Patents by Inventor David Estell

David Estell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYPEPTIDES WITH ENDOGLUCANASE ACTIVITY AND USES THEREOF
    Publication number: 20190367894
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, wherein the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising said cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding said cellulase variants, or active fragments thereof; and methods for making and/or using said cellulase variants, or active fragments thereof and/or compositions containing same; wherein said cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Application
    Filed: December 14, 2017
    Publication date: December 5, 2019
    Inventors: Richard R. Bott, David A. Estell, Neeraj Pandey, Sina Pricelius, Jian Yao
  • Variant maltohexaose-forming alpha-amylase variants
    Patent number: 10457924
    Abstract: Disclosed are compositions and methods relating to variant maltohexaose-forming alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: October 29, 2019
    Assignee: DANISCO US INC
    Inventors: Luis G. Cascao-Pereira, David A. Estell, Marc Kolkman, Harm Mulder
  • PROTEASE VARIANTS AND USES THEREOF
    Publication number: 20190309278
    Abstract: Disclosed herein is one or more subtilisin variants, nucleic acids encoding same, and compositions and methods related to the production and uses thereof, including one or more subtilisin variants that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: June 18, 2017
    Publication date: October 10, 2019
    Inventors: Richard R. Bott, David A. Estell, Frits Goedegebuur, Harm Mulder, Sina Pricelius
  • AUTOMATIC DISHWASHING DETERGENT COMPOSITION
    Publication number: 20190276813
    Abstract: The present invention is in the field of automatic dishwashing detergent compositions, as well as methods of making and using same. In particular, it relates to an automatic dishwashing detergent composition comprising a new protease. The automatic dishwashing detergent composition provides improved cleaning and finishing. In particular the composition of the invention provides better proteinaceous removal at the same level of other proteases available in the market. This also alternatively allows for the use of a lower level of the protease of the invention and therefore a more cost effective composition.
    Type: Application
    Filed: May 9, 2019
    Publication date: September 12, 2019
    Inventors: Philip Frank SOUTER, Glenn Steven WARD, Frits (NMN) GOEDEGEBUUR, Ayrookaran Joseph POULOSE, David A. ESTELL, Richard Ray BOTT, Luis Gustavo CASCAO-PEREIRA
  • COMPOSITIONS AND METHODS COMPRISING A LIPOLYTIC ENZYME VARIANT
    Publication number: 20190233804
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having two, three, or more modifications as compared to a parent lipolytic enzyme and having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Application
    Filed: April 11, 2019
    Publication date: August 1, 2019
    Inventors: Thomas P Graycar, Ayrookaran J. Poulose, David A. Estell
  • PROTEASE VARIANTS AND USES THEREOF
    Publication number: 20190194636
    Abstract: Disclosed herein is one or more subtilisin variant useful for cleaning applications and in methods of cleaning. One embodiment is directed to one or more subtilisin variant, including one or more Bacillus sp. subtilisin polypeptide variant, and one or more cleaning composition comprising one or more such variant.
    Type: Application
    Filed: May 3, 2017
    Publication date: June 27, 2019
    Inventors: Lilia Maria Babe, Joshua Roy Basler, David A. Estell, Viktor Yuryevich Alekseyev, David Edward Wildes, Jeffrey Wayne Munos, Neelam S. Amin, David Marquez, Victoria Huang, Geetha Veeramuthu, Rei Otsuka, Philip F. Souter, David John Tarbit, Michelle Jackson, Eva Maria Perez-Prat Vinuesa, Euan John Magennis
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20190194577
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: September 7, 2018
    Publication date: June 27, 2019
    Inventors: LUIS G. CASCAO-PEREIRA, DAVID A. ESTELL, FRITS GOEDEGEBUUR, JAMES T. KELLIS, JR., AYROOKARAN J. POULOSE, BRIAN F. SCHMIDT, WOLFGANG AEHLE
  • Compositions and methods comprising a lipolytic enzyme variant
    Patent number: 10329546
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having two, three, or more modifications as compared to a parent lipolytic enzyme and having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: June 25, 2019
    Assignee: DANISCO US INC
    Inventors: Thomas P. Graycar, Ayrookaran J. Poulose, David A. Estell
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20190136217
    Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: July 10, 2018
    Publication date: May 9, 2019
    Inventors: Viktor Yuryevich Alekseyev, Neelam S. Amin, Luis G. Cascao-Pereira, Katherine D. Collier, David A. Estell, James T. Kellis, JR., Ayrookaran J. Poulose, Philip F. Souter, Glenn S. Ward, Katherine Augustyn, Jian Yao
  • COMPOSITIONS AND METHODS COMPRISING A LIPOLYTIC ENZYME VARIANT
    Publication number: 20190024064
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Application
    Filed: October 9, 2018
    Publication date: January 24, 2019
    Inventors: Thomas P. Graycar, David A. Estell, Ayrookaran J. Poulose, Sina Pricelius
  • AUTOMATIC DISHWASHING DETERGENT COMPOSITION
    Publication number: 20180355340
    Abstract: The present invention is in the field of automatic dishwashing detergent compositions, as well as methods of making and using same. In particular, it relates to an automatic dishwashing detergent composition comprising a new protease. The automatic dishwashing detergent composition provides improved cleaning and finishing. In particular the composition of the invention provides better proteinaceous removal at the same level of other proteases available in the market. This also alternatively allows for the use of a lower level of the protease of the invention and therefore a more cost effective composition.
