghirnikar
  • Publication number: 20200080069
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Application
    Filed: November 25, 2019
    Publication date: March 12, 2020
    Inventors: Ayrookaran J. Poulose, Joshua Roy Basler, Luis G. Cascao-Pereira, James T. Kellis, JR., Alexander Pisarchik, Daniel Esteban Torres Pazmino, David A. Estell
  • Patent number: 10584323
    Abstract: Aspects of the present disclosure include glucoamylase (GA) variants having at least one improved property over a parent GA, compositions containing the GA variants, nucleic acids encoding the GA variants, and methods for producing and using the same. In some aspects, the GA variant is a variant of a parent GA from Humicola grisea.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: March 10, 2020
    Assignee: DANISCO US INC
    Inventors: Daniel Esteban Torres Pazmino, Viktor Yuryevich Alekseyev, Casper Willem Vroemen, David A. Estell
  • Patent number: 10577595
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: March 3, 2020
    Assignee: DANISCO US INC
    Inventors: Andrew Shaw, David A Estell, Eugene S Sadlowski, Hiroshi Oh, Louise Wallace, Ronaldus Wilhelmus Joannes Hommes, Sang-Kyu Lee
  • Publication number: 20200056165
    Abstract: The present invention provides methods and compositions comprising at least one neutral metalloprotease enzyme that has improved storage stability. In some embodiments, the neutral metalloprotease finds use in cleaning and other applications. In some particularly preferred embodiments, the present invention provides methods and compositions comprising neutral metalloprotease(s) obtained from Bacillus sp. In some more particularly preferred embodiments, the neutral metalloprotease is obtained from B. amyloliquefaciens. In still further preferred embodiments, the neutral metalloprotease is a variant of the B. amyloliquefaciens neutral metalloprotease. In yet additional embodiments, the neutral metalloprotease is a homolog of the the B. amyloliquefaciens neutral metalloprotease. The present invention finds particular use in applications including, but not limited to cleaning, bleaching and disinfecting.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 20, 2020
    Inventors: ANDREW SHAW, DAVID A ESTELL, EUGENE S SADLOWSKI, HIROSHI OH, LOUISE WALLACE, RONALDUS WILHELMUS JOAN HOMMES, SANG-KYU LEE
  • Patent number: 10563189
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications.
    Type: Grant
    Filed: November 10, 2014
    Date of Patent: February 18, 2020
    Assignee: The Procter & Gamble Company
    Inventors: Joshua R. Basler, Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, Jr.
  • Publication number: 20200002693
    Abstract: Disclosed are compositions and methods relating to variant maltohexaose-forming alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.
    Type: Application
    Filed: September 17, 2019
    Publication date: January 2, 2020
    Inventors: Luis G. Cascao-Pereira, David A. Estell, Marc Anton Bernhard Kolkman, Harm Mulder