    Type: Application
    Filed: August 23, 2018
    Publication date: December 13, 2018
    Inventors: Philip Frank SOUTER, Glenn Steven WARD, Frits GOEDEGEBUUR, Ayrookaran Joseph POULOSE, David A. ESTELL, Richard Ray BOTT, Luis Gustavo CASCAO-PEREIRA
  • COMPOSITIONS AND METHODS COMPRISING A LIPOLYTIC ENZYME VARIANT
    Publication number: 20180291356
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Application
    Filed: June 13, 2018
    Publication date: October 11, 2018
    Inventors: Ayrookaran J. Poulose, Thomas P. Graycar, Sina Pricelius, David A. Estell
  • Compositions and methods comprising serine protease variants
    Patent number: 10093887
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Grant
    Filed: July 21, 2014
    Date of Patent: October 9, 2018
    Assignee: DANISCO US INC.
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, Jr., Ayrookaran J. Poulose, Brian F. Schmidt
  • THERMOLYSIN VARIANTS
    Publication number: 20180251742
    Abstract: The present invention provides methods and compositions comprising at least one thermolysin-like neutral protease enzyme with improved storage stability and/or catalytic activity. In some embodiments, the thermolysin finds use in cleaning and other applications comprising detergent. In some particularly preferred embodiments, the present invention provides methods and compositions comprising thermolysin formulated and/or engineered to resist detergent-induced inactivation.
    Type: Application
    Filed: May 3, 2018
    Publication date: September 6, 2018
    Inventors: DAVID A. ESTELL, AMY D. LIU, RONALDUS W.J. HOMMES, ANDREW SHAW
  • BACILLUS GIBSONII-CLADE SERINE PROTEASES
    Publication number: 20180237761
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more Bacillus gibsonii-clade subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: June 17, 2016
    Publication date: August 23, 2018
    Inventors: Lilia Maria Babe, Richard R. Bott, David A. Estell, Harm Mulder, Frits Goedegebuur, Jian Yao, Sina Pricelius, Miles Scotcher
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20180216092
    Abstract: The present invention provides serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: December 5, 2017
    Publication date: August 2, 2018
    Inventors: VIKTOR YURYEVICH ALEKSEYEV, Neelam S. Amin, Luis G. Cascao-Pereira, Katherine D. Collier, David A. Estell, James T. Kellis, JR., Ayrookaran J. Poulose, Philip F. Souter, Glenn S. Ward, Katherine Augustyn, Jian Yao
  • COMPOSITIONS AND METHODS COMPRISING LG12-CLADE PROTEASE VARIANTS
    Publication number: 20180216090
    Abstract: The present disclosure provides LG12-clade enzyme variants, compositions comprising these enzyme variants, and method of using these enzymes and compositions, as well as the polynucleotides encoding these enzymes, the vectors comprising these polynucleotides, and the host cells transformed with such vectors.
    Type: Application
    Filed: March 14, 2016
    Publication date: August 2, 2018
    Inventors: Harm Mulder, Jeffrey Veach Miller, Frits Goedegebuur, David A. Estell, Katherine Augustyn, Lilia Maria Babe, Richard R. Bott, Miles Christopher Scotcher, Jian Yao
  • Compositions and methods comprising a lipolytic enzyme variant
    Patent number: 10023851
    Abstract: The present invention provides lipolytic enzyme variants. Specifically, the present invention provides lipolytic enzyme variants having one or more modifications as compared to a parent lipolytic enzyme having at least one improved property. In addition, the present invention provides compositions comprising a lipolytic enzyme variant of the invention. The present invention also provides methods of cleaning using compositions comprising a lipolytic enzyme variant of the invention.
    Type: Grant
    Filed: October 11, 2013
    Date of Patent: July 17, 2018
    Assignee: DANISCO US INC.
    Inventors: Thomas P. Graycar, Sina Pricelius, Ayrookaran J. Poulose, David A. Estell
  • FABRIC AND HOME CARE PRODUCTS
    Publication number: 20180171268
    Abstract: This invention relates to fabric and home care products comprising one or more cold water proteases and processes for making and using such products. Such compositions provide improved cleaning and freshness. Such cold water proteases may be derived from parent enzymes, including BPN? subtilisin and subtilisin derived from Bacillus lentus, by substitution, insertion and/or deletion of one or more of the parent enzymes' amino acids.
    Type: Application
    Filed: December 13, 2017
    Publication date: June 21, 2018
    Inventors: Philip Frank Souter, Glenn Steven Ward, Viktor Yuryevich Alekseyev, Joshua Roy Basler, Luis Gustavo Cascao-Pereira, David A Estell, Ayrookaran J Poulose, James T Kellis, JR., Alexander Pisarchik, Daniel Torres-Pazmino
  • Thermolysin variants
    Patent number: 9976134
    Abstract: The present invention provides methods and compositions comprising at least one thermolysin-like neutral protease enzyme with improved storage stability and/or catalytic activity. In some embodiments, the thermolysin finds use in cleaning and other applications comprising detergent. In some particularly preferred embodiments, the present invention provides methods and compositions comprising thermolysin formulated and/or engineered to resist detergent-induced inactivation.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: May 22, 2018
    Assignee: DANISCO US INC.
    Inventors: David A. Estell, Ronaldus W. J. Hommes, Amy D. Liu, Andrew Shaw